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Results: 1 to 20 of 69

1.

Knockdown of platinum-induced growth differentiation factor 15 abrogates p27-mediated tumor growth delay in the chemoresistant ovarian cancer model A2780cis.

Meier JC, Haendler B, Seidel H, Groth P, Adams R, Ziegelbauer K, Kreft B, Beckmann G, Sommer A, Kopitz C.

Cancer Med. 2014 Dec 10. doi: 10.1002/cam4.354. [Epub ahead of print]

PMID:
25490861
[PubMed - as supplied by publisher]
2.

Drug discovery FAQs: workflows for answering multidomain drug discovery questions.

Chichester C, Digles D, Siebes R, Loizou A, Groth P, Harland L.

Drug Discov Today. 2014 Nov 20. pii: S1359-6446(14)00443-7. doi: 10.1016/j.drudis.2014.11.006. [Epub ahead of print]

PMID:
25463038
[PubMed - as supplied by publisher]
Free Article
3.

BRCA2 and RAD51 promote double-strand break formation and cell death in response to gemcitabine.

Jones RM, Kotsantis P, Stewart GS, Groth P, Petermann E.

Mol Cancer Ther. 2014 Oct;13(10):2412-21. doi: 10.1158/1535-7163.MCT-13-0862. Epub 2014 Jul 22.

PMID:
25053826
[PubMed - in process]
4.

Ten simple rules for the care and feeding of scientific data.

Goodman A, Pepe A, Blocker AW, Borgman CL, Cranmer K, Crosas M, Di Stefano R, Gil Y, Groth P, Hedstrom M, Hogg DW, Kashyap V, Mahabal A, Siemiginowska A, Slavkovic A.

PLoS Comput Biol. 2014 Apr 24;10(4):e1003542. doi: 10.1371/journal.pcbi.1003542. eCollection 2014 Apr. No abstract available.

PMID:
24763340
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Prediction errors in learning drug response from gene expression data - influence of labeling, sample size, and machine learning algorithm.

Bayer I, Groth P, Schneckener S.

PLoS One. 2013 Jul 23;8(7):e70294. doi: 10.1371/journal.pone.0070294. Print 2013.

PMID:
23894636
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Replication stress links structural and numerical cancer chromosomal instability.

Burrell RA, McClelland SE, Endesfelder D, Groth P, Weller MC, Shaikh N, Domingo E, Kanu N, Dewhurst SM, Gronroos E, Chew SK, Rowan AJ, Schenk A, Sheffer M, Howell M, Kschischo M, Behrens A, Helleday T, Bartek J, Tomlinson IP, Swanton C.

Nature. 2013 Feb 28;494(7438):492-6. doi: 10.1038/nature11935. Erratum in: Nature. 2013 Aug 22;500(7463):490.

PMID:
23446422
[PubMed - indexed for MEDLINE]
7.

Genome Fusion Detection: a novel method to detect fusion genes from SNP-array data.

Thieme S, Groth P.

Bioinformatics. 2013 Mar 15;29(6):671-7. doi: 10.1093/bioinformatics/btt028. Epub 2013 Jan 22.

PMID:
23341502
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The altmetrics collection.

Priem J, Groth P, Taraborelli D.

PLoS One. 2012;7(11):e48753. doi: 10.1371/journal.pone.0048753. Epub 2012 Nov 1. No abstract available.

PMID:
23133655
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

DNA interstrand crosslinks induce a potent replication block followed by formation and repair of double strand breaks in intact mammalian cells.

Vare D, Groth P, Carlsson R, Johansson F, Erixon K, Jenssen D.

DNA Repair (Amst). 2012 Dec 1;11(12):976-85. doi: 10.1016/j.dnarep.2012.09.010. Epub 2012 Oct 23.

PMID:
23099010
[PubMed - indexed for MEDLINE]
10.

Open PHACTS: semantic interoperability for drug discovery.

Williams AJ, Harland L, Groth P, Pettifer S, Chichester C, Willighagen EL, Evelo CT, Blomberg N, Ecker G, Goble C, Mons B.

Drug Discov Today. 2012 Nov;17(21-22):1188-98. doi: 10.1016/j.drudis.2012.05.016. Epub 2012 Jun 7. Review.

PMID:
22683805
[PubMed - indexed for MEDLINE]
Free Article
11.

Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation.

