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Regulation of osteosarcoma cell lung metastasis by the c-Fos/AP-1 target FGFR1.

Weekes D, Kashima TG, Zandueta C, Perurena N, Thomas DP, Sunters A, Vuillier C, Bozec A, El-Emir E, Miletich I, Patiño-Garcia A, Lecanda F, Grigoriadis AE.

Oncogene. 2016 Jun 2;35(22):2948. doi: 10.1038/onc.2015.420. No abstract available.


Targeting folate receptor alpha for cancer treatment.

Cheung A, Bax HJ, Josephs DH, Ilieva KM, Pellizzari G, Opzoomer J, Bloomfield J, Fittall M, Grigoriadis A, Figini M, Canevari S, Spicer JF, Tutt AN, Karagiannis SN.

Oncotarget. 2016 May 27. doi: 10.18632/oncotarget.9651. [Epub ahead of print] Review.


Matrix-Gla protein promotes osteosarcoma lung metastasis and associates with poor prognosis.

Zandueta C, Ormazábal C, Perurena N, Martínez-Canarias S, Zalacaín M, San Julián M, Grigoriadis AE, Valencia K, Campos-Laborie FJ, Rivas JL, Vicent S, Patiño-García A, Lecanda F.

J Pathol. 2016 May 12. doi: 10.1002/path.4740. [Epub ahead of print]


Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B.

Akre MK, Starrett GJ, Quist JS, Temiz NA, Carpenter MA, Tutt AN, Grigoriadis A, Harris RS.

PLoS One. 2016 May 10;11(5):e0155391. doi: 10.1371/journal.pone.0155391. eCollection 2016.


Small Molecule Inhibition of Transforming Growth Factor Beta Signaling Enables the Endogenous Regenerative Potential of the Mammalian Calvarium.

Senarath-Yapa K, Li S, Walmsley GG, Zielins E, Paik K, Britto JA, Grigoriadis AE, Wan DC, Liu KJ, Longaker MT, Quarto N.

Tissue Eng Part A. 2016 May;22(9-10):707-20. doi: 10.1089/ten.TEA.2015.0527. Epub 2016 Apr 26.


Multidetector CT of pancreatic ductal adenocarcinoma: Effect of tube voltage and iodine load on tumour conspicuity and image quality.

Loizou L, Albiin N, Leidner B, Axelsson E, Fischer MA, Grigoriadis A, Del Chiaro M, Segersvärd R, Verbeke C, Sundin A, Kartalis N.

Eur Radiol. 2016 Mar 10. [Epub ahead of print]


Big Data: the challenge for small research groups in the era of cancer genomics.

Noor AM, Holmberg L, Gillett C, Grigoriadis A.

Br J Cancer. 2015 Nov 17;113(10):1405-12. doi: 10.1038/bjc.2015.341. Epub 2015 Oct 22. Review.


Root and Eruption Defects in c-Fos Mice Are Driven by Loss of Osteoclasts.

Alfaqeeh S, Oralova V, Foxworthy M, Matalova E, Grigoriadis AE, Tucker AS.

J Dent Res. 2015 Dec;94(12):1724-31. doi: 10.1177/0022034515608828. Epub 2015 Oct 6.


Regulation of osteosarcoma cell lung metastasis by the c-Fos/AP-1 target FGFR1.

Weekes D, Kashima TG, Zandueta C, Perurena N, Thomas DP, Sunters A, Vuillier C, Bozec A, El-Emir E, Miletich I, Patiño-Garcia A, Lecanda F, Grigoriadis AE.

Oncogene. 2016 Jun 2;35(22):2852-61. doi: 10.1038/onc.2015.344. Epub 2015 Sep 21.


Selection and evolution in the genomic landscape of copy number alterations in ductal carcinoma in situ (DCIS) and its progression to invasive carcinoma of ductal/no special type: a meta-analysis.

Rane SU, Mirza H, Grigoriadis A, Pinder SE.

Breast Cancer Res Treat. 2015 Aug;153(1):101-21. doi: 10.1007/s10549-015-3509-x. Epub 2015 Aug 9.


