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Items: 1 to 20 of 107

1.

Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue.

Godoy P, Widera A, Schmidt-Heck W, Campos G, Meyer C, Cadenas C, Reif R, Stöber R, Hammad S, Pütter L, Gianmoena K, Marchan R, Ghallab A, Edlund K, Nüssler A, Thasler WE, Damm G, Seehofer D, Weiss TS, Dirsch O, Dahmen U, Gebhardt R, Chaudhari U, Meganathan K, Sachinidis A, Kelm J, Hofmann U, Zahedi RP, Guthke R, Blüthgen N, Dooley S, Hengstler JG.

Arch Toxicol. 2016 Jun 23. [Epub ahead of print]

PMID:
27339419
2.

Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis.

Matz-Soja M, Rennert C, Schönefeld K, Aleithe S, Boettger J, Schmidt-Heck W, Weiss TS, Hovhannisyan A, Zellmer S, Klöting N, Schulz A, Kratzsch J, Guthke R, Gebhardt R.

Elife. 2016 May 17;5. pii: e13308. doi: 10.7554/eLife.13308.

3.

Data-based Reconstruction of Gene Regulatory Networks of Fungal Pathogens.

Guthke R, Gerber S, Conrad T, Vlaic S, Durmuş S, Çakır T, Sevilgen FE, Shelest E, Linde J.

Front Microbiol. 2016 Apr 22;7:570. doi: 10.3389/fmicb.2016.00570. eCollection 2016.

4.

Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq.

Marthandan S, Baumgart M, Priebe S, Groth M, Schaer J, Kaether C, Guthke R, Cellerino A, Platzer M, Diekmann S, Hemmerich P.

PLoS One. 2016 May 3;11(5):e0154531. doi: 10.1371/journal.pone.0154531. eCollection 2016.

5.

Longitudinal RNA-Seq Analysis of Vertebrate Aging Identifies Mitochondrial Complex I as a Small-Molecule-Sensitive Modifier of Lifespan.

Baumgart M, Priebe S, Groth M, Hartmann N, Menzel U, Pandolfini L, Koch P, Felder M, Ristow M, Englert C, Guthke R, Platzer M, Cellerino A.

Cell Syst. 2016 Feb 24;2(2):122-32. doi: 10.1016/j.cels.2016.01.014. Epub 2016 Feb 24.

6.

Use of systems biology to decipher host-pathogen interaction networks and predict biomarkers.

Dix A, Vlaic S, Guthke R, Linde J.

Clin Microbiol Infect. 2016 Apr 22. pii: S1198-743X(16)30073-8. doi: 10.1016/j.cmi.2016.04.014. [Epub ahead of print] Review.

7.

How to Predict Molecular Interactions between Species?

Schulze S, Schleicher J, Guthke R, Linde J.

Front Microbiol. 2016 Mar 31;7:442. doi: 10.3389/fmicb.2016.00442. eCollection 2016. Review.

8.

Genome-Wide Expression Profiling Reveals S100B as Biomarker for Invasive Aspergillosis.

Dix A, Czakai K, Springer J, Fliesser M, Bonin M, Guthke R, Schmitt AL, Einsele H, Linde J, Löffler J.

Front Microbiol. 2016 Mar 21;7:320. doi: 10.3389/fmicb.2016.00320. eCollection 2016.

9.

Proteomic Profiling of Serological Responses to Aspergillus fumigatus Antigens in Patients with Invasive Aspergillosis.

Teutschbein J, Simon S, Lother J, Springer J, Hortschansky P, Morton CO, Löffler J, Einsele H, Conneally E, Rogers TR, Guthke R, Brakhage AA, Kniemeyer O.

J Proteome Res. 2016 May 6;15(5):1580-91. doi: 10.1021/acs.jproteome.6b00042. Epub 2016 Mar 24.

PMID:
26974881
10.

Draft Genome Sequences of Fungus Aspergillus calidoustus.

