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Ferritin as an early marker of graft rejection after allogeneic hematopoietic stem cell transplantation in pediatric patients.

Döring M, Cabanillas Stanchi KM, Feucht J, Queudeville M, Teltschik HM, Lang P, Feuchtinger T, Handgretinger R, Müller I.

Ann Hematol. 2015 Nov 27. [Epub ahead of print]


Modified mRNA as a new therapeutic option for pediatric respiratory diseases and hemoglobinopathies.

Antony JS, Dewerth A, Haque A, Handgretinger R, Kormann MS.

Mol Cell Pediatr. 2015 Dec;2(1):11. Epub 2015 Nov 20.


Hoechst 33342 Staining Identifies the Progenitor Side Population in NOD.Cg-PrkdcscidIL2rgtmWjl/Sz Mice Harboring Pediatric Leukemias.

Andre MC, Witte KE, Hoerrmann RA, Schmitt A, Handgretinger R, Ebinger M.

In Vivo. 2015 11-12;29(6):661-669.


Posaconazole plasma concentration in pediatric patients receiving antifungal prophylaxis after allogeneic hematopoietic stem cell transplantation.

Heinz WJ, Cabanillas Stanchi KM, Klinker H, Blume O, Feucht J, Hartmann U, Feuchtinger T, Lang P, Handgretinger R, Döring M.

Med Mycol. 2015 Oct 18. pii: myv087. [Epub ahead of print]


Enriched Bone Marrow Derived Disseminated Neuroblastoma Cells Can Be a Reliable Source for Gene Expression Studies-A Validation Study.

Rifatbegovic F, Abbasi MR, Taschner-Mandl S, Kauer M, Weinhäusel A, Handgretinger R, Ambros PF.

PLoS One. 2015 Sep 11;10(9):e0137995. doi: 10.1371/journal.pone.0137995. eCollection 2015.


Cytokine serum levels during post-transplant adverse events in 61 pediatric patients after hematopoietic stem cell transplantation.

Döring M, Cabanillas Stanchi KM, Mezger M, Erbacher A, Feucht J, Pfeiffer M, Lang P, Handgretinger R, Müller I.

BMC Cancer. 2015 Aug 28;15:607. doi: 10.1186/s12885-015-1616-z.


Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation.

Kunz JB, Rausch T, Bandapalli OR, Eilers J, Pechanska P, Schuessele S, Assenov Y, Stütz AM, Kirschner-Schwabe R, Hof J, Eckert C, von Stackelberg A, Schrappe M, Stanulla M, Koehler R, Avigad S, Elitzur S, Handgretinger R, Benes V, Weischenfeldt J, Korbel JO, Muckenthaler MU, Kulozik AE.

Haematologica. 2015 Nov;100(11):1442-50. doi: 10.3324/haematol.2015.129692. Epub 2015 Aug 20.


Preemptive administration of human αβ T cell receptor-targeting monoclonal antibody GZ-αβTCR potently abrogates aggressive graft-versus-host disease in vivo.

Blank G, Welker C, Sipos B, Sonntag K, Müller F, Eckert F, Seitz C, Nadalin S, LaCorcia G, Königsrainer A, Snell D, Handgretinger R, Schilbach K.

Ann Hematol. 2015 Nov;94(11):1907-19. doi: 10.1007/s00277-015-2471-3. Epub 2015 Aug 13.


NKG2D Signaling Leads to NK Cell Mediated Lysis of Childhood AML.

Schlegel P, Ditthard K, Lang P, Mezger M, Michaelis S, Handgretinger R, Pfeiffer M.

J Immunol Res. 2015;2015:473175. doi: 10.1155/2015/473175. Epub 2015 Jul 8.


Nifurtimox reduces N-Myc expression and aerobic glycolysis in neuroblastoma.

Cabanillas Stanchi KM, Bruchelt G, Handgretinger R, Holzer U.

Cancer Biol Ther. 2015 Sep 2;16(9):1353-63. doi: 10.1080/15384047.2015.1070987. Epub 2015 Jul 15.


Rapid generation of NY-ESO-1-specific CD4+ THELPER1 cells for adoptive T-cell therapy.

Kayser S, Boβ C, Feucht J, Witte KE, Scheu A, Bülow HJ, Joachim S, Stevanović S, Schumm M, Rittig SM, Lang P, Röcken M, Handgretinger R, Feuchtinger T.

Oncoimmunology. 2015 May 21;4(5):e1002723. eCollection 2015 May.


