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Results: 1 to 20 of 94

1.

Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding.

Cetica V, Hackmann Y, Grieve S, Sieni E, Ciambotti B, Coniglio ML, Pende D, Gilmour K, Romagnoli P, Griffiths GM, Aricò M.

J Allergy Clin Immunol. 2014 Oct 10. pii: S0091-6749(14)01263-9. doi: 10.1016/j.jaci.2014.08.039. [Epub ahead of print]

PMID:
25312756
[PubMed - as supplied by publisher]
Free Article
2.

The biogenesis of lysosomes and lysosome-related organelles.

Luzio JP, Hackmann Y, Dieckmann NM, Griffiths GM.

Cold Spring Harb Perspect Biol. 2014 Sep 2;6(9):a016840. doi: 10.1101/cshperspect.a016840.

PMID:
25183830
[PubMed - in process]
3.

Communication, the centrosome and the immunological synapse.

Stinchcombe JC, Griffiths GM.

Philos Trans R Soc Lond B Biol Sci. 2014 Sep 5;369(1650). pii: 20130463. doi: 10.1098/rstb.2013.0463.

PMID:
25047617
[PubMed - in process]
Free PMC Article
4.

Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis.

Meazza R, Tuberosa C, Cetica V, Falco M, Parolini S, Grieve S, Griffiths GM, Sieni E, Marcenaro S, Micalizzi C, Montin D, Fagioli F, Moretta A, Mingari MC, Moretta L, Notarangelo LD, Bottino C, Aricò M, Pende D.

J Allergy Clin Immunol. 2014 Dec;134(6):1381-1387.e7. doi: 10.1016/j.jaci.2014.04.043. Epub 2014 Jun 27.

PMID:
24985396
[PubMed - in process]
5.

Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL.

Jenkins MR, Stinchcombe JC, Au-Yeung BB, Asano Y, Ritter AT, Weiss A, Griffiths GM.

Elife. 2014 Mar 4;3:e01310. doi: 10.7554/eLife.01310.

PMID:
24596147
[PubMed - in process]
Free PMC Article
6.

Hedgehog signaling controls T cell killing at the immunological synapse.

de la Roche M, Ritter AT, Angus KL, Dinsmore C, Earnshaw CH, Reiter JF, Griffiths GM.

Science. 2013 Dec 6;342(6163):1247-50. doi: 10.1126/science.1244689.

PMID:
24311692
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Syntaxin binding mechanism and disease-causing mutations in Munc18-2.

Hackmann Y, Graham SC, Ehl S, Höning S, Lehmberg K, Aricò M, Owen DJ, Griffiths GM.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4482-91. doi: 10.1073/pnas.1313474110. Epub 2013 Nov 5.

PMID:
24194549
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The role of the cytoskeleton at the immunological synapse.

Ritter AT, Angus KL, Griffiths GM.

Immunol Rev. 2013 Nov;256(1):107-17. doi: 10.1111/imr.12117. Review.

PMID:
24117816
[PubMed - indexed for MEDLINE]
Free Article
9.

Open questions: missing pieces from the immunological jigsaw puzzle.

Griffiths GM.

BMC Biol. 2013 Jan 31;11:10. doi: 10.1186/1741-7007-11-10. No abstract available.

PMID:
23369631
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency.

Lang PA, Shaabani N, Borkens S, Honke N, Scheu S, Booth S, Brenner D, Meryk A, Barthuber C, Recher M, Mak TW, Ohashi PS, Häussinger D, Griffiths GM, Thrasher AJ, Bouma G, Lang KS.

J Allergy Clin Immunol. 2013 Mar;131(3):815-24. doi: 10.1016/j.jaci.2012.08.050. Epub 2012 Nov 6.

PMID:
23141740
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Syntaxin 11 is required for NK and CD8⁺ T-cell cytotoxicity and neutrophil degranulation.

D'Orlando O, Zhao F, Kasper B, Orinska Z, Müller J, Hermans-Borgmeyer I, Griffiths GM, Zur Stadt U, Bulfone-Paus S.

Eur J Immunol. 2013 Jan;43(1):194-208. doi: 10.1002/eji.201142343. Epub 2012 Dec 12.

PMID:
23042080
[PubMed - indexed for MEDLINE]
12.

Cell polarisation and the immunological synapse.

Angus KL, Griffiths GM.

Curr Opin Cell Biol. 2013 Feb;25(1):85-91. doi: 10.1016/j.ceb.2012.08.013. Epub 2012 Sep 16. Review.

PMID:
22990072
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Cytotoxic T lymphocyte effector function is independent of nucleus-centrosome dissociation.

Lui-Roberts WW, Stinchcombe JC, Ritter AT, Akhmanova A, Karakesisoglou I, Griffiths GM.

Eur J Immunol. 2012 Aug;42(8):2132-41. doi: 10.1002/eji.201242525.

PMID:
22736282
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Positive and negative signaling through SLAM receptors regulate synapse organization and thresholds of cytolysis.

Zhao F, Cannons JL, Dutta M, Griffiths GM, Schwartzberg PL.

Immunity. 2012 Jun 29;36(6):1003-16. doi: 10.1016/j.immuni.2012.05.017. Epub 2012 Jun 7.

PMID:
22683123
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Centriole polarisation to the immunological synapse directs secretion from cytolytic cells of both the innate and adaptive immune systems.

Stinchcombe JC, Salio M, Cerundolo V, Pende D, Arico M, Griffiths GM.

BMC Biol. 2011 Jun 28;9:45. doi: 10.1186/1741-7007-9-45.

PMID:
21711522
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A role for Rab7 in the movement of secretory granules in cytotoxic T lymphocytes.

Daniele T, Hackmann Y, Ritter AT, Wenham M, Booth S, Bossi G, Schintler M, Auer-Grumbach M, Griffiths GM.

Traffic. 2011 Jul;12(7):902-11. doi: 10.1111/j.1600-0854.2011.01194.x. Epub 2011 Apr 21.

PMID:
21438969
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Centrosome docking at the immunological synapse is controlled by Lck signaling.

Tsun A, Qureshi I, Stinchcombe JC, Jenkins MR, de la Roche M, Kleczkowska J, Zamoyska R, Griffiths GM.

J Cell Biol. 2011 Feb 21;192(4):663-74. doi: 10.1083/jcb.201008140.

PMID:
21339332
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Genotype-phenotype study of familial haemophagocytic lymphohistiocytosis type 3.

Sieni E, Cetica V, Santoro A, Beutel K, Mastrodicasa E, Meeths M, Ciambotti B, Brugnolo F, zur Stadt U, Pende D, Moretta L, Griffiths GM, Henter JI, Janka G, Aricò M.

J Med Genet. 2011 May;48(5):343-52. doi: 10.1136/jmg.2010.085456. Epub 2011 Jan 19.

PMID:
21248318
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

STXBP2 mutations in children with familial haemophagocytic lymphohistiocytosis type 5.

Cetica V, Santoro A, Gilmour KC, Sieni E, Beutel K, Pende D, Marcenaro S, Koch F, Grieve S, Wheeler R, Zhao F, zur Stadt U, Griffiths GM, Aricò M.

J Med Genet. 2010 Sep;47(9):595-600. doi: 10.1136/jmg.2009.075341.

PMID:
20798128
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The immunological synapse: a focal point for endocytosis and exocytosis.

Griffiths GM, Tsun A, Stinchcombe JC.

J Cell Biol. 2010 May 3;189(3):399-406. doi: 10.1083/jcb.201002027. Review.

PMID:
20439993
[PubMed - indexed for MEDLINE]
Free PMC Article
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