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immunoClust-An automated analysis pipeline for the identification of immunophenotypic signatures in high-dimensional cytometric datasets.

Sörensen T, Baumgart S, Durek P, Grützkau A, Häupl T.

Cytometry A. 2015 Apr 7. doi: 10.1002/cyto.a.22626. [Epub ahead of print]


miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.

Haftmann C, Stittrich AB, Zimmermann J, Fang Z, Hradilkova K, Bardua M, Westendorf K, Heinz GA, Riedel R, Siede J, Lehmann K, Weinberger EE, Zimmel D, Lauer U, Häupl T, Sieper J, Backhaus M, Neumann C, Hoffmann U, Porstner M, Chen W, Grün JR, Baumgrass R, Matz M, Löhning M, Scheffold A, Wittmann J, Chang HD, Rajewsky N, Jäck HM, Radbruch A, Mashreghi MF.

Eur J Immunol. 2015 Apr;45(4):1192-205. doi: 10.1002/eji.201444633. Epub 2015 Jan 22.


Intermediates caught in the act: tracing insulin amyloid fibril formation in time by combined optical spectroscopy, light scattering, mass spectrometry and microscopy.

Gladytz A, Lugovoy E, Charvat A, Häupl T, Siefermann KR, Abel B.

Phys Chem Chem Phys. 2015 Jan 14;17(2):918-27. doi: 10.1039/c4cp03072a. Epub 2014 Nov 18.


Chemical modification of a tetrapyrrole-type photosensitizer: tuning application and photochemical action beyond the singlet oxygen channel.

Riyad YM, Naumov S, Schastak S, Griebel J, Kahnt A, Häupl T, Neuhaus J, Abel B, Hermann R.

J Phys Chem B. 2014 Oct 9;118(40):11646-58. doi: 10.1021/jp507270k. Epub 2014 Sep 26.


Angiotensin converting enzyme intron 16 insertion/deletion genotype is associated with plasma C-reactive protein concentration in uteroplacental dysfunction.

Häupl T, Zimmermann M, Kalus U, Yürek S, Koscielny J, Hoppe B.

J Renin Angiotensin Aldosterone Syst. 2014 Aug 25. pii: 1470320314539181. [Epub ahead of print]


Upregulation of immunoproteasome subunits in myositis indicates active inflammation with involvement of antigen presenting cells, CD8 T-cells and IFNΓ.

Ghannam K, Martinez-Gamboa L, Spengler L, Krause S, Smiljanovic B, Bonin M, Bhattarai S, Grützkau A, Burmester GR, Häupl T, Feist E.

PLoS One. 2014 Aug 6;9(8):e104048. doi: 10.1371/journal.pone.0104048. eCollection 2014.


Novel application of multi-stimuli network inference to synovial fibroblasts of rheumatoid arthritis patients.

Kupfer P, Huber R, Weber M, Vlaic S, Häupl T, Koczan D, Guthke R, Kinne RW.

BMC Med Genomics. 2014 Jul 3;7:40. doi: 10.1186/1755-8794-7-40.


Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation.

Woetzel D, Huber R, Kupfer P, Pohlers D, Pfaff M, Driesch D, Häupl T, Koczan D, Stiehl P, Guthke R, Kinne RW.

Arthritis Res Ther. 2014 Apr 1;16(2):R84. doi: 10.1186/ar4526.


The influence of the ΔK280 mutation and N- or C-terminal extensions on the structure, dynamics, and fibril morphology of the tau R2 repeat.

Raz Y, Adler J, Vogel A, Scheidt HA, Häupl T, Abel B, Huster D, Miller Y.

Phys Chem Chem Phys. 2014 May 7;16(17):7710-7. doi: 10.1039/c3cp54890b.


Cell-specific type I IFN signatures in autoimmunity and viral infection: what makes the difference?

Kyogoku C, Smiljanovic B, Grün JR, Biesen R, Schulte-Wrede U, Häupl T, Hiepe F, Alexander T, Radbruch A, Grützkau A.