Chronic graft-versus-host-disease in CD34(+)-humanized NSG mice is associated with human susceptibility HLA haplotypes for autoimmune disease.

Sonntag K, Eckert F, Welker C, Müller H, Müller F, Zips D, Sipos B, Klein R, Blank G, Feuchtinger T, Schumm M, Handgretinger R, Schilbach K.

J Autoimmun. 2015 Aug;62:55-66. doi: 10.1016/j.jaut.2015.06.006. Epub 2015 Jul 3.


Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation.

Schilbach K, Alkhaled M, Welker C, Eckert F, Blank G, Ziegler H, Sterk M, Müller F, Sonntag K, Wieder T, Braumüller H, Schmitt J, Eyrich M, Schleicher S, Seitz C, Erbacher A, Pichler BJ, Müller H, Tighe R, Lim A, Gillies SD, Strittmatter W, Röcken M, Handgretinger R.

Oncoimmunology. 2015 Mar 19;4(7):e1014760. eCollection 2015 Jul.


Donor choice in haploidentical stem cell transplantation: fetal microchimerism is associated with better outcome in pediatric leukemia patients.

Kruchen A, Stahl T, Gieseke F, Binder TM, Özcan Z, Meisel R, Kreyenberg H, Bader P, Gruhn B, Greil J, Pfeiffer M, Döring M, Handgretinger R, Fehse B, Müller I.

Bone Marrow Transplant. 2015 Oct;50(10):1367-70. doi: 10.1038/bmt.2015.136. Epub 2015 Jun 22. No abstract available.


Favorable NK cell activity after haploidentical hematopoietic stem cell transplantation in stage IV relapsed Ewing's sarcoma patients.

Schlegel P, Feuchtinger T, Nitschke-Gérard C, Seidel UJ, Lang AM, Kyzirakos C, Teltschik HM, Ebinger M, Schumm M, Koscielniak E, Handgretinger R, Lang P.

Bone Marrow Transplant. 2015 Jun;50 Suppl 2:S72-6. doi: 10.1038/bmt.2015.100.


Improved immune recovery after transplantation of TCRαβ/CD19-depleted allografts from haploidentical donors in pediatric patients.

Lang P, Feuchtinger T, Teltschik HM, Schwinger W, Schlegel P, Pfeiffer M, Schumm M, Lang AM, Lang B, Schwarze CP, Ebinger M, Urban C, Handgretinger R.

Bone Marrow Transplant. 2015 Jun;50 Suppl 2:S6-10. doi: 10.1038/bmt.2015.87.


No association between the presence of killer-cell immunoglobulin-like receptor genes and susceptibility to childhood ALL.

Oevermann L, Firnkorn M, Michaelis S, Müller S, Schaeffeler E, Schrappe M, Cario G, Stanulla M, Schwab M, Handgretinger R, Mezger M.

Blood. 2015 May 21;125(21):3355-7. doi: 10.1182/blood-2015-02-628339. No abstract available.


Consensus of German transplant centers on hematopoietic stem cell transplantation in Fanconi anemia.

Chao MM, Ebell W, Bader P, Beier R, Burkhardt B, Feuchtinger T, Handgretinger R, Hanenberg H, Koehl U, Kratz C, Kremens B, Lang P, Meisel R, Mueller I, Roessig C, Sauer M, Schlegel PG, Schulz A, Strahm B, Thol F, Sykora KW.

Klin Padiatr. 2015 May;227(3):157-65. doi: 10.1055/s-0035-1548841. Epub 2015 May 18.


In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency.

Mahiny AJ, Dewerth A, Mays LE, Alkhaled M, Mothes B, Malaeksefat E, Loretz B, Rottenberger J, Brosch DM, Reautschnig P, Surapolchai P, Zeyer F, Schams A, Carevic M, Bakele M, Griese M, Schwab M, Nürnberg B, Beer-Hammer S, Handgretinger R, Hartl D, Lehr CM, Kormann MS.

Nat Biotechnol. 2015 Jun;33(6):584-6. doi: 10.1038/nbt.3241. Epub 2015 May 18. No abstract available.


Chorein addiction in VPS13A overexpressing rhabdomyosarcoma cells.

Honisch S, Yu W, Liu G, Alesutan I, Towhid ST, Tsapara A, Schleicher S, Handgretinger R, Stournaras C, Lang F.

Oncotarget. 2015 Apr 30;6(12):10309-19.

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