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Items: 1 to 20 of 33

1.

Targeting the cAMP and Transforming Growth Factor-β Pathway Increases Proliferation to Promote Re-Epithelialization of Human Stem Cell-Derived Retinal Pigment Epithelium.

Choudhary P, Gutteridge A, Impey E, Storer RI, Owen RM, Whiting PJ, Bictash M, Benn CL.

Stem Cells Transl Med. 2016 Apr 25. pii: sctm.2015-0247. [Epub ahead of print]

PMID:
27112176
2.

Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia.

Cao L, McDonnell A, Nitzsche A, Alexandrou A, Saintot PP, Loucif AJ, Brown AR, Young G, Mis M, Randall A, Waxman SG, Stanley P, Kirby S, Tarabar S, Gutteridge A, Butt R, McKernan RM, Whiting P, Ali Z, Bilsland J, Stevens EB.

Sci Transl Med. 2016 Apr 20;8(335):335ra56. doi: 10.1126/scitranslmed.aad7653.

PMID:
27099175
3.

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release.

Alexandrou AJ, Brown AR, Chapman ML, Estacion M, Turner J, Mis MA, Wilbrey A, Payne EC, Gutteridge A, Cox PJ, Doyle R, Printzenhoff D, Lin Z, Marron BE, West C, Swain NA, Storer RI, Stupple PA, Castle NA, Hounshell JA, Rivara M, Randall A, Dib-Hajj SD, Krafte D, Waxman SG, Patel MK, Butt RP, Stevens EB.

PLoS One. 2016 Apr 6;11(4):e0152405. doi: 10.1371/journal.pone.0152405. eCollection 2016.

4.

GNAS mutations are not detected in parosteal and low-grade central osteosarcomas.

Salinas-Souza C, De Andrea C, Bihl M, Kovac M, Pillay N, Forshew T, Gutteridge A, Ye H, Amary MF, Tirabosco R, Toledo SR, Baumhoer D, Flanagan AM.

Mod Pathol. 2015 Oct;28(10):1336-42. doi: 10.1038/modpathol.2015.91. Epub 2015 Aug 7.

PMID:
26248895
5.

Age and growth of the tiger shark Galeocerdo cuvier off the east coast of Australia.

Holmes BJ, Peddemors VM, Gutteridge AN, Geraghty PT, Chan RW, Tibbetts IR, Bennett MB.

J Fish Biol. 2015 Aug;87(2):422-48. doi: 10.1111/jfb.12732.

PMID:
26248806
6.

Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation.

Tassoni A, Gutteridge A, Barber AC, Osborne A, Martin KR.

Stem Cells. 2015 Oct;33(10):3006-16. doi: 10.1002/stem.2095. Epub 2015 Jul 29.

7.

A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells.

Choudhary P, Dodsworth BT, Sidders B, Gutteridge A, Michaelides C, Duckworth JK, Whiting PJ, Benn CL.

PLoS One. 2015 Jun 29;10(6):e0130379. doi: 10.1371/journal.pone.0130379. eCollection 2015.

8.

Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macro-evolution of a double-minute chromosome.

Favero F, McGranahan N, Salm M, Birkbak NJ, Sanborn JZ, Benz SC, Becq J, Peden JF, Kingsbury Z, Grocok RJ, Humphray S, Bentley D, Spencer-Dene B, Gutteridge A, Brada M, Roger S, Dietrich PY, Forshew T, Gerlinger M, Rowan A, Stamp G, Eklund AC, Szallasi Z, Swanton C.

Ann Oncol. 2015 May;26(5):880-7. doi: 10.1093/annonc/mdv127. Epub 2015 Mar 2.

9.

Highly reproducible absolute quantification of Mycobacterium tuberculosis complex by digital PCR.

Devonshire AS, Honeyborne I, Gutteridge A, Whale AS, Nixon G, Wilson P, Jones G, McHugh TD, Foy CA, Huggett JF.

Anal Chem. 2015 Apr 7;87(7):3706-13. doi: 10.1021/ac5041617. Epub 2015 Mar 10.