PLoS One. 2013 Dec 31;8(12):e83776. doi: 10.1371/journal.pone.0083776. eCollection 2013.


Reverse differentiation as a gene filtering tool in genome expression profiling of adipogenesis for fat marker gene selection and their analysis.

Ullah M, Stich S, Häupl T, Eucker J, Sittinger M, Ringe J.

PLoS One. 2013 Jul 26;8(7):e69754. doi: 10.1371/journal.pone.0069754. Print 2013.


[New aspects on the pathogenesis of myositis].

Stuhlmüller B, Feist E, Häupl T, Burmester GR, Pipitone N.

Z Rheumatol. 2013 Apr;72(3):209-19. doi: 10.1007/s00393-012-1078-5. German.


The physiologic increase in expression of some type I IFN-inducible genes during pregnancy is not associated with improved disease activity in pregnant patients with rheumatoid arthritis.

Weix J, Häupl T, Raio L, Villiger PM, Förger F.

Transl Res. 2013 Jun;161(6):505-12. doi: 10.1016/j.trsl.2013.02.007. Epub 2013 Mar 16.


[Biomarkers and personalized medicine].

Scherer HU, Burmester GR, Häupl T.

Z Rheumatol. 2013 Feb;72(1):20-6. doi: 10.1007/s00393-011-0884-5. German.


Biocompatible silicon surfaces through orthogonal click chemistries and a high affinity silicon oxide binding peptide.

Hassert R, Pagel M, Ming Z, Häupl T, Abel B, Braun K, Wiessler M, Beck-Sickinger AG.

Bioconjug Chem. 2012 Oct 17;23(10):2129-37. doi: 10.1021/bc3003875. Epub 2012 Sep 27.


The multifaceted balance of TNF-α and type I/II interferon responses in SLE and RA: how monocytes manage the impact of cytokines.

Smiljanovic B, Grün JR, Biesen R, Schulte-Wrede U, Baumgrass R, Stuhlmüller B, Maslinski W, Hiepe F, Burmester GR, Radbruch A, Häupl T, Grützkau A.

J Mol Med (Berl). 2012 Nov;90(11):1295-309. doi: 10.1007/s00109-012-0907-y. Epub 2012 May 19.


[Biomarkers in rheumatology. Biomarkers and imaging for the diagnosis and stratification of rheumatoid arthritis and spondylarthritis in the ArthroMark network funded by the Federal Ministry of Education and Research].

Häupl T, Appel H, Backhaus M, Burkhardt H, Grünke M, Grützkau A, Hoppe B, Listing J, Ostendorf B, Rudwaleit M, Sieper J, Skapenko A, Skriner K, Sörensen T, Stuhlmüller B, Zink A, Schulze-Koops H, Burmester GR.

Z Rheumatol. 2012 Jun;71(4):314-8. doi: 10.1007/s00393-011-0781-y. German.


Chondrogenic differentiation of human subchondral progenitor cells is affected by synovial fluid from donors with osteoarthritis or rheumatoid arthritis.

Krüger JP, Endres M, Neumann K, Stuhlmüller B, Morawietz L, Häupl T, Kaps C.

J Orthop Surg Res. 2012 Mar 13;7:10. doi: 10.1186/1749-799X-7-10.


Downregulation of ErbB3 by Wnt3a contributes to wnt-induced osteoblast differentiation in mesenchymal cells.

Jullien N, Maudinet A, Leloutre B, Ringe J, Häupl T, Marie PJ.

J Cell Biochem. 2012 Jun;113(6):2047-56. doi: 10.1002/jcb.24076.


Fibrinogen and factor XIII A-subunit genotypes interactively influence C-reactive protein levels during inflammation.

Hoppe B, Häupl T, Skapenko A, Ziemer S, Tauber R, Salama A, Schulze-Koops H, Burmester GR, Dörner T.

Ann Rheum Dis. 2012 Jul;71(7):1163-9. doi: 10.1136/annrheumdis-2011-200738. Epub 2012 Jan 20.

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