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Results: 1 to 20 of 61

1.

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.

Wong TN, Ramsingh G, Young AL, Miller CA, Touma W, Welch JS, Lamprecht TL, Shen D, Hundal J, Fulton RS, Heath S, Baty JD, Klco JM, Ding L, Mardis ER, Westervelt P, DiPersio JF, Walter MJ, Graubert TA, Ley TJ, Druley TE, Link DC, Wilson RK.

Nature. 2014 Dec 8. doi: 10.1038/nature13968. [Epub ahead of print]

PMID:
25487151
[PubMed - as supplied by publisher]
2.

Quality of life and mood of patients and family caregivers during hospitalization for hematopoietic stem cell transplantation.

El-Jawahri AR, Traeger LN, Kuzmuk K, Eusebio JR, Vandusen HB, Shin JA, Keenan T, Gallagher ER, Greer JA, Pirl WF, Jackson VA, Ballen KK, Spitzer TR, Graubert TA, McAfee SL, Dey BR, Chen YB, Temel JS.

Cancer. 2014 Dec 2. doi: 10.1002/cncr.29149. [Epub ahead of print]

PMID:
25469752
[PubMed - as supplied by publisher]
3.

Caspase 9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice.

Lu EP, McLellan M, Ding L, Fulton R, Mardis ER, Wilson RK, Miller C, Westervelt P, DiPersio JF, Link DC, Walter MJ, Ley TJ, Graubert TA.

Blood. 2014 Oct 27. pii: blood-2014-06-582551. [Epub ahead of print]

PMID:
25349173
[PubMed - as supplied by publisher]
4.

U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing.

Okeyo-Owuor T, White BS, Chatrikhi R, Mohan DR, Kim S, Griffith M, Ding L, Ketkar-Kulkarni S, Hundal J, Laird KM, Kielkopf CL, Ley TJ, Walter MJ, Graubert TA.

Leukemia. 2014 Oct 14. doi: 10.1038/leu.2014.303. [Epub ahead of print]

PMID:
25311244
[PubMed - as supplied by publisher]
5.

A call to action for acute lymphoblastic leukemia.

Graubert TA.

N Engl J Med. 2014 Sep 11;371(11):1064-6. doi: 10.1056/NEJMe1407477. No abstract available.

PMID:
25207770
[PubMed - indexed for MEDLINE]
6.

SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution.

Miller CA, White BS, Dees ND, Griffith M, Welch JS, Griffith OL, Vij R, Tomasson MH, Graubert TA, Walter MJ, Ellis MJ, Schierding W, DiPersio JF, Ley TJ, Mardis ER, Wilson RK, Ding L.

PLoS Comput Biol. 2014 Aug 7;10(8):e1003665. doi: 10.1371/journal.pcbi.1003665. eCollection 2014 Aug.

PMID:
25102416
[PubMed - in process]
Free PMC Article
7.

Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results.

Tabor HK, Auer PL, Jamal SM, Chong JX, Yu JH, Gordon AS, Graubert TA, O'Donnell CJ, Rich SS, Nickerson DA; NHLBI Exome Sequencing Project, Bamshad MJ.

Am J Hum Genet. 2014 Aug 7;95(2):183-93. doi: 10.1016/j.ajhg.2014.07.006. Epub 2014 Jul 31.

PMID:
25087612
[PubMed - indexed for MEDLINE]
8.

Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing.

Hughes AE, Magrini V, Demeter R, Miller CA, Fulton R, Fulton LL, Eades WC, Elliott K, Heath S, Westervelt P, Ding L, Conrad DF, White BS, Shao J, Link DC, DiPersio JF, Mardis ER, Wilson RK, Ley TJ, Walter MJ, Graubert TA.

PLoS Genet. 2014 Jul 10;10(7):e1004462. doi: 10.1371/journal.pgen.1004462. eCollection 2014 Jul.

PMID:
25010716
[PubMed - in process]
Free PMC Article
9.

New molecular abnormalities and clonal architecture in AML: from reciprocal translocations to whole-genome sequencing.

Graubert TA, Brunner AM, Fathi AT.

Am Soc Clin Oncol Educ Book. 2014:e334-40. doi: 10.14694/EdBook_AM.2014.34.e334.

PMID:
24857122
[PubMed - in process]
Free Article
10.

