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Results: 1 to 20 of 348

1.

Selective, efficient modulation of activated CD4+ αβT cells by the novel humanized antibody GZ-αβTCR targeting human αβTCR.

Blank G, Welker C, Haarer J, Sterk M, Nadalin S, Yañez VA, Joos TO, Menrad A, Snell D, LaCorcia G, Königsrainer A, Handgretinger R, Schilbach K.

Bone Marrow Transplant. 2014 Nov 17. doi: 10.1038/bmt.2014.263. [Epub ahead of print]

PMID:
25402416
[PubMed - as supplied by publisher]
2.

Both mature KIR+ and immature KIR- NK cells control pediatric acute B cell precursor leukemia in NOD.Cg-Prkdcscid IL2rgtmWjl/Sz mice.

Kübler A, Woiterski J, Witte KE, Bühring HJ, Hartwig UF, Ebinger M, Oevermann L, Mezger M, Herr W, Lang P, Handgretinger R, Münz C, André MC.

Blood. 2014 Oct 30. pii: blood-2014-05-572743. [Epub ahead of print]

PMID:
25359989
[PubMed - as supplied by publisher]
3.

Tumour volume reduction after neoadjuvant chemotherapy impacts outcome in localised embryonal rhabdomyosarcoma.

Dantonello TM, Stark M, Timmermann B, Fuchs J, Selle B, Linderkamp C, Handgretinger R, Hagen R, Feuchtgruber S, Kube S, Kosztyla D, Kazanowska B, Ladenstein R, Niggli F, Ljungman G, Bielack SS, Klingebiel T, Koscielniak E; Cooperative Weichteilsarkom Studiengruppe [CWS].

Pediatr Blood Cancer. 2015 Jan;62(1):16-23. doi: 10.1002/pbc.25207. Epub 2014 Sep 27.

PMID:
25263634
[PubMed - in process]
4.

Differential expression of THELPER 1 cytokines upon antigen stimulation predicts ex vivo proliferative potential and cytokine production of virus-specific T cells following re-stimulation.

Feucht J, Leibold J, Halder A, Kayser S, Hartl L, Rammensee HG, Handgretinger R, Feuchtinger T.

Transpl Infect Dis. 2014 Oct;16(5):713-23. doi: 10.1111/tid.12281. Epub 2014 Sep 9.

PMID:
25200928
[PubMed - in process]
5.

Monocyte-induced development of Th17 cells and the release of S100 proteins are involved in the pathogenesis of graft-versus-host disease.

Reinhardt K, Foell D, Vogl T, Mezger M, Wittkowski H, Fend F, Federmann B, Gille C, Feuchtinger T, Lang P, Handgretinger R, Andreas Bethge W, Holzer U.

J Immunol. 2014 Oct 1;193(7):3355-65. doi: 10.4049/jimmunol.1400983. Epub 2014 Sep 3.

PMID:
25187661
[PubMed - indexed for MEDLINE]
6.

KIR B haplotype donors confer a reduced risk for relapse after haploidentical transplantation in children with ALL.

Oevermann L, Michaelis SU, Mezger M, Lang P, Toporski J, Bertaina A, Zecca M, Moretta L, Locatelli F, Handgretinger R.

Blood. 2014 Oct 23;124(17):2744-7. doi: 10.1182/blood-2014-03-565069. Epub 2014 Aug 12.

PMID:
25115891
[PubMed - in process]
Free PMC Article
7.

Human leukocyte antigen DR surface expression on CD14+ monocytes during adverse events after hematopoietic stem cell transplantation.

Döring M, Rohrer KM, Erbacher A, Gieseke F, Schwarze CP, Bader P, Handgretinger R, Hofbeck M, Kerst G.

Ann Hematol. 2014 Aug 13. [Epub ahead of print]

PMID:
25113134
[PubMed - as supplied by publisher]
8.

Haploidentical transplantation: the search for the best donor.

Handgretinger R.

Blood. 2014 Aug 7;124(6):827-8. doi: 10.1182/blood-2014-06-582460. No abstract available.

PMID:
25104858
[PubMed - in process]
Free PMC Article
9.

Will Post-Transplantation Cell Therapies for Pediatric Patients Become Standard of Care?

Lankester AC, Locatelli F, Bader P, Rettinger E, Egeler M, Katewa S, Pulsipher MA, Nierkens S, Schultz K, Handgretinger R, Grupp SA, Boelens JJ, Bollard CM; Westhafen Intercontinental Group.

Biol Blood Marrow Transplant. 2014 Jul 23. pii: S1083-8791(14)00444-3. doi: 10.1016/j.bbmt.2014.07.018. [Epub ahead of print] Review.

PMID:
25064748
[PubMed - as supplied by publisher]
10.

How an accidental discovery paved the way for the treatment of complicated infantile haemangiomas.

Handgretinger R.

Acta Paediatr. 2014 Sep;103(9):896-7. doi: 10.1111/apa.12715. Epub 2014 Jul 7. No abstract available.

PMID:
25040099
[PubMed - in process]
11.

The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse.

Bandapalli OR, Schuessele S, Kunz JB, Rausch T, Stütz AM, Tal N, Geron I, Gershman N, Izraeli S, Eilers J, Vaezipour N, Kirschner-Schwabe R, Hof J, von Stackelberg A, Schrappe M, Stanulla M, Zimmermann M, Koehler R, Avigad S, Handgretinger R, Frismantas V, Bourquin JP, Bornhauser B, Korbel JO, Muckenthaler MU, Kulozik AE.

Haematologica. 2014 Oct;99(10):e188-92. doi: 10.3324/haematol.2014.104992. Epub 2014 Jun 27. No abstract available.

