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Results: 1 to 20 of 96

1.

Interplay between the oxidoreductase PDIA6 and microRNA-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis.

Groenendyk J, Peng Z, Dudek E, Fan X, Mizianty MJ, Dufey E, Urra H, Sepulveda D, Rojas-Rivera D, Lim Y, Kim do H, Baretta K, Srikanth S, Gwack Y, Ahnn J, Kaufman RJ, Lee SK, Hetz C, Kurgan L, Michalak M.

Sci Signal. 2014 Jun 10;7(329):ra54. doi: 10.1126/scisignal.2004983.

PMID:
24917591
[PubMed - in process]
2.

Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis.

Nassif M, Valenzuela V, Rojas-Rivera D, Vidal R, Matus S, Castillo K, Fuentealba Y, Kroemer G, Levine B, Hetz C.

Autophagy. 2014 Jul 1;10(7):1256-71. doi: 10.4161/auto.28784. Epub 2014 May 12.

PMID:
24905722
[PubMed - in process]
3.

Common ground: stem cell approaches find shared pathways underlying ALS.

Matus S, Medinas DB, Hetz C.

Cell Stem Cell. 2014 Jun 5;14(6):697-9. doi: 10.1016/j.stem.2014.05.001.

PMID:
24905158
[PubMed - in process]
4.

A novel ER stress-independent function of the UPR in angiogenesis.

Urra H, Hetz C.

Mol Cell. 2014 May 22;54(4):542-4. doi: 10.1016/j.molcel.2014.05.013.

PMID:
24856218
[PubMed - indexed for MEDLINE]
5.

Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1.

Valdés P, Mercado G, Vidal RL, Molina C, Parsons G, Court FA, Martinez A, Galleguillos D, Armentano D, Schneider BL, Hetz C.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6804-9. doi: 10.1073/pnas.1321845111. Epub 2014 Apr 21.

PMID:
24753614
[PubMed - indexed for MEDLINE]
6.

The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity.

Campos G, Schmidt-Heck W, Ghallab A, Rochlitz K, Pütter L, Medinas DB, Hetz C, Widera A, Cadenas C, Begher-Tibbe B, Reif R, Günther G, Sachinidis A, Hengstler JG, Godoy P.

Arch Toxicol. 2014 Jun;88(6):1267-80. doi: 10.1007/s00204-014-1240-8. Epub 2014 Apr 20.

PMID:
24748426
[PubMed - in process]
7.

A new method to measure autophagy flux in the nervous system.

Matus S, Valenzuela V, Hetz C.

Autophagy. 2014 Apr;10(4):710-4. doi: 10.4161/auto.28434. Epub 2014 Mar 17.

PMID:
24717689
[PubMed - in process]
8.

Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases.

Hetz C, Mollereau B.

Nat Rev Neurosci. 2014 Apr;15(4):233-49. doi: 10.1038/nrn3689. Epub 2014 Mar 12. Review.

PMID:
24619348
[PubMed - indexed for MEDLINE]
9.

TMBIM protein family: ancestral regulators of cell death.

Rojas-Rivera D, Hetz C.

Oncogene. 2014 Feb 24. doi: 10.1038/onc.2014.6. [Epub ahead of print]

PMID:
24561528
[PubMed - as supplied by publisher]
10.

Memory loss in Alzheimer's disease: are the alterations in the UPR network involved in the cognitive impairment?

Duran-Aniotz C, Martínez G, Hetz C.

Front Aging Neurosci. 2014 Jan 30;6:8. doi: 10.3389/fnagi.2014.00008. eCollection 2014. No abstract available.

PMID:
24523695
[PubMed]
Free PMC Article
11.

Addicted to secrete - novel concepts and targets in cancer therapy.

Dejeans N, Manié S, Hetz C, Bard F, Hupp T, Agostinis P, Samali A, Chevet E.

Trends Mol Med. 2014 May;20(5):242-50. doi: 10.1016/j.molmed.2013.12.003. Epub 2014 Jan 20.

PMID:
24456621
[PubMed - in process]
12.

A failure in energy metabolism and antioxidant uptake precede symptoms of Huntington's disease in mice.

Acuña AI, Esparza M, Kramm C, Beltrán FA, Parra AV, Cepeda C, Toro CA, Vidal RL, Hetz C, Concha II, Brauchi S, Levine MS, Castro MA.

Nat Commun. 2013;4:2917. doi: 10.1038/ncomms3917.

PMID:
24336051
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

ER Dysfunction and Protein Folding Stress in ALS.

Matus S, Valenzuela V, Medinas DB, Hetz C.

Int J Cell Biol. 2013;2013:674751. doi: 10.1155/2013/674751. Epub 2013 Nov 13. Review.

PMID:
24324498
[PubMed]
Free PMC Article
14.

Proteostasis impairment: at the intersection between Alzheimer's disease and diabetes.

Medinas DB, Hetz C.

Cell Metab. 2013 Dec 3;18(6):771-2. doi: 10.1016/j.cmet.2013.11.009.

PMID:
24315366
[PubMed - indexed for MEDLINE]
15.

Measurement of autophagy flux in the nervous system in vivo.

Castillo K, Valenzuela V, Matus S, Nassif M, Oñate M, Fuentealba Y, Encina G, Irrazabal T, Parsons G, Court FA, Schneider BL, Armentano D, Hetz C.

Cell Death Dis. 2013 Nov 14;4:e917. doi: 10.1038/cddis.2013.421.

PMID:
24232093
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Role of the unfolded protein response in organ physiology: lessons from mouse models.

Cornejo VH, Pihán P, Vidal RL, Hetz C.

IUBMB Life. 2013 Dec;65(12):962-75. doi: 10.1002/iub.1224. Epub 2013 Nov 13.

PMID:
24227223
[PubMed - in process]
17.

Herp depletion protects from protein aggregation by up-regulating autophagy.

Quiroga C, Gatica D, Paredes F, Bravo R, Troncoso R, Pedrozo Z, Rodriguez AE, Toro B, Chiong M, Vicencio JM, Hetz C, Lavandero S.

Biochim Biophys Acta. 2013 Dec;1833(12):3295-305. doi: 10.1016/j.bbamcr.2013.09.006. Epub 2013 Oct 9.

PMID:
24120520
[PubMed - indexed for MEDLINE]
18.

Targeting the unfolded protein response in disease.

Hetz C, Chevet E, Harding HP.

Nat Rev Drug Discov. 2013 Sep;12(9):703-19. doi: 10.1038/nrd3976. Review.

PMID:
23989796
[PubMed - indexed for MEDLINE]
19.

When ER stress reaches a dead end.

Urra H, Dufey E, Lisbona F, Rojas-Rivera D, Hetz C.

Biochim Biophys Acta. 2013 Dec;1833(12):3507-17. doi: 10.1016/j.bbamcr.2013.07.024. Epub 2013 Aug 27. Review.

PMID:
23988738
[PubMed - indexed for MEDLINE]
20.

Functional contribution of the transcription factor ATF4 to the pathogenesis of amyotrophic lateral sclerosis.

Matus S, Lopez E, Valenzuela V, Nassif M, Hetz C.

PLoS One. 2013 Jul 18;8(7):e66672. doi: 10.1371/journal.pone.0066672. Print 2013.

PMID:
23874395
[PubMed - indexed for MEDLINE]
Free PMC Article

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