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Items: 1 to 20 of 65

1.

Quantitative projection of human brain penetration of the H<sub>3</sub> antagonist PF-03654746 by integrating rat-derived brain partitioning and PET receptor occupancy.

Sawant-Basak A, Chen L, Shaffer CL, Palumbo D, Schmidt A, Tseng E, Spracklin DK, Gallezot JD, Labaree D, Nabulsi N, Huang Y, Carson RE, McCarthy T.

Xenobiotica. 2016 Jun 29:1-8. [Epub ahead of print]

PMID:
27353353
2.

Determination of receptor occupancy in the presence of mass dose: [11C]GSK189254 PET imaging of histamine H3 receptor occupancy by PF-03654746.

Gallezot JD, Planeta B, Nabulsi N, Palumbo D, Li X, Liu J, Rowinski C, Chidsey K, Labaree D, Ropchan J, Lin SF, Sawant-Basak A, McCarthy TJ, Schmidt AW, Huang Y, Carson RE.

J Cereb Blood Flow Metab. 2016 May 20. pii: 0271678X16650697. [Epub ahead of print]

PMID:
27207170
3.

[(11)C]TASP457, a novel PET ligand for histamine H3 receptors in human brain.

Kimura Y, Seki C, Ikoma Y, Ichise M, Kawamura K, Takahata K, Moriguchi S, Nagashima T, Ishii T, Kitamura S, Niwa F, Endo H, Yamada M, Higuchi M, Zhang MR, Suhara T.

Eur J Nucl Med Mol Imaging. 2016 Aug;43(9):1653-63. doi: 10.1007/s00259-016-3332-6. Epub 2016 Feb 23.

PMID:
26902370
4.

Development of TASP0410457 (TASP457), a novel dihydroquinolinone derivative as a PET radioligand for central histamine H3 receptors.

Koga K, Maeda J, Tokunaga M, Hanyu M, Kawamura K, Ohmichi M, Nakamura T, Nagai Y, Seki C, Kimura Y, Minamimoto T, Zhang MR, Fukumura T, Suhara T, Higuchi M.

EJNMMI Res. 2016 Dec;6(1):11. doi: 10.1186/s13550-016-0170-2. Epub 2016 Feb 9.

5.

Discovery and Preclinical Validation of [(11)C]AZ13153556, a Novel Probe for the Histamine Type 3 Receptor.

Schou M, Varnäs K, Jureus A, Ahlgren C, Malmquist J, Häggkvist J, Tari L, Wesolowski SS, Throner SR, Brown DG, Nilsson M, Johnström P, Finnema SJ, Nakao R, Amini N, Takano A, Farde L.

ACS Chem Neurosci. 2016 Feb 17;7(2):177-84. doi: 10.1021/acschemneuro.5b00268. Epub 2015 Nov 30.

PMID:
26529287
6.

Biopsy in a series of 130 pediatric diffuse intrinsic Pontine gliomas.

Puget S, Beccaria K, Blauwblomme T, Roujeau T, James S, Grill J, Zerah M, Varlet P, Sainte-Rose C.

Childs Nerv Syst. 2015 Oct;31(10):1773-80. doi: 10.1007/s00381-015-2832-1. Epub 2015 Sep 9.

PMID:
26351229
7.

Braf mutation in interdigitating dendritic cell sarcoma: a case report and review of the literature.

Di Liso E, Pennelli N, Lodovichetti G, Ghiotto C, Dei Tos AP, Conte P, Bonanno L.

Cancer Biol Ther. 2015;16(8):1128-35. doi: 10.1080/15384047.2015.1057359. Review.

8.

AMG 595, an Anti-EGFRvIII Antibody-Drug Conjugate, Induces Potent Antitumor Activity against EGFRvIII-Expressing Glioblastoma.

Hamblett KJ, Kozlosky CJ, Siu S, Chang WS, Liu H, Foltz IN, Trueblood ES, Meininger D, Arora T, Twomey B, Vonderfecht SL, Chen Q, Hill JS, Fanslow WC.

Mol Cancer Ther. 2015 Jul;14(7):1614-24. doi: 10.1158/1535-7163.MCT-14-1078. Epub 2015 Apr 30.

9.

The receptor for advanced glycation end products (RAGE) enhances autophagy and neutrophil extracellular traps in pancreatic cancer.

Boone BA, Orlichenko L, Schapiro NE, Loughran P, Gianfrate GC, Ellis JT, Singhi AD, Kang R, Tang D, Lotze MT, Zeh HJ.

