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Results: 1 to 20 of 36

1.

Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA.

Almagro JC, Gilliland GL, Breden F, Scott JK, Sok D, Pauthner M, Reichert JM, Helguera G, Andrabi R, Mabry R, Bléry M, Voss JE, Laurén J, Abuqayyas L, Barghorn S, Ben-Jacob E, Crowe JE Jr, Huston JS, Johnston SA, Krauland E, Lund-Johansen F, Marasco WA, Parren PW, Xu KY.

MAbs. 2014 May-Jun;6(3):577-618. doi: 10.4161/mabs.28421. Epub 2014 Mar 3.

PMID:
24589717
[PubMed - in process]
Free Article
2.

Rationale and preclinical efficacy of a novel anti-EMP2 antibody for the treatment of invasive breast cancer.

Fu M, Maresh EL, Helguera GF, Kiyohara M, Qin Y, Ashki N, Daniels-Wells TR, Aziz N, Gordon LK, Braun J, Elshimali Y, Soslow RA, Penichet ML, Goodglick L, Wadehra M.

Mol Cancer Ther. 2014 Apr;13(4):902-15. doi: 10.1158/1535-7163.MCT-13-0199. Epub 2014 Jan 21.

PMID:
24448822
[PubMed - in process]
3.

Paclitaxel-loaded PCL-TPGS nanoparticles: in vitro and in vivo performance compared with Abraxane®.

Bernabeu E, Helguera G, Legaspi MJ, Gonzalez L, Hocht C, Taira C, Chiappetta DA.

Colloids Surf B Biointerfaces. 2014 Jan 1;113:43-50. doi: 10.1016/j.colsurfb.2013.07.036. Epub 2013 Sep 5.

PMID:
24060929
[PubMed - in process]
4.

Polymalic acid nanobioconjugate for simultaneous immunostimulation and inhibition of tumor growth in HER2/neu-positive breast cancer.

Ding H, Helguera G, Rodríguez JA, Markman J, Luria-Pérez R, Gangalum P, Portilla-Arias J, Inoue S, Daniels-Wells TR, Black K, Holler E, Penichet ML, Ljubimova JY.

J Control Release. 2013 Nov 10;171(3):322-9. doi: 10.1016/j.jconrel.2013.06.001. Epub 2013 Jun 12.

PMID:
23770212
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A novel IgE antibody targeting the prostate-specific antigen as a potential prostate cancer therapy.

Daniels-Wells TR, Helguera G, Leuchter RK, Quintero R, Kozman M, Rodríguez JA, Ortiz-Sánchez E, Martínez-Maza O, Schultes BC, Nicodemus CF, Penichet ML.

BMC Cancer. 2013 Apr 17;13:195. doi: 10.1186/1471-2407-13-195.

PMID:
23594731
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Adaptive downregulation of mitochondrial function in down syndrome.

Helguera P, Seiglie J, Rodriguez J, Hanna M, Helguera G, Busciglio J.

Cell Metab. 2013 Jan 8;17(1):132-40. doi: 10.1016/j.cmet.2012.12.005.

PMID:
23312288
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Insights into the mechanism of cell death induced by saporin delivered into cancer cells by an antibody fusion protein targeting the transferrin receptor 1.

Daniels-Wells TR, Helguera G, Rodríguez JA, Leoh LS, Erb MA, Diamante G, Casero D, Pellegrini M, Martínez-Maza O, Penichet ML.

Toxicol In Vitro. 2013 Feb;27(1):220-31. doi: 10.1016/j.tiv.2012.10.006. Epub 2012 Oct 17.

PMID:
23085102
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

IBC's 22nd Annual Antibody Engineering and 9th Annual Antibody Therapeutics International Conferences and the 2011 Annual Meeting of The Antibody Society, December 5-8, 2011, San Diego, CA.

Nilvebrant J, Dunlop DC, Sircar A, Wurch T, Falkowska E, Reichert JM, Helguera G, Piccione EC, Brack S, Berger S.

MAbs. 2012 Mar-Apr;4(2):153-81. doi: 10.4161/mabs.4.2.19495. Epub 2012 Mar 1.

PMID:
22453091
[PubMed - in process]
Free PMC Article
9.

An antibody recognizing the apical domain of human transferrin receptor 1 efficiently inhibits the entry of all new world hemorrhagic Fever arenaviruses.

Helguera G, Jemielity S, Abraham J, Cordo SM, Martinez MG, Rodríguez JA, Bregni C, Wang JJ, Farzan M, Penichet ML, Candurra NA, Choe H.

J Virol. 2012 Apr;86(7):4024-8. doi: 10.1128/JVI.06397-11. Epub 2012 Jan 25.

PMID:
22278244
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Targeting HER2/neu with a fully human IgE to harness the allergic reaction against cancer cells.

