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Items: 1 to 20 of 370

1.

CTLA-4 as immunological checkpoint in the development of multiple sclerosis.

Gerdes LA, Held K, Beltran E, Berking C, Prinz JC, Junker A, Tietze JK, Ertl-Wagner B, Straube A, Kümpfel T, Dornmair K, Hohlfeld R.

Ann Neurol. 2016 Jun 28. doi: 10.1002/ana.24715. [Epub ahead of print]

PMID:
27351142
2.

Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins.

Brändle SM, Obermeier B, Senel M, Bruder J, Mentele R, Khademi M, Olsson T, Tumani H, Kristoferitsch W, Lottspeich F, Wekerle H, Hohlfeld R, Dornmair K.

Proc Natl Acad Sci U S A. 2016 Jun 20. pii: 201522730. [Epub ahead of print]

PMID:
27325759
3.

Multiple sclerosis: Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor.

Rühl G, Niedl AG, Patronov A, Siewert K, Pinkert S, Kalemanov M, Friese MA, Attfield KE, Antes I, Hohlfeld R, Dornmair K.

Neurol Neuroimmunol Neuroinflamm. 2016 May 17;3(4):e241. doi: 10.1212/NXI.0000000000000241. eCollection 2016 Aug.

4.

Cytotoxic T cells go awry in inclusion body myositis.

Hohlfeld R, Schulze-Koops H.

Brain. 2016 May;139(Pt 5):1312-4. doi: 10.1093/brain/aww053. No abstract available.

PMID:
27189577
5.

Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation.

Gross CC, Schulte-Mecklenbeck A, Rünzi A, Kuhlmann T, Posevitz-Fejfár A, Schwab N, Schneider-Hohendorf T, Herich S, Held K, Konjević M, Hartwig M, Dornmair K, Hohlfeld R, Ziemssen T, Klotz L, Meuth SG, Wiendl H.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):E2973-82. doi: 10.1073/pnas.1524924113. Epub 2016 May 9.

PMID:
27162345
6.

Mitochondrial DNA Variation and Heteroplasmy in Monozygotic Twins Clinically Discordant for Multiple Sclerosis.

Souren NY, Gerdes LA, Kümpfel T, Lutsik P, Klopstock T, Hohlfeld R, Walter J.

Hum Mutat. 2016 Apr 27. doi: 10.1002/humu.23003. [Epub ahead of print]

PMID:
27119776
7.

Alemtuzumab and Multiple Sclerosis: Another Note of Caution.

Hohlfeld R, Kümpfel T.

JAMA Neurol. 2016 Jun 1;73(6):637-8. doi: 10.1001/jamaneurol.2016.0259. No abstract available.

PMID:
27042804
8.

Leitlinie Dermatomyositis - Auszug aus der interdisziplinären S2k-Leitlinie zu Myositissyndromen der deutschen Gesellschaft für Neurologie.

Sunderkötter C, Nast A, Worm M, Dengler R, Dörner T, Ganter H, Hohlfeld R, Melms A, Melzer N, Rösler K, Schmidt J, Sinnreich M, Walter MC, Wanschitz J, Wiendl H.

J Dtsch Dermatol Ges. 2016 Mar;14(3):e1-e20. doi: 10.1111/ddg.12909_g.

PMID:
26972220
9.

Guidelines on dermatomyositis - excerpt from the interdisciplinary S2k guidelines on myositis syndromes by the German Society of Neurology.

Sunderkötter C, Nast A, Worm M, Dengler R, Dörner T, Ganter H, Hohlfeld R, Melms A, Melzer N, Rösler K, Schmidt J, Sinnreich M, Walter MC, Wanschitz J, Wiendl H.

J Dtsch Dermatol Ges. 2016 Mar;14(3):321-38. doi: 10.1111/ddg.12909.

PMID:
26972210
10.

[Monitoring of blood parameters under course-modified MS therapy : Substance-specific relevance and current recommendations for action].

Klotz L, Berthele A, Brück W, Chan A, Flachenecker P, Gold R, Haghikia A, Hellwig K, Hemmer B, Hohlfeld R, Korn T, Kümpfel T, Lang M, Limmroth V, Linker RA, Meier U, Meuth SG, Paul F, Salmen A, Stangel M, Tackenberg B, Tumani H, Warnke C, Weber MS, Ziemssen T, Zipp F, Wiendl H.

Nervenarzt. 2016 Jun;87(6):645-59. doi: 10.1007/s00115-016-0077-1. German.

PMID:
26927677
11.

