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Melanoma miRNA trafficking controls tumour primary niche formation.

Dror S, Sander L, Schwartz H, Sheinboim D, Barzilai A, Dishon Y, Apcher S, Golan T, Greenberger S, Barshack I, Malcov H, Zilberberg A, Levin L, Nessling M, Friedmann Y, Igras V, Barzilay O, Vaknine H, Brenner R, Zinger A, Schroeder A, Gonen P, Khaled M, Erez N, Hoheisel JD, Levy C.

Nat Cell Biol. 2016 Aug 22. doi: 10.1038/ncb3399. [Epub ahead of print]


Secretome profiling of apheresis platelet supernatants during routine storage via antibody-based microarray.

Kamhieh-Milz J, Mustafa SA, Sterzer V, Celik H, Keski S, Khorramshahi O, Movassaghi K, Hoheisel JD, Alhamdani MS, Salama A.

J Proteomics. 2016 Jul 28. pii: S1874-3919(16)30337-2. doi: 10.1016/j.jprot.2016.07.028. [Epub ahead of print]


Early Epigenetic Downregulation of microRNA-192 Expression Promotes Pancreatic Cancer Progression.

Botla SK, Savant S, Jandaghi P, Bauer AS, Mücke O, Moskalev EA, Neoptolemos JP, Costello E, Greenhalf W, Scarpa A, Gaida MM, Büchler MW, Strobel O, Hackert T, Giese NA, Augustin HG, Hoheisel JD.

Cancer Res. 2016 May 23. [Epub ahead of print]


Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of LKB1 and activation of AMPK in PDACs.

Cheng X, Kim JY, Ghafoory S, Duvaci T, Rafiee R, Theobald J, Alborzinia H, Holenya P, Fredebohm J, Merz KH, Mehrabi A, Hafezi M, Saffari A, Eisenbrand G, Hoheisel JD, Wölfl S.

Mol Oncol. 2016 Jun;10(6):806-24. doi: 10.1016/j.molonc.2016.01.008. Epub 2016 Feb 4.


Gene expression regulatory networks in Trypanosoma brucei: insights into the role of the mRNA-binding proteome.

Lueong S, Merce C, Fischer B, Hoheisel JD, Erben ED.

Mol Microbiol. 2016 May;100(3):457-71. doi: 10.1111/mmi.13328. Epub 2016 Mar 10.


Utilisation of antibody microarrays for the selection of specific and informative antibodies from recombinant library binders of unknown quality.

Kibat J, Schirrmann T, Knape MJ, Helmsing S, Meier D, Hust M, Schröder C, Bertinetti D, Winter G, Pardes K, Funk M, Vala A, Giese N, Herberg FW, Dübel S, Hoheisel JD.

N Biotechnol. 2016 Sep 25;33(5 Pt A):574-81. doi: 10.1016/j.nbt.2015.12.003. Epub 2015 Dec 17.


Boc-SPPS: Compatible Linker for the Synthesis of Peptide o-Aminoanilides.

Weidmann J, Dimitrijević E, Hoheisel JD, Dawson PE.

Org Lett. 2016 Jan 15;18(2):164-7. doi: 10.1021/acs.orglett.5b03111. Epub 2015 Dec 24.


Identification of novel biomarkers in chronic immune thrombocytopenia (ITP) by microarray-based serum protein profiling.

Bal G, Futschik ME, Hartl D, Ringel F, Kamhieh-Milz J, Sterzer V, Hoheisel JD, Alhamdani MS, Salama A.

Br J Haematol. 2016 Feb;172(4):602-15. doi: 10.1111/bjh.13861. Epub 2015 Dec 2.


Definition of a serum marker panel for glioblastoma discrimination and identification of Interleukin 1β in the microglial secretome as a novel mediator of endothelial cell survival induced by C-reactive protein.

Nijaguna MB, Schröder C, Patil V, Shwetha SD, Hegde AS, Chandramouli BA, Arivazhagan A, Santosh V, Hoheisel JD, Somasundaram K.

J Proteomics. 2015 Oct 14;128:251-61. doi: 10.1016/j.jprot.2015.07.026. Epub 2015 Jul 29.


Stratification of pancreatic tissue samples for molecular studies: RNA-based cellular annotation procedure.

