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Results: 1 to 20 of 165

1.

MCL1 and BCL-xL levels in solid tumors are predictive of dinaciclib-induced apoptosis.

Booher RN, Hatch H, Dolinski BM, Nguyen T, Harmonay L, Al-Assaad AS, Ayers M, Nebozhyn M, Loboda A, Hirsch HA, Zhang T, Shi B, Merkel CE, Angagaw MH, Wang Y, Long BJ, Lennon XQ, Miselis N, Pucci V, Monahan JW, Lee J, Kondic AG, Im EK, Mauro D, Blanchard R, Gilliland G, Fawell SE, Zawel L, Schuller AG, Strack P.

PLoS One. 2014 Oct 7;9(10):e108371. doi: 10.1371/journal.pone.0108371. eCollection 2014.

PMID:
25289887
[PubMed - in process]
Free PMC Article
2.

Preclinical evaluation of the WEE1 inhibitor MK-1775 as single-agent anticancer therapy.

Guertin AD, Li J, Liu Y, Hurd MS, Schuller AG, Long B, Hirsch HA, Feldman I, Benita Y, Toniatti C, Zawel L, Fawell SE, Gilliland DG, Shumway SD.

Mol Cancer Ther. 2013 Aug;12(8):1442-52. doi: 10.1158/1535-7163.MCT-13-0025. Epub 2013 May 22.

PMID:
23699655
[PubMed - indexed for MEDLINE]
Free Article
3.

Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth.

Hirsch HA, Iliopoulos D, Struhl K.

Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):972-7. doi: 10.1073/pnas.1221055110. Epub 2012 Dec 31.

PMID:
23277563
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types.

Iliopoulos D, Hirsch HA, Struhl K.

Cancer Res. 2011 May 1;71(9):3196-201. doi: 10.1158/0008-5472.CAN-10-3471. Epub 2011 Mar 17.

PMID:
21415163
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion.

Iliopoulos D, Hirsch HA, Wang G, Struhl K.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1397-402. doi: 10.1073/pnas.1018898108. Epub 2011 Jan 10.

PMID:
21220315
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells.

Iliopoulos D, Lindahl-Allen M, Polytarchou C, Hirsch HA, Tsichlis PN, Struhl K.

Mol Cell. 2010 Sep 10;39(5):761-72. doi: 10.1016/j.molcel.2010.08.013.

PMID:
20832727
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer.

Iliopoulos D, Jaeger SA, Hirsch HA, Bulyk ML, Struhl K.

Mol Cell. 2010 Aug 27;39(4):493-506. doi: 10.1016/j.molcel.2010.07.023.

PMID:
20797623
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases.

Hirsch HA, Iliopoulos D, Joshi A, Zhang Y, Jaeger SA, Bulyk M, Tsichlis PN, Shirley Liu X, Struhl K.

Cancer Cell. 2010 Apr 13;17(4):348-61. doi: 10.1016/j.ccr.2010.01.022.

PMID:
20385360
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation.

Iliopoulos D, Hirsch HA, Struhl K.

Cell. 2009 Nov 13;139(4):693-706. doi: 10.1016/j.cell.2009.10.014. Epub 2009 Oct 29.

PMID:
19878981
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission.

Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K.

Cancer Res. 2009 Oct 1;69(19):7507-11. doi: 10.1158/0008-5472.CAN-09-2994. Epub 2009 Sep 14. Erratum in: Cancer Res. 2009 Nov 15;69(22):8832.

PMID:
19752085
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Differential analysis for high density tiling microarray data.

Ghosh S, Hirsch HA, Sekinger EA, Kapranov P, Struhl K, Gingeras TR.

BMC Bioinformatics. 2007 Sep 24;8:359.

