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Results: 1 to 20 of 128

1.

PLD3 in non-familial Alzheimer's disease.

Heilmann S, Drichel D, Clarimon J, Fernández V, Lacour A, Wagner H, Thelen M, Hernández I, Fortea J, Alegret M, Blesa R, Mauleón A, Roca MR, Kornhuber J, Peters O, Heun R, Frölich L, Hüll M, Heneka MT, Rüther E, Riedel-Heller S, Scherer M, Wiltfang J, Jessen F, Becker T, Tárraga L, Boada M, Maier W, Lleó A, Ruiz A, Nöthen MM, Ramirez A.

Nature. 2015 Apr 2;520(7545):E3-5. doi: 10.1038/nature14039. No abstract available.

PMID:
25832411
2.

EFNS-ENS/EAN Guideline on concomitant use of cholinesterase inhibitors and memantine in moderate to severe Alzheimer's disease.

Schmidt R, Hofer E, Bouwman FH, Buerger K, Cordonnier C, Fladby T, Galimberti D, Georges J, Heneka MT, Hort J, Laczó J, Molinuevo JL, O'Brien JT, Religa D, Scheltens P, Schott JM, Sorbi S.

Eur J Neurol. 2015 Jun;22(6):889-98. doi: 10.1111/ene.12707. Epub 2015 Mar 25.

PMID:
25808982
3.

Neuroinflammation in Alzheimer's disease.

Heneka MT, Carson MJ, Khoury JE, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, Yamanaka K, Koistinaho J, Latz E, Halle A, Petzold GC, Town T, Morgan D, Shinohara ML, Perry VH, Holmes C, Bazan NG, Brooks DJ, Hunot S, Joseph B, Deigendesch N, Garaschuk O, Boddeke E, Dinarello CA, Breitner JC, Cole GM, Golenbock DT, Kummer MP.

Lancet Neurol. 2015 Apr;14(4):388-405. doi: 10.1016/S1474-4422(15)70016-5. Review.

PMID:
25792098
4.

Innate immunity in Alzheimer's disease.

Heneka MT, Golenbock DT, Latz E.

Nat Immunol. 2015 Mar;16(3):229-36. doi: 10.1038/ni.3102. Review.

PMID:
25689443
5.

A distinct clinical phenotype in a German kindred with motor neuron disease carrying a CHCHD10 mutation.

Kurzwelly D, Krüger S, Biskup S, Heneka MT.

Brain. 2015 Feb 12. pii: awv014. [Epub ahead of print] No abstract available.

PMID:
25681414
6.

CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model.

Krauthausen M, Kummer MP, Zimmermann J, Reyes-Irisarri E, Terwel D, Bulic B, Heneka MT, Müller M.

J Clin Invest. 2015 Jan;125(1):365-78. doi: 10.1172/JCI66771. Epub 2014 Dec 15.

PMID:
25500888
7.

Cortical thinning in individuals with subjective memory impairment.

Meiberth D, Scheef L, Wolfsgruber S, Boecker H, Block W, Träber F, Erk S, Heneka MT, Jacobi H, Spottke A, Walter H, Wagner M, Hu X, Jessen F.

J Alzheimers Dis. 2015;45(1):139-46. doi: 10.3233/JAD-142322.

PMID:
25471190
8.

Sepsis-associated encephalopathy versus sepsis-induced encephalopathy--authors' reply.

Widmann CN, Schewe JC, Heneka MT.

Lancet Neurol. 2014 Oct;13(10):968-9. doi: 10.1016/S1474-4422(14)70204-2. No abstract available.

PMID:
25231518
9.

Macrophages derived from infiltrating monocytes mediate autoimmune myelin destruction.

Heneka MT.

J Exp Med. 2014 Jul 28;211(8):1500. doi: 10.1084/jem.2118insight1. No abstract available.

10.

Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes.

Thelen M, Razquin C, Hernández I, Gorostidi A, Sánchez-Valle R, Ortega-Cubero S, Wolfsgruber S, Drichel D, Fliessbach K, Duenkel T, Damian M, Heilmann S, Slotosch A, Lennarz M, Seijo-Martínez M, Rene R, Kornhuber J, Peters O, Luckhaus C, Jahn H, Hüll M, Rüther E, Wiltfang J, Lorenzo E, Gascon J, Lleó A, Lladó A, Campdelacreu J, Moreno F, Ahmadzadehfar H; Dementia Genetics Spanish Consortium (DEGESCO), Fortea J, Indakoetxea B, Heneka MT, Wetter A, Pastor MA, Riverol M, Becker T, Frölich L, Tárraga L, Boada M, Wagner M, Jessen F, Maier W, Clarimón J, López de Munain A, Ruiz A, Pastor P, Ramirez A.

Neurobiol Aging. 2014 Nov;35(11):2657.e13-9. doi: 10.1016/j.neurobiolaging.2014.06.018. Epub 2014 Jun 20.

PMID:
25042114
11.

Truncated and modified amyloid-beta species.

Kummer MP, Heneka MT.

Alzheimers Res Ther. 2014 May 26;6(3):28. doi: 10.1186/alzrt258. eCollection 2014. Review.

PMID:
25031638
12.

SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.

Ramirez A, van der Flier WM, Herold C, Ramonet D, Heilmann S, Lewczuk P, Popp J, Lacour A, Drichel D, Louwersheimer E, Kummer MP, Cruchaga C, Hoffmann P, Teunissen C, Holstege H, Kornhuber J, Peters O, Naj AC, Chouraki V, Bellenguez C, Gerrish A; International Genomics of Alzheimer's Project (IGAP); Alzheimer's Disease Neuroimaging Initiative (ADNI), Heun R, Frölich L, Hüll M, Buscemi L, Herms S, Kölsch H, Scheltens P, Breteler MM, Rüther E, Wiltfang J, Goate A, Jessen F, Maier W, Heneka MT, Becker T, Nöthen MM.

