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Items: 1 to 20 of 52

1.

NeuroRDF: semantic integration of highly curated data to prioritize biomarker candidates in Alzheimer's disease.

Iyappan A, Kawalia SB, Raschka T, Hofmann-Apitius M, Senger P.

J Biomed Semantics. 2016 Jul 8;7:45. doi: 10.1186/s13326-016-0079-8.

2.

Towards a Pathway Inventory of the Human Brain for Modeling Disease Mechanisms Underlying Neurodegeneration.

Iyappan A, Gündel M, Shahid M, Wang J, Li H, Mevissen HT, Müller B, Fluck J, Jirsa V, Domide L, Younesi E, Hofmann-Apitius M.

J Alzheimers Dis. 2016 Apr 12;52(4):1343-60. doi: 10.3233/JAD-151178.

PMID:
27079715
3.

Bioinformatics Mining and Modeling Methods for the Identification of Disease Mechanisms in Neurodegenerative Disorders.

Hofmann-Apitius M, Ball G, Gebel S, Bagewadi S, de Bono B, Schneider R, Page M, Kodamullil AT, Younesi E, Ebeling C, Tegnér J, Canard L.

Int J Mol Sci. 2015 Dec 7;16(12):29179-206. doi: 10.3390/ijms161226148. Review.

4.

Computational Modelling Approaches on Epigenetic Factors in Neurodegenerative and Autoimmune Diseases and Their Mechanistic Analysis.

Khanam Irin A, Kodamullil AT, Gündel M, Hofmann-Apitius M.

J Immunol Res. 2015;2015:737168. doi: 10.1155/2015/737168. Epub 2015 Nov 9. Review.

5.

NeuroTransDB: highly curated and structured transcriptomic metadata for neurodegenerative diseases.

Bagewadi S, Adhikari S, Dhrangadhariya A, Irin AK, Ebeling C, Namasivayam AA, Page M, Hofmann-Apitius M, Senger P.

Database (Oxford). 2015 Oct 16;2015. pii: bav099. doi: 10.1093/database/bav099. Print 2015.

6.

PDON: Parkinson's disease ontology for representation and modeling of the Parkinson's disease knowledge domain.

Younesi E, Malhotra A, Gündel M, Scordis P, Kodamullil AT, Page M, Müller B, Springstubbe S, Wüllner U, Scheller D, Hofmann-Apitius M.

Theor Biol Med Model. 2015 Sep 22;12:20. doi: 10.1186/s12976-015-0017-y.

7.

Exploring novel mechanistic insights in Alzheimer's disease by assessing reliability of protein interactions.

Malhotra A, Younesi E, Sahadevan S, Zimmermann J, Hofmann-Apitius M.

Sci Rep. 2015 Sep 8;5:13634. doi: 10.1038/srep13634.

8.

Reasoning over genetic variance information in cause-and-effect models of neurodegenerative diseases.

Naz M, Kodamullil AT, Hofmann-Apitius M.

Brief Bioinform. 2016 May;17(3):505-16. doi: 10.1093/bib/bbv063. Epub 2015 Aug 5.

9.

Construction of biological networks from unstructured information based on a semi-automated curation workflow.

Szostak J, Ansari S, Madan S, Fluck J, Talikka M, Iskandar A, De Leon H, Hofmann-Apitius M, Peitsch MC, Hoeng J.

Database (Oxford). 2015 Jun 17;2015:bav057. doi: 10.1093/database/bav057.

10.

Is dementia research ready for big data approaches?

Hofmann-Apitius M.

BMC Med. 2015 Jun 22;13:145. doi: 10.1186/s12916-015-0367-7.

11.

Identification of gene co-expression clusters in liver tissues from multiple porcine populations with high and low backfat androstenone phenotype.

Sahadevan S, Tholen E, Große-Brinkhaus C, Schellander K, Tesfaye D, Hofmann-Apitius M, Cinar MU, Gunawan A, Hölker M, Neuhoff C.

