Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 71

1.

Ionotropic GABA and glycine receptor subunit composition in human pluripotent stem cell-derived excitatory cortical neurones.

James OT, Livesey MR, Qiu J, Dando O, Bilican B, Haghi G, Rajan R, Burr K, Hardingham GE, Chandran S, Kind PC, Wyllie DJ.

J Physiol. 2014 Aug 28. [Epub ahead of print]

PMID:
25172951
[PubMed - as supplied by publisher]
2.

Nrf2 target genes can be controlled by neuronal activity in the absence of Nrf2 and astrocytes.

Deighton RF, Márkus NM, Al-Mubarak B, Bell KF, Papadia S, Meakin PJ, Chowdhry S, Hayes JD, Hardingham GE.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):E1818-20. doi: 10.1073/pnas.1402097111. Epub 2014 Apr 21. No abstract available.

PMID:
24753562
[PubMed - indexed for MEDLINE]
3.

Maturation of AMPAR composition and the GABAAR reversal potential in hPSC-derived cortical neurons.

Livesey MR, Bilican B, Qiu J, Rzechorzek NM, Haghi G, Burr K, Hardingham GE, Chandran S, Wyllie DJ.

J Neurosci. 2014 Mar 12;34(11):4070-5. doi: 10.1523/JNEUROSCI.5410-13.2014.

PMID:
24623784
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Physiological normoxia and absence of EGF is required for the long-term propagation of anterior neural precursors from human pluripotent cells.

Bilican B, Livesey MR, Haghi G, Qiu J, Burr K, Siller R, Hardingham GE, Wyllie DJ, Chandran S.

PLoS One. 2014 Jan 17;9(1):e85932. doi: 10.1371/journal.pone.0085932. eCollection 2014.

PMID:
24465796
[PubMed - in process]
Free PMC Article
5.

Phosphoinositide 3-kinases upregulate system xc(-) via eukaryotic initiation factor 2α and activating transcription factor 4 - A pathway active in glioblastomas and epilepsy.

Lewerenz J, Baxter P, Kassubek R, Albrecht P, Van Liefferinge J, Westhoff MA, Halatsch ME, Karpel-Massler G, Meakin PJ, Hayes JD, Aronica E, Smolders I, Ludolph AC, Methner A, Conrad M, Massie A, Hardingham GE, Maher P.

Antioxid Redox Signal. 2014 Jun 20;20(18):2907-22. doi: 10.1089/ars.2013.5455. Epub 2014 Feb 6.

PMID:
24219064
[PubMed - in process]
6.

Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals.

Qiu J, Tan YW, Hagenston AM, Martel MA, Kneisel N, Skehel PA, Wyllie DJ, Bading H, Hardingham GE.

Nat Commun. 2013;4:2034. doi: 10.1038/ncomms3034.

PMID:
23774321
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".

Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, Wilmut I, Finkbeiner S, Maniatis T, Shaw CE, Chandran S.

Sci Transl Med. 2013 Jun 5;5(188):188le2. doi: 10.1126/scitranslmed.3005065.

PMID:
23740897
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

NMDA receptor-dependent glutamate excitotoxicity in human embryonic stem cell-derived neurons.

Gupta K, Hardingham GE, Chandran S.

Neurosci Lett. 2013 May 24;543:95-100. doi: 10.1016/j.neulet.2013.03.010. Epub 2013 Mar 18.

PMID:
23518152
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Recovery of NMDA receptor currents from MK-801 blockade is accelerated by Mg2+ and memantine under conditions of agonist exposure.

McKay S, Bengtson CP, Bading H, Wyllie DJ, Hardingham GE.

Neuropharmacology. 2013 Nov;74:119-25. doi: 10.1016/j.neuropharm.2013.01.024. Epub 2013 Feb 10.

PMID:
23402996
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Influence of GluN2 subunit identity on NMDA receptor function.

Wyllie DJ, Livesey MR, Hardingham GE.