PMID:
24972766
[PubMed - in process]
Free PMC Article
12.

A newborn with grouped facial skin lesions and subsequent seizures.

Döring M, Rohrer KM, Tsiflikas I, Buchenau W, Wilke M, Handgretinger R, Poets CF, Goelz R.

BMC Pediatr. 2014 May 22;14:126. doi: 10.1186/1471-2431-14-126.

PMID:
24884686
[PubMed - in process]
Free PMC Article
13.

HLA-haploidentical stem cell transplantation after removal of αβ+ T and B cells in children with nonmalignant disorders.

Bertaina A, Merli P, Rutella S, Pagliara D, Bernardo ME, Masetti R, Pende D, Falco M, Handgretinger R, Moretta F, Lucarelli B, Brescia LP, Li Pira G, Testi M, Cancrini C, Kabbara N, Carsetti R, Finocchi A, Moretta A, Moretta L, Locatelli F.

Blood. 2014 Jul 31;124(5):822-6. doi: 10.1182/blood-2014-03-563817. Epub 2014 May 28.

PMID:
24869942
[PubMed - indexed for MEDLINE]
14.

Synthesis and biological effects of new hybrid compounds composed of benzylguanidines and the alkylating group of busulfan on neuroblastoma cells.

Hampel T, Bruns M, Bayer M, Handgretinger R, Bruchelt G, Brückner R.

Bioorg Med Chem Lett. 2014 Jun 15;24(12):2728-33. doi: 10.1016/j.bmcl.2014.04.030. Epub 2014 Apr 18.

PMID:
24814532
[PubMed - in process]
15.

KIR haplotype B donors but not KIR-ligand mismatch result in a reduced incidence of relapse after haploidentical transplantation using reduced intensity conditioning and CD3/CD19-depleted grafts.

Michaelis SU, Mezger M, Bornhäuser M, Trenschel R, Stuhler G, Federmann B, Oevermann L, Kanz L, Handgretinger R, Bethge WA.

Ann Hematol. 2014 Sep;93(9):1579-86. doi: 10.1007/s00277-014-2084-2. Epub 2014 Apr 26.

PMID:
24771045
[PubMed - indexed for MEDLINE]
16.

Pediatric posttransplant relapsed/refractory B-precursor acute lymphoblastic leukemia shows durable remission by therapy with the T-cell engaging bispecific antibody blinatumomab.

Schlegel P, Lang P, Zugmaier G, Ebinger M, Kreyenberg H, Witte KE, Feucht J, Pfeiffer M, Teltschik HM, Kyzirakos C, Feuchtinger T, Handgretinger R.

Haematologica. 2014 Jul;99(7):1212-9. doi: 10.3324/haematol.2013.100073. Epub 2014 Apr 11.

PMID:
24727818
[PubMed - in process]
Free PMC Article
17.

Phase I trial of a novel anti-GD2 monoclonal antibody, Hu14.18K322A, designed to decrease toxicity in children with refractory or recurrent neuroblastoma.

Navid F, Sondel PM, Barfield R, Shulkin BL, Kaufman RA, Allay JA, Gan J, Hutson P, Seo S, Kim K, Goldberg J, Hank JA, Billups CA, Wu J, Furman WL, McGregor LM, Otto M, Gillies SD, Handgretinger R, Santana VM.

J Clin Oncol. 2014 May 10;32(14):1445-52. doi: 10.1200/JCO.2013.50.4423. Epub 2014 Apr 7.

PMID:
24711551
[PubMed - indexed for MEDLINE]
18.

In melanoma, Hippo signaling is affected by copy number alterations and YAP1 overexpression impairs patient survival.

Menzel M, Meckbach D, Weide B, Toussaint NC, Schilbach K, Noor S, Eigentler T, Ikenberg K, Busch C, Quintanilla-Martinez L, Kohlhofer U, Göke A, Göke F, Handgretinger R, Ottmann C, Bastian BC, Garbe C, Röcken M, Perner S, Kohlbacher O, Bauer J.

Pigment Cell Melanoma Res. 2014 Jul;27(4):671-3. doi: 10.1111/pcmr.12249. Epub 2014 May 6. No abstract available.

PMID:
24703331
[PubMed - in process]
19.

Combined PET/MR: Where are we now? Summary report of the second international workshop on PET/MR imaging April 8-12, 2013, Tubingen, Germany.

Bailey DL, Barthel H, Beuthin-Baumann B, Beyer T, Bisdas S, Boellaard R, Czernin J, Drzezga A, Ernemann U, Franzius C, Gückel B, Handgretinger R, Hartenbach M, Hellwig D, Nadel H, Nekolla SG, Pfluger T, Pichler BJ, Quick HH, Sabri O, Sattler B, Schäfer J, Schick F, Siegel BA, Schlemmer HP, Schwenzer NF, van den Hoff J, Veit-Haibach P, Wehrl HF.

Mol Imaging Biol. 2014 Jun;16(3):295-310. doi: 10.1007/s11307-014-0725-4.

PMID:
24668195
[PubMed - in process]
20.

Haploidentical stem cell transplantation in DOCK8 deficiency - Successful control of pre-existing severe viremia with a TCRaß/CD19-depleted graft and antiviral treatment.

Ghosh S, Schuster FR, Adams O, Babor F, Borkhardt A, Comoli P, Handgretinger R, Lang P, Laws HJ, Siepermann M, Meisel R.

Clin Immunol. 2014 May-Jun;152(1-2):111-4. doi: 10.1016/j.clim.2014.03.006. Epub 2014 Mar 22. No abstract available.

PMID:
24667686
[PubMed - indexed for MEDLINE]

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