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Results: 6


Identification of regulatory structure and kinetic parameters of biochemical networks via mixed-integer dynamic optimization.

Guillén-Gosálbez G, Miró A, Alves R, Sorribas A, Jiménez L.

BMC Syst Biol. 2013 Oct 31;7:113. doi: 10.1186/1752-0509-7-113.


Identifying the preferred subset of enzymatic profiles in nonlinear kinetic metabolic models via multiobjective global optimization and Pareto filters.

Pozo C, Guillén-Gosálbez G, Sorribas A, Jiménez L.

PLoS One. 2012;7(9):e43487. doi: 10.1371/journal.pone.0043487. Epub 2012 Sep 20.


Deterministic global optimization algorithm based on outer approximation for the parameter estimation of nonlinear dynamic biological systems.

Miró A, Pozo C, Guillén-Gosálbez G, Egea JA, Jiménez L.

BMC Bioinformatics. 2012 May 10;13:90. doi: 10.1186/1471-2105-13-90.


Steady-state global optimization of metabolic non-linear dynamic models through recasting into power-law canonical models.

Pozo C, Marín-Sanguino A, Alves R, Guillén-Gosálbez G, Jiménez L, Sorribas A.

BMC Syst Biol. 2011 Aug 25;5:137. doi: 10.1186/1752-0509-5-137.


Optimization and evolution in metabolic pathways: global optimization techniques in Generalized Mass Action models.

Sorribas A, Pozo C, Vilaprinyo E, Guillén-Gosálbez G, Jiménez L, Alves R.

J Biotechnol. 2010 Sep 1;149(3):141-53. doi: 10.1016/j.jbiotec.2010.01.026. Epub 2010 Feb 10.

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