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Results: 1 to 20 of 130

1.

Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis.

Pimkin M, Kossenkov AV, Mishra T, Morrissey CS, Wu W, Keller CA, Blobel GA, Lee D, Beer MA, Hardison RC, Weiss MJ.

Genome Res. 2014 Oct 15. pii: gr.164178.113. [Epub ahead of print]

PMID:
25319996
[PubMed - as supplied by publisher]
Free Article
2.

Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis.

Wu W, Morrissey CS, Keller CA, Mishra T, Pimkin M, Blobel GA, Weiss MJ, Hardison RC.

Genome Res. 2014 Oct 15. pii: gr.164830.113. [Epub ahead of print]

PMID:
25319994
[PubMed - as supplied by publisher]
Free Article
3.

Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease.

Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos J, Weng Z, White KP, Hardison RC.

Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):E3366. No abstract available.

PMID:
25275169
[PubMed - in process]
4.

A comprehensive and high-resolution genome-wide response of p53 to stress.

Chang GS, Chen XA, Park B, Rhee HS, Li P, Han KH, Mishra T, Chan-Salis KY, Li Y, Hardison RC, Wang Y, Pugh BF.

Cell Rep. 2014 Jul 24;8(2):514-27. doi: 10.1016/j.celrep.2014.06.030. Epub 2014 Jul 17.

PMID:
25043190
[PubMed - in process]
Free Article
5.

Discovering enhancers directly by activity.

Hardison RC.

Nat Methods. 2014 May;11(5):491-2. doi: 10.1038/nmeth.2933. No abstract available.

PMID:
24781321
[PubMed - indexed for MEDLINE]
6.

Defining functional DNA elements in the human genome.

Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos JA, Weng Z, White KP, Hardison RC.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6131-8. doi: 10.1073/pnas.1318948111. Epub 2014 Apr 21. Review.

PMID:
24753594
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

MRHMMs: multivariate regression hidden Markov models and the variantS.

Lee Y, Ghosh D, Hardison RC, Zhang Y.

Bioinformatics. 2014 Jun 15;30(12):1755-6. doi: 10.1093/bioinformatics/btu070. Epub 2014 Feb 19.

PMID:
24558116
[PubMed - indexed for MEDLINE]
8.

Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development.

Paralkar VR, Mishra T, Luan J, Yao Y, Kossenkov AV, Anderson SM, Dunagin M, Pimkin M, Gore M, Sun D, Konuthula N, Raj A, An X, Mohandas N, Bodine DM, Hardison RC, Weiss MJ.

Blood. 2014 Mar 20;123(12):1927-37. doi: 10.1182/blood-2013-12-544494. Epub 2014 Feb 4.

PMID:
24497530
[PubMed - indexed for MEDLINE]
9.

Function of GATA factors in the adult mouse liver.

Zheng R, Rebolledo-Jaramillo B, Zong Y, Wang L, Russo P, Hancock W, Stanger BZ, Hardison RC, Blobel GA.

PLoS One. 2013 Dec 18;8(12):e83723. doi: 10.1371/journal.pone.0083723. eCollection 2013.

PMID:
24367609
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Integrating and mining the chromatin landscape of cell-type specificity using self-organizing maps.

Mortazavi A, Pepke S, Jansen C, Marinov GK, Ernst J, Kellis M, Hardison RC, Myers RM, Wold BJ.

Genome Res. 2013 Dec;23(12):2136-48. doi: 10.1101/gr.158261.113. Epub 2013 Oct 29.

PMID:
24170599
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Updates of the HbVar database of human hemoglobin variants and thalassemia mutations.

Giardine B, Borg J, Viennas E, Pavlidis C, Moradkhani K, Joly P, Bartsakoulia M, Riemer C, Miller W, Tzimas G, Wajcman H, Hardison RC, Patrinos GP.

Nucleic Acids Res. 2014 Jan;42(Database issue):D1063-9. doi: 10.1093/nar/gkt911. Epub 2013 Oct 16.

PMID:
24137000
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Genetics. GWAS to therapy by genome edits?

Hardison RC, Blobel GA.

Science. 2013 Oct 11;342(6155):206-7. doi: 10.1126/science.1245813. No abstract available.

PMID:
24115432
[PubMed - indexed for MEDLINE]
13.

A cluster to remember.

Blobel GA, Hardison RC.

Cell. 2013 Aug 15;154(4):718-20. doi: 10.1016/j.cell.2013.07.041.

PMID:
23953105
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Identification of biologically relevant enhancers in human erythroid cells.

Su MY, Steiner LA, Bogardus H, Mishra T, Schulz VP, Hardison RC, Gallagher PG.

J Biol Chem. 2013 Mar 22;288(12):8433-44. doi: 10.1074/jbc.M112.413260. Epub 2013 Jan 22.

PMID:
23341446
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Integrative annotation of chromatin elements from ENCODE data.

Hoffman MM, Ernst J, Wilder SP, Kundaje A, Harris RS, Libbrecht M, Giardine B, Ellenbogen PM, Bilmes JA, Birney E, Hardison RC, Dunham I, Kellis M, Noble WS.

Nucleic Acids Res. 2013 Jan;41(2):827-41. doi: 10.1093/nar/gks1284. Epub 2012 Dec 5.

PMID:
23221638
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Evolution of hemoglobin and its genes.

Hardison RC.

Cold Spring Harb Perspect Med. 2012 Dec 1;2(12):a011627. doi: 10.1101/cshperspect.a011627.

PMID:
23209182
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells.

Chou ST, Byrska-Bishop M, Tober JM, Yao Y, Vandorn D, Opalinska JB, Mills JA, Choi JK, Speck NA, Gadue P, Hardison RC, Nemiroff RL, French DL, Weiss MJ.

Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17573-8. doi: 10.1073/pnas.1211175109. Epub 2012 Oct 8.

PMID:
23045704
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Genome-wide epigenetic data facilitate understanding of disease susceptibility association studies.

Hardison RC.

J Biol Chem. 2012 Sep 7;287(37):30932-40. doi: 10.1074/jbc.R112.352427. Epub 2012 Sep 5. Review.

PMID:
22952232
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1.

Kadauke S, Udugama MI, Pawlicki JM, Achtman JC, Jain DP, Cheng Y, Hardison RC, Blobel GA.

Cell. 2012 Aug 17;150(4):725-37. doi: 10.1016/j.cell.2012.06.038.

PMID:
22901805
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Genomic approaches towards finding cis-regulatory modules in animals.

Hardison RC, Taylor J.

Nat Rev Genet. 2012 Jun 18;13(7):469-83. doi: 10.1038/nrg3242. Review.

PMID:
22705667
[PubMed - indexed for MEDLINE]
Free PMC Article

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