Hum Mol Genet. 2014 Dec 15;23(24):6644-58. doi: 10.1093/hmg/ddu372. Epub 2014 Jul 15.

PMID:
25027320
13.

Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.

Gockel I, Becker J, Wouters MM, Niebisch S, Gockel HR, Hess T, Ramonet D, Zimmermann J, Vigo AG, Trynka G, de León AR, de la Serna JP, Urcelay E, Kumar V, Franke L, Westra HJ, Drescher D, Kneist W, Marquardt JU, Galle PR, Mattheisen M, Annese V, Latiano A, Fumagalli U, Laghi L, Cuomo R, Sarnelli G, Müller M, Eckardt AJ, Tack J, Hoffmann P, Herms S, Mangold E, Heilmann S, Kiesslich R, von Rahden BH, Allescher HD, Schulz HG, Wijmenga C, Heneka MT, Lang H, Hopfner KP, Nöthen MM, Boeckxstaens GE, de Bakker PI, Knapp M, Schumacher J.

Nat Genet. 2014 Aug;46(8):901-4. doi: 10.1038/ng.3029. Epub 2014 Jul 6.

PMID:
24997987
14.

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.

Kleinberger G, Yamanishi Y, Suárez-Calvet M, Czirr E, Lohmann E, Cuyvers E, Struyfs H, Pettkus N, Wenninger-Weinzierl A, Mazaheri F, Tahirovic S, Lleó A, Alcolea D, Fortea J, Willem M, Lammich S, Molinuevo JL, Sánchez-Valle R, Antonell A, Ramirez A, Heneka MT, Sleegers K, van der Zee J, Martin JJ, Engelborghs S, Demirtas-Tatlidede A, Zetterberg H, Van Broeckhoven C, Gurvit H, Wyss-Coray T, Hardy J, Colonna M, Haass C.

Sci Transl Med. 2014 Jul 2;6(243):243ra86. doi: 10.1126/scitranslmed.3009093.

PMID:
24990881
15.

Ear2 deletion causes early memory and learning deficits in APP/PS1 mice.

Kummer MP, Hammerschmidt T, Martinez A, Terwel D, Eichele G, Witten A, Figura S, Stoll M, Schwartz S, Pape HC, Schultze JL, Weinshenker D, Heneka MT, Urban I.

J Neurosci. 2014 Jun 25;34(26):8845-54. doi: 10.1523/JNEUROSCI.4027-13.2014. Erratum in: J Neurosci. 2015 Feb 4;35(5):2321. Urban, Inga [Added].

16.

Innate immune activation in neurodegenerative disease.

Heneka MT, Kummer MP, Latz E.

Nat Rev Immunol. 2014 Jul;14(7):463-77. doi: 10.1038/nri3705. Review.

PMID:
24962261
17.

CXCR3 modulates glial accumulation and activation in cuprizone-induced demyelination of the central nervous system.

Krauthausen M, Saxe S, Zimmermann J, Emrich M, Heneka MT, Müller M.

J Neuroinflammation. 2014 Jun 16;11:109. doi: 10.1186/1742-2094-11-109.

18.

Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration.

van der Zee J, Van Langenhove T, Kovacs GG, Dillen L, Deschamps W, Engelborghs S, Matěj R, Vandenbulcke M, Sieben A, Dermaut B, Smets K, Van Damme P, Merlin C, Laureys A, Van Den Broeck M, Mattheijssens M, Peeters K, Benussi L, Binetti G, Ghidoni R, Borroni B, Padovani A, Archetti S, Pastor P, Razquin C, Ortega-Cubero S, Hernández I, Boada M, Ruiz A, de Mendonça A, Miltenberger-Miltényi G, do Couto FS, Sorbi S, Nacmias B, Bagnoli S, Graff C, Chiang HH, Thonberg H, Perneczky R, Diehl-Schmid J, Alexopoulos P, Frisoni GB, Bonvicini C, Synofzik M, Maetzler W, vom Hagen JM, Schöls L, Haack TB, Strom TM, Prokisch H, Dols-Icardo O, Clarimón J, Lleó A, Santana I, Almeida MR, Santiago B, Heneka MT, Jessen F, Ramirez A, Sanchez-Valle R, Llado A, Gelpi E, Sarafov S, Tournev I, Jordanova A, Parobkova E, Fabrizi GM, Testi S, Salmon E, Ströbel T, Santens P, Robberecht W, De Jonghe P, Martin JJ, Cras P, Vandenberghe R, De Deyn PP, Cruts M, Sleegers K, Van Broeckhoven C.

Acta Neuropathol. 2014 Sep;128(3):397-410. doi: 10.1007/s00401-014-1298-7. Epub 2014 Jun 5.

19.

Long-term cerebral consequences of sepsis.

Widmann CN, Heneka MT.

Lancet Neurol. 2014 Jun;13(6):630-6. doi: 10.1016/S1474-4422(14)70017-1.

PMID:
24849863
20.

Pan-PPAR modulation effectively protects APP/PS1 mice from amyloid deposition and cognitive deficits.

Kummer MP, Schwarzenberger R, Sayah-Jeanne S, Dubernet M, Walczak R, Hum DW, Schwartz S, Axt D, Heneka MT.

Mol Neurobiol. 2015 Apr;51(2):661-71. doi: 10.1007/s12035-014-8743-4. Epub 2014 May 17.

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