Groth P, Orta ML, Elvers I, Majumder MM, Lagerqvist A, Helleday T.

Nucleic Acids Res. 2012 Aug;40(14):6585-94. doi: 10.1093/nar/gks315. Epub 2012 Apr 13.

PMID:
22505579
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Phenotype mining for functional genomics and gene discovery.

Groth P, Leser U, Weiss B.

Methods Mol Biol. 2011;760:159-73. doi: 10.1007/978-1-61779-176-5_10.

PMID:
21779996
[PubMed - indexed for MEDLINE]
13.

Influence of tropospheric ozone control on exposure to ultraviolet radiation at the surface.

Madronich S, Wagner M, Groth P.

Environ Sci Technol. 2011 Aug 15;45(16):6919-23. doi: 10.1021/es200701q. Epub 2011 Jul 21.

PMID:
21755973
[PubMed - indexed for MEDLINE]
14.

The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.

Baigent C, Landray MJ, Reith C, Emberson J, Wheeler DC, Tomson C, Wanner C, Krane V, Cass A, Craig J, Neal B, Jiang L, Hooi LS, Levin A, Agodoa L, Gaziano M, Kasiske B, Walker R, Massy ZA, Feldt-Rasmussen B, Krairittichai U, Ophascharoensuk V, Fellström B, Holdaas H, Tesar V, Wiecek A, Grobbee D, de Zeeuw D, Grönhagen-Riska C, Dasgupta T, Lewis D, Herrington W, Mafham M, Majoni W, Wallendszus K, Grimm R, Pedersen T, Tobert J, Armitage J, Baxter A, Bray C, Chen Y, Chen Z, Hill M, Knott C, Parish S, Simpson D, Sleight P, Young A, Collins R; SHARP Investigators.

Lancet. 2011 Jun 25;377(9784):2181-92. doi: 10.1016/S0140-6736(11)60739-3. Epub 2011 Jun 12.

PMID:
21663949
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

UV stalled replication forks restart by re-priming in human fibroblasts.

Elvers I, Johansson F, Groth P, Erixon K, Helleday T.

Nucleic Acids Res. 2011 Sep 1;39(16):7049-57. doi: 10.1093/nar/gkr420. Epub 2011 Jun 6.

PMID:
21646340
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The value of data.

Mons B, van Haagen H, Chichester C, Hoen PB, den Dunnen JT, van Ommen G, van Mulligen E, Singh B, Hooft R, Roos M, Hammond J, Kiesel B, Giardine B, Velterop J, Groth P, Schultes E.

Nat Genet. 2011 Mar 29;43(4):281-3. doi: 10.1038/ng0411-281.

PMID:
21445068
[PubMed - indexed for MEDLINE]
17.

National housing and impervious surface scenarios for integrated climate impact assessments.

Bierwagen BG, Theobald DM, Pyke CR, Choate A, Groth P, Thomas JV, Morefield P.

Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):20887-92. doi: 10.1073/pnas.1002096107. Epub 2010 Nov 15.

PMID:
21078956
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Primary tumour size is a prognostic parameter in patients suffering from differentiated thyroid carcinoma with extrathyroidal growth: results of the MSDS trial.

Krämer JA, Schmid KW, Dralle H, Dietlein M, Schicha H, Lerch H, Gerss J, Frankewitsch T, Schober O, Riemann B; MSDS study group.

Eur J Endocrinol. 2010 Oct;163(4):637-44. doi: 10.1530/EJE-10-0116. Epub 2010 Jul 21.

PMID:
20660003
[PubMed - indexed for MEDLINE]
Free Article
19.

Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage.

Groth P, Ausländer S, Majumder MM, Schultz N, Johansson F, Petermann E, Helleday T.

J Mol Biol. 2010 Sep 10;402(1):70-82. doi: 10.1016/j.jmb.2010.07.010. Epub 2010 Jul 17.

PMID:
20643142
[PubMed - indexed for MEDLINE]
20.

Phenoclustering: online mining of cross-species phenotypes.

Groth P, Kalev I, Kirov I, Traikov B, Leser U, Weiss B.

Bioinformatics. 2010 Aug 1;26(15):1924-5. doi: 10.1093/bioinformatics/btq311. Epub 2010 Jun 18.

PMID:
20562418
[PubMed - indexed for MEDLINE]
Free PMC Article

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