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Assessing the Value of BMI and Aerobic Capacity as Surrogate Markers for the Severity of Left Ventricular Diastolic Dysfunction in Patients with Type 2 Diabetes Who Are Obese.

Smith C, Asrar Ul Haq M, Jerums G, Hanson E, Hayes A, Allen JD, Sbaraglia M, Selig S, Wong C, Hare DL, Levinger I.

Clin Med Insights Cardiol. 2016 May 12;10:61-5. doi: 10.4137/CMC.S38116. eCollection 2016.


Mitochondria: Inadvertent targets in chemotherapy-induced skeletal muscle toxicity and wasting?

Sorensen JC, Cheregi BD, Timpani CA, Nurgali K, Hayes A, Rybalka E.

Cancer Chemother Pharmacol. 2016 May 11. [Epub ahead of print] Review.


Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737).

Osborne JD, Matthews TP, McHardy T, Proisy N, Cheung KJ, Lainchbury M, Brown N, Walton MI, Eve PD, Boxall KJ, Hayes A, Henley AT, Valenti MR, De Haven Brandon AK, Box G, Jamin Y, Robinson SP, Westwood IM, van Montfort RL, Leonard PM, Lamers MB, Reader JC, Aherne GW, Raynaud FI, Eccles SA, Garrett MD, Collins I.

J Med Chem. 2016 May 23. [Epub ahead of print]


The role of emotion in learning trustworthiness from eye-gaze: Evidence from facial electromyography.

Manssuer LR, Pawling R, Hayes AE, Tipper SP.

Cogn Neurosci. 2016 Jan-Oct;7(1-4):82-102. doi: 10.1080/17588928.2015.1085374. Epub 2015 Oct 7.


Short and medium-term outcomes for general surgery in nonagenarian patients in a district general hospital.

Hayes AJ, Davda A, El-Hadi M, Murphy P, Papettas T.

Ann R Coll Surg Engl. 2016 May 3:1-4. [Epub ahead of print]


Isolated limb perfusion with biochemotherapy and oncolytic virotherapy combines with radiotherapy and surgery to overcome treatment resistance in an animal model of extremity soft tissue sarcoma.

Wilkinson MJ, Smith HG, Pencavel TD, Mansfield DC, Kyula-Currie J, Khan AA, McEntee G, Roulstone V, Hayes AJ, Harrington KJ.

Int J Cancer. 2016 Apr 26. doi: 10.1002/ijc.30162. [Epub ahead of print]


Sudden Gains in Cognitive-Behavior Therapy for Treatment-Resistant Depression: Processes of Change.

Abel A, Hayes AM, Henley W, Kuyken W.

J Consult Clin Psychol. 2016 Apr 21. [Epub ahead of print]


Development and external validation of two nomograms to predict overall survival and occurrence of distant metastases in adults after surgical resection of localised soft-tissue sarcomas of the extremities: a retrospective analysis.

Callegaro D, Miceli R, Bonvalot S, Ferguson P, Strauss DC, Levy A, Griffin A, Hayes AJ, Stacchiotti S, Pechoux CL, Smith MJ, Fiore M, Dei Tos AP, Smith HG, Mariani L, Wunder JS, Pollock RE, Casali PG, Gronchi A.

Lancet Oncol. 2016 Apr 5. pii: S1470-2045(16)00010-3. doi: 10.1016/S1470-2045(16)00010-3. [Epub ahead of print]


The CS Sulfation Motifs 4C3, 7D4, 3B3[-]; and Perlecan Identify Stem Cell Populations and Their Niches, Activated Progenitor Cells and Transitional Areas of Tissue Development in the Fetal Human Elbow.

Hayes AJ, Hughes CE, Smith SM, Caterson B, Little CB, Melrose J.

Stem Cells Dev. 2016 Jun 1;25(11):836-47. doi: 10.1089/scd.2016.0054. Epub 2016 May 5.


Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach.

Innocenti P, Woodward HL, Solanki S, Naud S, Westwood IM, Cronin N, Hayes A, Roberts J, Henley AT, Baker R, Faisal A, Mak GW, Box G, Valenti M, De Haven Brandon A, O'Fee L, Saville H, Schmitt J, Matijssen B, Burke R, van Montfort RL, Raynaud FI, Eccles SA, Linardopoulos S, Blagg J, Hoelder S.

J Med Chem. 2016 Apr 28;59(8):3671-88. doi: 10.1021/acs.jmedchem.5b01811. Epub 2016 Apr 7.


