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Results: 1 to 20 of 62

1.

Non-promoter DNA hypermethylation of Zygote Arrest 1 (ZAR1) in neuroblastomas.

Sugito K, Kawashima H, Yoshizawa S, Uekusa S, Hoshi R, Furuya T, Kaneda H, Hosoda T, Konuma N, Masuko T, Ohashi K, Ikeda T, Koshinaga T, Tomita R, Shinojima Y, Fujiwara K, Watanabe T, Held WA, Nagase H.

J Pediatr Surg. 2013 Apr;48(4):782-8. doi: 10.1016/j.jpedsurg.2012.08.008.

PMID:
23583134
2.

Identification of aberrant methylation regions in neuroblastoma by screening of tissue-specific differentially methylated regions.

Sugito K, Kawashima H, Uekusa S, Yoshizawa S, Hoshi R, Furuya T, Kaneda H, Hosoda T, Masuko T, Ohashi K, Ikeda T, Koshinaga T, Fujiwara K, Igarashi J, Ghosh S, Held WA, Nagase H.

Pediatr Blood Cancer. 2013 Mar;60(3):383-9. doi: 10.1002/pbc.24282. Epub 2012 Aug 21.

PMID:
22911660
3.

Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development.

Liang P, Song F, Ghosh S, Morien E, Qin M, Mahmood S, Fujiwara K, Igarashi J, Nagase H, Held WA.

BMC Genomics. 2011 May 11;12(1):231. doi: 10.1186/1471-2164-12-231.

4.

Epigenetic silencing of the kinase tumor suppressor WNK2 is tumor-type and tumor-grade specific.

Jun P, Hong C, Lal A, Wong JM, McDermott MW, Bollen AW, Plass C, Held WA, Smiraglia DJ, Costello JF.

Neuro Oncol. 2009 Aug;11(4):414-22. doi: 10.1215/15228517-2008-096. Epub 2008 Nov 11.

5.

Tissue specific differentially methylated regions (TDMR): Changes in DNA methylation during development.

Song F, Mahmood S, Ghosh S, Liang P, Smiraglia DJ, Nagase H, Held WA.

Genomics. 2009 Feb;93(2):130-9. doi: 10.1016/j.ygeno.2008.09.003. Epub 2008 Nov 13.

6.

Quantitative analysis of human tissue-specific differences in methylation.

Igarashi J, Muroi S, Kawashima H, Wang X, Shinojima Y, Kitamura E, Oinuma T, Nemoto N, Song F, Ghosh S, Held WA, Nagase H.

Biochem Biophys Res Commun. 2008 Nov 28;376(4):658-64. doi: 10.1016/j.bbrc.2008.09.044. Epub 2008 Sep 19.

7.

Identification of DNA methylation in 3' genomic regions that are associated with upregulation of gene expression in colorectal cancer.

Smith JF, Mahmood S, Song F, Morrow A, Smiraglia D, Zhang X, Rajput A, Higgins MJ, Krumm A, Petrelli NJ, Costello JF, Nagase H, Plass C, Held WA.

Epigenetics. 2007 Sep;2(3):161-72. Epub 2007 Jul 27.

8.

Analysis of tissue-specific differentially methylated regions (TDMs) in humans.

Kitamura E, Igarashi J, Morohashi A, Hida N, Oinuma T, Nemoto N, Song F, Ghosh S, Held WA, Yoshida-Noro C, Nagase H.

Genomics. 2007 Mar;89(3):326-37. Epub 2006 Dec 26.

9.

Association of tissue-specific differentially methylated regions (TDMs) with differential gene expression.

Song F, Smith JF, Kimura MT, Morrow AD, Matsuyama T, Nagase H, Held WA.

Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3336-41. Epub 2005 Feb 22.

10.

DNA methylation controls the responsiveness of hepatoma cells to leukemia inhibitory factor.

Blanchard F, Tracy E, Smith J, Chattopadhyay S, Wang Y, Held WA, Baumann H.

Hepatology. 2003 Dec;38(6):1516-28.

PMID:
14647063
11.

Global methylation screening in the Arabidopsis thaliana and Mus musculus genome: applications of virtual image restriction landmark genomic scanning (Vi-RLGS).

Matsuyama T, Kimura MT, Koike K, Abe T, Nakano T, Asami T, Ebisuzaki T, Held WA, Yoshida S, Nagase H.

