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Results: 1 to 20 of 211

1.

Feasibility and efficacy of induction docetaxel, cisplatin, and 5-fluorouracil chemotherapy combined with concurrent weekly cisplatin chemoradiotherapy for locally advanced head and neck squamous cell carcinoma.

Mizumachi T, Homma A, Kakizaki T, Sakashita T, Kano S, Hatakeyama H, Tsuchiya K, Yasuda K, Onimaru R, Shirato H, Taguchi J, Shimizu Y, Kinoshita I, Akita H, Fukuda S.

Int J Clin Oncol. 2014 Jul 5. [Epub ahead of print]

PMID:
24993675
[PubMed - as supplied by publisher]
2.

An aptamer ligand based liposomal nanocarrier system that targets tumor endothelial cells.

Ara MN, Matsuda T, Hyodo M, Sakurai Y, Hatakeyama H, Ohga N, Hida K, Harashima H.

Biomaterials. 2014 Aug;35(25):7110-20. doi: 10.1016/j.biomaterials.2014.04.087. Epub 2014 May 27.

PMID:
24875764
[PubMed - in process]
3.

Improvement of Doxorubicin Efficacy Using Liposomal Anti-Polo-like Kinase 1 siRNA in Human Renal Cell Carcinomas.

Sakurai Y, Hatakeyama H, Akita H, Harashima H.

Mol Pharm. 2014 May 12. [Epub ahead of print]

PMID:
24800640
[PubMed - as supplied by publisher]
4.

In vivo therapeutic potential of Dicer-hunting siRNAs targeting infectious hepatitis C virus.

Watanabe T, Hatakeyama H, Matsuda-Yasui C, Sato Y, Sudoh M, Takagi A, Hirata Y, Ohtsuki T, Arai M, Inoue K, Harashima H, Kohara M.

Sci Rep. 2014 Apr 23;4:4750. doi: 10.1038/srep04750.

PMID:
24756133
[PubMed - in process]
Free PMC Article
5.

Hepatic Monoacylglycerol O-acyltransferase 1 as a Promising Therapeutic Target for Steatosis, Obesity, and Type 2 Diabetes.

Hayashi Y, Suemitsu E, Kajimoto K, Sato Y, Akhter A, Sakurai Y, Hatakeyama H, Hyodo M, Kaji N, Baba Y, Harashima H.

Mol Ther Nucleic Acids. 2014 Mar 18;3:e154. doi: 10.1038/mtna.2014.4.

PMID:
24643205
[PubMed]
Free PMC Article
6.

High level expression of AMAP1 protein correlates with poor prognosis and survival after surgery of head and neck squamous cell carcinoma patients.

Sato H, Hatanaka KC, Hatanaka Y, Hatakeyama H, Hashimoto A, Matsuno Y, Fukuda S, Sabe H.

Cell Commun Signal. 2014 Mar 12;12:17. doi: 10.1186/1478-811X-12-17.

PMID:
24621372
[PubMed - in process]
Free PMC Article
7.

2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity.

Wu SY, Yang X, Gharpure KM, Hatakeyama H, Egli M, McGuire MH, Nagaraja AS, Miyake TM, Rupaimoole R, Pecot CV, Taylor M, Pradeep S, Sierant M, Rodriguez-Aguayo C, Choi HJ, Previs RA, Armaiz-Pena GN, Huang L, Martinez C, Hassell T, Ivan C, Sehgal V, Singhania R, Han HD, Su C, Kim JH, Dalton HJ, Kovvali C, Keyomarsi K, McMillan NA, Overwijk WW, Liu J, Lee JS, Baggerly KA, Lopez-Berestein G, Ram PT, Nawrot B, Sood AK.

Nat Commun. 2014 Mar 12;5:3459. doi: 10.1038/ncomms4459.

PMID:
24619206
[PubMed - in process]
8.

Salvage operations for patients with persistent or recurrent cancer of the maxillary sinus after superselective intra-arterial infusion of cisplatin with concurrent radiotherapy.

Sakashita T, Homma A, Hatakeyama H, Kano S, Mizumachi T, Furusawa J, Yoshida D, Fujima N, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Suzuki F, Fukuda S.

Br J Oral Maxillofac Surg. 2014 Apr;52(4):323-8. doi: 10.1016/j.bjoms.2014.01.018. Epub 2014 Feb 26.

PMID:
24582012
[PubMed - in process]
9.

An apolipoprotein E modified liposomal nanoparticle: ligand dependent efficiency as a siRNA delivery carrier for mouse-derived brain endothelial cells.

Tamaru M, Akita H, Kajimoto K, Sato Y, Hatakeyama H, Harashima H.

Int J Pharm. 2014 Apr 25;465(1-2):77-82. doi: 10.1016/j.ijpharm.2014.02.016. Epub 2014 Feb 12.

PMID:
24530390
[PubMed - in process]
10.

The systemic administration of an anti-miRNA oligonucleotide encapsulated pH-sensitive liposome results in reduced level of hepatic microRNA-122 in mice.

