Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 1 to 20 of 280

1.

Tropomyosin Promotes Lamellipodial Persistence by Collaborating with Arp2/3 at the Leading Edge.

Brayford S, Bryce NS, Schevzov G, Haynes EM, Bear JE, Hardeman EC, Gunning PW.

Curr Biol. 2016 Apr 20. pii: S0960-9822(16)30204-4. doi: 10.1016/j.cub.2016.03.028. [Epub ahead of print]

PMID:
27112294
2.

Understanding Protein-Protein Interactions: Essential Players in (Patho)physiology (Part 2).

Wilson AJ, Gunning PT.

ChemMedChem. 2016 Apr 19;11(8):732-3. doi: 10.1002/cmdc.201600158. Epub 2016 Apr 9.

PMID:
27061459
3.

Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities.

Ali AM, Gómez-Biagi RF, Rosa DA, Lai PS, Heaton WL, Park JS, Eiring AM, Vellore NA, de Araujo ED, Ball DP, Shouksmith AE, Patel AB, Deininger MW, O'Hare T, Gunning PT.

ChemMedChem. 2016 Apr 19;11(8):850-61. doi: 10.1002/cmdc.201600021. Epub 2016 Mar 30.

PMID:
27028877
4.

Understanding Protein-Protein Interactions: Essential Players in (Patho)physiology (Part 1).

Wilson AJ, Gunning PT.

Chembiochem. 2016 Apr 15;17(8):644-5. doi: 10.1002/cbic.201600166. Epub 2016 Mar 30.

PMID:
27027879
5.

STAT3 inhibitor has potent antitumor activity in B-lineage acute lymphoblastic leukemia cells overexpressing the high mobility group A1 (HMGA1)-STAT3 pathway.

Belton A, Xian L, Huso T, Koo M, Luo LZ, Turkson J, Page BD, Gunning PT, Liu G, Huso DL, Resar LM.

Leuk Lymphoma. 2016 Mar 8:1-4. [Epub ahead of print] No abstract available.

PMID:
26952843
6.

Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent.

Ball DP, Lewis AM, Williams D, Resetca D, Wilson DJ, Gunning PT.

Oncotarget. 2016 Mar 2. doi: 10.18632/oncotarget.7838. [Epub ahead of print]

7.

'Venus trapped, Mars transits': Cu and Fe redox chemistry, cellular topography and in situ ligand binding in terrestrial isopod hepatopancreas.

Kille P, Morgan AJ, Powell K, Mosselmans JF, Hart D, Gunning P, Hayes A, Scarborough D, McDonald I, Charnock JM.

Open Biol. 2016 Mar;6(3). pii: 150270. doi: 10.1098/rsob.150270.

8.

Enhancement of accelerated carbonation of alkaline waste residues by ultrasound.

Araizi PK, Hills CD, Maries A, Gunning PJ, Wray DS.

Waste Manag. 2016 Apr;50:121-9. doi: 10.1016/j.wasman.2016.01.006. Epub 2016 Feb 19.

PMID:
26905698
9.

Applying Small Molecule Signal Transducer and Activator of Trancription-3 (STAT3) Protein Inhibitors as Pancreatic Cancer Therapeutics.

Arpin CC, Mac S, Jiang Y, Cheng H, Grimard M, Page BD, Kamocka MM, Haftchenary S, Su H, Ball DP, Rosa DA, Lai PS, Gomez-Biagi RF, Ali AM, Rana R, Hanenberg H, Kerman K, McElyea KC, Sandusky GE, Gunning PT, Fishel ML.

Mol Cancer Ther. 2016 Feb 12. pii: molcanther.0003.2015. [Epub ahead of print]

PMID:
26873728
10.

STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion.

Gotthardt D, Putz EM, Grundschober E, Prchal-Murphy M, Straka E, Kudweis P, Heller G, Bago-Horvath Z, Witalisz-Siepracka A, Cumaraswamy AA, Gunning PT, Strobl B, Müller M, Moriggl R, Stockmann C, Sexl V.

Cancer Discov. 2016 Apr;6(4):414-29. doi: 10.1158/2159-8290.CD-15-0732. Epub 2016 Feb 12.

PMID:
26873347
11.