Heller A, Gaida MM, Männle D, Giese T, Scarpa A, Neoptolemos JP, Hackert T, Strobel O, Hoheisel JD, Giese NA, Bauer AS.

Pancreatology. 2015 Jul-Aug;15(4):423-31. doi: 10.1016/j.pan.2015.05.480. Epub 2015 Jun 15.


Micro RNA expression profiles in peripheral blood cells of rats that were experimentally infected with Trypanosoma congolense and different Trypanosoma brucei subspecies.

Simo G, Lueong S, Grebaut P, Guny G, Hoheisel JD.

Microbes Infect. 2015 Aug;17(8):596-608. doi: 10.1016/j.micinf.2015.03.004. Epub 2015 Mar 19.


GHSR hypermethylation: a promising pan-cancer marker.

Jandaghi P, Hoheisel JD, Riazalhosseini Y.

Cell Cycle. 2015;14(5):689-90. doi: 10.1080/15384101.2015.1006051. No abstract available.


Clinical proteomics: promises, challenges and limitations of affinity arrays.

Betzen C, Alhamdani MS, Lueong S, Schröder C, Stang A, Hoheisel JD.

Proteomics Clin Appl. 2015 Apr;9(3-4):342-7. doi: 10.1002/prca.201400156. Epub 2015 Mar 2. Review.


Highly skewed distribution of miRNAs and proteins between colorectal cancer cells and their exosomes following Cetuximab treatment: biomolecular, genetic and translational implications.

Ragusa M, Statello L, Maugeri M, Barbagallo C, Passanisi R, Alhamdani MS, Li Destri G, Cappellani A, Barbagallo D, Scalia M, Valadi H, Hoheisel JD, Di Pietro C, Purrello M.

Oncoscience. 2014 Mar 16;1(2):132-57. eCollection 2014.


GHSR DNA hypermethylation is a common epigenetic alteration of high diagnostic value in a broad spectrum of cancers.

Moskalev EA, Jandaghi P, Fallah M, Manoochehri M, Botla SK, Kolychev OV, Nikitin EA, Bubnov VV, von Knebel Doeberitz M, Strobel O, Hackert T, Büchler MW, Giese N, Bauer A, Muley T, Warth A, Schirmacher P, Haller F, Hoheisel JD, Riazalhosseini Y.

Oncotarget. 2015 Feb 28;6(6):4418-27.


Differentially regulated miRNAs as prognostic biomarkers in the blood of primary CNS lymphoma patients.

Roth P, Keller A, Hoheisel JD, Codo P, Bauer AS, Backes C, Leidinger P, Meese E, Thiel E, Korfel A, Weller M.

Eur J Cancer. 2015 Feb;51(3):382-90. doi: 10.1016/j.ejca.2014.10.028. Epub 2014 Dec 17.


Intracerebral interleukin-10 injection modulates post-ischemic neuroinflammation: an experimental microarray study.

Liesz A, Bauer A, Hoheisel JD, Veltkamp R.

Neurosci Lett. 2014 Sep 5;579:18-23. doi: 10.1016/j.neulet.2014.07.003. Epub 2014 Jul 11.


A genome-wide tethering screen reveals novel potential post-transcriptional regulators in Trypanosoma brucei.

Erben ED, Fadda A, Lueong S, Hoheisel JD, Clayton C.

PLoS Pathog. 2014 Jun 12;10(6):e1004178. doi: 10.1371/journal.ppat.1004178. eCollection 2014 Jun.


Prediction of recurrence of non muscle-invasive bladder cancer by means of a protein signature identified by antibody microarray analyses.

Srinivasan H, Allory Y, Sill M, Vordos D, Alhamdani MS, Radvanyi F, Hoheisel JD, Schröder C.

Proteomics. 2014 Jun;14(11):1333-42. doi: 10.1002/pmic.201300320. Epub 2014 Apr 29.


High throughput synthetic lethality screen reveals a tumorigenic role of adenylate cyclase in fumarate hydratase-deficient cancer cells.

Boettcher M, Lawson A, Ladenburger V, Fredebohm J, Wolf J, Hoheisel JD, Frezza C, Shlomi T.

BMC Genomics. 2014 Feb 25;15:158. doi: 10.1186/1471-2164-15-158.

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