Clinical features, pathogenesis, and treatment of myasthenia gravis: a supplement to the Guidelines of the German Neurological Society.

Melzer N, Ruck T, Fuhr P, Gold R, Hohlfeld R, Marx A, Melms A, Tackenberg B, Schalke B, Schneider-Gold C, Zimprich F, Meuth SG, Wiendl H.

J Neurol. 2016 Feb 17. [Epub ahead of print]

PMID:
26886206
12.

Oral fingolimod in primary progressive multiple sclerosis (INFORMS): a phase 3, randomised, double-blind, placebo-controlled trial.

Lublin F, Miller DH, Freedman MS, Cree BA, Wolinsky JS, Weiner H, Lubetzki C, Hartung HP, Montalban X, Uitdehaag BM, Merschhemke M, Li B, Putzki N, Liu FC, Häring DA, Kappos L; INFORMS study investigators.

Lancet. 2016 Mar 12;387(10023):1075-84. doi: 10.1016/S0140-6736(15)01314-8. Epub 2016 Jan 28.

PMID:
26827074
13.

The search for the target antigens of multiple sclerosis, part 1: autoreactive CD4+ T lymphocytes as pathogenic effectors and therapeutic targets.

Hohlfeld R, Dornmair K, Meinl E, Wekerle H.

Lancet Neurol. 2015 Dec 23. pii: S1474-4422(15)00334-8. doi: 10.1016/S1474-4422(15)00334-8. [Epub ahead of print] Review.

PMID:
26724103
14.

The search for the target antigens of multiple sclerosis, part 2: CD8+ T cells, B cells, and antibodies in the focus of reverse-translational research.

Hohlfeld R, Dornmair K, Meinl E, Wekerle H.

Lancet Neurol. 2016 Mar;15(3):317-31. doi: 10.1016/S1474-4422(15)00313-0. Epub 2015 Dec 24. Review.

PMID:
26724102
15.

Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid.

Wuhrer M, Selman MH, McDonnell LA, Kümpfel T, Derfuss T, Khademi M, Olsson T, Hohlfeld R, Meinl E, Krumbholz M.

J Neuroinflammation. 2015 Dec 18;12:235. doi: 10.1186/s12974-015-0450-1.

16.

PML risk stratification using anti-JCV antibody index and L-selectin.

Schwab N, Schneider-Hohendorf T, Pignolet B, Spadaro M, Görlich D, Meinl I, Windhagen S, Tackenberg B, Breuer J, Cantó E, Kümpfel T, Hohlfeld R, Siffrin V, Luessi F, Posevitz-Fejfár A, Montalban X, Meuth SG, Zipp F, Gold R, Du Pasquier RA, Kleinschnitz C, Jacobi A, Comabella M, Bertolotto A, Brassat D, Wiendl H.

Mult Scler. 2015 Oct 2. pii: 1352458515607651. [Epub ahead of print]

PMID:
26432858
17.

Fingolimod induces neuroprotective factors in human astrocytes.

Hoffmann FS, Hofereiter J, Rübsamen H, Melms J, Schwarz S, Faber H, Weber P, Pütz B, Loleit V, Weber F, Hohlfeld R, Meinl E, Krumbholz M.

J Neuroinflammation. 2015 Sep 30;12:184. doi: 10.1186/s12974-015-0393-6.

18.

T-cell receptor repertoire of human peripheral CD161hiTRAV1-2+ MAIT cells revealed by next generation sequencing and single cell analysis.

Held K, Beltrán E, Moser M, Hohlfeld R, Dornmair K.

Hum Immunol. 2015 Sep;76(9):607-14. doi: 10.1016/j.humimm.2015.09.002. Epub 2015 Sep 14.

PMID:
26382249
19.

[Current aspects of therapy conversion for multiple sclerosis].

Kolber P, Luessi F, Meuth SG, Klotz L, Korn T, Trebst C, Tackenberg B, Kieseier B, Kümpfel T, Fleischer V, Tumani H, Wildemann B, Lang M, Flachenecker P, Meier U, Brück W, Limmroth V, Haghikia A, Hartung HP, Stangel M, Hohlfeld R, Hemmer B, Gold R, Wiendl H, Zipp F.

Nervenarzt. 2015 Oct;86(10):1236-47. doi: 10.1007/s00115-015-4368-8. German.

PMID:
26269289
20.

[Multiple sclerosis and microbiota. From genome to metagenome?].

Hohlfeld R, Wekerle H.

Nervenarzt. 2015 Aug;86(8):925-33. doi: 10.1007/s00115-014-4248-7. German.

PMID:
26099498
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