Neuropharmacology. 2013 Nov;74:4-17. doi: 10.1016/j.neuropharm.2013.01.016. Epub 2013 Jan 31. Review.

PMID:
23376022
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Human stem cell-derived astrocytes and their application to studying Nrf2-mediated neuroprotective pathways and therapeutics in neurodegeneration.

Gupta K, Chandran S, Hardingham GE.

Br J Clin Pharmacol. 2013 Apr;75(4):907-18. doi: 10.1111/bcp.12022. Review.

PMID:
23126226
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

SMRT-mediated co-shuttling enables export of class IIa HDACs independent of their CaM kinase phosphorylation sites.

Soriano FX, Chawla S, Skehel P, Hardingham GE.

J Neurochem. 2013 Jan;124(1):26-35. doi: 10.1111/jnc.12058. Epub 2012 Nov 15.

PMID:
23083128
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Ablation of PGC1 beta prevents mTOR dependent endoplasmic reticulum stress response.

Camacho A, Rodriguez-Cuenca S, Blount M, Prieur X, Barbarroja N, Fuller M, Hardingham GE, Vidal-Puig A.

Exp Neurol. 2012 Oct;237(2):396-406. doi: 10.1016/j.expneurol.2012.06.031. Epub 2012 Jul 6. Erratum in: Exp Neurol. 2013 Jan;239:101.

PMID:
22771762
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

SynGAP isoforms exert opposing effects on synaptic strength.

McMahon AC, Barnett MW, O'Leary TS, Stoney PN, Collins MO, Papadia S, Choudhary JS, Komiyama NH, Grant SG, Hardingham GE, Wyllie DJ, Kind PC.

Nat Commun. 2012 Jun 12;3:900. doi: 10.1038/ncomms1900.

PMID:
22692543
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis.

Patani R, Lewis PA, Trabzuni D, Puddifoot CA, Wyllie DJ, Walker R, Smith C, Hardingham GE, Weale M, Hardy J, Chandran S, Ryten M.

J Neurochem. 2012 Aug;122(4):738-51. doi: 10.1111/j.1471-4159.2012.07825.x. Epub 2012 Jul 10.

PMID:
22681703
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

PGC-1α negatively regulates extrasynaptic NMDAR activity and excitotoxicity.

Puddifoot C, Martel MA, Soriano FX, Camacho A, Vidal-Puig A, Wyllie DJ, Hardingham GE.

J Neurosci. 2012 May 16;32(20):6995-7000. doi: 10.1523/JNEUROSCI.6407-11.2012.

PMID:
22593067
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

TCN 201 selectively blocks GluN2A-containing NMDARs in a GluN1 co-agonist dependent but non-competitive manner.

Edman S, McKay S, Macdonald LJ, Samadi M, Livesey MR, Hardingham GE, Wyllie DJ.

Neuropharmacology. 2012 Sep;63(3):441-9. doi: 10.1016/j.neuropharm.2012.04.027. Epub 2012 May 1.

PMID:
22579927
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The subtype of GluN2 C-terminal domain determines the response to excitotoxic insults.

Martel MA, Ryan TJ, Bell KF, Fowler JH, McMahon A, Al-Mubarak B, Komiyama NH, Horsburgh K, Kind PC, Grant SG, Wyllie DJ, Hardingham GE.

Neuron. 2012 May 10;74(3):543-56. doi: 10.1016/j.neuron.2012.03.021.

PMID:
22578505
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability.

Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, Wilmut I, Finkbeiner S, Maniatis T, Shaw CE, Chandran S.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5803-8. doi: 10.1073/pnas.1202922109. Epub 2012 Mar 26.

PMID:
22451909
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms.

Gupta K, Patani R, Baxter P, Serio A, Story D, Tsujita T, Hayes JD, Pedersen RA, Hardingham GE, Chandran S.

Cell Death Differ. 2012 May;19(5):779-87. doi: 10.1038/cdd.2011.154. Epub 2011 Nov 18.

PMID:
22095276
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Loading ...
Write to the Help Desk