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Results: 1 to 20 of 104

1.

Sensitive detection of chromatin-altering polymorphisms reveals autoimmune disease mechanisms.

Del Rosario RC, Poschmann J, Rouam SL, Png E, Khor CC, Hibberd ML, Prabhakar S.

Nat Methods. 2015 Mar 23. doi: 10.1038/nmeth.3326. [Epub ahead of print]

PMID:
25799442
2.

New loci and coding variants confer risk for age-related macular degeneration in East Asians.

Cheng CY, Yamashiro K, Chen LJ, Ahn J, Huang L, Huang L, Cheung CM, Miyake M, Cackett PD, Yeo IY, Laude A, Mathur R, Pang J, Sim KS, Koh AH, Chen P, Lee SY, Wong D, Chan CM, Loh BK, Sun Y, Davila S, Nakata I, Nakanishi H, Akagi-Kurashige Y, Gotoh N, Tsujikawa A, Matsuda F, Mori K, Yoneya S, Sakurada Y, Iijima H, Iida T, Honda S, Lai TY, Tam PO, Chen H, Tang S, Ding X, Wen F, Lu F, Zhang X, Shi Y, Zhao P, Zhao B, Sang J, Gong B, Dorajoo R, Yuan JM, Koh WP, van Dam RM, Friedlander Y, Lin Y, Hibberd ML, Foo JN, Wang N, Wong CH, Tan GS, Park SJ, Bhargava M, Gopal L, Naing T, Liao J, Ong PG, Mitchell P, Zhou P, Xie X, Liang J, Mei J, Jin X, Saw SM, Ozaki M, Mizoguchi T, Kurimoto Y, Woo SJ, Chung H, Yu HG, Shin JY, Park DH, Kim IT, Chang W, Sagong M, Lee SJ, Kim HW, Lee JE, Li Y, Liu J, Teo YY, Heng CK, Lim TH, Yang SK, Song K, Vithana EN, Aung T, Bei JX, Zeng YX, Tai ES, Li XX, Yang Z, Park KH, Pang CP, Yoshimura N, Wong TY, Khor CC.

Nat Commun. 2015 Jan 28;6:6063. doi: 10.1038/ncomms7063.

3.

Global gene expression profiling identifies new therapeutic targets in acute Kawasaki disease.

Hoang LT, Shimizu C, Ling L, Naim AN, Khor CC, Tremoulet AH, Wright V, Levin M, Hibberd ML, Burns JC.

Genome Med. 2014 Nov 20;6(11):541. doi: 10.1186/s13073-014-0102-6. eCollection 2014.

4.

BAsE-Seq: a method for obtaining long viral haplotypes from short sequence reads.

Hong LZ, Hong S, Wong HT, Aw PP, Cheng Y, Wilm A, de Sessions PF, Lim SG, Nagarajan N, Hibberd ML, Quake SR, Burkholder WF.

Genome Biol. 2014;15(11):517.

5.

Variation at HLA-DRB1 is associated with resistance to enteric fever.

Dunstan SJ, Hue NT, Han B, Li Z, Tram TT, Sim KS, Parry CM, Chinh NT, Vinh H, Lan NP, Thieu NT, Vinh PV, Koirala S, Dongol S, Arjyal A, Karkey A, Shilpakar O, Dolecek C, Foo JN, Phuong le T, Lanh MN, Do T, Aung T, Hon do N, Teo YY, Hibberd ML, Anders KL, Okada Y, Raychaudhuri S, Simmons CP, Baker S, de Bakker PI, Basnyat B, Hien TT, Farrar JJ, Khor CC.

Nat Genet. 2014 Dec;46(12):1333-6. doi: 10.1038/ng.3143. Epub 2014 Nov 10.

PMID:
25383971
6.

Patient-based transcriptome-wide analysis identify interferon and ubiquination pathways as potential predictors of influenza A disease severity.

Hoang LT, Tolfvenstam T, Ooi EE, Khor CC, Naim AN, Ho EX, Ong SH, Wertheim HF, Fox A, Van Vinh Nguyen C, Nghiem NM, Ha TM, Thi Ngoc Tran A, Tambayah P, Lin R, Sangsajja C, Manosuthi W, Chuchottaworn C, Sansayunh P, Chotpitayasunondh T, Suntarattiwong P, Chokephaibulkit K, Puthavathana P, de Jong MD, Farrar J, van Doorn HR, Hibberd ML.

PLoS One. 2014 Nov 3;9(11):e111640. doi: 10.1371/journal.pone.0111640. eCollection 2014.

7.

cnvCapSeq: detecting copy number variation in long-range targeted resequencing data.

Bellos E, Kumar V, Lin C, Maggi J, Phua ZY, Cheng CY, Cheung CM, Hibberd ML, Wong TY, Coin LJ, Davila S.

Nucleic Acids Res. 2014 Nov 10;42(20):e158. doi: 10.1093/nar/gku849. Epub 2014 Sep 16.

8.

Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial.

Low JG, Sung C, Wijaya L, Wei Y, Rathore AP, Watanabe S, Tan BH, Toh L, Chua LT, Hou Y, Chow A, Howe S, Chan WK, Tan KH, Chung JS, Cherng BP, Lye DC, Tambayah PA, Ng LC, Connolly J, Hibberd ML, Leo YS, Cheung YB, Ooi EE, Vasudevan SG.

Lancet Infect Dis. 2014 Aug;14(8):706-15. doi: 10.1016/S1473-3099(14)70730-3. Epub 2014 May 28.

PMID:
24877997
9.

