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Items: 1 to 20 of 243

1.
2.

A lipid nanoparticle for the efficient delivery of siRNA to dendritic cells.

Warashina S, Nakamura T, Sato Y, Fujiwara Y, Hyodo M, Hatakeyama H, Harashima H.

J Control Release. 2016 Jan 26;225:183-191. doi: 10.1016/j.jconrel.2016.01.042. [Epub ahead of print]

PMID:
26820519
3.

Telomere attrition and restoration in the normal teleost Oryzias latipes are linked to growth rate and telomerase activity at each life stage.

Hatakeyama H, Yamazaki H, Nakamura KI, Izumiyama-Shimomura N, Aida J, Suzuki H, Tsuchida S, Matsuura M, Takubo K, Ishikawa N.

Aging (Albany NY). 2016 Jan 20. [Epub ahead of print]

4.

Assessment of In Vivo siRNA Delivery in Cancer Mouse Models.

Hatakeyama H, Wu SY, Mangala LS, Lopez-Berestein G, Sood AK.

Methods Mol Biol. 2016;1402:189-97. doi: 10.1007/978-1-4939-3378-5_15.

PMID:
26721492
5.

Relationship Between the Physicochemical Properties of Lipid Nanoparticles and the Quality of siRNA Delivery to Liver Cells.

Sato Y, Hatakeyama H, Hyodo M, Harashima H.

Mol Ther. 2015 Dec 18. doi: 10.1038/mt.2015.222. [Epub ahead of print]

PMID:
26678452
6.

Novel pH-sensitive multifunctional envelope-type nanodevice for siRNA-based treatments for chronic HBV infection.

Yamamoto N, Sato Y, Munakata T, Kakuni M, Tateno C, Sanada T, Hirata Y, Murakami S, Tanaka Y, Chayama K, Hatakeyama H, Hyodo M, Harashima H, Kohara M.

J Hepatol. 2015 Oct 24. pii: S0168-8278(15)00713-8. doi: 10.1016/j.jhep.2015.10.014. [Epub ahead of print]

7.

Comparison of hearing outcomes after treatment for early-stage external auditory canal cancer.

Morita S, Nakamaru Y, Homma A, Sakashita T, Hatakeyama H, Masuya M, Fukuda S.

Head Neck. 2015 Oct 7. doi: 10.1002/hed.24168. [Epub ahead of print]

PMID:
26445914
8.

Size-dependent specific targeting and efficient gene silencing in peritoneal macrophages using a pH-sensitive cationic liposomal siRNA carrier.

Matsui H, Sato Y, Hatakeyama H, Akita H, Harashima H.

Int J Pharm. 2015 Nov 10;495(1):171-8. doi: 10.1016/j.ijpharm.2015.08.044. Epub 2015 Sep 7.

PMID:
26355712
9.

Molecular pathomechanisms and cell-type-specific disease phenotypes of MELAS caused by mutant mitochondrial tRNA(Trp).

Hatakeyama H, Katayama A, Komaki H, Nishino I, Goto Y.

Acta Neuropathol Commun. 2015 Aug 22;3:52. doi: 10.1186/s40478-015-0227-x.

10.

Decreased SMAD4 expression is associated with induction of epithelial-to-mesenchymal transition and cetuximab resistance in head and neck squamous cell carcinoma.

Cheng H, Fertig EJ, Ozawa H, Hatakeyama H, Howard JD, Perez J, Considine M, Thakar M, Ranaweera R, Krigsfeld G, Chung CH.

Cancer Biol Ther. 2015;16(8):1252-8. doi: 10.1080/15384047.2015.1056418. Epub 2015 Jun 5.

PMID:
26046389
11.

Mitochondrial respiratory dysfunction caused by a heteroplasmic mitochondrial DNA mutation blocks cellular reprogramming.

Yokota M, Hatakeyama H, Okabe S, Ono Y, Goto Y.

Hum Mol Genet. 2015 Aug 15;24(16):4698-709. doi: 10.1093/hmg/ddv201. Epub 2015 May 29.

PMID:
26025377
12.

