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Results: 1 to 20 of 106

1.

ER proteostasis disturbances in Parkinson's disease: novel insights.

Mercado G, Castillo V, Vidal R, Hetz C.

Front Aging Neurosci. 2015 Mar 27;7:39. doi: 10.3389/fnagi.2015.00039. eCollection 2015. No abstract available.

2.

RNA metabolism: putting the brake on the UPR.

Carreras-Sureda A, Hetz C.

EMBO Rep. 2015 Mar 25. pii: e201540227. [Epub ahead of print] No abstract available.

PMID:
25807987
3.

ER stress signaling and neurodegeneration: At the intersection between Alzheimer's disease and Prion-related disorders.

Torres M, Matamala JM, Duran-Aniotz C, Cornejo VH, Foley A, Hetz C.

Virus Res. 2014 Dec 31. pii: S0168-1702(14)00523-1. doi: 10.1016/j.virusres.2014.12.018. [Epub ahead of print]

PMID:
25556124
4.

Autophagy meets fused in sarcoma-positive stress granules.

Matus S, Bosco DA, Hetz C.

Neurobiol Aging. 2014 Dec;35(12):2832-5. doi: 10.1016/j.neurobiolaging.2014.08.019. Epub 2014 Sep 28.

PMID:
25444610
5.

Protein homeostasis: Modeling UPR adaptive responses.

Medinas DB, Hetz C.

Nat Chem Biol. 2014 Nov;10(11):879-80. doi: 10.1038/nchembio.1653. No abstract available.

PMID:
25325696
6.

Targeting autophagy in neurodegenerative diseases.

Vidal RL, Matus S, Bargsted L, Hetz C.

Trends Pharmacol Sci. 2014 Nov;35(11):583-91. doi: 10.1016/j.tips.2014.09.002. Epub 2014 Sep 27. Review.

PMID:
25270767
7.

RESETing ER proteostasis: selective stress pathway hidden in the secretory route.

Couve A, Hetz C.

EMBO J. 2014 Nov 3;33(21):2444-6. doi: 10.15252/embj.201489845. Epub 2014 Sep 4. Review. No abstract available.

PMID:
25190517
8.

Cell-nonautonomous control of the UPR: mastering energy homeostasis.

Mardones P, Dillin A, Hetz C.

Cell Metab. 2014 Sep 2;20(3):385-7. doi: 10.1016/j.cmet.2014.07.009.

PMID:
25185942
9.

Control of systemic proteostasis by the nervous system.

Mardones P, Martínez G, Hetz C.

Trends Cell Biol. 2015 Jan;25(1):1-10. doi: 10.1016/j.tcb.2014.08.001. Epub 2014 Aug 28.

PMID:
25174273
10.

Cellular mechanisms of endoplasmic reticulum stress signaling in health and disease. 1. An overview.

Dufey E, Sepúlveda D, Rojas-Rivera D, Hetz C.

Am J Physiol Cell Physiol. 2014 Oct 1;307(7):C582-94. doi: 10.1152/ajpcell.00258.2014. Epub 2014 Aug 20. Review.

PMID:
25143348
11.

Interplay between the oxidoreductase PDIA6 and microRNA-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis.

Groenendyk J, Peng Z, Dudek E, Fan X, Mizianty MJ, Dufey E, Urra H, Sepulveda D, Rojas-Rivera D, Lim Y, Kim do H, Baretta K, Srikanth S, Gwack Y, Ahnn J, Kaufman RJ, Lee SK, Hetz C, Kurgan L, Michalak M.

Sci Signal. 2014 Jun 10;7(329):ra54. doi: 10.1126/scisignal.2004983.

PMID:
24917591
12.

Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis.

Nassif M, Valenzuela V, Rojas-Rivera D, Vidal R, Matus S, Castillo K, Fuentealba Y, Kroemer G, Levine B, Hetz C.

Autophagy. 2014 Jul;10(7):1256-71. doi: 10.4161/auto.28784. Epub 2014 May 12.

PMID:
24905722
13.

Common ground: stem cell approaches find shared pathways underlying ALS.

Matus S, Medinas DB, Hetz C.

Cell Stem Cell. 2014 Jun 5;14(6):697-9. doi: 10.1016/j.stem.2014.05.001.

PMID:
24905158
14.

A novel ER stress-independent function of the UPR in angiogenesis.

Urra H, Hetz C.

Mol Cell. 2014 May 22;54(4):542-4. doi: 10.1016/j.molcel.2014.05.013.

PMID:
24856218
15.

Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1.

Valdés P, Mercado G, Vidal RL, Molina C, Parsons G, Court FA, Martinez A, Galleguillos D, Armentano D, Schneider BL, Hetz C.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6804-9. doi: 10.1073/pnas.1321845111. Epub 2014 Apr 21.

16.

The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity.

Campos G, Schmidt-Heck W, Ghallab A, Rochlitz K, Pütter L, Medinas DB, Hetz C, Widera A, Cadenas C, Begher-Tibbe B, Reif R, Günther G, Sachinidis A, Hengstler JG, Godoy P.

Arch Toxicol. 2014 Jun;88(6):1267-80. doi: 10.1007/s00204-014-1240-8. Epub 2014 Apr 20.

PMID:
24748426
17.

A new method to measure autophagy flux in the nervous system.

Matus S, Valenzuela V, Hetz C.

Autophagy. 2014 Apr;10(4):710-4. doi: 10.4161/auto.28434. Epub 2014 Mar 17.

18.

Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases.

Hetz C, Mollereau B.

Nat Rev Neurosci. 2014 Apr;15(4):233-49. doi: 10.1038/nrn3689. Epub 2014 Mar 12. Review.

PMID:
24619348
19.

TMBIM protein family: ancestral regulators of cell death.

Rojas-Rivera D, Hetz C.

Oncogene. 2015 Jan 15;34(3):269-80. doi: 10.1038/onc.2014.6. Epub 2014 Feb 24.

PMID:
24561528
20.

Memory loss in Alzheimer's disease: are the alterations in the UPR network involved in the cognitive impairment?

Duran-Aniotz C, Martínez G, Hetz C.

Front Aging Neurosci. 2014 Jan 30;6:8. doi: 10.3389/fnagi.2014.00008. eCollection 2014. No abstract available.

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