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Results: 1 to 20 of 78

1.

RNA-seq of the aging brain in the short-lived fish N. furzeri - conserved pathways and novel genes associated with neurogenesis.

Baumgart M, Groth M, Priebe S, Savino A, Testa G, Dix A, Ripa R, Spallotta F, Gaetano C, Ori M, Terzibasi Tozzini E, Guthke R, Platzer M, Cellerino A.

Aging Cell. 2014 Jul 25. doi: 10.1111/acel.12257. [Epub ahead of print]

PMID:
25059688
[PubMed - as supplied by publisher]
Free Article
2.

Draft Genome Sequence of Streptomyces iranensis.

Horn F, Schroeckh V, Netzker T, Guthke R, Brakhage AA, Linde J.

Genome Announc. 2014 Jul 17;2(4). pii: e00616-14. doi: 10.1128/genomeA.00616-14.

PMID:
25035323
[PubMed]
Free PMC Article
3.

Novel application of multi-stimuli network inference to synovial fibroblasts of rheumatoid arthritis patients.

Kupfer P, Huber R, Weber M, Vlaic S, Häupl T, Koczan D, Guthke R, Kinne RW.

BMC Med Genomics. 2014 Jul 3;7:40. doi: 10.1186/1755-8794-7-40.

PMID:
24989895
[PubMed - in process]
Free PMC Article
4.

The novel globin protein fungoglobin is involved in low oxygen adaptation of Aspergillus fumigatus.

Hillmann F, Linde J, Beckmann N, Cyrulies M, Strassburger M, Heinekamp T, Haas H, Guthke R, Kniemeyer O, Brakhage AA.

Mol Microbiol. 2014 Aug;93(3):539-53. doi: 10.1111/mmi.12679. Epub 2014 Jul 7.

PMID:
24948085
[PubMed - in process]
5.

D-Glucosamine supplementation extends life span of nematodes and of ageing mice.

Weimer S, Priebs J, Kuhlow D, Groth M, Priebe S, Mansfeld J, Merry TL, Dubuis S, Laube B, Pfeiffer AF, Schulz TJ, Guthke R, Platzer M, Zamboni N, Zarse K, Ristow M.

Nat Commun. 2014 Apr 8;5:3563. doi: 10.1038/ncomms4563.

PMID:
24714520
[PubMed - in process]
Free PMC Article
6.

Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation.

Woetzel D, Huber R, Kupfer P, Pohlers D, Pfaff M, Driesch D, Häupl T, Koczan D, Stiehl P, Guthke R, Kinne RW.

Arthritis Res Ther. 2014 Apr 1;16(2):R84. doi: 10.1186/ar4526.

PMID:
24690414
[PubMed - in process]
Free PMC Article
7.

Integrated metabolic spatial-temporal model for the prediction of ammonia detoxification during liver damage and regeneration.

Schliess F, Hoehme S, Henkel SG, Ghallab A, Driesch D, Böttger J, Guthke R, Pfaff M, Hengstler JG, Gebhardt R, Häussinger D, Drasdo D, Zellmer S.

Hepatology. 2014 Mar 19. doi: 10.1002/hep.27136. [Epub ahead of print]

PMID:
24677161
[PubMed - as supplied by publisher]
8.

Regulatory networks controlling nitrogen sensing and uptake in Candida albicans.

Ramachandra S, Linde J, Brock M, Guthke R, Hube B, Brunke S.

PLoS One. 2014 Mar 20;9(3):e92734. doi: 10.1371/journal.pone.0092734. eCollection 2014.

PMID:
24651113
[PubMed - in process]
Free PMC Article
9.

Within-host influenza dynamics: a small-scale mathematical modeling approach.

Manchanda H, Seidel N, Krumbholz A, Sauerbrei A, Schmidtke M, Guthke R.

Biosystems. 2014 Apr;118:51-9. doi: 10.1016/j.biosystems.2014.02.004. Epub 2014 Mar 11.

PMID:
24614233
[PubMed - in process]
10.

Interactive exploration of integrated biological datasets using context-sensitive workflows.

Horn F, Rittweger M, Taubert J, Lysenko A, Rawlings C, Guthke R.

