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Results: 18

1.

miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction.

Guda S, Brendel C, Renella R, Du P, Bauer DE, Canver MC, Grenier JK, Grimson AW, Kamran SC, Thornton J, de Boer H, Root DE, Milsom MD, Orkin SH, Gregory RI, Williams DA.

Mol Ther. 2015 Jun 17. doi: 10.1038/mt.2015.113. [Epub ahead of print]

PMID:
26080908
2.

Behavioral idiosyncrasy reveals genetic control of phenotypic variability.

Ayroles JF, Buchanan SM, O'Leary C, Skutt-Kakaria K, Grenier JK, Clark AG, Hartl DL, de Bivort BL.

Proc Natl Acad Sci U S A. 2015 May 26;112(21):6706-11. doi: 10.1073/pnas.1503830112. Epub 2015 May 7.

3.

Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males.

Modzelewski AJ, Hilz S, Crate EA, Schweidenback CT, Fogarty EA, Grenier JK, Freire R, Cohen PE, Grimson A.

J Cell Sci. 2015 Jun 15;128(12):2314-27. doi: 10.1242/jcs.167148. Epub 2015 May 1.

4.

Global diversity lines - a five-continent reference panel of sequenced Drosophila melanogaster strains.

Grenier JK, Arguello JR, Moreira MC, Gottipati S, Mohammed J, Hackett SR, Boughton R, Greenberg AJ, Clark AG.

G3 (Bethesda). 2015 Feb 11;5(4):593-603. doi: 10.1534/g3.114.015883.

5.

Correlated variation and population differentiation in satellite DNA abundance among lines of Drosophila melanogaster.

Wei KH, Grenier JK, Barbash DA, Clark AG.

Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18793-8. doi: 10.1073/pnas.1421951112. Epub 2014 Dec 15.

6.

Receptor tyrosine kinases fall into distinct classes based on their inferred signaling networks.

Wagner JP, Wolf-Yadlin A, Sevecka M, Grenier JK, Root DE, Lauffenburger DA, MacBeath G.

Sci Signal. 2013 Jul 16;6(284):ra58. doi: 10.1126/scisignal.2003994.

7.

lincRNAs act in the circuitry controlling pluripotency and differentiation.

Guttman M, Donaghey J, Carey BW, Garber M, Grenier JK, Munson G, Young G, Lucas AB, Ach R, Bruhn L, Yang X, Amit I, Meissner A, Regev A, Rinn JL, Root DE, Lander ES.

Nature. 2011 Aug 28;477(7364):295-300. doi: 10.1038/nature10398.

8.

A comprehensive platform for highly multiplexed mammalian functional genetic screens.

Ketela T, Heisler LE, Brown KR, Ammar R, Kasimer D, Surendra A, Ericson E, Blakely K, Karamboulas D, Smith AM, Durbic T, Arnoldo A, Cheung-Ong K, Koh JL, Gopal S, Cowley GS, Yang X, Grenier JK, Giaever G, Root DE, Moffat J, Nislow C.

BMC Genomics. 2011 May 6;12:213. doi: 10.1186/1471-2164-12-213.

9.

Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses.

Amit I, Garber M, Chevrier N, Leite AP, Donner Y, Eisenhaure T, Guttman M, Grenier JK, Li W, Zuk O, Schubert LA, Birditt B, Shay T, Goren A, Zhang X, Smith Z, Deering R, McDonald RC, Cabili M, Bernstein BE, Rinn JL, Meissner A, Root DE, Hacohen N, Regev A.

Science. 2009 Oct 9;326(5950):257-63. doi: 10.1126/science.1179050. Epub 2009 Sep 3.

10.

Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning.

Jones TR, Carpenter AE, Lamprecht MR, Moffat J, Silver SJ, Grenier JK, Castoreno AB, Eggert US, Root DE, Golland P, Sabatini DM.

Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1826-31. doi: 10.1073/pnas.0808843106. Epub 2009 Feb 2.

11.

Integrative genomic approaches identify IKBKE as a breast cancer oncogene.

Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, Hirozane-Kishikawa T, Hill DE, Vidal M, Meyerson M, Grenier JK, Hinkle G, Root DE, Roberts TM, Lander ES, Polyak K, Hahn WC.

Cell. 2007 Jun 15;129(6):1065-79.

12.

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen.

Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G, Piqani B, Eisenhaure TM, Luo B, Grenier JK, Carpenter AE, Foo SY, Stewart SA, Stockwell BR, Hacohen N, Hahn WC, Lander ES, Sabatini DM, Root DE.

Cell. 2006 Mar 24;124(6):1283-98.

13.

Exploiting the enzymatic recognition of an unnatural base pair to develop a universal genetic analysis system.

Moser MJ, Marshall DJ, Grenier JK, Kieffer CD, Killeen AA, Ptacin JL, Richmond CS, Roesch EB, Scherrer CW, Sherrill CB, Van Hout CV, Zanton SJ, Prudent JR.

Clin Chem. 2003 Mar;49(3):407-14.

14.

Functional evolution of the Ultrabithorax protein.

Grenier JK, Carroll SB.

Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):704-9.

15.

Hox genes in brachiopods and priapulids and protostome evolution.

de Rosa R, Grenier JK, Andreeva T, Cook CE, Adoutte A, Akam M, Carroll SB, Balavoine G.

Nature. 1999 Jun 24;399(6738):772-6.

PMID:
10391241
16.

Evolution of the entire arthropod Hox gene set predated the origin and radiation of the onychophoran/arthropod clade.

Grenier JK, Garber TL, Warren R, Whitington PM, Carroll S.

Curr Biol. 1997 Aug 1;7(8):547-53.

17.

The origin and evolution of animal appendages.

Panganiban G, Irvine SM, Lowe C, Roehl H, Corley LS, Sherbon B, Grenier JK, Fallon JF, Kimble J, Walker M, Wray GA, Swalla BJ, Martindale MQ, Carroll SB.

Proc Natl Acad Sci U S A. 1997 May 13;94(10):5162-6.

18.
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