Daniels TR, Leuchter RK, Quintero R, Helguera G, Rodríguez JA, Martínez-Maza O, Schultes BC, Nicodemus CF, Penichet ML.

Cancer Immunol Immunother. 2012 Jul;61(7):991-1003. doi: 10.1007/s00262-011-1150-z. Epub 2011 Nov 30.

PMID:
22127364
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Lethal iron deprivation induced by non-neutralizing antibodies targeting transferrin receptor 1 in malignant B cells.

Rodríguez JA, Luria-Pérez R, López-Valdés HE, Casero D, Daniels TR, Patel S, Avila D, Leuchter R, So S, Ortiz-Sánchez E, Bonavida B, Martínez-Maza O, Charles AC, Pellegrini M, Helguera G, Penichet ML.

Leuk Lymphoma. 2011 Nov;52(11):2169-78. doi: 10.3109/10428194.2011.596964. Epub 2011 Aug 28.

PMID:
21870996
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The transferrin receptor and the targeted delivery of therapeutic agents against cancer.

Daniels TR, Bernabeu E, Rodríguez JA, Patel S, Kozman M, Chiappetta DA, Holler E, Ljubimova JY, Helguera G, Penichet ML.

Biochim Biophys Acta. 2012 Mar;1820(3):291-317. doi: 10.1016/j.bbagen.2011.07.016. Epub 2011 Aug 5. Review.

PMID:
21851850
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

An antibody-based multifaceted approach targeting the human transferrin receptor for the treatment of B-cell malignancies.

Daniels TR, Ortiz-Sánchez E, Luria-Pérez R, Quintero R, Helguera G, Bonavida B, Martínez-Maza O, Penichet ML.

J Immunother. 2011 Jul-Aug;34(6):500-8. doi: 10.1097/CJI.0b013e318222ffc8.

PMID:
21654517
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Visualization and quantification of cytotoxicity mediated by antibodies using imaging flow cytometry.

Helguera G, Rodríguez JA, Luria-Pérez R, Henery S, Catterton P, Bregni C, George TC, Martínez-Maza O, Penichet ML.

J Immunol Methods. 2011 May 31;368(1-2):54-63. doi: 10.1016/j.jim.2011.03.003. Epub 2011 Mar 21. Erratum in: J Immunol Methods. 2011 Aug 31;371(1-2):174.

PMID:
21420412
[PubMed - indexed for MEDLINE]
15.

Inhibition of NF-kappaB and Akt pathways by an antibody-avidin fusion protein sensitizes malignant B-cells to cisplatin-induced apoptosis.

Suzuki E, Daniels TR, Helguera G, Penichet ML, Umezawa K, Bonavida B.

Int J Oncol. 2010 May;36(5):1299-307.

PMID:
20372806
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Propulsion of African trypanosomes is driven by bihelical waves with alternating chirality separated by kinks.

Rodríguez JA, Lopez MA, Thayer MC, Zhao Y, Oberholzer M, Chang DD, Kisalu NK, Penichet ML, Helguera G, Bruinsma R, Hill KL, Miao J.

Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19322-7. doi: 10.1073/pnas.0907001106. Epub 2009 Oct 30.

PMID:
19880745
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A versatile targeting system with lentiviral vectors bearing the biotin-adaptor peptide.

Morizono K, Xie Y, Helguera G, Daniels TR, Lane TF, Penichet ML, Chen IS.

J Gene Med. 2009 Aug;11(8):655-63. doi: 10.1002/jgm.1345.

PMID:
19455593
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Changes in global gene expression in rat myometrium in transition from late pregnancy to parturition.

Helguera G, Eghbali M, Sforza D, Minosyan TY, Toro L, Stefani E.

Physiol Genomics. 2009 Jan 8;36(2):89-97. doi: 10.1152/physiolgenomics.00290.2007. Epub 2008 Nov 11.

PMID:
19001510
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Enhanced cytotoxicity of an anti-transferrin receptor IgG3-avidin fusion protein in combination with gambogic acid against human malignant hematopoietic cells: functional relevance of iron, the receptor, and reactive oxygen species.

Ortiz-Sánchez E, Daniels TR, Helguera G, Martinez-Maza O, Bonavida B, Penichet ML.

Leukemia. 2009 Jan;23(1):59-70. doi: 10.1038/leu.2008.270. Epub 2008 Oct 23.

PMID:
18946492
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Antibody-cytokine fusion proteins: applications in cancer therapy.

Ortiz-Sánchez E, Helguera G, Daniels TR, Penichet ML.

Expert Opin Biol Ther. 2008 May;8(5):609-32. doi: 10.1517/14712598.8.5.609 . Review. Erratum in: Expert Opin Biol Ther. 2008 Jul;8(7):1037.

PMID:
18407765
[PubMed - indexed for MEDLINE]

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