A small molecule inhibitor of tropomyosin dissociates actin binding from tropomyosin-directed regulation of actin dynamics.

Bonello TT, Janco M, Hook J, Byun A, Appaduray M, Dedova I, Hitchcock-DeGregori S, Hardeman EC, Stehn JR, Böcking T, Gunning PW.

Sci Rep. 2016 Jan 25;6:19816. doi: 10.1038/srep19816.

12.

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue.

Erami Z, Herrmann D, Warren SC, Nobis M, McGhee EJ, Lucas MC, Leung W, Reischmann N, Mrowinska A, Schwarz JP, Kadir S, Conway JR, Vennin C, Karim SA, Campbell AD, Gallego-Ortega D, Magenau A, Murphy KJ, Ridgway RA, Law AM, Walters SN, Grey ST, Croucher DR, Zhang L, Herzog H, Hardeman EC, Gunning PW, Ormandy CJ, Evans TR, Strathdee D, Sansom OJ, Morton JP, Anderson KI, Timpson P.

Cell Rep. 2016 Jan 5;14(1):152-67. doi: 10.1016/j.celrep.2015.12.020. Epub 2015 Dec 24.

13.

An Actin Filament Population Defined by the Tropomyosin Tpm3.1 Regulates Glucose Uptake.

Kee AJ, Yang L, Lucas CA, Greenberg MJ, Martel N, Leong GM, Hughes WE, Cooney GJ, James DE, Ostap EM, Han W, Gunning PW, Hardeman EC.

Traffic. 2016 Jan;17(1):80-1. doi: 10.1111/tra.12342. No abstract available.

PMID:
26688443
14.

Total ellipse of the heart valve: the impact of eccentric stent distortion on the regional dynamic deformation of pericardial tissue leaflets of a transcatheter aortic valve replacement.

Gunning PS, Saikrishnan N, Yoganathan AP, McNamara LM.

J R Soc Interface. 2015 Dec 6;12(113):20150737. doi: 10.1098/rsif.2015.0737.

PMID:
26674192
15.

A tool for the selective sequestration of ATP and PPi to aid in-solution phosphopeptide detection assays.

Duodu E, Kraskouskaya D, Gómez-Biagi RF, Gunning PT.

Analyst. 2016 Feb 7;141(3):820-2. doi: 10.1039/c5an01414j. Epub 2015 Dec 8.

PMID:
26643551
16.

Treatment With Diet and Exercise for Women With Gestational Diabetes Mellitus Diagnosed Using IADPSG Criteria.

Kgosidialwa O, Egan AM, Carmody L, Kirwan B, Gunning P, Dunne FP.

J Clin Endocrinol Metab. 2015 Dec;100(12):4629-36. doi: 10.1210/jc.2015-3259. Epub 2015 Oct 23.

PMID:
26495752
17.

Hypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells.

Glass JJ, Phillips PA, Gunning PW, Stehn JR.

BMC Cancer. 2015 Oct 16;15:712. doi: 10.1186/s12885-015-1741-8.

18.

Identification of Bidentate Salicylic Acid Inhibitors of PTP1B.

Haftchenary S, Jouk AO, Aubry I, Lewis AM, Landry M, Ball DP, Shouksmith AE, Collins CV, Tremblay ML, Gunning PT.

ACS Med Chem Lett. 2015 Jul 22;6(9):982-6. doi: 10.1021/acsmedchemlett.5b00171. eCollection 2015 Sep 10.

PMID:
26396684
19.

A STAT inhibitor patent review: progress since 2011.

Lai PS, Rosa DA, Magdy Ali A, Gómez-Biagi RF, Ball DP, Shouksmith AE, Gunning PT.

Expert Opin Ther Pat. 2015;25(12):1397-421. doi: 10.1517/13543776.2015.1086749. Epub 2015 Sep 22. Erratum in: Expert Opin Ther Pat. 2015;25(12):1495.

PMID:
26394986
20.

Practical and cost-effective high-fidelity optical carrier dissemination using coherent communication techniques.

Sooudi E, O'Gorman J, Gunning P, Ellis AD, Gunning FC, Manning RJ.

Opt Express. 2015 Aug 24;23(17):21678-89. doi: 10.1364/OE.23.021678.

PMID:
26368147
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Loading ...
Write to the Help Desk