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Results: 1 to 20 of 290

1.

hMOB3 Modulates MST1 Apoptotic Signaling and Supports Tumor Growth in Glioblastoma Multiforme.

Tang F, Zhang L, Xue G, Hynx D, Wang Y, Cron PD, Hundsrucker C, Hergovich A, Frank S, Hemmings BA, Schmitz-Rohmer D.

Cancer Res. 2014 Jul 15;74(14):3779-89. doi: 10.1158/0008-5472.CAN-13-3430. Epub 2014 May 28.

PMID:
24872389
[PubMed - in process]
2.

Reduced hepatic lipid content in Pten-haplodeficient mice because of enhanced AKT2/PKBβ activation in skeletal muscle.

Schultze SM, Dietrich M, Hynx D, Geier A, Niessen M, Spinas GA, Hemmings BA, Tschopp O.

Liver Int. 2014 May 20. doi: 10.1111/liv.12600. [Epub ahead of print]

PMID:
24845341
[PubMed - as supplied by publisher]
3.

Novel individual metabolic profile characterizes the protein kinase B-alpha (pkbα-/-) in vivo model.

Eberle C, Niessen M, Hemmings BA, Tschopp O, Ament C.

Arch Physiol Biochem. 2014 Apr 28. [Epub ahead of print]

PMID:
24773499
[PubMed - as supplied by publisher]
4.

MNK1 pathway activity maintains protein synthesis in rapalog-treated gliomas.

Grzmil M, Huber RM, Hess D, Frank S, Hynx D, Moncayo G, Klein D, Merlo A, Hemmings BA.

J Clin Invest. 2014 Feb 3;124(2):742-54. doi: 10.1172/JCI70198. Epub 2014 Jan 9.

PMID:
24401275
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Multimodal imaging reveals a role for Akt1 in fetal cardiac development.

Vandoorne K, Vandsburger MH, Weisinger K, Brumfeld V, Hemmings BA, Harmelin A, Neeman M.

Physiol Rep. 2013 Nov;1(6):e00143. doi: 10.1002/phy2.143. Epub 2013 Nov 7.

PMID:
24400145
[PubMed]
Free PMC Article
6.

Chronic Akt1 deficiency attenuates adverse remodeling and enhances angiogenesis after myocardial infarction.

Vandoorne K, Vandsburger MH, Raz T, Shalev M, Weisinger K, Biton I, Brumfeld V, Raanan C, Nevo N, Eilam R, Hemmings BA, Tzahor E, Harmelin A, Gepstein L, Neeman M.

Circ Cardiovasc Imaging. 2013 Nov;6(6):992-1000. doi: 10.1161/CIRCIMAGING.113.000828. Epub 2013 Oct 17.

PMID:
24134954
[PubMed - indexed for MEDLINE]
7.

Characterization of fragmented 3-phosphoinsitide-dependent protein kinase-1 (PDK1) by phosphosite-specific antibodies.

Park J, Li Y, Kim SH, Kong G, Shrestha R, Tran Q, Hong J, Hur GM, Hemmings BA, Koo BS, Park J.

Life Sci. 2013 Nov 4;93(18-19):700-6. doi: 10.1016/j.lfs.2013.09.007. Epub 2013 Sep 15.

PMID:
24044887
[PubMed - indexed for MEDLINE]
8.

Akt1 is the principal Akt isoform regulating apoptosis in limiting cytokine concentrations.

Green BD, Jabbour AM, Sandow JJ, Riffkin CD, Masouras D, Daunt CP, Salmanidis M, Brumatti G, Hemmings BA, Guthridge MA, Pearson RB, Ekert PG.

Cell Death Differ. 2013 Oct;20(10):1341-9. doi: 10.1038/cdd.2013.63. Epub 2013 Jun 21.

PMID:
23787999
[PubMed - indexed for MEDLINE]
9.

Deltex-1 activates mitotic signaling and proliferation and increases the clonogenic and invasive potential of U373 and LN18 glioblastoma cells and correlates with patient survival.

Huber RM, Rajski M, Sivasankaran B, Moncayo G, Hemmings BA, Merlo A.

PLoS One. 2013;8(2):e57793. doi: 10.1371/journal.pone.0057793. Epub 2013 Feb 25.

PMID:
23451269
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Overcoming resistance to rapalogs in gliomas by combinatory therapies.

Grzmil M, Hemmings BA.

