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Results: 7

1.

CNX-013-B2, a unique pan tissue acting rexinoid, modulates several nuclear receptors and controls multiple risk factors of the metabolic syndrome without risk of hypertriglyceridemia, hepatomegaly and body weight gain in animal models.

Sadasivuni MK, Reddy BM, Singh J, Anup MO, Sunil V, Lakshmi MN, Yogeshwari S, Chacko SK, Pooja TL, Dandu A, Harish C, Gopala AS, Pratibha S, Naveenkumar BS, Pallavi PM, Verma MK, Moolemath Y, Somesh BP, Venkataranganna MV, Jagannath MR.

Diabetol Metab Syndr. 2014 Aug 12;6(1):83. doi: 10.1186/1758-5996-6-83. eCollection 2014.

PMID:
25143786
[PubMed]
Free PMC Article
2.

A novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potential to provide cardio protective benefits.

Anil TM, Dandu A, Harsha K, Singh J, Shree N, Kumar VS, Lakshmi MN, Sunil V, Harish C, Balamurali GV, Naveen Kumar BS, Gopala AS, Pratibha S, Sadasivuni M, Anup MO, Moolemath Y, Venkataranganna MV, Jagannath MR, Somesh BP.

BMC Pharmacol Toxicol. 2014 Aug 7;15:43. doi: 10.1186/2050-6511-15-43.

PMID:
25098735
[PubMed - in process]
Free PMC Article
3.

CNX-012-570, a direct AMPK activator provides strong glycemic and lipid control along with significant reduction in body weight; studies from both diet-induced obese mice and db/db mice models.

Anil TM, Harish C, Lakshmi MN, Harsha K, Onkaramurthy M, Sathish Kumar V, Shree N, Geetha V, Balamurali GV, Gopala AS, Madhusudhan Reddy B, Govind MK, Anup MO, Moolemath Y, Venkataranganna MV, Jagannath MR, Somesh BP.

Cardiovasc Diabetol. 2014 Jan 25;13:27. doi: 10.1186/1475-2840-13-27.

PMID:
24460834
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Rimonabant for prevention of cardiovascular events (CRESCENDO): a randomised, multicentre, placebo-controlled trial.

Topol EJ, Bousser MG, Fox KA, Creager MA, Despres JP, Easton JD, Hamm CW, Montalescot G, Steg PG, Pearson TA, Cohen E, Gaudin C, Job B, Murphy JH, Bhatt DL; CRESCENDO Investigators.

Lancet. 2010 Aug 14;376(9740):517-23. doi: 10.1016/S0140-6736(10)60935-X.

PMID:
20709233
[PubMed - indexed for MEDLINE]
5.
6.

Anti-cancer effect of Cassia auriculata leaf extract in vitro through cell cycle arrest and induction of apoptosis in human breast and larynx cancer cell lines.

Prasanna R, Harish CC, Pichai R, Sakthisekaran D, Gunasekaran P.

Cell Biol Int. 2009 Feb;33(2):127-34. doi: 10.1016/j.cellbi.2008.10.006. Epub 2008 Nov 1.

PMID:
18996213
[PubMed - indexed for MEDLINE]
7.

Case report on clopidogrel rash after coronary placement of a paclitaxol-coated stent.

Satish B, Tressa K, Harish CR.

Crit Pathw Cardiol. 2007 Mar;6(1):24-5.

PMID:
17667883
[PubMed - indexed for MEDLINE]
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