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Results: 1 to 20 of 72

1.

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

Eccles SA, Aboagye EO, Ali S, Anderson AS, Armes J, Berditchevski F, Blaydes JP, Brennan K, Brown NJ, Bryant HE, Bundred NJ, Burchell JM, Campbell AM, Carroll JS, Clarke RB, Coles CE, Cook GJ, Cox A, Curtin NJ, Dekker LV, Silva Idos S, Duffy SW, Easton DF, Eccles DM, Edwards DR, Edwards J, Evans D, Fenlon DF, Flanagan JM, Foster C, Gallagher WM, Garcia-Closas M, Gee JM, Gescher AJ, Goh V, Groves AM, Harvey AJ, Harvie M, Hennessy BT, Hiscox S, Holen I, Howell SJ, Howell A, Hubbard G, Hulbert-Williams N, Hunter MS, Jasani B, Jones LJ, Key TJ, Kirwan CC, Kong A, Kunkler IH, Langdon SP, Leach MO, Mann DJ, Marshall JF, Martin L, Martin SG, Macdougall JE, Miles DW, Miller WR, Morris JR, Moss SM, Mullan P, Natrajan R, O'Connor JP, O'Connor R, Palmieri C, Pharoah PD, Rakha EA, Reed E, Robinson SP, Sahai E, Saxton JM, Schmid P, Smalley MJ, Speirs V, Stein R, Stingl J, Streuli CH, Tutt AN, Velikova G, Walker RA, Watson CJ, Williams KJ, Young LS, Thompson AM.

Breast Cancer Res. 2013 Oct 1;15(5):R92. doi: 10.1186/bcr3493. Review.

PMID:
24286369
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A mechanism for epithelial-mesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3).

Hogstrand C, Kille P, Ackland ML, Hiscox S, Taylor KM.

Biochem J. 2013 Oct 15;455(2):229-37. doi: 10.1042/BJ20130483.

PMID:
23919497
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Targeting focal adhesion kinase in ER+/HER2+ breast cancer improves trastuzumab response.

Lazaro G, Smith C, Goddard L, Jordan N, McClelland R, Barrett-Lee P, Nicholson RI, Hiscox S.

Endocr Relat Cancer. 2013 Aug 28;20(5):691-704. doi: 10.1530/ERC-13-0019. Print 2013 Oct.

PMID:
23900794
[PubMed - indexed for MEDLINE]
4.

Pro-metastatic tumor-stroma interactions in breast cancer.

Gangadhara S, Barrett-Lee P, Nicholson RI, Hiscox S.

Future Oncol. 2012 Nov;8(11):1427-42. doi: 10.2217/fon.12.134. Review.

PMID:
23148616
[PubMed - indexed for MEDLINE]
5.

Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan.

Hiscox S, Baruha B, Smith C, Bellerby R, Goddard L, Jordan N, Poghosyan Z, Nicholson RI, Barrett-Lee P, Gee J.

BMC Cancer. 2012 Oct 6;12:458. doi: 10.1186/1471-2407-12-458.

PMID:
23039365
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Protein kinase CK2 triggers cytosolic zinc signaling pathways by phosphorylation of zinc channel ZIP7.

Taylor KM, Hiscox S, Nicholson RI, Hogstrand C, Kille P.

Sci Signal. 2012 Feb 7;5(210):ra11. doi: 10.1126/scisignal.2002585.

PMID:
22317921
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Therapeutic targeting of tumor-stroma interactions.

Hiscox S, Barrett-Lee P, Nicholson RI.

Expert Opin Ther Targets. 2011 May;15(5):609-21. doi: 10.1517/14728222.2011.561201. Epub 2011 Mar 10. Review.

PMID:
21388336
[PubMed - indexed for MEDLINE]
8.

Acquired endocrine resistance in breast cancer: implications for tumour metastasis.

Hayes E, Nicholson RI, Hiscox S.

Front Biosci (Landmark Ed). 2011 Jan 1;16:838-48. Review.

PMID:
21196206
[PubMed - indexed for MEDLINE]
9.

New therapeutic approaches in breast cancer.

Davies E, Hiscox S.

Maturitas. 2011 Feb;68(2):121-8. doi: 10.1016/j.maturitas.2010.10.012. Epub 2010 Dec 8. Review.

PMID:
21144683
[PubMed - indexed for MEDLINE]
10.

