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Results: 1 to 20 of 212

1.

Twofold polyketide branching by a stereoselective enzymatic Michael addition.

Heine D, Sundaram S, Bretschneider T, Hertweck C.

Chem Commun (Camb). 2015 May 21. [Epub ahead of print]

PMID:
25994388
2.

Genome Sequence of Mushroom Soft-Rot Pathogen Janthinobacterium agaricidamnosum.

Graupner K, Lackner G, Hertweck C.

Genome Announc. 2015 Apr 16;3(2). pii: e00277-15. doi: 10.1128/genomeA.00277-15.

3.

Plasticity of the malleobactin pathway and its impact on siderophore action in human pathogenic bacteria.

Franke J, Ishida K, Hertweck C.

Chemistry. 2015 May 26;21(22):8010-4. doi: 10.1002/chem.201500757. Epub 2015 Apr 14.

PMID:
25873483
4.

The fungal quorum-sensing molecule farnesol activates innate immune cells but suppresses cellular adaptive immunity.

Leonhardt I, Spielberg S, Weber M, Albrecht-Eckardt D, Bläss M, Claus R, Barz D, Scherlach K, Hertweck C, Löffler J, Hünniger K, Kurzai O.

MBio. 2015 Mar 17;6(2):e00143. doi: 10.1128/mBio.00143-15.

5.

Decoding and reprogramming complex polyketide assembly lines: prospects for synthetic biology.

Hertweck C.

Trends Biochem Sci. 2015 Apr;40(4):189-99. doi: 10.1016/j.tibs.2015.02.001. Epub 2015 Mar 7. Review.

PMID:
25757401
6.

Dandamycin and chandrananimycin E, benzoxazines from Streptomyces griseus.

Barnes EC, Bezerra-Gomes P, Nett M, Hertweck C.

J Antibiot (Tokyo). 2015 Feb 18. doi: 10.1038/ja.2015.10. [Epub ahead of print]

PMID:
25690358
7.

Freedom and constraint in engineered noncolinear polyketide assembly lines.

Sugimoto Y, Ishida K, Traitcheva N, Busch B, Dahse HM, Hertweck C.

Chem Biol. 2015 Feb 19;22(2):229-40. doi: 10.1016/j.chembiol.2014.12.014. Epub 2015 Feb 5.

PMID:
25660274
8.

Nostopeptolide plays a governing role during cellular differentiation of the symbiotic cyanobacterium Nostoc punctiforme.

Liaimer A, Helfrich EJ, Hinrichs K, Guljamow A, Ishida K, Hertweck C, Dittmann E.

Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1862-7. doi: 10.1073/pnas.1419543112. Epub 2015 Jan 26.

PMID:
25624477
9.

Draft Genome Sequence and Gene Annotation of the Entomopathogenic Fungus Verticillium hemipterigenum.

Horn F, Habel A, Scharf DH, Dworschak J, Brakhage AA, Guthke R, Hertweck C, Linde J.

Genome Announc. 2015 Jan 22;3(1). pii: e01439-14. doi: 10.1128/genomeA.01439-14.

10.

Draft Genome Sequences of Symbiotic and Nonsymbiotic Rhizopus microsporus Strains CBS 344.29 and ATCC 62417.

Horn F, Üzüm Z, Möbius N, Guthke R, Linde J, Hertweck C.

Genome Announc. 2015 Jan 22;3(1). pii: e01370-14. doi: 10.1128/genomeA.01370-14.

11.

Transcriptome analysis of cyclic AMP-dependent protein kinase A-regulated genes reveals the production of the novel natural compound fumipyrrole by Aspergillus fumigatus.

Macheleidt J, Scherlach K, Neuwirth T, Schmidt-Heck W, Straßburger M, Spraker J, Baccile JA, Schroeder FC, Keller NP, Hertweck C, Heinekamp T, Brakhage AA.

Mol Microbiol. 2015 Apr;96(1):148-62. doi: 10.1111/mmi.12926. Epub 2015 Mar 11.

PMID:
25582336
12.

Structure, genetics and function of an exopolysaccharide produced by a bacterium living within fungal hyphae.

Uzum Z, Silipo A, Lackner G, De Felice A, Molinaro A, Hertweck C.

Chembiochem. 2015 Feb 9;16(3):387-92. doi: 10.1002/cbic.201402488. Epub 2014 Dec 21.

PMID:
25530287
13.

Terpenoid biosynthesis off the beaten track: unconventional cyclases and their impact on biomimetic synthesis.

Baunach M, Franke J, Hertweck C.

Angew Chem Int Ed Engl. 2015 Feb 23;54(9):2604-26. doi: 10.1002/anie.201407883. Epub 2014 Dec 8.

PMID:
25488271
14.

Divergolide congeners illuminate alternative reaction channels for ansamycin diversification.

Ding L, Franke J, Hertweck C.

Org Biomol Chem. 2015 Feb 14;13(6):1618-23. doi: 10.1039/c4ob02244k.

PMID:
25464499
15.

Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in anaerobic bacteria.

Letzel AC, Pidot SJ, Hertweck C.

BMC Genomics. 2014 Nov 18;15:983. doi: 10.1186/1471-2164-15-983.

16.

Biosynthesis of the halogenated mycotoxin aspirochlorine in koji mold involves a cryptic amino acid conversion.

Chankhamjon P, Boettger-Schmidt D, Scherlach K, Urbansky B, Lackner G, Kalb D, Dahse HM, Hoffmeister D, Hertweck C.

Angew Chem Int Ed Engl. 2014 Dec 1;53(49):13409-13. doi: 10.1002/anie.201407624. Epub 2014 Oct 10.

PMID:
25302411
17.

Mapping of the modular closthioamide architecture reveals crucial motifs of polythioamide antibiotics.

Kloss F, Chiriac AI, Hertweck C.

Chemistry. 2014 Nov 17;20(47):15451-8. doi: 10.1002/chem.201403836. Epub 2014 Oct 3.

PMID:
25284750
18.

Biosynthesis of antifungal and antibacterial polyketides by Burkholderia gladioli in coculture with Rhizopus microsporus.

Ross C, Opel V, Scherlach K, Hertweck C.

Mycoses. 2014 Dec;57 Suppl 3:48-55. doi: 10.1111/myc.12246. Epub 2014 Sep 23.

PMID:
25250879
19.

Reflecting on the past and looking forward to the future of bridging chemistry and biology.

Crews C, Hertweck C, Shokat K, Suga H, Kostic M.

Chem Biol. 2014 Sep 18;21(9):1035-6. doi: 10.1016/j.chembiol.2014.09.004. No abstract available.

PMID:
25237850
20.

Enzymatic polyketide chain branching to give substituted lactone, lactam, and glutarimide heterocycles.

Heine D, Bretschneider T, Sundaram S, Hertweck C.

Angew Chem Int Ed Engl. 2014 Oct 20;53(43):11645-9. doi: 10.1002/anie.201407282. Epub 2014 Sep 11.

PMID:
25214315
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