[A clinical study of cases diagnosed as being oropharyngeal carcinoma after cervical mass extirpation/biopsy].

Mizumachi T, Kano S, Sakashita T, Hatakeyama H, Homma A, Fukuda S.

Nihon Jibiinkoka Gakkai Kaiho. 2014 Dec;117(12):1463-70. Japanese.

PMID:
25946828
13.

Voice Onset Time for the Word-Initial Voiceless Consonant /t/ in Japanese Spasmodic Dysphonia-A Comparison With Normal Controls.

Yanagida S, Nishizawa N, Mizoguchi K, Hatakeyama H, Fukuda S.

J Voice. 2015 Jul;29(4):450-4. doi: 10.1016/j.jvoice.2014.09.028. Epub 2015 May 2.

PMID:
25944292
14.

Multifunctional Envelope-Type Nano Device: Evolution from Nonselective to Active Targeting System.

Hayashi Y, Hatakeyama H, Kajimoto K, Hyodo M, Akita H, Harashima H.

Bioconjug Chem. 2015 Jul 15;26(7):1266-76. doi: 10.1021/acs.bioconjchem.5b00184. Epub 2015 Jun 5.

PMID:
25938819
15.

Indications for superselective intra-arterial cisplatin infusion and concomitant radiotherapy in cases of hypopharyngeal cancer.

Furusawa J, Homma A, Onimaru R, Sakashita T, Yoshida D, Hatakeyama H, Mizumachi T, Kano S, Tsuchiya K, Yasuda K, Shirato H, Fukuda S.

Auris Nasus Larynx. 2015 Dec;42(6):443-8. doi: 10.1016/j.anl.2015.04.003. Epub 2015 Apr 28.

PMID:
25933585
16.

The efficacy of superselective intra-arterial infusion with concomitant radiotherapy for adenoid cystic carcinoma of the head and neck.

Homma A, Sakashita T, Hatakeyama H, Kano S, Mizumachi T, Nakamaru Y, Yoshida D, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Fukuda S.

Acta Otolaryngol. 2015 Sep;135(9):950-4. doi: 10.3109/00016489.2015.1040171. Epub 2015 Apr 30.

PMID:
25925195
17.

Hangeshashinto improves the completion rate of chemoradiotherapy and the nutritional status in patients with head and neck cancer.

Hatakeyama H, Takahashi H, Oridate N, Kuramoto R, Fujiwara K, Homma A, Takeda H, Fukuda S.

ORL J Otorhinolaryngol Relat Spec. 2015;77(2):100-8. doi: 10.1159/000381026. Epub 2015 Apr 14.

PMID:
25896416
18.

Evaluation of a repeated-dose liver micronucleus assay with 2,6-dinitrotoluene using young adult rats.

Imamura T, Koeda A, Morimoto K, Hatakeyama H, Suzuki H, Wako Y, Kawasako K, Otabe K, Sato S.

Mutat Res Genet Toxicol Environ Mutagen. 2015 Mar;780-781:46-50. doi: 10.1016/j.mrgentox.2014.11.004. Epub 2014 Nov 20.

PMID:
25892621
19.

Olfactory neuroblastoma: the long-term outcome and late toxicity of multimodal therapy including radiotherapy based on treatment planning using computed tomography.

Mori T, Onimaru R, Onodera S, Tsuchiya K, Yasuda K, Hatakeyama H, Kobayashi H, Terasaka S, Homma A, Shirato H.

Radiat Oncol. 2015 Apr 15;10:88. doi: 10.1186/s13014-015-0397-5.

20.

Impaired respiratory function in MELAS-induced pluripotent stem cells with high heteroplasmy levels.

Kodaira M, Hatakeyama H, Yuasa S, Seki T, Egashira T, Tohyama S, Kuroda Y, Tanaka A, Okata S, Hashimoto H, Kusumoto D, Kunitomi A, Takei M, Kashimura S, Suzuki T, Yozu G, Shimojima M, Motoda C, Hayashiji N, Saito Y, Goto Y, Fukuda K.

FEBS Open Bio. 2015 Mar 20;5:219-25. doi: 10.1016/j.fob.2015.03.008. eCollection 2015.

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