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Results: 1 to 20 of 71

1.

Rescuing US biomedical research from its systemic flaws.

Alberts B, Kirschner MW, Tilghman S, Varmus H.

Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):5773-7. doi: 10.1073/pnas.1404402111. Epub 2014 Apr 14.

PMID:
24733905
[PubMed - indexed for MEDLINE]
2.

The Art and Politics of Science.

Varmus H.

New York: W.W. Norton & Company; 2009.

PMID:
24696889
[PubMed]
Books & Documents
3.

Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer.

de Bruin EC, Cowell C, Warne PH, Jiang M, Saunders RE, Melnick MA, Gettinger S, Walther Z, Wurtz A, Heynen GJ, Heideman DA, Gómez-Román J, García-Castaño A, Gong Y, Ladanyi M, Varmus H, Bernards R, Smit EF, Politi K, Downward J.

Cancer Discov. 2014 May;4(5):606-19. doi: 10.1158/2159-8290.CD-13-0741. Epub 2014 Feb 17.

PMID:
24535670
[PubMed - in process]
4.

DOK2 inhibits EGFR-mutated lung adenocarcinoma.

Berger AH, Chen M, Morotti A, Janas JA, Niki M, Bronson RT, Taylor BS, Ladanyi M, Van Aelst L, Politi K, Varmus HE, Pandolfi PP.

PLoS One. 2013 Nov 8;8(11):e79526. doi: 10.1371/journal.pone.0079526. eCollection 2013.

PMID:
24255704
[PubMed - in process]
Free PMC Article
5.

Addressing the growing international challenge of cancer: a multinational perspective.

Varmus H, Kumar HS.

Sci Transl Med. 2013 Mar 6;5(175):175cm2. doi: 10.1126/scitranslmed.3005899.

PMID:
23467558
[PubMed - indexed for MEDLINE]
6.

Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins.

Lockwood WW, Zejnullahu K, Bradner JE, Varmus H.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19408-13. doi: 10.1073/pnas.1216363109. Epub 2012 Nov 5.

PMID:
23129625
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Three decades of Wnts: a personal perspective on how a scientific field developed.

Nusse R, Varmus H.

EMBO J. 2012 Jun 13;31(12):2670-84. doi: 10.1038/emboj.2012.146. Epub 2012 May 22. Review.

PMID:
22617420
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A conversation with Harold Varmus. Interview by Ushma S. Neill.

Varmus H.

J Clin Invest. 2012 Apr 2;122(4):1134-5. No abstract available.

PMID:
22570861
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Science funding: Provocative questions in cancer research.

Varmus H, Harlow E.

Nature. 2012 Jan 25;481(7382):436-7. doi: 10.1038/481436a. No abstract available.

PMID:
22281578
[PubMed - indexed for MEDLINE]
10.

Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1.

Beverly LJ, Lockwood WW, Shah PP, Erdjument-Bromage H, Varmus H.

Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):E119-26. doi: 10.1073/pnas.1119167109. Epub 2012 Jan 10.

PMID:
22233804
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Epstein-Barr virus: an important vaccine target for cancer prevention.

Cohen JI, Fauci AS, Varmus H, Nabel GJ.

Sci Transl Med. 2011 Nov 2;3(107):107fs7. doi: 10.1126/scitranslmed.3002878.

PMID:
22049067
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Receptor for hyaluronan-mediated motility isoform B promotes liver metastasis in a mouse model of multistep tumorigenesis and a tail vein assay for metastasis.

Du YC, Chou CK, Klimstra DS, Varmus H.

Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16753-8. doi: 10.1073/pnas.1114022108. Epub 2011 Sep 21.

PMID:
21940500
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Integrating cancer control into global health.

Varmus H, Trimble EL.

Sci Transl Med. 2011 Sep 21;3(101):101cm28. doi: 10.1126/scitranslmed.3002321. Review.

PMID:
21937755
[PubMed - indexed for MEDLINE]
14.

Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines.

Somwar R, Erdjument-Bromage H, Larsson E, Shum D, Lockwood WW, Yang G, Sander C, Ouerfelli O, Tempst PJ, Djaballah H, Varmus HE.

Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16375-80. doi: 10.1073/pnas.1113554108. Epub 2011 Sep 19.

PMID:
21930909
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Lung cancer signatures in plasma based on proteome profiling of mouse tumor models.

Taguchi A, Politi K, Pitteri SJ, Lockwood WW, Faça VM, Kelly-Spratt K, Wong CH, Zhang Q, Chin A, Park KS, Goodman G, Gazdar AF, Sage J, Dinulescu DM, Kucherlapati R, Depinho RA, Kemp CJ, Varmus HE, Hanash SM.

Cancer Cell. 2011 Sep 13;20(3):289-99. doi: 10.1016/j.ccr.2011.08.007.

PMID:
21907921
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Newsmaker interview: Harold Varmus. Piloting cancer research with a shrinking budget. Interview by Jocelyn Kaiser.

Varmus H.

Science. 2011 Jul 22;333(6041):397. doi: 10.1126/science.333.6041.397. No abstract available.

PMID:
21778374
[PubMed - indexed for MEDLINE]
17.

NIH cancer chief wants more with less: by Meredith Wadman.

Varmus H.

Nature. 2011 Jul 6;475(7354):18. doi: 10.1038/475018a. No abstract available.

PMID:
21734681
[PubMed - indexed for MEDLINE]
18.

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.

Barretina J, Taylor BS, Banerji S, Ramos AH, Lagos-Quintana M, Decarolis PL, Shah K, Socci ND, Weir BA, Ho A, Chiang DY, Reva B, Mermel CH, Getz G, Antipin Y, Beroukhim R, Major JE, Hatton C, Nicoletti R, Hanna M, Sharpe T, Fennell TJ, Cibulskis K, Onofrio RC, Saito T, Shukla N, Lau C, Nelander S, Silver SJ, Sougnez C, Viale A, Winckler W, Maki RG, Garraway LA, Lash A, Greulich H, Root DE, Sellers WR, Schwartz GK, Antonescu CR, Lander ES, Varmus HE, Ladanyi M, Sander C, Meyerson M, Singer S.

Nat Genet. 2010 Aug;42(8):715-21. doi: 10.1038/ng.619. Epub 2010 Jul 4.

PMID:
20601955
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Ten years on--the human genome and medicine.

Varmus H.

N Engl J Med. 2010 May 27;362(21):2028-9. doi: 10.1056/NEJMe0911933. No abstract available.

PMID:
20505183
[PubMed - indexed for MEDLINE]
Free Article
20.

Erlotinib resistance in mouse models of epidermal growth factor receptor-induced lung adenocarcinoma.

Politi K, Fan PD, Shen R, Zakowski M, Varmus H.

Dis Model Mech. 2010 Jan-Feb;3(1-2):111-9. doi: 10.1242/dmm.003681. Epub 2009 Dec 9.

PMID:
20007486
[PubMed - indexed for MEDLINE]
Free PMC Article

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