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Results: 1 to 20 of 52

1.

Mosaic epigenetic dysregulation of ectodermal cells in autism spectrum disorder.

Berko ER, Suzuki M, Beren F, Lemetre C, Alaimo CM, Calder RB, Ballaban-Gil K, Gounder B, Kampf K, Kirschen J, Maqbool SB, Momin Z, Reynolds DM, Russo N, Shulman L, Stasiek E, Tozour J, Valicenti-McDermott M, Wang S, Abrahams BS, Hargitai J, Inbar D, Zhang Z, Buxbaum JD, Molholm S, Foxe JJ, Marion RW, Auton A, Greally JM.

PLoS Genet. 2014 May 29;10(5):e1004402. doi: 10.1371/journal.pgen.1004402. eCollection 2014.

PMID:
24875834
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

HSC commitment-associated epigenetic signature is prognostic in acute myeloid leukemia.

Bartholdy B, Christopeit M, Will B, Mo Y, Barreyro L, Yu Y, Bhagat TD, Okoye-Okafor UC, Todorova TI, Greally JM, Levine RL, Melnick A, Verma A, Steidl U.

J Clin Invest. 2014 Mar 3;124(3):1158-67.

PMID:
24487588
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Genetic recombination is targeted towards gene promoter regions in dogs.

Auton A, Rui Li Y, Kidd J, Oliveira K, Nadel J, Holloway JK, Hayward JJ, Cohen PE, Greally JM, Wang J, Bustamante CD, Boyko AR.

PLoS Genet. 2013;9(12):e1003984. doi: 10.1371/journal.pgen.1003984. Epub 2013 Dec 12.

PMID:
24348265
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development.

Ko YA, Mohtat D, Suzuki M, Park AS, Izquierdo MC, Han SY, Kang HM, Si H, Hostetter T, Pullman JM, Fazzari M, Verma A, Zheng D, Greally JM, Susztak K.

Genome Biol. 2013;14(10):R108.

PMID:
24098934
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Astrogenomics: big data, old problems, old solutions?

Golden A, Djorgovski S, Greally JM.

Genome Biol. 2013 Aug 13;14(8):129. doi: 10.1186/gb-2013-14-8-129. No abstract available.

PMID:
23953643
[PubMed - in process]
Free PMC Article
6.

Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.

Bhattacharyya S, Yu Y, Suzuki M, Campbell N, Mazdo J, Vasanthakumar A, Bhagat TD, Nischal S, Christopeit M, Parekh S, Steidl U, Godley L, Maitra A, Greally JM, Verma A.

Nucleic Acids Res. 2013 Sep;41(16):e157. doi: 10.1093/nar/gkt601. Epub 2013 Jul 16.

PMID:
23861445
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Large, male germ cell-specific hypomethylated DNA domains with unique genomic and epigenomic features on the mouse X chromosome.

Ikeda R, Shiura H, Numata K, Sugimoto M, Kondo M, Mise N, Suzuki M, Greally JM, Abe K.

DNA Res. 2013 Dec;20(6):549-65. doi: 10.1093/dnares/dst030. Epub 2013 Jul 15.

PMID:
23861320
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Differential epigenome-wide DNA methylation patterns in childhood obesity-associated asthma.

Rastogi D, Suzuki M, Greally JM.

Sci Rep. 2013;3:2164. doi: 10.1038/srep02164.

PMID:
23857381
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes.

Gendrel AV, Tang YA, Suzuki M, Godwin J, Nesterova TB, Greally JM, Heard E, Brockdorff N.

Mol Cell Biol. 2013 Aug;33(16):3150-65. doi: 10.1128/MCB.00145-13. Epub 2013 Jun 10.

PMID:
23754746
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes.

Reddington JP, Perricone SM, Nestor CE, Reichmann J, Youngson NA, Suzuki M, Reinhardt D, Dunican DS, Prendergast JG, Mjoseng H, Ramsahoye BH, Whitelaw E, Greally JM, Adams IR, Bickmore WA, Meehan RR.

Genome Biol. 2013 Mar 25;14(3):R25. doi: 10.1186/gb-2013-14-3-r25.

PMID:
23531360
[PubMed - in process]
Free PMC Article
11.

Bidding the CpG island goodbye.

Greally JM.

Elife. 2013 Feb 26;2:e00593. doi: 10.7554/eLife.00593.

PMID:
23467495
[PubMed - in process]
Free PMC Article
12.

Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica.

Das R, Anderson N, Koran MI, Weidman JR, Mikkelsen TS, Kamal M, Murphy SK, Linblad-Toh K, Greally JM, Jirtle RL.

BMC Genomics. 2012 Aug 16;13:394. doi: 10.1186/1471-2164-13-394.

