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Filtration markers and determination methods for the assessment of kidney function.

Huang J, Gretz N, Weinfurter S.

Eur J Pharmacol. 2016 Jul 1. pii: S0014-2999(16)30429-0. doi: 10.1016/j.ejphar.2016.06.060. [Epub ahead of print]


A Comprehensive Review on the Genetic Regulation of Cisplatin-induced Nephrotoxicity.

Herrera-Pérez Z, Gretz N, Dweep H.

Curr Genomics. 2016 Jun;17(3):279-93. doi: 10.2174/1389202917666160202220555.


Kidney Injury Molecule-1 Is Specifically Expressed in Cystically-Transformed Proximal Tubules of the PKD/Mhm (cy/+) Rat Model of Polycystic Kidney Disease.

Gauer S, Urbschat A, Gretz N, Hoffmann SC, Kränzlin B, Geiger H, Obermüller N.

Int J Mol Sci. 2016 May 24;17(6). pii: E802. doi: 10.3390/ijms17060802.


Transcutaneous Assessment of Renal Function in Conscious Rodents.

Herrera Pérez Z, Weinfurter S, Gretz N.

J Vis Exp. 2016 Mar 26;(109). doi: 10.3791/53767.


Assessing the potential of pharmaceuticals and their transformation products to cause mutagenic effects: Implications for gene expression profiling.

Vasquez MI, Tarapoulouzi M, Lambrianides N, Hapeshi E, Felekkis K, Saile M, Sticht C, Gretz N, Fatta-Kassinos D.

Environ Toxicol Chem. 2016 Apr 4. doi: 10.1002/etc.3444. [Epub ahead of print]


Maternal Glucose Intolerance Reduces Offspring Nephron Endowment and Increases Glomerular Volume in Adult Offspring.

Hokke S, Arias N, Armitage JA, Puelles VG, Fong K, Geraci S, Gretz N, Bertram JF, Cullen-McEwen LA.

Diabetes Metab Res Rev. 2016 Apr 2. doi: 10.1002/dmrr.2805. [Epub ahead of print]


Cellular apoptosis susceptibility (CAS) is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC).

Winkler J, Roessler S, Sticht C, DiGuilio AL, Drucker E, Holzer K, Eiteneuer E, Herpel E, Breuhahn K, Gretz N, Schirmacher P, Ori A, Singer S.

Oncotarget. 2016 Mar 23. doi: 10.18632/oncotarget.8256. [Epub ahead of print]


Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia.

Schäfer M, Oeing CU, Rohm M, Baysal-Temel E, Lehmann LH, Bauer R, Volz HC, Boutros M, Sohn D, Sticht C, Gretz N, Eichelbaum K, Werner T, Hirt MN, Eschenhagen T, Müller-Decker K, Strobel O, Hackert T, Krijgsveld J, Katus HA, Berriel Diaz M, Backs J, Herzig S.

Mol Metab. 2015 Nov 26;5(2):67-78. doi: 10.1016/j.molmet.2015.11.004. eCollection 2016 Feb.


Toxicity study of ochratoxin A using HEK293 and HepG2 cell lines based on microRNA profiling.

Zhao J, Qi X, Dai Q, He X, Dweep H, Guo M, Luo Y, Gretz N, Luo H, Huang K, Xu W.

Hum Exp Toxicol. 2016 Feb 18. pii: 0960327116632048. [Epub ahead of print]


Fast glomerular quantification of whole ex vivo mouse kidneys using Magnetic Resonance Imaging at 9.4 Tesla.

Chacon-Caldera J, Geraci S, Krämer P, Cullen-McEwen L, Bertram JF, Gretz N, Schad LR.

Z Med Phys. 2016 Mar;26(1):54-62. doi: 10.1016/j.zemedi.2015.12.008. Epub 2016 Jan 7.


The renal microenvironment modifies dendritic cell phenotype.

Chessa F, Mathow D, Wang S, Hielscher T, Atzberger A, Porubsky S, Gretz N, Burgdorf S, Gröne HJ, Popovic ZV.

Kidney Int. 2016 Jan;89(1):82-94. doi: 10.1038/ki.2015.292. Epub 2016 Jan 4.


Measures of kidney function by minimally invasive techniques correlate with histological glomerular damage in SCID mice with adriamycin-induced nephropathy.

Scarfe L, Rak-Raszewska A, Geraci S, Darssan D, Sharkey J, Huang J, Burton NC, Mason D, Ranjzad P, Kenny S, Gretz N, Lévy R, Kevin Park B, García-Fiñana M, Woolf AS, Murray P, Wilm B.

Sci Rep. 2015 Sep 2;5:13601. doi: 10.1038/srep13601.


Renal phenotype of young and old telomerase-deficient mice.

Schildhorn C, Jacobi C, Weissbrodt A, Hermstedt C, Westhoff JH, Hömme M, Bhayadia R, Gretz N, Falk CS, Schmitt R, Bröcker V, Kränzlin B, Melk A.

Mech Ageing Dev. 2015 Sep;150:65-73. doi: 10.1016/j.mad.2015.08.004. Epub 2015 Aug 12.


miRWalk2.0: a comprehensive atlas of microRNA-target interactions.

Dweep H, Gretz N.

Nat Methods. 2015 Aug;12(8):697. doi: 10.1038/nmeth.3485. No abstract available.


Alkaline phosphatase protects against renal inflammation through dephosphorylation of lipopolysaccharide and adenosine triphosphate.

Peters E, Geraci S, Heemskerk S, Wilmer MJ, Bilos A, Kraenzlin B, Gretz N, Pickkers P, Masereeuw R.

Br J Pharmacol. 2015 Oct;172(20):4932-45. doi: 10.1111/bph.13261. Epub 2015 Sep 22.


Homo sapiens exhibit a distinct pattern of CNV genes regulation: an important role of miRNAs and SNPs in expression plasticity.

Dweep H, Kubikova N, Gretz N, Voskarides K, Felekkis K.

Sci Rep. 2015 Jul 16;5:12163. doi: 10.1038/srep12163.


Alteration of mRNA and microRNA expression profiles in rat muscular type vasculature in early postnatal development.

Gaynullina D, Dweep H, Gloe T, Tarasova OS, Sticht C, Gretz N, Schubert R.

Sci Rep. 2015 Jun 15;5:11106. doi: 10.1038/srep11106.


Loss of the mechanotransducer zyxin promotes a synthetic phenotype of vascular smooth muscle cells.

Ghosh S, Kollar B, Nahar T, Suresh Babu S, Wojtowicz A, Sticht C, Gretz N, Wagner AH, Korff T, Hecker M.

J Am Heart Assoc. 2015 Jun 12;4(6):e001712. doi: 10.1161/JAHA.114.001712.


Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy.

Stoy C, Sundaram A, Rios Garcia M, Wang X, Seibert O, Zota A, Wendler S, Männle D, Hinz U, Sticht C, Muciek M, Gretz N, Rose AJ, Greiner V, Hofmann TG, Bauer A, Hoheisel J, Berriel Diaz M, Gaida MM, Werner J, Schafmeier T, Strobel O, Herzig S.

EMBO Mol Med. 2015 Jun 12;7(8):1048-62. doi: 10.15252/emmm.201404837.


Nephrotoxicity of ibandronate and zoledronate in Wistar rats with normal renal function and after unilateral nephrectomy.

Bergner R, Siegrist B, Gretz N, Pohlmeyer-Esch G, Kränzlin B.

Pharmacol Res. 2015 Sep;99:16-22. doi: 10.1016/j.phrs.2015.04.016. Epub 2015 May 11.

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