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Results: 1 to 20 of 33

1.

Sustained expression from DNA vectors.

Wong SP, Argyros O, Harbottle RP.

Adv Genet. 2015;89:113-52. doi: 10.1016/bs.adgen.2014.11.002. Epub 2014 Dec 18.

PMID:
25620010
2.

Treatment of phenylketonuria using minicircle-based naked-DNA gene transfer to murine liver.

Viecelli HM, Harbottle RP, Wong SP, Schlegel A, Chuah MK, VandenDriessche T, Harding CO, Thöny B.

Hepatology. 2014 Sep;60(3):1035-43. doi: 10.1002/hep.27104. Epub 2014 Jul 29.

PMID:
24585515
3.

Minimal-length Synthetic shRNAs Formulated with Lipid Nanoparticles are Potent Inhibitors of Hepatitis C Virus IRES-linked Gene Expression in Mice.

Dallas A, Ilves H, Shorenstein J, Judge A, Spitler R, Contag C, Wong SP, Harbottle RP, Maclachlan I, Johnston BH.

Mol Ther Nucleic Acids. 2013 Sep 17;2:e123. doi: 10.1038/mtna.2013.50.

4.

Genetic modification of dividing cells using episomally maintained S/MAR DNA vectors.

Wong SP, Harbottle RP.

Mol Ther Nucleic Acids. 2013 Aug 13;2:e115. doi: 10.1038/mtna.2013.40.

5.

Birt-Hogg-Dube syndrome is a novel ciliopathy.

Luijten MN, Basten SG, Claessens T, Vernooij M, Scott CL, Janssen R, Easton JA, Kamps MA, Vreeburg M, Broers JL, van Geel M, Menko FH, Harbottle RP, Nookala RK, Tee AR, Land SC, Giles RH, Coull BJ, van Steensel MA.

Hum Mol Genet. 2013 Nov 1;22(21):4383-97. doi: 10.1093/hmg/ddt288. Epub 2013 Jun 19.

6.

Genetic modification of cancer cells using non-viral, episomal S/MAR vectors for in vivo tumour modelling.

Argyros O, Wong SP, Gowers K, Harbottle RP.

PLoS One. 2012;7(10):e47920. doi: 10.1371/journal.pone.0047920. Epub 2012 Oct 26.

7.

Vector systems for prenatal gene therapy: principles of non-viral vector design and production.

Wong SP, Argyros O, Harbottle RP.

Methods Mol Biol. 2012;891:133-67. doi: 10.1007/978-1-61779-873-3_7.

PMID:
22648771
8.

Corneal gene delivery: chitosan oligomer as a carrier of CpG rich, CpG free or S/MAR plasmid DNA.

Klausner EA, Zhang Z, Wong SP, Chapman RL, Volin MV, Harbottle RP.

J Gene Med. 2012 Feb;14(2):100-8. doi: 10.1002/jgm.1634.

PMID:
22106057
9.

Non-viral episomal modification of cells using S/MAR elements.

Argyros O, Wong SP, Harbottle RP.

Expert Opin Biol Ther. 2011 Sep;11(9):1177-91. doi: 10.1517/14712598.2011.582035. Epub 2011 May 9. Review.

PMID:
21548848
10.

Development of S/MAR minicircles for enhanced and persistent transgene expression in the mouse liver.

Argyros O, Wong SP, Fedonidis C, Tolmachov O, Waddington SN, Howe SJ, Niceta M, Coutelle C, Harbottle RP.

J Mol Med (Berl). 2011 May;89(5):515-29. doi: 10.1007/s00109-010-0713-3. Epub 2011 Feb 8.

PMID:
21301798
11.

Systemic gene transfer of polyethylenimine (PEI)-plasmid DNA complexes to neonatal mice.

Wong SP, Argyros O, Howe SJ, Harbottle RP.

J Control Release. 2011 Mar 30;150(3):298-306. doi: 10.1016/j.jconrel.2010.12.010. Epub 2010 Dec 28.

PMID:
21192993
12.

Non-viral S/MAR vectors replicate episomally in vivo when provided with a selective advantage.

Wong SP, Argyros O, Coutelle C, Harbottle RP.

Gene Ther. 2011 Jan;18(1):82-7. doi: 10.1038/gt.2010.116. Epub 2010 Aug 26.

PMID:
20739959
13.

pEPito: a significantly improved non-viral episomal expression vector for mammalian cells.

Haase R, Argyros O, Wong SP, Harbottle RP, Lipps HJ, Ogris M, Magnusson T, Vizoso Pinto MG, Haas J, Baiker A.

BMC Biotechnol. 2010 Mar 15;10:20. doi: 10.1186/1472-6750-10-20.

14.

Strategies for the episomal modification of cells.

Wong SP, Argyros O, Coutelle C, Harbottle RP.

Curr Opin Mol Ther. 2009 Aug;11(4):433-41. Review.

PMID:
19649988
15.

Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector.

Argyros O, Wong SP, Niceta M, Waddington SN, Howe SJ, Coutelle C, Miller AD, Harbottle RP.

Gene Ther. 2008 Dec;15(24):1593-605. doi: 10.1038/gt.2008.113. Epub 2008 Jul 17.

PMID:
18633447
16.

Delivery and long-term expression of a 135 kb LDLR genomic DNA locus in vivo by hydrodynamic tail vein injection.

Hibbitt OC, Harbottle RP, Waddington SN, Bursill CA, Coutelle C, Channon KM, Wade-Martins R.

J Gene Med. 2007 Jun;9(6):488-97.

PMID:
17471590
17.

Nuclear-targeted minicircle to enhance gene transfer with non-viral vectors in vitro and in vivo.

Vaysse L, Gregory LG, Harbottle RP, Perouzel E, Tolmachov O, Coutelle C.

J Gene Med. 2006 Jun;8(6):754-63.

PMID:
16532508
18.

Synthesis and application of integrin targeting lipopeptides in targeted gene delivery.

Waterhouse JE, Harbottle RP, Keller M, Kostarelos K, Coutelle C, Jorgensen MR, Miller AD.

Chembiochem. 2005 Jul;6(7):1212-23.

PMID:
15937988
19.

Nuclear localisation sequence templated nonviral gene delivery vectors: investigation of intracellular trafficking events of LMD and LD vector systems.

Keller M, Harbottle RP, Perouzel E, Colin M, Shah I, Rahim A, Vaysse L, Bergau A, Moritz S, Brahimi-Horn C, Coutelle C, Miller AD.

Chembiochem. 2003 Apr 4;4(4):286-98.

PMID:
12672108
20.

Enhancement of adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in vivo.

Gregory LG, Harbottle RP, Lawrence L, Knapton HJ, Themis M, Coutelle C.

Mol Ther. 2003 Jan;7(1):19-26.

PMID:
12573614
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