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Results: 1 to 20 of 513

1.

CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface.

Yakymovych I, Yakymovych M, Zang G, Mu Y, Bergh A, Landström M, Heldin CH.

J Cell Biol. 2015 Jul 20;210(2):319-332. Epub 2015 Jul 13.

PMID:
26169354
2.

Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling through ERK1/2.

Carthy JM, Sundqvist A, Heldin A, van Dam H, Kletsas D, Heldin CH, Moustakas A.

J Cell Physiol. 2015 Jun 10. doi: 10.1002/jcp.25049. [Epub ahead of print]

PMID:
26096876
3.

TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor.

Sundar R, Gudey SK, Heldin CH, Landström M.

Cell Cycle. 2015;14(4):554-65. doi: 10.4161/15384101.2014.990302.

PMID:
25622187
4.

The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition.

Tan EJ, Kahata K, Idås O, Thuault S, Heldin CH, Moustakas A.

Nucleic Acids Res. 2015 Jan;43(1):162-78. doi: 10.1093/nar/gku1293. Epub 2014 Dec 9.

5.

TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1.

Thakur N, Gudey SK, Marcusson A, Fu JY, Bergh A, Heldin CH, Landström M.

Cell Cycle. 2014;13(15):2400-14. doi: 10.4161/cc.29339.

PMID:
25483191
6.

Tony Pawson (1952-2013).

Heldin CH.

Growth Factors. 2014 Dec;32(6):174-5. doi: 10.3109/08977194.2014.983500. Epub 2014 Nov 17. No abstract available.

PMID:
25401412
7.

NR4A1 promotes PDGF-BB-induced cell colony formation in soft agar.

Eger G, Papadopoulos N, Lennartsson J, Heldin CH.

PLoS One. 2014 Sep 30;9(9):e109047. doi: 10.1371/journal.pone.0109047. eCollection 2014.

8.

Fine-tuning of Smad protein function by poly(ADP-ribose) polymerases and poly(ADP-ribose) glycohydrolase during transforming growth factor β signaling.

Dahl M, Maturi V, Lönn P, Papoutsoglou P, Zieba A, Vanlandewijck M, van der Heide LP, Watanabe Y, Söderberg O, Hottiger MO, Heldin CH, Moustakas A.

PLoS One. 2014 Aug 18;9(8):e103651. doi: 10.1371/journal.pone.0103651. eCollection 2014.

9.

Platelet-derived growth factor β-receptor, transforming growth factor β type I receptor, and CD44 protein modulate each other's signaling and stability.

Porsch H, Mehić M, Olofsson B, Heldin P, Heldin CH.

J Biol Chem. 2014 Jul 11;289(28):19747-57. doi: 10.1074/jbc.M114.547273. Epub 2014 May 23.

10.

Nucleosome regulatory dynamics in response to TGFβ.

Enroth S, Andersson R, Bysani M, Wallerman O, Termén S, Tuch BB, De La Vega FM, Heldin CH, Moustakas A, Komorowski J, Wadelius C.

Nucleic Acids Res. 2014 Jun;42(11):6921-34. doi: 10.1093/nar/gku326. Epub 2014 Apr 25.

11.

TRAF6 stimulates the tumor-promoting effects of TGFβ type I receptor through polyubiquitination and activation of presenilin 1.

Gudey SK, Sundar R, Mu Y, Wallenius A, Zang G, Bergh A, Heldin CH, Landström M.

Sci Signal. 2014 Jan 7;7(307):ra2. doi: 10.1126/scisignal.2004207.

PMID:
24399296
12.

Targeting the PDGF signaling pathway in tumor treatment.

Heldin CH.

Cell Commun Signal. 2013 Dec 20;11:97. doi: 10.1186/1478-811X-11-97. Review.

13.

Coordination of TGF-β signaling by ubiquitylation.

Moustakas A, Heldin CH.

Mol Cell. 2013 Sep 12;51(5):555-6. doi: 10.1016/j.molcel.2013.08.034.

14.

Structural and functional properties of platelet-derived growth factor and stem cell factor receptors.

Heldin CH, Lennartsson J.

Cold Spring Harb Perspect Biol. 2013 Aug 1;5(8):a009100. doi: 10.1101/cshperspect.a009100. Review.

PMID:
23906712
15.

Targeting the PDGF signaling pathway in the treatment of non-malignant diseases.

Heldin CH.

J Neuroimmune Pharmacol. 2014 Mar;9(2):69-79. doi: 10.1007/s11481-013-9484-2. Epub 2013 Jun 25.

PMID:
23793451
16.

The Fer tyrosine kinase is important for platelet-derived growth factor-BB-induced signal transducer and activator of transcription 3 (STAT3) protein phosphorylation, colony formation in soft agar, and tumor growth in vivo.

Lennartsson J, Ma H, Wardega P, Pelka K, Engström U, Hellberg C, Heldin CH.

J Biol Chem. 2013 May 31;288(22):15736-44. doi: 10.1074/jbc.M113.476424. Epub 2013 Apr 15.

17.

Snail depletes the tumorigenic potential of glioblastoma.

Savary K, Caglayan D, Caja L, Tzavlaki K, Bin Nayeem S, Bergström T, Jiang Y, Uhrbom L, Forsberg-Nilsson K, Westermark B, Heldin CH, Ferletta M, Moustakas A.

Oncogene. 2013 Nov 21;32(47):5409-20. doi: 10.1038/onc.2013.67. Epub 2013 Mar 25.

18.

Dynamin inhibitors impair endocytosis and mitogenic signaling of PDGF.

Sadowski Ł, Jastrzębski K, Kalaidzidis Y, Heldin CH, Hellberg C, Miaczynska M.

Traffic. 2013 Jun;14(6):725-36. doi: 10.1111/tra.12061. Epub 2013 Mar 12.

19.
20.

Efficient TGFβ-induced epithelial-mesenchymal transition depends on hyaluronan synthase HAS2.

Porsch H, Bernert B, Mehić M, Theocharis AD, Heldin CH, Heldin P.

Oncogene. 2013 Sep 12;32(37):4355-65. doi: 10.1038/onc.2012.475. Epub 2012 Oct 29.

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