Enterococcus faecalis from healthy infants modulates inflammation through MAPK signaling pathways.

Wang S, Hibberd ML, Pettersson S, Lee YK.

PLoS One. 2014 May 15;9(5):e97523. doi: 10.1371/journal.pone.0097523. eCollection 2014.

10.

Diagnosis of childhood tuberculosis and host RNA expression in Africa.

Anderson ST, Kaforou M, Brent AJ, Wright VJ, Banwell CM, Chagaluka G, Crampin AC, Dockrell HM, French N, Hamilton MS, Hibberd ML, Kern F, Langford PR, Ling L, Mlotha R, Ottenhoff TH, Pienaar S, Pillay V, Scott JA, Twahir H, Wilkinson RJ, Coin LJ, Heyderman RS, Levin M, Eley B; ILULU Consortium; KIDS TB Study Group.

N Engl J Med. 2014 May 1;370(18):1712-23. doi: 10.1056/NEJMoa1303657.

11.

Next-generation whole genome sequencing of dengue virus.

Aw PP, de Sessions PF, Wilm A, Hoang LT, Nagarajan N, Sessions OM, Hibberd ML.

Methods Mol Biol. 2014;1138:175-95. doi: 10.1007/978-1-4939-0348-1_12.

PMID:
24696338
12.

Leukocyte immunoglobulin-like receptor B1 is critical for antibody-dependent dengue.

Chan KR, Ong EZ, Tan HC, Zhang SL, Zhang Q, Tang KF, Kaliaperumal N, Lim AP, Hibberd ML, Chan SH, Connolly JE, Krishnan MN, Lok SM, Hanson BJ, Lin CN, Ooi EE.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2722-7. doi: 10.1073/pnas.1317454111. Epub 2014 Jan 13.

13.

Corticosteroids for dengue - why don't they work?

Nguyen TH, Nguyen TH, Vu TT, Farrar J, Hoang TL, Dong TH, Ngoc Tran V, Phung KL, Wolbers M, Whitehead SS, Hibberd ML, Wills B, Simmons CP.

PLoS Negl Trop Dis. 2013 Dec 12;7(12):e2592. doi: 10.1371/journal.pntd.0002592. eCollection 2013.

14.

Treatment response in Kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G.

Ogata S, Shimizu C, Franco A, Touma R, Kanegaye JT, Choudhury BP, Naidu NN, Kanda Y, Hoang LT, Hibberd ML, Tremoulet AH, Varki A, Burns JC.

PLoS One. 2013 Dec 6;8(12):e81448. doi: 10.1371/journal.pone.0081448. eCollection 2013.

15.

Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study.

Kaforou M, Wright VJ, Oni T, French N, Anderson ST, Bangani N, Banwell CM, Brent AJ, Crampin AC, Dockrell HM, Eley B, Heyderman RS, Hibberd ML, Kern F, Langford PR, Ling L, Mendelson M, Ottenhoff TH, Zgambo F, Wilkinson RJ, Coin LJ, Levin M.

PLoS Med. 2013 Oct;10(10):e1001538. doi: 10.1371/journal.pmed.1001538. Epub 2013 Oct 22.

16.

Transcriptome signatures in Helicobacter pylori-infected mucosa identifies acidic mammalian chitinase loss as a corpus atrophy marker.

Nookaew I, Thorell K, Worah K, Wang S, Hibberd ML, Sjövall H, Pettersson S, Nielsen J, Lundin SB.

BMC Med Genomics. 2013 Oct 11;6:41. doi: 10.1186/1755-8794-6-41.

17.

Replication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility.

Chang CJ, Kuo HC, Chang JS, Lee JK, Tsai FJ, Khor CC, Chang LC, Chen SP, Ko TM, Liu YM, Chen YJ, Hong YM, Jang GY, Hibberd ML, Kuijpers T, Burgner D, Levin M, Burns JC, Davila S; International Kawasaki Disease Genetics Consortium; Korean Kawasaki Disease Genetics Consortium; Taiwan Kawasaki Disease Genetics Consortium, Chen YT, Chen CH, Wu JY, Lee YC.

PLoS One. 2013 Aug 30;8(8):e72037. doi: 10.1371/journal.pone.0072037. eCollection 2013.

18.

Reduction of HBV replication prolongs the early immunological response to IFNα therapy.

Tan AT, Hoang LT, Chin D, Rasmussen E, Lopatin U, Hart S, Bitter H, Chu T, Gruenbaum L, Ravindran P, Zhong H, Gane E, Lim SG, Chow WC, Chen PJ, Petric R, Bertoletti A, Hibberd ML.

J Hepatol. 2014 Jan;60(1):54-61. doi: 10.1016/j.jhep.2013.08.020. Epub 2013 Aug 29.

PMID:
23994382
19.

Inhibition of megakaryocyte development in the bone marrow underlies dengue virus-induced thrombocytopenia in humanized mice.

Sridharan A, Chen Q, Tang KF, Ooi EE, Hibberd ML, Chen J.

J Virol. 2013 Nov;87(21):11648-58. doi: 10.1128/JVI.01156-13. Epub 2013 Aug 21.

20.

Exploring the mode of action of bioactive compounds by microfluidic transcriptional profiling in mycobacteria.

Murima P, de Sessions PF, Lim V, Naim AN, Bifani P, Boshoff HI, Sambandamurthy VK, Dick T, Hibberd ML, Schreiber M, Rao SP.

PLoS One. 2013 Jul 31;8(7):e69191. doi: 10.1371/journal.pone.0069191. Print 2013.

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