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Items: 20

1.

Development of tools for quantitative intracellular metabolomics of Aspergillus niger chemostat cultures.

Lameiras F, Heijnen JJ, van Gulik WM.

Metabolomics. 2015;11(5):1253-1264. Epub 2015 Feb 25.

2.

Determination of the Cytosolic NADPH/NADP Ratio in Saccharomyces cerevisiae using Shikimate Dehydrogenase as Sensor Reaction.

Zhang J, ten Pierick A, van Rossum HM, Seifar RM, Ras C, Daran JM, Heijnen JJ, Wahl SA.

Sci Rep. 2015 Aug 5;5:12846. doi: 10.1038/srep12846.

3.

Fast "Feast/Famine" Cycles for Studying Microbial Physiology Under Dynamic Conditions: A Case Study with Saccharomyces cerevisiae.

Suarez-Mendez CA, Sousa A, Heijnen JJ, Wahl A.

Metabolites. 2014 May 15;4(2):347-72. doi: 10.3390/metabo4020347.

4.

Glucose-methanol co-utilization in Pichia pastoris studied by metabolomics and instationary ¹³C flux analysis.

Jordà J, Suarez C, Carnicer M, ten Pierick A, Heijnen JJ, van Gulik W, Ferrer P, Albiol J, Wahl A.

BMC Syst Biol. 2013 Feb 28;7:17. doi: 10.1186/1752-0509-7-17.

5.

Similar temperature dependencies of glycolytic enzymes: an evolutionary adaptation to temperature dynamics?

Cruz LA, Hebly M, Duong GH, Wahl SA, Pronk JT, Heijnen JJ, Daran-Lapujade P, van Gulik WM.

BMC Syst Biol. 2012 Dec 7;6:151. doi: 10.1186/1752-0509-6-151.

6.

Substrate cycles in Penicillium chrysogenum quantified by isotopic non-stationary flux analysis.

Zhao Z, Ten Pierick A, de Jonge L, Heijnen JJ, Wahl SA.

Microb Cell Fact. 2012 Oct 25;11:140. doi: 10.1186/1475-2859-11-140.

7.

Optimization of cold methanol quenching for quantitative metabolomics of Penicillium chrysogenum.

de Jonge LP, Douma RD, Heijnen JJ, van Gulik WM.

Metabolomics. 2012 Aug;8(4):727-735. Epub 2011 Oct 7.

8.

Quantitative metabolomics analysis of amino acid metabolism in recombinant Pichia pastoris under different oxygen availability conditions.

Carnicer M, Ten Pierick A, van Dam J, Heijnen JJ, Albiol J, van Gulik W, Ferrer P.

Microb Cell Fact. 2012 Jun 15;11:83. doi: 10.1186/1475-2859-11-83.

9.

Development of quantitative metabolomics for Pichia pastoris.

Carnicer M, Canelas AB, Ten Pierick A, Zeng Z, van Dam J, Albiol J, Ferrer P, Heijnen JJ, van Gulik W.

Metabolomics. 2012 Apr;8(2):284-298. Epub 2011 Apr 21.

10.

pH-dependent uptake of fumaric acid in Saccharomyces cerevisiae under anaerobic conditions.

Jamalzadeh E, Verheijen PJ, Heijnen JJ, van Gulik WM.

Appl Environ Microbiol. 2012 Feb;78(3):705-16. doi: 10.1128/AEM.05591-11. Epub 2011 Nov 23.

11.

Degeneration of penicillin production in ethanol-limited chemostat cultivations of Penicillium chrysogenum: A systems biology approach.

Douma RD, Batista JM, Touw KM, Kiel JA, Krikken AM, Zhao Z, Veiga T, Klaassen P, Bovenberg RA, Daran JM, Heijnen JJ, van Gulik WM.

BMC Syst Biol. 2011 Aug 19;5:132. doi: 10.1186/1752-0509-5-132.

12.

Effect of iclR and arcA knockouts on biomass formation and metabolic fluxes in Escherichia coli K12 and its implications on understanding the metabolism of Escherichia coli BL21 (DE3).

Waegeman H, Beauprez J, Moens H, Maertens J, De Mey M, Foulquié-Moreno MR, Heijnen JJ, Charlier D, Soetaert W.

BMC Microbiol. 2011 Apr 11;11:70. doi: 10.1186/1471-2180-11-70.

13.

Cytosolic NADPH balancing in Penicillium chrysogenum cultivated on mixtures of glucose and ethanol.

Zhao Z, Kuijvenhoven K, van Gulik WM, Heijnen JJ, van Winden WA, Verheijen PJ.

Appl Microbiol Biotechnol. 2011 Jan;89(1):63-72. doi: 10.1007/s00253-010-2851-5. Epub 2010 Aug 31.

14.

Dynamics of glycolytic regulation during adaptation of Saccharomyces cerevisiae to fermentative metabolism.

van den Brink J, Canelas AB, van Gulik WM, Pronk JT, Heijnen JJ, de Winde JH, Daran-Lapujade P.

Appl Environ Microbiol. 2008 Sep;74(18):5710-23. doi: 10.1128/AEM.01121-08. Epub 2008 Jul 18.

15.
16.

When transcriptome meets metabolome: fast cellular responses of yeast to sudden relief of glucose limitation.

Kresnowati MT, van Winden WA, Almering MJ, ten Pierick A, Ras C, Knijnenburg TA, Daran-Lapujade P, Pronk JT, Heijnen JJ, Daran JM.

Mol Syst Biol. 2006;2:49. Epub 2006 Sep 12.

17.

Unlocking Streptomyces spp. for use as sustainable industrial production platforms by morphological engineering.

van Wezel GP, Krabben P, Traag BA, Keijser BJ, Kerste R, Vijgenboom E, Heijnen JJ, Kraal B.

Appl Environ Microbiol. 2006 Aug;72(8):5283-8. Erratum in: Appl Environ Microbiol. 2006 Oct;72(10):6863.

18.

13C-labeled gluconate tracing as a direct and accurate method for determining the pentose phosphate pathway split ratio in Penicillium chrysogenum.

Kleijn RJ, van Winden WA, Ras C, van Gulik WM, Schipper D, Heijnen JJ.

Appl Environ Microbiol. 2006 Jul;72(7):4743-54.

19.

Short-term metabolome dynamics and carbon, electron, and ATP balances in chemostat-grown Saccharomyces cerevisiae CEN.PK 113-7D following a glucose pulse.

Wu L, van Dam J, Schipper D, Kresnowati MT, Proell AM, Ras C, van Winden WA, van Gulik WM, Heijnen JJ.

Appl Environ Microbiol. 2006 May;72(5):3566-77.

20.

Glucose and the ATP paradox in yeast.

Somsen OJ, Hoeben MA, Esgalhado E, Snoep JL, Visser D, van der Heijden RT, Heijnen JJ, Westerhoff HV.

Biochem J. 2000 Dec 1;352 Pt 2:593-9.

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