Zip4 (Slc39a4) expression is activated in hepatocellular carcinomas and functions to repress apoptosis, enhance cell cycle and increase migration.

Weaver BP, Zhang Y, Hiscox S, Guo GL, Apte U, Taylor KM, Sheline CT, Wang L, Andrews GK.

PLoS One. 2010 Oct 4;5(10). pii: e13158. doi: 10.1371/journal.pone.0013158.

PMID:
20957146
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Src-mediated regulation of homotypic cell adhesion: implications for cancer progression and opportunities for therapeutic intervention.

Wadhawan A, Smith C, Nicholson RI, Barrett-Lee P, Hiscox S.

Cancer Treat Rev. 2011 May;37(3):234-41. doi: 10.1016/j.ctrv.2010.08.003. Review.

PMID:
20888696
[PubMed - indexed for MEDLINE]
12.

Combining Src inhibitors and aromatase inhibitors: a novel strategy for overcoming endocrine resistance and bone loss.

Hiscox S, Barrett-Lee P, Borley AC, Nicholson RI.

Eur J Cancer. 2010 Aug;46(12):2187-95. doi: 10.1016/j.ejca.2010.04.012. Epub 2010 May 13. Review.

PMID:
20471823
[PubMed - indexed for MEDLINE]
13.

Inhibition of focal adhesion kinase suppresses the adverse phenotype of endocrine-resistant breast cancer cells and improves endocrine response in endocrine-sensitive cells.

Hiscox S, Barnfather P, Hayes E, Bramble P, Christensen J, Nicholson RI, Barrett-Lee P.

Breast Cancer Res Treat. 2011 Feb;125(3):659-69. doi: 10.1007/s10549-010-0857-4. Epub 2010 Mar 31.

PMID:
20354780
[PubMed - indexed for MEDLINE]
14.

Elevated Src kinase activity attenuates Tamoxifen response in vitro and is associated with poor prognosis clinically.

Morgan L, Gee J, Pumford S, Farrow L, Finlay P, Robertson J, Ellis I, Kawakatsu H, Nicholson R, Hiscox S.

Cancer Biol Ther. 2009 Aug;8(16):1550-8.

PMID:
19830888
[PubMed - indexed for MEDLINE]
Free Article
15.

Aromatase inhibitors in breast cancer.

Hiscox S, Davies EL, Barrett-Lee P.

Maturitas. 2009 Aug 20;63(4):275-9. doi: 10.1016/j.maturitas.2009.05.008. Epub 2009 Jul 3. Review.

PMID:
19577386
[PubMed - indexed for MEDLINE]
16.

SRC as a therapeutic target in breast cancer.

Morgan L, Nicholson RI, Hiscox S.

Endocr Metab Immune Disord Drug Targets. 2008 Dec;8(4):273-8. Review.

PMID:
19075780
[PubMed - indexed for MEDLINE]
17.

Anti-oestrogens but not oestrogen deprivation promote cellular invasion in intercellular adhesion-deficient breast cancer cells.

Borley AC, Hiscox S, Gee J, Smith C, Shaw V, Barrett-Lee P, Nicholson RI.

Breast Cancer Res. 2008;10(6):R103. doi: 10.1186/bcr2206. Epub 2008 Dec 4.

PMID:
19055788
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

ZIP7-mediated intracellular zinc transport contributes to aberrant growth factor signaling in antihormone-resistant breast cancer Cells.

Taylor KM, Vichova P, Jordan N, Hiscox S, Hendley R, Nicholson RI.

Endocrinology. 2008 Oct;149(10):4912-20. doi: 10.1210/en.2008-0351. Epub 2008 Jun 26.

PMID:
18583420
[PubMed - indexed for MEDLINE]
19.

Dual targeting of Src and ER prevents acquired antihormone resistance in breast cancer cells.

Hiscox S, Jordan NJ, Smith C, James M, Morgan L, Taylor KM, Green TP, Nicholson RI.

Breast Cancer Res Treat. 2009 May;115(1):57-67. doi: 10.1007/s10549-008-0058-6. Epub 2008 May 21.

PMID:
18493848
[PubMed - indexed for MEDLINE]
20.

Src inhibitors in breast cancer therapy.

Hiscox S, Nicholson RI.

Expert Opin Ther Targets. 2008 Jun;12(6):757-67. doi: 10.1517/14728222.12.6.757 . Review.

PMID:
18479222
[PubMed - indexed for MEDLINE]

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