Hatakeyama H, Murata M, Sato Y, Takahashi M, Minakawa N, Matsuda A, Harashima H.

J Control Release. 2013 Oct 25. pii: S0168-3659(13)00872-9. doi: 10.1016/j.jconrel.2013.10.023. [Epub ahead of print]

PMID:
24512791
[PubMed - as supplied by publisher]
11.

The systemic administration of an anti-miRNA oligonucleotide encapsulated pH-sensitive liposome results in reduced level of hepatic microRNA-122 in mice.

Hatakeyama H, Murata M, Sato Y, Takahashi M, Minakawa N, Matsuda A, Harashima H.

J Control Release. 2014 Jan 10;173:43-50.

PMID:
24511611
[PubMed - in process]
12.

Cancer multidrug resistance: mechanisms involved and strategies for circumvention using a drug delivery system.

Kibria G, Hatakeyama H, Harashima H.

Arch Pharm Res. 2014 Jan;37(1):4-15. doi: 10.1007/s12272-013-0276-2. Epub 2013 Nov 23.

PMID:
24272889
[PubMed - in process]
13.

The incidence of late neck recurrence in N0 maxillary sinus squamous cell carcinomas after superselective intra-arterial chemoradiotherapy without prophylactic neck irradiation.

Sakashita T, Homma A, Hatakeyama H, Kano S, Mizumachi T, Furusawa J, Yoshida D, Fujima N, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Fukuda S.

Eur Arch Otorhinolaryngol. 2013 Nov 9. [Epub ahead of print]

PMID:
24213278
[PubMed - as supplied by publisher]
14.

Superselective intra-arterial cisplatin infusion and concomitant radiotherapy for maxillary sinus cancer.

Homma A, Sakashita T, Yoshida D, Onimaru R, Tsuchiya K, Suzuki F, Yasuda K, Hatakeyama H, Furusawa J, Mizumachi T, Kano S, Inamura N, Taki S, Shirato H, Fukuda S.

Br J Cancer. 2013 Dec 10;109(12):2980-6. doi: 10.1038/bjc.2013.663. Epub 2013 Nov 5.

PMID:
24196792
[PubMed - indexed for MEDLINE]
15.

RNAi-mediated gene knockdown and anti-angiogenic therapy of RCCs using a cyclic RGD-modified liposomal-siRNA system.

Sakurai Y, Hatakeyama H, Sato Y, Hyodo M, Akita H, Ohga N, Hida K, Harashima H.

J Control Release. 2014 Jan 10;173:110-8. doi: 10.1016/j.jconrel.2013.10.003. Epub 2013 Oct 11.

PMID:
24120854
[PubMed - in process]
16.

Development of dual-color simultaneous single molecule imaging system for analyzing multiple intracellular trafficking activities.

Hatakeyama H, Kanzaki M.

Conf Proc IEEE Eng Med Biol Soc. 2013;2013:1418-21. doi: 10.1109/EMBC.2013.6609776.

PMID:
24109963
[PubMed - in process]
17.

In vitro optimization of 2'-OMe-4'-thioribonucleoside-modified anti-microRNA oligonucleotides and its targeting delivery to mouse liver using a liposomal nanoparticle.

Takahashi M, Yamada N, Hatakeyama H, Murata M, Sato Y, Minakawa N, Harashima H, Matsuda A.

Nucleic Acids Res. 2013 Dec;41(22):10659-67. doi: 10.1093/nar/gkt823. Epub 2013 Sep 11.

PMID:
24030710
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Efficacy of anthelmintic baiting of foxes against Echinococcus multilocularis in northern Japan.

Takahashi K, Uraguchi K, Hatakeyama H, Giraudoux P, Romig T.

Vet Parasitol. 2013 Nov 15;198(1-2):122-6. doi: 10.1016/j.vetpar.2013.08.006. Epub 2013 Aug 14.

PMID:
24001877
[PubMed - indexed for MEDLINE]
19.

Lipid envelope-type nanoparticle incorporating a multifunctional peptide for systemic siRNA delivery to the pulmonary endothelium.

Kusumoto K, Akita H, Ishitsuka T, Matsumoto Y, Nomoto T, Furukawa R, El-Sayed A, Hatakeyama H, Kajimoto K, Yamada Y, Kataoka K, Harashima H.

ACS Nano. 2013 Sep 24;7(9):7534-41. doi: 10.1021/nn401317t. Epub 2013 Aug 21.

PMID:
23909689
[PubMed - in process]
20.

Single quantum dot tracking reveals that an individual multivalent HIV-1 Tat protein transduction domain can activate machinery for lateral transport and endocytosis.

Suzuki Y, Roy CN, Promjunyakul W, Hatakeyama H, Gonda K, Imamura J, Vasudevanpillai B, Ohuchi N, Kanzaki M, Higuchi H, Kaku M.

Mol Cell Biol. 2013 Aug;33(15):3036-49. doi: 10.1128/MCB.01717-12. Epub 2013 Jun 3.

PMID:
23732912
[PubMed - indexed for MEDLINE]
Free PMC Article

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