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Results: 1 to 20 of 226

1.

Overexpression of Q-rich prion-like proteins suppresses polyQ cytotoxicity and alters the polyQ interactome.

Ripaud L, Chumakova V, Antonin M, Hastie AR, Pinkert S, Körner R, Ruff KM, Pappu RV, Hornburg D, Mann M, Hartl FU, Hipp MS.

Proc Natl Acad Sci U S A. 2014 Dec 8. pii: 201421313. [Epub ahead of print]

PMID:
25489109
[PubMed - as supplied by publisher]
Free Article
2.

Role of Small Subunit in Mediating Assembly of Red-type Form 1 Rubisco.

Joshi J, Mueller-Cajar O, Tsai YC, Hartl FU, Hayer-Hartl M.

J Biol Chem. 2014 Nov 4. pii: jbc.M114.613091. [Epub ahead of print]

PMID:
25371207
[PubMed - as supplied by publisher]
Free Article
3.

Proteostasis impairment in protein-misfolding and -aggregation diseases.

Hipp MS, Park SH, Hartl FU.

Trends Cell Biol. 2014 Sep;24(9):506-14. doi: 10.1016/j.tcb.2014.05.003. Epub 2014 Jun 16.

PMID:
24946960
[PubMed - in process]
4.

Active cage mechanism of chaperonin-assisted protein folding demonstrated at single-molecule level.

Gupta AJ, Haldar S, Miličić G, Hartl FU, Hayer-Hartl M.

J Mol Biol. 2014 Jul 29;426(15):2739-54. doi: 10.1016/j.jmb.2014.04.018. Epub 2014 May 6.

PMID:
24816391
[PubMed - indexed for MEDLINE]
5.

GroEL/ES chaperonin modulates the mechanism and accelerates the rate of TIM-barrel domain folding.

Georgescauld F, Popova K, Gupta AJ, Bracher A, Engen JR, Hayer-Hartl M, Hartl FU.

Cell. 2014 May 8;157(4):922-34. doi: 10.1016/j.cell.2014.03.038.

PMID:
24813614
[PubMed - indexed for MEDLINE]
6.

Sugarcoating ER Stress.

Vincenz L, Hartl FU.

Cell. 2014 Mar 13;156(6):1125-7. doi: 10.1016/j.cell.2014.02.035.

PMID:
24630714
[PubMed - indexed for MEDLINE]
7.

ER stress-induced eIF2-alpha phosphorylation underlies sensitivity of striatal neurons to pathogenic huntingtin.

Leitman J, Barak B, Benyair R, Shenkman M, Ashery U, Hartl FU, Lederkremer GZ.

PLoS One. 2014 Mar 3;9(3):e90803. doi: 10.1371/journal.pone.0090803. eCollection 2014.

PMID:
24594939
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Interplay of acetyltransferase EP300 and the proteasome system in regulating heat shock transcription factor 1.

Raychaudhuri S, Loew C, Körner R, Pinkert S, Theis M, Hayer-Hartl M, Buchholz F, Hartl FU.

Cell. 2014 Feb 27;156(5):975-85. doi: 10.1016/j.cell.2014.01.055.

PMID:
24581496
[PubMed - indexed for MEDLINE]
9.

The first chaperonin.

Hartl FU, Hayer-Hartl M.

Nat Rev Mol Cell Biol. 2013 Oct;14(10):611. doi: 10.1038/nrm3665. No abstract available.

PMID:
24061226
[PubMed - indexed for MEDLINE]
10.

Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle.

Li Z, Hartl FU, Bracher A.

Nat Struct Mol Biol. 2013 Aug;20(8):929-35. doi: 10.1038/nsmb.2608. Epub 2013 Jun 30.

PMID:
23812373
[PubMed - indexed for MEDLINE]
11.

PolyQ proteins interfere with nuclear degradation of cytosolic proteins by sequestering the Sis1p chaperone.

Park SH, Kukushkin Y, Gupta R, Chen T, Konagai A, Hipp MS, Hayer-Hartl M, Hartl FU.