A study on the genetic relationships of Avena taxa and the origins of hexaploid oat.

Chew P, Meade K, Hayes A, Harjes C, Bao Y, Beattie AD, Puddephat I, Gusmini G, Tanksley SD.

Theor Appl Genet. 2016 Apr 5. [Epub ahead of print]


Giant intra-abdominal mature cystic teratoma (dermoid cyst) in an adult male, with male genitourinary tissue including prostatic and penile elements.

Thway K, Berney D, Hayes AJ, Fisher C.

Hum Pathol. 2016 Mar 30. pii: S0046-8177(16)30009-0. doi: 10.1016/j.humpath.2016.03.003. [Epub ahead of print]


Impact of multicellular tumor spheroids as an in vivo‑like tumor model on anticancer drug response.

Galateanu B, Hudita A, Negrei C, Ion RM, Costache M, Stan M, Nikitovic D, Hayes AW, Spandidos DA, Tsatsakis AM, Ginghina O.

Int J Oncol. 2016 Jun;48(6):2295-302. doi: 10.3892/ijo.2016.3467. Epub 2016 Apr 1.


Direct Evidence of Octupole Deformation in Neutron-Rich ^{144}Ba.

Bucher B, Zhu S, Wu CY, Janssens RV, Cline D, Hayes AB, Albers M, Ayangeakaa AD, Butler PA, Campbell CM, Carpenter MP, Chiara CJ, Clark JA, Crawford HL, Cromaz M, David HM, Dickerson C, Gregor ET, Harker J, Hoffman CR, Kay BP, Kondev FG, Korichi A, Lauritsen T, Macchiavelli AO, Pardo RC, Richard A, Riley MA, Savard G, Scheck M, Seweryniak D, Smith MK, Vondrasek R, Wiens A.

Phys Rev Lett. 2016 Mar 18;116(11):112503. doi: 10.1103/PhysRevLett.116.112503. Epub 2016 Mar 17.


Advancing Risk Assessment through the Application of Systems Toxicology.

Sauer JM, Kleensang A, Peitsch MC, Hayes AW.

Toxicol Res. 2016 Jan;32(1):5-8. doi: 10.5487/TR.2016.32.1.005. Epub 2016 Jan 31.


'Venus trapped, Mars transits': Cu and Fe redox chemistry, cellular topography and in situ ligand binding in terrestrial isopod hepatopancreas.

Kille P, Morgan AJ, Powell K, Mosselmans JF, Hart D, Gunning P, Hayes A, Scarborough D, McDonald I, Charnock JM.

Open Biol. 2016 Mar;6(3). pii: 150270. doi: 10.1098/rsob.150270.


Caffeine and cardiovascular diseases: critical review of current research.

Zulli A, Smith RM, Kubatka P, Novak J, Uehara Y, Loftus H, Qaradakhi T, Pohanka M, Kobyliak N, Zagatina A, Klimas J, Hayes A, La Rocca G, Soucek M, Kruzliak P.

Eur J Nutr. 2016 Jun;55(4):1331-43. doi: 10.1007/s00394-016-1179-z. Epub 2016 Mar 1. Review.


Resectable extra-pleural and extra-meningeal solitary fibrous tumours: A multi-centre prognostic study.

Pasquali S, Gronchi A, Strauss D, Bonvalot S, Jeys L, Stacchiotti S, Hayes A, Honore C, Collini P, Renne SL, Alexander N, Grimer RJ, Callegaro D, Sumathi VP, Gourevitch D, Desai A.

Eur J Surg Oncol. 2016 Feb 13. pii: S0748-7983(16)00093-7. doi: 10.1016/j.ejso.2016.01.023. [Epub ahead of print]


External validation of a multi-institutional retroperitoneal sarcoma nomogram.

Raut CP, Miceli R, Strauss DC, Swallow CJ, Hohenberger P, van Coevorden F, Rutkowski P, Fiore M, Callegaro D, Casali PG, Haas RL, Hayes AJ, Honore C, Cannell AJ, Jakob J, Szacht M, Fairweather M, Pollock RE, Bonvalot S, Gronchi A.

Cancer. 2016 May 1;122(9):1417-24. doi: 10.1002/cncr.29931. Epub 2016 Feb 24.


Elastofibroma dorsi: The clunking tumour that need not cause alarm.

Smith HG, Hannay J, Thway K, Messiou C, Smith M, Strauss DC, Hayes AJ.

Ann R Coll Surg Engl. 2016 Mar;98(3):208-11. doi: 10.1308/rcsann.2016.0064.

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