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Results: 1 to 20 of 507

1.

Fine-Tuning of Smad Protein Function by Poly(ADP-Ribose) Polymerases and Poly(ADP-Ribose) Glycohydrolase during Transforming Growth Factor β Signaling.

Dahl M, Maturi V, Lönn P, Papoutsoglou P, Zieba A, Vanlandewijck M, van der Heide LP, Watanabe Y, Söderberg O, Hottiger MO, Heldin CH, Moustakas A.

PLoS One. 2014 Aug 18;9(8):e103651. doi: 10.1371/journal.pone.0103651. eCollection 2014.

PMID:
25133494
[PubMed - in process]
Free PMC Article
2.

TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1.

Thakur N, Gudey SK, Marcusson A, Fu JY, Bergh A, Heldin CH, Landström M.

Cell Cycle. 2014 Jun 19;13(15). [Epub ahead of print]

PMID:
24945502
[PubMed - as supplied by publisher]
Free Article
3.

Platelet-derived growth factor β-receptor, transforming growth factor β type I receptor, and CD44 protein modulate each other's signaling and stability.

Porsch H, Mehić M, Olofsson B, Heldin P, Heldin CH.

J Biol Chem. 2014 Jul 11;289(28):19747-57. doi: 10.1074/jbc.M114.547273. Epub 2014 May 23.

PMID:
24860093
[PubMed - in process]
4.

Nucleosome regulatory dynamics in response to TGFβ.

Enroth S, Andersson R, Bysani M, Wallerman O, Termén S, Tuch BB, De La Vega FM, Heldin CH, Moustakas A, Komorowski J, Wadelius C.

Nucleic Acids Res. 2014;42(11):6921-34. doi: 10.1093/nar/gku326. Epub 2014 Apr 25.

PMID:
24771338
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

TRAF6 stimulates the tumor-promoting effects of TGFβ type I receptor through polyubiquitination and activation of presenilin 1.

Gudey SK, Sundar R, Mu Y, Wallenius A, Zang G, Bergh A, Heldin CH, Landström M.

Sci Signal. 2014 Jan 7;7(307):ra2. doi: 10.1126/scisignal.2004207.

PMID:
24399296
[PubMed - indexed for MEDLINE]
6.

Targeting the PDGF signaling pathway in tumor treatment.

Heldin CH.

Cell Commun Signal. 2013 Dec 20;11:97. doi: 10.1186/1478-811X-11-97. Review.

PMID:
24359404
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Coordination of TGF-β signaling by ubiquitylation.

Moustakas A, Heldin CH.

Mol Cell. 2013 Sep 12;51(5):555-6. doi: 10.1016/j.molcel.2013.08.034.

PMID:
24034692
[PubMed - indexed for MEDLINE]
8.

Structural and functional properties of platelet-derived growth factor and stem cell factor receptors.

Heldin CH, Lennartsson J.

Cold Spring Harb Perspect Biol. 2013 Aug 1;5(8):a009100. doi: 10.1101/cshperspect.a009100. Review.

PMID:
23906712
[PubMed - indexed for MEDLINE]
9.

Targeting the PDGF signaling pathway in the treatment of non-malignant diseases.

Heldin CH.

J Neuroimmune Pharmacol. 2014 Mar;9(2):69-79. doi: 10.1007/s11481-013-9484-2. Epub 2013 Jun 25.

PMID:
23793451
[PubMed - in process]
10.

The Fer tyrosine kinase is important for platelet-derived growth factor-BB-induced signal transducer and activator of transcription 3 (STAT3) protein phosphorylation, colony formation in soft agar, and tumor growth in vivo.

Lennartsson J, Ma H, Wardega P, Pelka K, Engström U, Hellberg C, Heldin CH.

J Biol Chem. 2013 May 31;288(22):15736-44. doi: 10.1074/jbc.M113.476424. Epub 2013 Apr 15.

PMID:
23589302
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Snail depletes the tumorigenic potential of glioblastoma.

Savary K, Caglayan D, Caja L, Tzavlaki K, Bin Nayeem S, Bergström T, Jiang Y, Uhrbom L, Forsberg-Nilsson K, Westermark B, Heldin CH, Ferletta M, Moustakas A.

Oncogene. 2013 Nov 21;32(47):5409-20. doi: 10.1038/onc.2013.67. Epub 2013 Mar 25.

PMID:
23524585
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Dynamin inhibitors impair endocytosis and mitogenic signaling of PDGF.

Sadowski Ł, Jastrzębski K, Kalaidzidis Y, Heldin CH, Hellberg C, Miaczynska M.

Traffic. 2013 Jun;14(6):725-36. doi: 10.1111/tra.12061. Epub 2013 Mar 12.

PMID:
23425318
[PubMed - indexed for MEDLINE]
Free PMC Article
13.
14.

Efficient TGFβ-induced epithelial-mesenchymal transition depends on hyaluronan synthase HAS2.

Porsch H, Bernert B, Mehić M, Theocharis AD, Heldin CH, Heldin P.

Oncogene. 2013 Sep 12;32(37):4355-65. doi: 10.1038/onc.2012.475. Epub 2012 Oct 29.

PMID:
23108409
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

p53 regulates epithelial-mesenchymal transition induced by transforming growth factor β.

Termén S, Tan EJ, Heldin CH, Moustakas A.

J Cell Physiol. 2013 Apr;228(4):801-13. doi: 10.1002/jcp.24229.

PMID:
23018556
[PubMed - indexed for MEDLINE]
16.

Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion.

Sundqvist A, Zieba A, Vasilaki E, Herrera Hidalgo C, Söderberg O, Koinuma D, Miyazono K, Heldin CH, Landegren U, Ten Dijke P, van Dam H.

Oncogene. 2013 Aug 1;32(31):3606-15. doi: 10.1038/onc.2012.370. Epub 2012 Aug 27.

PMID:
22926518
[PubMed - indexed for MEDLINE]
17.

Regulation of EMT by TGFβ in cancer.

Heldin CH, Vanlandewijck M, Moustakas A.

FEBS Lett. 2012 Jul 4;586(14):1959-70. doi: 10.1016/j.febslet.2012.02.037. Epub 2012 Feb 28. Review.

PMID:
22710176
[PubMed - indexed for MEDLINE]
Free Article
18.

Genome-wide mechanisms of Smad binding.

Morikawa M, Koinuma D, Miyazono K, Heldin CH.

Oncogene. 2013 Mar 28;32(13):1609-15. doi: 10.1038/onc.2012.191. Epub 2012 May 21. Review.

PMID:
22614010
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Macropinocytosis of the PDGF β-receptor promotes fibroblast transformation by H-RasG12V.

Schmees C, Villaseñor R, Zheng W, Ma H, Zerial M, Heldin CH, Hellberg C.

Mol Biol Cell. 2012 Jul;23(13):2571-82. doi: 10.1091/mbc.E11-04-0317. Epub 2012 May 9.

PMID:
22573884
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Induction of epithelial-mesenchymal transition by transforming growth factor β.

Moustakas A, Heldin CH.

Semin Cancer Biol. 2012 Oct;22(5-6):446-54. doi: 10.1016/j.semcancer.2012.04.002. Epub 2012 Apr 23. Review.

PMID:
22548724
[PubMed - indexed for MEDLINE]

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