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Items: 1 to 20 of 21


MicroRNA-122 Regulates Polyploidization in the Murine Liver.

Hsu SH, Delgado ER, Otero PA, Teng KY, Kutay H, Meehan KM, Moroney JB, Monga JK, Hand NJ, Friedman JR, Ghoshal K, Duncan AW.

Hepatology. 2016 Mar 26. doi: 10.1002/hep.28573. [Epub ahead of print]


Therapeutic Targets of Triglyceride Metabolism as Informed by Human Genetics.

Bauer RC, Khetarpal SA, Hand NJ, Rader DJ.

Trends Mol Med. 2016 Apr;22(4):328-40. doi: 10.1016/j.molmed.2016.02.005. Epub 2016 Mar 14. Review.


From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease.

Nurnberg ST, Zhang H, Hand NJ, Bauer RC, Saleheen D, Reilly MP, Rader DJ.

Circ Res. 2016 Feb 19;118(4):586-606. doi: 10.1161/CIRCRESAHA.115.306464.


Apoptosis-induced activation of HIV-1 in latently infected cell lines.

Khan SZ, Hand N, Zeichner SL.

Retrovirology. 2015 May 16;12:42. doi: 10.1186/s12977-015-0169-1.


Pediatric eosinophilic esophagitis is associated with changes in esophageal microRNAs.

Zahm AM, Menard-Katcher C, Benitez AJ, Tsoucas DM, Le Guen CL, Hand NJ, Friedman JR.

Am J Physiol Gastrointest Liver Physiol. 2014 Oct 15;307(8):G803-12. doi: 10.1152/ajpgi.00121.2014. Epub 2014 Aug 21.


Rectal microRNAs are perturbed in pediatric inflammatory bowel disease of the colon.

Zahm AM, Hand NJ, Tsoucas DM, Le Guen CL, Baldassano RN, Friedman JR.

J Crohns Colitis. 2014 Sep;8(9):1108-17. doi: 10.1016/j.crohns.2014.02.012. Epub 2014 Mar 7.


Novel targets of miR-30, a microRNA required for biliary development.

Le Guen CL, Friedman JR, Hand NJ.

F1000Res. 2013 Sep 24;2:197. doi: 10.12688/f1000research.2-197.v1. eCollection 2013.


Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets.

Kameswaran V, Bramswig NC, McKenna LB, Penn M, Schug J, Hand NJ, Chen Y, Choi I, Vourekas A, Won KJ, Liu C, Vivek K, Naji A, Friedman JR, Kaestner KH.

Cell Metab. 2014 Jan 7;19(1):135-45. doi: 10.1016/j.cmet.2013.11.016. Epub 2013 Dec 26.


Extrahepatic cholangiocyte cilia are abnormal in biliary atresia.

Karjoo S, Hand NJ, Loarca L, Russo PA, Friedman JR, Wells RG.

J Pediatr Gastroenterol Nutr. 2013 Jul;57(1):96-101. doi: 10.1097/MPG.0b013e318296e525.


Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver.

Schug J, McKenna LB, Walton G, Hand N, Mukherjee S, Essuman K, Shi Z, Gao Y, Markley K, Nakagawa M, Kameswaran V, Vourekas A, Friedman JR, Kaestner KH, Greenbaum LE.

BMC Genomics. 2013 Apr 18;14:264. doi: 10.1186/1471-2164-14-264.


Circulating microRNA is a biomarker of biliary atresia.

Zahm AM, Hand NJ, Boateng LA, Friedman JR.

J Pediatr Gastroenterol Nutr. 2012 Oct;55(4):366-9.


CpG methylation as a tool to characterize cell-free Kaposi sarcoma herpesvirus DNA.

Shamay M, Hand N, Lemas MV, Koon HB, Krown SE, Wrangle J, Desai P, Ramos JC, Ambinder RF.

J Infect Dis. 2012 Apr 1;205(7):1095-9. doi: 10.1093/infdis/jis032. Epub 2012 Feb 22.


MicroRNA profiling identifies miR-29 as a regulator of disease-associated pathways in experimental biliary atresia.

Hand NJ, Horner AM, Master ZR, Boateng LA, LeGuen C, Uvaydova M, Friedman JR.

J Pediatr Gastroenterol Nutr. 2012 Feb;54(2):186-92. doi: 10.1097/MPG.0b013e318244148b.


Circulating microRNA is a biomarker of pediatric Crohn disease.

Zahm AM, Thayu M, Hand NJ, Horner A, Leonard MB, Friedman JR.

J Pediatr Gastroenterol Nutr. 2011 Jul;53(1):26-33. doi: 10.1097/MPG.0b013e31822200cc.


The microRNA-30 family is required for vertebrate hepatobiliary development.

Hand NJ, Master ZR, Eauclaire SF, Weinblatt DE, Matthews RP, Friedman JR.

Gastroenterology. 2009 Mar;136(3):1081-90. doi: 10.1053/j.gastro.2008.12.006. Epub 2008 Dec 9.


Hepatic function is preserved in the absence of mature microRNAs.

Hand NJ, Master ZR, Le Lay J, Friedman JR.

Hepatology. 2009 Feb;49(2):618-26. doi: 10.1002/hep.22656.


prlF and yhaV encode a new toxin-antitoxin system in Escherichia coli.

Schmidt O, Schuenemann VJ, Hand NJ, Silhavy TJ, Martin J, Lupas AN, Djuranovic S.

J Mol Biol. 2007 Sep 28;372(4):894-905. Epub 2007 Jul 21.


Archaeal and bacterial SecD and SecF homologs exhibit striking structural and functional conservation.

Hand NJ, Klein R, Laskewitz A, Pohlschröder M.

J Bacteriol. 2006 Feb;188(4):1251-9.


Diversity and evolution of protein translocation.

Pohlschröder M, Hartmann E, Hand NJ, Dilks K, Haddad A.

Annu Rev Microbiol. 2005;59:91-111. Review.


Translocation of proteins across archaeal cytoplasmic membranes.

Pohlschröder M, Dilks K, Hand NJ, Wesley Rose R.

FEMS Microbiol Rev. 2004 Feb;28(1):3-24. Review.

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