PMID:
22899817
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations.

Will B, Zhou L, Vogler TO, Ben-Neriah S, Schinke C, Tamari R, Yu Y, Bhagat TD, Bhattacharyya S, Barreyro L, Heuck C, Mo Y, Parekh S, McMahon C, Pellagatti A, Boultwood J, Montagna C, Silverman L, Maciejewski J, Greally JM, Ye BH, List AF, Steidl C, Steidl U, Verma A.

Blood. 2012 Sep 6;120(10):2076-86. doi: 10.1182/blood-2011-12-399683. Epub 2012 Jul 2.

PMID:
22753872
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Phase II trial of the histone deacetylase inhibitor romidepsin in patients with recurrent/metastatic head and neck cancer.

Haigentz M Jr, Kim M, Sarta C, Lin J, Keresztes RS, Culliney B, Gaba AG, Smith RV, Shapiro GI, Chirieac LR, Mariadason JM, Belbin TJ, Greally JM, Wright JJ, Haddad RI.

Oral Oncol. 2012 Dec;48(12):1281-8. doi: 10.1016/j.oraloncology.2012.05.024. Epub 2012 Jun 28.

PMID:
22748449
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Epigenetic silencing of the circadian clock gene CRY1 is associated with an indolent clinical course in chronic lymphocytic leukemia.

Hanoun M, Eisele L, Suzuki M, Greally JM, Hüttmann A, Aydin S, Scholtysik R, Klein-Hitpass L, Dührsen U, Dürig J.

PLoS One. 2012;7(3):e34347. doi: 10.1371/journal.pone.0034347. Epub 2012 Mar 28.

PMID:
22470559
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Repressor element-1 silencing transcription factor (REST)-dependent epigenetic remodeling is critical to ischemia-induced neuronal death.

Noh KM, Hwang JY, Follenzi A, Athanasiadou R, Miyawaki T, Greally JM, Bennett MV, Zukin RS.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):E962-71. doi: 10.1073/pnas.1121568109. Epub 2012 Feb 27.

PMID:
22371606
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Late-replicating heterochromatin is characterized by decreased cytosine methylation in the human genome.

Suzuki M, Oda M, Ramos MP, Pascual M, Lau K, Stasiek E, Agyiri F, Thompson RF, Glass JL, Jing Q, Sandstrom R, Fazzari MJ, Hansen RS, Stamatoyannopoulos JA, McLellan AS, Greally JM.

Genome Res. 2011 Nov;21(11):1833-40. doi: 10.1101/gr.116509.110. Epub 2011 Sep 28.

PMID:
21957152
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Allele-specific transcriptional elongation regulates monoallelic expression of the IGF2BP1 gene.

Thomas BJ, Rubio ED, Krumm N, Broin PO, Bomsztyk K, Welcsh P, Greally JM, Golden AA, Krumm A.

Epigenetics Chromatin. 2011 Aug 3;4:14. doi: 10.1186/1756-8935-4-14.

PMID:
21812971
[PubMed]
Free PMC Article
19.

Aberrant epigenetic and genetic marks are seen in myelodysplastic leukocytes and reveal Dock4 as a candidate pathogenic gene on chromosome 7q.

Zhou L, Opalinska J, Sohal D, Yu Y, Mo Y, Bhagat T, Abdel-Wahab O, Fazzari M, Figueroa M, Alencar C, Zhang J, Kambhampati S, Parmar S, Nischal S, Hueck C, Suzuki M, Freidman E, Pellagatti A, Boultwood J, Steidl U, Sauthararajah Y, Yajnik V, McMahon C, Gore SD, Platanias LC, Levine R, Melnick A, Wickrema A, Greally JM, Verma A.

J Biol Chem. 2011 Jul 15;286(28):25211-23. doi: 10.1074/jbc.M111.235028. Epub 2011 Apr 30.

PMID:
21532034
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis.

Alvarez H, Opalinska J, Zhou L, Sohal D, Fazzari MJ, Yu Y, Montagna C, Montgomery EA, Canto M, Dunbar KB, Wang J, Roa JC, Mo Y, Bhagat T, Ramesh KH, Cannizzaro L, Mollenhauer J, Thompson RF, Suzuki M, Meltzer SJ, Melnick A, Greally JM, Maitra A, Verma A.

PLoS Genet. 2011 Mar;7(3):e1001356. doi: 10.1371/journal.pgen.1001356. Epub 2011 Mar 31. Erratum in: PLoS Genet. 2011 May;7(5). doi: 10.1371/annotation/8dcded85-a924-40f4-a7ea-56961b87447f. Meltzer, Stephen [corrected to Meltzer, Stephen J].

PMID:
21483804
[PubMed - indexed for MEDLINE]
Free PMC Article
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