Biochim Biophys Acta. 2013 Jul;1834(7):1371-80. doi: 10.1016/j.bbapap.2013.01.041. Epub 2013 Feb 8. Review.

PMID:
23395884
[PubMed - indexed for MEDLINE]
Free Article
11.

PKB/Akt-dependent regulation of cell motility.

Xue G, Hemmings BA.

J Natl Cancer Inst. 2013 Mar 20;105(6):393-404. doi: 10.1093/jnci/djs648. Epub 2013 Jan 25.

PMID:
23355761
[PubMed - indexed for MEDLINE]
Free Article
12.

PKB-mediated PHF20 phosphorylation on Ser291 is required for p53 function in DNA damage.

Li Y, Park J, Piao L, Kong G, Kim Y, Park KA, Zhang T, Hong J, Hur GM, Seok JH, Choi SW, Yoo BC, Hemmings BA, Brazil DP, Kim SH, Park J.

Cell Signal. 2013 Jan;25(1):74-84. doi: 10.1016/j.cellsig.2012.09.009. Epub 2012 Sep 11.

PMID:
22975685
[PubMed - indexed for MEDLINE]
13.

PI3K-PKB/Akt pathway.

Hemmings BA, Restuccia DF.

Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a011189. doi: 10.1101/cshperspect.a011189. Review. No abstract available.

PMID:
22952397
[PubMed - indexed for MEDLINE]
14.

Acentrosomal spindle organization renders cancer cells dependent on the kinesin HSET.

Kleylein-Sohn J, Pöllinger B, Ohmer M, Hofmann F, Nigg EA, Hemmings BA, Wartmann M.

J Cell Sci. 2012 Nov 15;125(Pt 22):5391-402. doi: 10.1242/jcs.107474. Epub 2012 Sep 3.

PMID:
22946058
[PubMed - indexed for MEDLINE]
Free Article
15.

Translation regulation as a therapeutic target in cancer.

Grzmil M, Hemmings BA.

Cancer Res. 2012 Aug 15;72(16):3891-900. doi: 10.1158/0008-5472.CAN-12-0026. Epub 2012 Jul 31. Review.

PMID:
22850420
[PubMed - indexed for MEDLINE]
Free Article
16.

Constitutive Notch2 signaling in neural stem cells promotes tumorigenic features and astroglial lineage entry.

Tchorz JS, Tome M, Cloëtta D, Sivasankaran B, Grzmil M, Huber RM, Rutz-Schatzmann F, Kirchhoff F, Schaeren-Wiemers N, Gassmann M, Hemmings BA, Merlo A, Bettler B.

Cell Death Dis. 2012 Jun 21;3:e325. doi: 10.1038/cddis.2012.65.

PMID:
22717580
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Acyl coenzyme A thioesterase Them5/Acot15 is involved in cardiolipin remodeling and fatty liver development.

Zhuravleva E, Gut H, Hynx D, Marcellin D, Bleck CK, Genoud C, Cron P, Keusch JJ, Dummler B, Esposti MD, Hemmings BA.

Mol Cell Biol. 2012 Jul;32(14):2685-97. doi: 10.1128/MCB.00312-12. Epub 2012 May 14.

PMID:
22586271
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Akt/PKB-mediated phosphorylation of Twist1 promotes tumor metastasis via mediating cross-talk between PI3K/Akt and TGF-β signaling axes.

Xue G, Restuccia DF, Lan Q, Hynx D, Dirnhofer S, Hess D, Rüegg C, Hemmings BA.

Cancer Discov. 2012 Mar;2(3):248-59. doi: 10.1158/2159-8290.CD-11-0270. Epub 2012 Jan 25.

PMID:
22585995
[PubMed - indexed for MEDLINE]
19.

Hippo signalling in the G2/M cell cycle phase: lessons learned from the yeast MEN and SIN pathways.

Hergovich A, Hemmings BA.

Semin Cell Dev Biol. 2012 Sep;23(7):794-802. doi: 10.1016/j.semcdb.2012.04.001. Epub 2012 Apr 15. Review.

PMID:
22525225
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Mer receptor tyrosine kinase promotes invasion and survival in glioblastoma multiforme.

Wang Y, Moncayo G, Morin P Jr, Xue G, Grzmil M, Lino MM, Clément-Schatlo V, Frank S, Merlo A, Hemmings BA.

Oncogene. 2013 Feb 14;32(7):872-82. doi: 10.1038/onc.2012.104. Epub 2012 Apr 2.

PMID:
22469987
[PubMed - indexed for MEDLINE]

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