Front Genet. 2014 Feb 20;5:21. doi: 10.3389/fgene.2014.00021. eCollection 2014.

PMID:
24600467
[PubMed]
Free PMC Article
11.

Dynamic modelling of microRNA regulation during mesenchymal stem cell differentiation.

Weber M, Sotoca AM, Kupfer P, Guthke R, van Zoelen EJ.

BMC Syst Biol. 2013 Nov 12;7:124. doi: 10.1186/1752-0509-7-124.

PMID:
24219887
[PubMed - indexed for MEDLINE]
Free Article
12.

Extension of life span by impaired glucose metabolism in Caenorhabditis elegans is accompanied by structural rearrangements of the transcriptomic network.

Priebe S, Menzel U, Zarse K, Groth M, Platzer M, Ristow M, Guthke R.

PLoS One. 2013 Oct 30;8(10):e77776. doi: 10.1371/journal.pone.0077776. eCollection 2013.

PMID:
24204961
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Neuronal ROS signaling rather than AMPK/sirtuin-mediated energy sensing links dietary restriction to lifespan extension.

Schmeisser S, Priebe S, Groth M, Monajembashi S, Hemmerich P, Guthke R, Platzer M, Ristow M.

Mol Metab. 2013 Feb 14;2(2):92-102. doi: 10.1016/j.molmet.2013.02.002. eCollection 2013.

PMID:
24199155
[PubMed]
Free PMC Article
14.

Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

Schmeisser K, Mansfeld J, Kuhlow D, Weimer S, Priebe S, Heiland I, Birringer M, Groth M, Segref A, Kanfi Y, Price NL, Schmeisser S, Schuster S, Pfeiffer AF, Guthke R, Platzer M, Hoppe T, Cohen HY, Zarse K, Sinclair DA, Ristow M.

Nat Chem Biol. 2013 Nov;9(11):693-700. doi: 10.1038/nchembio.1352. Epub 2013 Sep 29.

PMID:
24077178
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A theoretical study of lipid accumulation in the liver-implications for nonalcoholic fatty liver disease.

Schleicher J, Guthke R, Dahmen U, Dirsch O, Holzhuetter HG, Schuster S.

Biochim Biophys Acta. 2014 Jan;1841(1):62-9. doi: 10.1016/j.bbalip.2013.08.016. Epub 2013 Aug 30.

PMID:
23999488
[PubMed - indexed for MEDLINE]
16.

Mitochondrial hormesis links low-dose arsenite exposure to lifespan extension.

Schmeisser S, Schmeisser K, Weimer S, Groth M, Priebe S, Fazius E, Kuhlow D, Pick D, Einax JW, Guthke R, Platzer M, Zarse K, Ristow M.

Aging Cell. 2013 Jun;12(3):508-17. doi: 10.1111/acel.12076. Epub 2013 May 6.

PMID:
23534459
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Inference of dynamical gene-regulatory networks based on time-resolved multi-stimuli multi-experiment data applying NetGenerator V2.0.

Weber M, Henkel SG, Vlaic S, Guthke R, van Zoelen EJ, Driesch D.

BMC Syst Biol. 2013 Jan 2;7:1. doi: 10.1186/1752-0509-7-1.

PMID:
23280066
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The extended TILAR approach: a novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes.

Vlaic S, Schmidt-Heck W, Matz-Soja M, Marbach E, Linde J, Meyer-Baese A, Zellmer S, Guthke R, Gebhardt R.

BMC Syst Biol. 2012 Nov 29;6:147. doi: 10.1186/1752-0509-6-147.

PMID:
23190768
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Comparison of transcriptome technologies in the pathogenic fungus Aspergillus fumigatus reveals novel insights into the genome and MpkA dependent gene expression.

Müller S, Baldin C, Groth M, Guthke R, Kniemeyer O, Brakhage AA, Valiante V.

BMC Genomics. 2012 Oct 2;13:519. doi: 10.1186/1471-2164-13-519.

PMID:
23031507
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Systems biology of microbial infection.

Guthke R, Linde J, Mech F, Figge MT.

Front Microbiol. 2012 Sep 12;3:328. doi: 10.3389/fmicb.2012.00328. eCollection 2012. No abstract available.

PMID:
22988447
[PubMed]
Free PMC Article

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