Horn F, Linde J, Mattern DJ, Walther G, Guthke R, Scherlach K, Martin K, Brakhage AA, Petzke L, Valiante V.

Genome Announc. 2016 Mar 10;4(2). pii: e00102-16. doi: 10.1128/genomeA.00102-16.

11.

Editorial: Computational Systems Biology of Pathogen-Host Interactions.

Durmuş S, Çakır T, Guthke R.

Front Microbiol. 2016 Feb 4;7:21. doi: 10.3389/fmicb.2016.00021. eCollection 2016. No abstract available.

12.

Facing the challenges of multiscale modelling of bacterial and fungal pathogen-host interactions.

Schleicher J, Conrad T, Gustafsson M, Cedersund G, Guthke R, Linde J.

Brief Funct Genomics. 2016 Feb 8. pii: elv064. [Epub ahead of print]

13.

Candida albicans infection leads to barrier breakdown and a MAPK/NF-κB mediated stress response in the intestinal epithelial cell line C2BBe1.

Böhringer M, Pohlers S, Schulze S, Albrecht-Eckardt D, Piegsa J, Weber M, Martin R, Hünniger K, Linde J, Guthke R, Kurzai O.

Cell Microbiol. 2016 Jul;18(7):889-904. doi: 10.1111/cmi.12566. Epub 2016 Feb 26.

PMID:
26752615
14.

Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.

Mansfeld J, Urban N, Priebe S, Groth M, Frahm C, Hartmann N, Gebauer J, Ravichandran M, Dommaschk A, Schmeisser S, Kuhlow D, Monajembashi S, Bremer-Streck S, Hemmerich P, Kiehntopf M, Zamboni N, Englert C, Guthke R, Kaleta C, Platzer M, Sühnel J, Witte OW, Zarse K, Ristow M.

Nat Commun. 2015 Dec 1;6:10043. doi: 10.1038/ncomms10043.

15.

Hormetic effect of rotenone in primary human fibroblasts.

Marthandan S, Priebe S, Groth M, Guthke R, Platzer M, Hemmerich P, Diekmann S.

Immun Ageing. 2015 Sep 16;12:11. doi: 10.1186/s12979-015-0038-8. eCollection 2015.

16.

Network Modeling Reveals Cross Talk of MAP Kinases during Adaptation to Caspofungin Stress in Aspergillus fumigatus.

Altwasser R, Baldin C, Weber J, Guthke R, Kniemeyer O, Brakhage AA, Linde J, Valiante V.

PLoS One. 2015 Sep 10;10(9):e0136932. doi: 10.1371/journal.pone.0136932. eCollection 2015.

17.

Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts.

Marthandan S, Priebe S, Baumgart M, Groth M, Cellerino A, Guthke R, Hemmerich P, Diekmann S.

Biomed Res Int. 2015;2015:731938. doi: 10.1155/2015/731938. Epub 2015 Aug 3.

18.

Draft Genome Sequence of the Fungus Penicillium brasilianum MG11.

Horn F, Linde J, Mattern DJ, Walther G, Guthke R, Brakhage AA, Valiante V.

Genome Announc. 2015 Sep 3;3(5). pii: e00724-15. doi: 10.1128/genomeA.00724-15.

19.

Computing the various pathways of penicillin synthesis and their molar yields.

Prauße MT, Schäuble S, Guthke R, Schuster S.

Biotechnol Bioeng. 2016 Jan;113(1):173-81. doi: 10.1002/bit.25694. Epub 2015 Aug 19.

PMID:
26134880
20.

Fuzzy modeling reveals a dynamic self-sustaining network of the GLI transcription factors controlling important metabolic regulators in adult mouse hepatocytes.

Schmidt-Heck W, Matz-Soja M, Aleithe S, Marbach E, Guthke R, Gebhardt R.

Mol Biosyst. 2015 Aug;11(8):2190-7. doi: 10.1039/c5mb00129c.

PMID:
26010061
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