Cell. 2013 Jul 3;154(1):134-45. doi: 10.1016/j.cell.2013.06.003. Epub 2013 Jun 20.

PMID:
23791384
[PubMed - indexed for MEDLINE]
Free Article
12.

Molecular chaperone functions in protein folding and proteostasis.

Kim YE, Hipp MS, Bracher A, Hayer-Hartl M, Hartl FU.

Annu Rev Biochem. 2013;82:323-55. doi: 10.1146/annurev-biochem-060208-092442. Review.

PMID:
23746257
[PubMed - indexed for MEDLINE]
13.

Folding of large multidomain proteins by partial encapsulation in the chaperonin TRiC/CCT.

Rüßmann F, Stemp MJ, Mönkemeyer L, Etchells SA, Bracher A, Hartl FU.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21208-15. doi: 10.1073/pnas.1218836109. Epub 2012 Nov 28.

PMID:
23197838
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Structural probing of a protein phosphatase 2A network by chemical cross-linking and mass spectrometry.

Herzog F, Kahraman A, Boehringer D, Mak R, Bracher A, Walzthoeni T, Leitner A, Beck M, Hartl FU, Ban N, Malmström L, Aebersold R.

Science. 2012 Sep 14;337(6100):1348-52. doi: 10.1126/science.1221483.

PMID:
22984071
[PubMed - indexed for MEDLINE]
Free Article
15.

DnaK functions as a central hub in the E. coli chaperone network.

Calloni G, Chen T, Schermann SM, Chang HC, Genevaux P, Agostini F, Tartaglia GG, Hayer-Hartl M, Hartl FU.

Cell Rep. 2012 Mar 29;1(3):251-64. doi: 10.1016/j.celrep.2011.12.007. Epub 2012 Mar 8.

PMID:
22832197
[PubMed - indexed for MEDLINE]
Free Article
16.

Chaperonin cofactors, Cpn10 and Cpn20, of green algae and plants function as hetero-oligomeric ring complexes.

Tsai YC, Mueller-Cajar O, Saschenbrecker S, Hartl FU, Hayer-Hartl M.

J Biol Chem. 2012 Jun 8;287(24):20471-81. doi: 10.1074/jbc.M112.365411. Epub 2012 Apr 19.

PMID:
22518837
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The molecular architecture of the eukaryotic chaperonin TRiC/CCT.

Leitner A, Joachimiak LA, Bracher A, Mönkemeyer L, Walzthoeni T, Chen B, Pechmann S, Holmes S, Cong Y, Ma B, Ludtke S, Chiu W, Hartl FU, Aebersold R, Frydman J.

Structure. 2012 May 9;20(5):814-25. doi: 10.1016/j.str.2012.03.007. Epub 2012 Apr 12.

PMID:
22503819
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Advancing cell biology through proteomics in space and time (PROSPECTS).

Lamond AI, Uhlen M, Horning S, Makarov A, Robinson CV, Serrano L, Hartl FU, Baumeister W, Werenskiold AK, Andersen JS, Vorm O, Linial M, Aebersold R, Mann M.

Mol Cell Proteomics. 2012 Mar;11(3):O112.017731. doi: 10.1074/mcp.O112.017731. Epub 2012 Feb 6.

PMID:
22311636
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Quantitative proteomics reveals that Hsp90 inhibition preferentially targets kinases and the DNA damage response.

Sharma K, Vabulas RM, Macek B, Pinkert S, Cox J, Mann M, Hartl FU.

Mol Cell Proteomics. 2012 Mar;11(3):M111.014654. doi: 10.1074/mcp.M111.014654. Epub 2011 Dec 13.

PMID:
22167270
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Structure of green-type Rubisco activase from tobacco.

Stotz M, Mueller-Cajar O, Ciniawsky S, Wendler P, Hartl FU, Bracher A, Hayer-Hartl M.

Nat Struct Mol Biol. 2011 Nov 6;18(12):1366-70. doi: 10.1038/nsmb.2171.

PMID:
22056769
[PubMed - indexed for MEDLINE]

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