Digital imaging in the immunohistochemical evaluation of the proliferation markers Ki67, MCM2 and Geminin, in early breast cancer, and their putative prognostic value.

Joshi S, Watkins J, Gazinska P, Brown JP, Gillett CE, Grigoriadis A, Pinder SE.

BMC Cancer. 2015 Jul 25;15:546. doi: 10.1186/s12885-015-1531-3.


Perfusion computed tomography for detection of hepatocellular carcinoma in patients with liver cirrhosis.

Fischer MA, Kartalis N, Grigoriadis A, Loizou L, Stål P, Leidner B, Aspelin P, Brismar TB.

Eur Radiol. 2015 Nov;25(11):3123-32. doi: 10.1007/s00330-015-3732-1. Epub 2015 Apr 23.


Mouse mammary stem cells express prognostic markers for triple-negative breast cancer.

Soady KJ, Kendrick H, Gao Q, Tutt A, Zvelebil M, Ordonez LD, Quist J, Tan DW, Isacke CM, Grigoriadis A, Smalley MJ.

Breast Cancer Res. 2015 Mar 4;17:31. doi: 10.1186/s13058-015-0539-6.


Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms.

Schouten PC, Grigoriadis A, Kuilman T, Mirza H, Watkins JA, Cooke SA, van Dyk E, Severson TM, Rueda OM, Hoogstraat M, Verhagen CV, Natrajan R, Chin SF, Lips EH, Kruizinga J, Velds A, Nieuwland M, Kerkhoven RM, Krijgsman O, Vens C, Peeper D, Nederlof PM, Caldas C, Tutt AN, Wessels LF, Linn SC.

Mol Oncol. 2015 Aug;9(7):1274-86. doi: 10.1016/j.molonc.2015.03.002. Epub 2015 Mar 20.


Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers.

Watkins J, Weekes D, Shah V, Gazinska P, Joshi S, Sidhu B, Gillett C, Pinder S, Vanoli F, Jasin M, Mayrhofer M, Isaksson A, Cheang MC, Mirza H, Frankum J, Lord CJ, Ashworth A, Vinayak S, Ford JM, Telli ML, Grigoriadis A, Tutt AN.

Cancer Discov. 2015 May;5(5):488-505. doi: 10.1158/2159-8290.CD-14-1092. Epub 2015 Mar 13.


Genomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancers.

Watkins JA, Irshad S, Grigoriadis A, Tutt AN.

Breast Cancer Res. 2014 Jun 3;16(3):211. doi: 10.1186/bcr3670. Review.


IL15RA drives antagonistic mechanisms of cancer development and immune control in lymphocyte-enriched triple-negative breast cancers.

Marra P, Mathew S, Grigoriadis A, Wu Y, Kyle-Cezar F, Watkins J, Rashid M, De Rinaldis E, Hessey S, Gazinska P, Hayday A, Tutt A.

Cancer Res. 2014 Sep 1;74(17):4908-21. doi: 10.1158/0008-5472.CAN-14-0637. Epub 2014 Jun 30.


Identification of a gene regulatory network associated with prion replication.

Marbiah MM, Harvey A, West BT, Louzolo A, Banerjee P, Alden J, Grigoriadis A, Hummerich H, Kan HM, Cai Y, Bloom GS, Jat P, Collinge J, Klöhn PC.

EMBO J. 2014 Jul 17;33(14):1527-47. doi: 10.15252/embj.201387150. Epub 2014 May 19.


Immunological visibility: posttranscriptional regulation of human NKG2D ligands by the EGF receptor pathway.

Vantourout P, Willcox C, Turner A, Swanson CM, Haque Y, Sobolev O, Grigoriadis A, Tutt A, Hayday A.

Sci Transl Med. 2014 Apr 9;6(231):231ra49. doi: 10.1126/scitranslmed.3007579.


Temporal profile and amplitude of human masseter muscle activity is adapted to food properties during individual chewing cycles.

Grigoriadis A, Johansson RS, Trulsson M.

J Oral Rehabil. 2014 May;41(5):367-73. doi: 10.1111/joor.12155. Epub 2014 Mar 10.

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