PMID:
25646934
10.

Optimizing the leveraging of real-world data to improve the development and use of medicines.

Berger ML, Lipset C, Gutteridge A, Axelsen K, Subedi P, Madigan D.

Value Health. 2015 Jan;18(1):127-30. doi: 10.1016/j.jval.2014.10.009. Epub 2014 Nov 27. Review.

11.

Towards standardisation of cell-free DNA measurement in plasma: controls for extraction efficiency, fragment size bias and quantification.

Devonshire AS, Whale AS, Gutteridge A, Jones G, Cowen S, Foy CA, Huggett JF.

Anal Bioanal Chem. 2014 Oct;406(26):6499-512. doi: 10.1007/s00216-014-7835-3. Epub 2014 May 24.

12.

Characterizing human stem cell-derived sensory neurons at the single-cell level reveals their ion channel expression and utility in pain research.

Young GT, Gutteridge A, Fox HD, Wilbrey AL, Cao L, Cho LT, Brown AR, Benn CL, Kammonen LR, Friedman JH, Bictash M, Whiting P, Bilsland JG, Stevens EB.

Mol Ther. 2014 Aug;22(8):1530-43. doi: 10.1038/mt.2014.86. Epub 2014 May 15.

13.

Precompetitive activity to address the biological data needs of drug discovery.

Sidders B, Brockel C, Gutteridge A, Harland L, Jansen PG, McEwen R, Michalovich D, Seidel H, Weiss B, Williams-Jones B, Woodwark M.

Nat Rev Drug Discov. 2014 Feb;13(2):83-4. doi: 10.1038/nrd4230. No abstract available.

PMID:
24481293
14.

Molecular causes of transcriptional response: a Bayesian prior knowledge approach.

Zarringhalam K, Enayetallah A, Gutteridge A, Sidders B, Ziemek D.

Bioinformatics. 2013 Dec 15;29(24):3167-73. doi: 10.1093/bioinformatics/btt557. Epub 2013 Sep 26.

15.

Functional implications of ontogenetically and sexually dimorphic dentition in the eastern shovelnose ray, Aptychotrema rostrata.

Gutteridge AN, Bennett MB.

J Exp Biol. 2014 Jan 15;217(Pt 2):192-200. doi: 10.1242/jeb.089326. Epub 2013 Sep 26.

16.

Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution.

Humphries A, Cereser B, Gay LJ, Miller DS, Das B, Gutteridge A, Elia G, Nye E, Jeffery R, Poulsom R, Novelli MR, Rodriguez-Justo M, McDonald SA, Wright NA, Graham TA.

Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2490-9. doi: 10.1073/pnas.1220353110. Epub 2013 Jun 13.

17.

Novel pancreatic endocrine maturation pathways identified by genomic profiling and causal reasoning.

Gutteridge A, Rukstalis JM, Ziemek D, Tié M, Ji L, Ramos-Zayas R, Nardone NA, Norquay LD, Brenner MB, Tang K, McNeish JD, Rowntree RK.

PLoS One. 2013;8(2):e56024. doi: 10.1371/journal.pone.0056024. Epub 2013 Feb 13.

18.

Modelling the evolution of genetic instability during tumour progression.

S Datta R, Gutteridge A, Swanton C, Maley CC, Graham TA.

Evol Appl. 2013 Jan;6(1):20-33. doi: 10.1111/eva.12024. Epub 2012 Nov 26.

19.

Directing differentiation of human embryonic stem cells toward anterior neural ectoderm using small molecules.

Surmacz B, Fox H, Gutteridge A, Fish P, Lubitz S, Whiting P.

Stem Cells. 2012 Sep;30(9):1875-84. doi: 10.1002/stem.1166. Erratum in: Stem Cells. 2013 Jul;31(7):1446. Fish, Paul [added].

20.

The genetic control of growth rate: a systems biology study in yeast.

Pir P, Gutteridge A, Wu J, Rash B, Kell DB, Zhang N, Oliver SG.

BMC Syst Biol. 2012 Jan 13;6:4. doi: 10.1186/1752-0509-6-4.

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