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Results: 17

1.

Agent-based modeling of autophagy reveals emergent regulatory behavior of spatio-temporal autophagy dynamics.

Börlin CS, Lang V, Hamacher-Brady A, Brady NR.

Cell Commun Signal. 2014 Sep 10;12(1):56. [Epub ahead of print]

PMID:
25214434
[PubMed - as supplied by publisher]
Free PMC Article
2.

Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase.

Hamacher-Brady A, Choe SC, Krijnse-Locker J, Brady NR.

Cell Death Differ. 2014 Dec;21(12):1862-76. doi: 10.1038/cdd.2014.101. Epub 2014 Aug 1.

PMID:
25080938
[PubMed - in process]
3.

Histone deacetylase 10 promotes autophagy-mediated cell survival.

Oehme I, Linke JP, Böck BC, Milde T, Lodrini M, Hartenstein B, Wiegand I, Eckert C, Roth W, Kool M, Kaden S, Gröne HJ, Schulte JH, Lindner S, Hamacher-Brady A, Brady NR, Deubzer HE, Witt O.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):E2592-601. doi: 10.1073/pnas.1300113110. Epub 2013 Jun 25.

PMID:
23801752
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Modulation of serines 17 and 24 in the LC3-interacting region of Bnip3 determines pro-survival mitophagy versus apoptosis.

Zhu Y, Massen S, Terenzio M, Lang V, Chen-Lindner S, Eils R, Novak I, Dikic I, Hamacher-Brady A, Brady NR.

J Biol Chem. 2013 Jan 11;288(2):1099-113. doi: 10.1074/jbc.M112.399345. Epub 2012 Dec 3.

PMID:
23209295
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Antagonistic regulation of apoptosis and differentiation by the Cut transcription factor represents a tumor-suppressing mechanism in Drosophila.

Zhai Z, Ha N, Papagiannouli F, Hamacher-Brady A, Brady N, Sorge S, Bezdan D, Lohmann I.

PLoS Genet. 2012;8(3):e1002582. doi: 10.1371/journal.pgen.1002582. Epub 2012 Mar 15.

PMID:
22438831
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Multi-parametric analysis and modeling of relationships between mitochondrial morphology and apoptosis.

Reis Y, Bernardo-Faura M, Richter D, Wolf T, Brors B, Hamacher-Brady A, Eils R, Brady NR.

PLoS One. 2012;7(1):e28694. doi: 10.1371/journal.pone.0028694. Epub 2012 Jan 17.

PMID:
22272225
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Autophagy regulation and integration with cell signaling.

Hamacher-Brady A.

Antioxid Redox Signal. 2012 Sep 1;17(5):756-65. doi: 10.1089/ars.2011.4410. Epub 2012 Jan 25. Review.

PMID:
22149388
[PubMed - indexed for MEDLINE]
8.

Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy.

Hundeshagen P, Hamacher-Brady A, Eils R, Brady NR.

BMC Biol. 2011 Jun 2;9:38. doi: 10.1186/1741-7007-9-38.

PMID:
21635740
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production.

Hamacher-Brady A, Stein HA, Turschner S, Toegel I, Mora R, Jennewein N, Efferth T, Eils R, Brady NR.

J Biol Chem. 2011 Feb 25;286(8):6587-601. doi: 10.1074/jbc.M110.210047. Epub 2010 Dec 13.

PMID:
21149439
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Autophagy and protein kinase C are required for cardioprotection by sulfaphenazole.

Huang C, Liu W, Perry CN, Yitzhaki S, Lee Y, Yuan H, Tsukada YT, Hamacher-Brady A, Mentzer RM Jr, Gottlieb RA.

Am J Physiol Heart Circ Physiol. 2010 Feb;298(2):H570-9. doi: 10.1152/ajpheart.00716.2009. Epub 2009 Dec 11.

PMID:
20008275
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco/endoplasmic reticulum calcium stores.

Brady NR, Hamacher-Brady A, Yuan H, Gottlieb RA.

FEBS J. 2007 Jun;274(12):3184-97.

PMID:
17540004
[PubMed - indexed for MEDLINE]
12.

The interplay between pro-death and pro-survival signaling pathways in myocardial ischemia/reperfusion injury: apoptosis meets autophagy.

Hamacher-Brady A, Brady NR, Gottlieb RA.

Cardiovasc Drugs Ther. 2006 Dec;20(6):445-62. Review.

PMID:
17149555
[PubMed - indexed for MEDLINE]
13.

A wave of reactive oxygen species (ROS)-induced ROS release in a sea of excitable mitochondria.

Brady NR, Hamacher-Brady A, Westerhoff HV, Gottlieb RA.

Antioxid Redox Signal. 2006 Sep-Oct;8(9-10):1651-65. Review.

PMID:
16987019
[PubMed - indexed for MEDLINE]
14.

Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes.

Hamacher-Brady A, Brady NR, Gottlieb RA.

J Biol Chem. 2006 Oct 6;281(40):29776-87. Epub 2006 Aug 1.

PMID:
16882669
[PubMed - indexed for MEDLINE]
Free Article
15.

Autophagy as a protective response to Bnip3-mediated apoptotic signaling in the heart.

Hamacher-Brady A, Brady NR, Gottlieb RA, Gustafsson AB.

Autophagy. 2006 Oct-Dec;2(4):307-9. Epub 2006 Oct 25.

PMID:
16874059
[PubMed - indexed for MEDLINE]
Free Article
16.

Proapoptotic BCL-2 family members and mitochondrial dysfunction during ischemia/reperfusion injury, a study employing cardiac HL-1 cells and GFP biosensors.

Brady NR, Hamacher-Brady A, Gottlieb RA.

Biochim Biophys Acta. 2006 May-Jun;1757(5-6):667-78. Epub 2006 Apr 20.

PMID:
16730326
[PubMed - indexed for MEDLINE]
Free Article
17.

Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy.

Hamacher-Brady A, Brady NR, Logue SE, Sayen MR, Jinno M, Kirshenbaum LA, Gottlieb RA, Gustafsson AB.

Cell Death Differ. 2007 Jan;14(1):146-57. Epub 2006 Apr 28.

PMID:
16645637
[PubMed - indexed for MEDLINE]
Free Article

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