PMID:
17892592
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

ENCODE Project Consortium, Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S, Koch CM, Asthana S, Malhotra A, Adzhubei I, Greenbaum JA, Andrews RM, Flicek P, Boyle PJ, Cao H, Carter NP, Clelland GK, Davis S, Day N, Dhami P, Dillon SC, Dorschner MO, Fiegler H, Giresi PG, Goldy J, Hawrylycz M, Haydock A, Humbert R, James KD, Johnson BE, Johnson EM, Frum TT, Rosenzweig ER, Karnani N, Lee K, Lefebvre GC, Navas PA, Neri F, Parker SC, Sabo PJ, Sandstrom R, Shafer A, Vetrie D, Weaver M, Wilcox S, Yu M, Collins FS, Dekker J, Lieb JD, Tullius TD, Crawford GE, Sunyaev S, Noble WS, Dunham I, Denoeud F, Reymond A, Kapranov P, Rozowsky J, Zheng D, Castelo R, Frankish A, Harrow J, Ghosh S, Sandelin A, Hofacker IL, Baertsch R, Keefe D, Dike S, Cheng J, Hirsch HA, Sekinger EA, Lagarde J, Abril JF, Shahab A, Flamm C, Fried C, Hackermüller J, Hertel J, Lindemeyer M, Missal K, Tanzer A, Washietl S, Korbel J, Emanuelsson O, Pedersen JS, Holroyd N, Taylor R, Swarbreck D, Matthews N, Dickson MC, Thomas DJ, Weirauch MT, Gilbert J, Drenkow J, Bell I, Zhao X, Srinivasan KG, Sung WK, Ooi HS, Chiu KP, Foissac S, Alioto T, Brent M, Pachter L, Tress ML, Valencia A, Choo SW, Choo CY, Ucla C, Manzano C, Wyss C, Cheung E, Clark TG, Brown JB, Ganesh M, Patel S, Tammana H, Chrast J, Henrichsen CN, Kai C, Kawai J, Nagalakshmi U, Wu J, Lian Z, Lian J, Newburger P, Zhang X, Bickel P, Mattick JS, Carninci P, Hayashizaki Y, Weissman S, Hubbard T, Myers RM, Rogers J, Stadler PF, Lowe TM, Wei CL, Ruan Y, Struhl K, Gerstein M, Antonarakis SE, Fu Y, Green ED, Karaöz U, Siepel A, Taylor J, Liefer LA, Wetterstrand KA, Good PJ, Feingold EA, Guyer MS, Cooper GM, Asimenos G, Dewey CN, Hou M, Nikolaev S, Montoya-Burgos JI, Löytynoja A, Whelan S, Pardi F, Massingham T, Huang H, Zhang NR, Holmes I, Mullikin JC, Ureta-Vidal A, Paten B, Seringhaus M, Church D, Rosenbloom K, Kent WJ, Stone EA; NISC Comparative Sequencing Program; Baylor College of Medicine Human Genome Sequencing Center; Washington University Genome Sequencing Center; Broad Institute; Children's Hospital Oakland Research Institute, Batzoglou S, Goldman N, Hardison RC, Haussler D, Miller W, Sidow A, Trinklein ND, Zhang ZD, Barrera L, Stuart R, King DC, Ameur A, Enroth S, Bieda MC, Kim J, Bhinge AA, Jiang N, Liu J, Yao F, Vega VB, Lee CW, Ng P, Shahab A, Yang A, Moqtaderi Z, Zhu Z, Xu X, Squazzo S, Oberley MJ, Inman D, Singer MA, Richmond TA, Munn KJ, Rada-Iglesias A, Wallerman O, Komorowski J, Fowler JC, Couttet P, Bruce AW, Dovey OM, Ellis PD, Langford CF, Nix DA, Euskirchen G, Hartman S, Urban AE, Kraus P, Van Calcar S, Heintzman N, Kim TH, Wang K, Qu C, Hon G, Luna R, Glass CK, Rosenfeld MG, Aldred SF, Cooper SJ, Halees A, Lin JM, Shulha HP, Zhang X, Xu M, Haidar JN, Yu Y, Ruan Y, Iyer VR, Green RD, Wadelius C, Farnham PJ, Ren B, Harte RA, Hinrichs AS, Trumbower H, Clawson H, Hillman-Jackson J, Zweig AS, Smith K, Thakkapallayil A, Barber G, Kuhn RM, Karolchik D, Armengol L, Bird CP, de Bakker PI, Kern AD, Lopez-Bigas N, Martin JD, Stranger BE, Woodroffe A, Davydov E, Dimas A, Eyras E, Hallgrímsdóttir IB, Huppert J, Zody MC, Abecasis GR, Estivill X, Bouffard GG, Guan X, Hansen NF, Idol JR, Maduro VV, Maskeri B, McDowell JC, Park M, Thomas PJ, Young AC, Blakesley RW, Muzny DM, Sodergren E, Wheeler DA, Worley KC, Jiang H, Weinstock GM, Gibbs RA, Graves T, Fulton R, Mardis ER, Wilson RK, Clamp M, Cuff J, Gnerre S, Jaffe DB, Chang JL, Lindblad-Toh K, Lander ES, Koriabine M, Nefedov M, Osoegawa K, Yoshinaga Y, Zhu B, de Jong PJ.

Nature. 2007 Jun 14;447(7146):799-816.

PMID:
17571346
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments.

Ghosh S, Hirsch HA, Sekinger E, Struhl K, Gingeras TR.

BMC Bioinformatics. 2006 Oct 5;7:434.

PMID:
17022824
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Distinct mechanisms for repression of RNA polymerase III transcription by the retinoblastoma tumor suppressor protein.

Hirsch HA, Jawdekar GW, Lee KA, Gu L, Henry RW.

Mol Cell Biol. 2004 Jul;24(13):5989-99.

PMID:
15199152
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition.

Hinkley CS, Hirsch HA, Gu L, LaMere B, Henry RW.

J Biol Chem. 2003 May 16;278(20):18649-57. Epub 2003 Mar 5.

PMID:
12621023
[PubMed - indexed for MEDLINE]
Free Article
16.
17.

[Treatment of vaginal discharge].

Hirsch HA.

Dtsch Med Wochenschr. 1997 Apr 18;122(16):513-6. Review. German. No abstract available.

PMID:
9162625
[PubMed - indexed for MEDLINE]
18.

[Rational diagnosis of vaginal discharge].

Hirsch HA.

Dtsch Med Wochenschr. 1997 Apr 11;122(15):477-80. Review. German. No abstract available.

PMID:
9147939
[PubMed - indexed for MEDLINE]
19.

[Episiotomy and its complications].

Hirsch HA.

Z Geburtshilfe Neonatol. 1997;201 Suppl 1:55-62. Review. German.

PMID:
9410530
[PubMed - indexed for MEDLINE]
20.

[Pelvic floor reconstruction after traumatic childbirth damage].

Franz HB, Hirsch HA.

Zentralbl Chir. 1996;121(8):688-91. Review. German.

PMID:
8967217
[PubMed - indexed for MEDLINE]

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