Cancer Gene Ther. 2015 Jun;22(6):326-34. doi: 10.1038/cgt.2015.21. Epub 2015 Apr 24.

10.

Damage-associated molecular pattern-activated neutrophil extracellular trap exacerbates sterile inflammatory liver injury.

Huang H, Tohme S, Al-Khafaji AB, Tai S, Loughran P, Chen L, Wang S, Kim J, Billiar T, Wang Y, Tsung A.

Hepatology. 2015 Aug;62(2):600-14. doi: 10.1002/hep.27841. Epub 2015 May 29.

11.

Induction of post-menstrual regeneration by ovarian steroid withdrawal in the functionalis of xenografted human endometrium.

Coudyzer P, Lemoine P, Po C, Jordan BF, Van Der Smissen P, Courtoy PJ, Henriet P, Marbaix E.

Hum Reprod. 2015 May;30(5):1156-68. doi: 10.1093/humrep/dev043. Epub 2015 Mar 6.

12.

Activation of histamine H3 receptor decreased cytoplasmic Ca(2+) imaging during electrical stimulation in the skeletal myotubes.

Chen Y, Paavola J, Stegajev V, Stark H, Chazot PL, Wen JG, Konttinen YT.

Eur J Pharmacol. 2015 May 5;754:173-8. doi: 10.1016/j.ejphar.2015.02.035. Epub 2015 Mar 3.

PMID:
25746421
13.

New Face for Chromatin-Related Mesenchymal Modulator: n-CHD9 Localizes to Nucleoli and Interacts With Ribosomal Genes.

Salomon-Kent R, Marom R, John S, Dundr M, Schiltz LR, Gutierrez J, Workman J, Benayahu D, Hager GL.

J Cell Physiol. 2015 Sep;230(9):2270-80. doi: 10.1002/jcp.24960.

PMID:
25689118
14.

Nuclear trafficking, histone cleavage and induction of apoptosis by the meningococcal App and MspA autotransporters.

Khairalla AS, Omer SA, Mahdavi J, Aslam A, Dufailu OA, Self T, Jonsson AB, Geörg M, Sjölinder H, Royer PJ, Martinez-Pomares L, Ghaemmaghami AM, Wooldridge KG, Oldfield NJ, Ala'Aldeen DA.

Cell Microbiol. 2015 Jul;17(7):1008-20. doi: 10.1111/cmi.12417. Epub 2015 Feb 8.

PMID:
25600171
15.

Conformational features and binding affinities to Cripto, ALK7 and ALK4 of Nodal synthetic fragments.

Calvanese L, Sandomenico A, Caporale A, Focà A, Focà G, D'Auria G, Falcigno L, Ruvo M.

J Pept Sci. 2015 Apr;21(4):283-93. doi: 10.1002/psc.2733. Epub 2015 Jan 15.

PMID:
25588905
16.

Assessment of [125I]WYE-230949 as a novel histamine H3 receptor radiopharmaceutical.

Lewis DY, Champion S, Wyper D, Dewar D, Pimlott S.

PLoS One. 2014 Dec 26;9(12):e115876. doi: 10.1371/journal.pone.0115876. eCollection 2014.

17.

Regulation of RNA polymerase II activation by histone acetylation in single living cells.

Stasevich TJ, Hayashi-Takanaka Y, Sato Y, Maehara K, Ohkawa Y, Sakata-Sogawa K, Tokunaga M, Nagase T, Nozaki N, McNally JG, Kimura H.

Nature. 2014 Dec 11;516(7530):272-5. doi: 10.1038/nature13714. Epub 2014 Sep 21.

PMID:
25252976
18.

EGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage.

Kuroda S, Tam J, Roth JA, Sokolov K, Ramesh R.

Int J Nanomedicine. 2014 Aug 8;9:3825-39. doi: 10.2147/IJN.S65990. eCollection 2014.

19.

Unexpectedly high affinity of a novel histamine H(3) receptor antagonist, GSK239512, in vivo in human brain, determined using PET.

Ashworth S, Berges A, Rabiner EA, Wilson AA, Comley RA, Lai RY, Boardley R, Searle G, Gunn RN, Laruelle M, Cunningham VJ.

Br J Pharmacol. 2014 Mar;171(5):1241-9. doi: 10.1111/bph.12505.

20.

Vascular endothelial growth factor signaling in injured nerves underlies peripheral sensitization in neuropathic pain.

Kiguchi N, Kobayashi Y, Kadowaki Y, Fukazawa Y, Saika F, Kishioka S.

J Neurochem. 2014 Apr;129(1):169-78. doi: 10.1111/jnc.12614. Epub 2013 Dec 4.

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