BMC Genet. 2015 Feb 28;16:21. doi: 10.1186/s12863-014-0158-8.

12.

Computable cause-and-effect models of healthy and Alzheimer's disease states and their mechanistic differential analysis.

Kodamullil AT, Younesi E, Naz M, Bagewadi S, Hofmann-Apitius M.

Alzheimers Dement. 2015 Nov;11(11):1329-39. doi: 10.1016/j.jalz.2015.02.006. Epub 2015 Apr 4.

13.

Boosting translational research on Alzheimer's disease in Europe: The Innovative Medicine Initiative AD research platform.

Vaudano E, Vannieuwenhuyse B, Van Der Geyten S, van der Lei J, Visser PJ, Streffer J, Ritchie C, McHale D, Lovestone S, Hofmann-Apitius M, Truyen L, Goldman M.

Alzheimers Dement. 2015 Sep;11(9):1121-2. doi: 10.1016/j.jalz.2015.02.002. Epub 2015 Apr 7. No abstract available.

PMID:
25754460
14.

Knowledge retrieval from PubMed abstracts and electronic medical records with the Multiple Sclerosis Ontology.

Malhotra A, Gündel M, Rajput AM, Mevissen HT, Saiz A, Pastor X, Lozano-Rubi R, Martinez-Lapiscina EH, Zubizarreta I, Mueller B, Kotelnikova E, Toldo L, Hofmann-Apitius M, Villoslada P.

PLoS One. 2015 Feb 9;10(2):e0116718. doi: 10.1371/journal.pone.0116718. eCollection 2015. Erratum in: PLoS One. 2015;10(3):e0122614. Martinez-Lapsicina, Elena H [corrected to Martinez-Lapiscina, Elena H].

15.

Towards the taxonomy of human disease.

Hofmann-Apitius M, Alarcón-Riquelme ME, Chamberlain C, McHale D.

Nat Rev Drug Discov. 2015 Feb;14(2):75-6. doi: 10.1038/nrd4537. Review.

PMID:
25633780
16.

Systems approach for the selection of micro-RNAs as therapeutic biomarkers of anti-EGFR monoclonal antibody treatment in colorectal cancer.

Deyati A, Bagewadi S, Senger P, Hofmann-Apitius M, Novac N.

Sci Rep. 2015 Jan 27;5:8013. doi: 10.1038/srep08013.

17.

Linking hypothetical knowledge patterns to disease molecular signatures for biomarker discovery in Alzheimer's disease.

Malhotra A, Younesi E, Bagewadi S, Hofmann-Apitius M.

Genome Med. 2014 Dec 3;6(11):97. doi: 10.1186/s13073-014-0097-z. eCollection 2014.

18.

CSEO - the Cigarette Smoke Exposure Ontology.

Younesi E, Ansari S, Guendel M, Ahmadi S, Coggins C, Hoeng J, Hofmann-Apitius M, Peitsch MC.

J Biomed Semantics. 2014 Jul 10;5:31. doi: 10.1186/2041-1480-5-31. eCollection 2014.

19.

Pathway based analysis of genes and interactions influencing porcine testis samples from boars with divergent androstenone content in back fat.

Sahadevan S, Gunawan A, Tholen E, Große-Brinkhaus C, Tesfaye D, Schellander K, Hofmann-Apitius M, Cinar MU, Uddin MJ.

PLoS One. 2014 Mar 10;9(3):e91077. doi: 10.1371/journal.pone.0091077. eCollection 2014.

20.

Detecting miRNA Mentions and Relations in Biomedical Literature.

Bagewadi S, Bobić T, Hofmann-Apitius M, Fluck J, Klinger R.

Version 3. F1000Res. 2014 Aug 28 [revised 2015 Oct 1];3:205. doi: 10.12688/f1000research.4591.3. eCollection 2014.

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