Nucleic Acids Res. 2003 Aug 1;31(15):4490-6.

12.

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.

Carninci P, Waki K, Shiraki T, Konno H, Shibata K, Itoh M, Aizawa K, Arakawa T, Ishii Y, Sasaki D, Bono H, Kondo S, Sugahara Y, Saito R, Osato N, Fukuda S, Sato K, Watahiki A, Hirozane-Kishikawa T, Nakamura M, Shibata Y, Yasunishi A, Kikuchi N, Yoshiki A, Kusakabe M, Gustincich S, Beisel K, Pavan W, Aidinis V, Nakagawara A, Held WA, Iwata H, Kono T, Nakauchi H, Lyons P, Wells C, Hume DA, Fagiolini M, Hensch TK, Brinkmeier M, Camper S, Hirota J, Mombaerts P, Muramatsu M, Okazaki Y, Kawai J, Hayashizaki Y.

Genome Res. 2003 Jun;13(6B):1273-89.

13.

FR901228, an inhibitor of histone deacetylases, increases the cellular responsiveness to IL-6 type cytokines by enhancing the expression of receptor proteins.

Blanchard F, Kinzie E, Wang Y, Duplomb L, Godard A, Held WA, Asch BB, Baumann H.

Oncogene. 2002 Sep 12;21(41):6264-77.

14.

Excessive CpG island hypermethylation in cancer cell lines versus primary human malignancies.

Smiraglia DJ, Rush LJ, Frühwald MC, Dai Z, Held WA, Costello JF, Lang JC, Eng C, Li B, Wright FA, Caligiuri MA, Plass C.

Hum Mol Genet. 2001 Jun 15;10(13):1413-9.

15.

Novel methylation targets in de novo acute myeloid leukemia with prevalence of chromosome 11 loci.

Rush LJ, Dai Z, Smiraglia DJ, Gao X, Wright FA, Frühwald M, Costello JF, Held WA, Yu L, Krahe R, Kolitz JE, Bloomfield CD, Caligiuri MA, Plass C.

Blood. 2001 May 15;97(10):3226-33.

16.

Identification of a novel member of the snail/Gfi-1 repressor family, mlt 1, which is methylated and silenced in liver tumors of SV40 T antigen transgenic mice.

Tateno M, Fukunishi Y, Komatsu S, Okazaki Y, Kawai J, Shibata K, Itoh M, Muramatsu M, Held WA, Hayashizaki Y.

Cancer Res. 2001 Feb 1;61(3):1144-53.

17.

Restriction landmark genomic scanning of mouse liver tumors for gene amplification: overexpression of cyclin A2.

Haddad R, Morrow AD, Plass C, Held WA.

Biochem Biophys Res Commun. 2000 Jul 21;274(1):188-96.

PMID:
10903917
18.

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

Costello JF, Frühwald MC, Smiraglia DJ, Rush LJ, Robertson GP, Gao X, Wright FA, Feramisco JD, Peltomäki P, Lang JC, Schuller DE, Yu L, Bloomfield CD, Caligiuri MA, Yates A, Nishikawa R, Su Huang H, Petrelli NJ, Zhang X, O'Dorisio MS, Held WA, Cavenee WK, Plass C.

Nat Genet. 2000 Feb;24(2):132-8.

PMID:
10655057
19.

Methylation and downregulated expression of mac25/insulin-like growth factor binding protein-7 is associated with liver tumorigenesis in SV40T/t antigen transgenic mice, screened by restriction landmark genomic scanning for methylation (RLGS-M).

Komatsu S, Okazaki Y, Tateno M, Kawai J, Konno H, Kusakabe M, Yoshiki A, Muramatsu M, Held WA, Hayashizaki Y.

Biochem Biophys Res Commun. 2000 Jan 7;267(1):109-17.

PMID:
10623583
20.

Restriction landmark genome scanning for aberrant methylation in primary refractory and relapsed acute myeloid leukemia; involvement of the WIT-1 gene.

Plass C, Yu F, Yu L, Strout MP, El-Rifai W, Elonen E, Knuutila S, Marcucci G, Young DC, Held WA, Bloomfield CD, Caligiuri MA.

Oncogene. 1999 May 20;18(20):3159-65.

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