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia.

Klco JM, Spencer DH, Miller CA, Griffith M, Lamprecht TL, O'Laughlin M, Fronick C, Magrini V, Demeter RT, Fulton RS, Eades WC, Link DC, Graubert TA, Walter MJ, Mardis ER, Dipersio JF, Wilson RK, Ley TJ.

Cancer Cell. 2014 Mar 17;25(3):379-92. doi: 10.1016/j.ccr.2014.01.031. Epub 2014 Mar 6.

PMID:
24613412
[PubMed - indexed for MEDLINE]
11.

Integrated analysis of germline and somatic variants in ovarian cancer.

Kanchi KL, Johnson KJ, Lu C, McLellan MD, Leiserson MD, Wendl MC, Zhang Q, Koboldt DC, Xie M, Kandoth C, McMichael JF, Wyczalkowski MA, Larson DE, Schmidt HK, Miller CA, Fulton RS, Spellman PT, Mardis ER, Druley TE, Graubert TA, Goodfellow PJ, Raphael BJ, Wilson RK, Ding L.

Nat Commun. 2014;5:3156. doi: 10.1038/ncomms4156.

PMID:
24448499
[PubMed - in process]
Free PMC Article
12.

SWR/J mice are susceptible to alkylator-induced myeloid leukemia.

Janke MR, Baty JD, Graubert TA.

Blood Cancer J. 2013 Nov 15;3:e161. doi: 10.1038/bcj.2013.59. No abstract available.

PMID:
24241401
[PubMed]
Free PMC Article
13.

Clonal diversity of recurrently mutated genes in myelodysplastic syndromes.

Walter MJ, Shen D, Shao J, Ding L, White BS, Kandoth C, Miller CA, Niu B, McLellan MD, Dees ND, Fulton R, Elliot K, Heath S, Grillot M, Westervelt P, Link DC, DiPersio JF, Mardis E, Ley TJ, Wilson RK, Graubert TA.

Leukemia. 2013 Jun;27(6):1275-82. doi: 10.1038/leu.2013.58. Epub 2013 Feb 27.

PMID:
23443460
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project.

Auer PL, Johnsen JM, Johnson AD, Logsdon BA, Lange LA, Nalls MA, Zhang G, Franceschini N, Fox K, Lange EM, Rich SS, O'Donnell CJ, Jackson RD, Wallace RB, Chen Z, Graubert TA, Wilson JG, Tang H, Lettre G, Reiner AP, Ganesh SK, Li Y.

Am J Hum Genet. 2012 Nov 2;91(5):794-808. doi: 10.1016/j.ajhg.2012.08.031. Epub 2012 Oct 25.

PMID:
23103231
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The origin and evolution of mutations in acute myeloid leukemia.

Welch JS, Ley TJ, Link DC, Miller CA, Larson DE, Koboldt DC, Wartman LD, Lamprecht TL, Liu F, Xia J, Kandoth C, Fulton RS, McLellan MD, Dooling DJ, Wallis JW, Chen K, Harris CC, Schmidt HK, Kalicki-Veizer JM, Lu C, Zhang Q, Lin L, O'Laughlin MD, McMichael JF, Delehaunty KD, Fulton LA, Magrini VJ, McGrath SD, Demeter RT, Vickery TL, Hundal J, Cook LL, Swift GW, Reed JP, Alldredge PA, Wylie TN, Walker JR, Watson MA, Heath SE, Shannon WD, Varghese N, Nagarajan R, Payton JE, Baty JD, Kulkarni S, Klco JM, Tomasson MH, Westervelt P, Walter MJ, Graubert TA, DiPersio JF, Ding L, Mardis ER, Wilson RK.

Cell. 2012 Jul 20;150(2):264-78. doi: 10.1016/j.cell.2012.06.023.

PMID:
22817890
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Clonal architecture of secondary acute myeloid leukemia.

Walter MJ, Shen D, Ding L, Shao J, Koboldt DC, Chen K, Larson DE, McLellan MD, Dooling D, Abbott R, Fulton R, Magrini V, Schmidt H, Kalicki-Veizer J, O'Laughlin M, Fan X, Grillot M, Witowski S, Heath S, Frater JL, Eades W, Tomasson M, Westervelt P, DiPersio JF, Link DC, Mardis ER, Ley TJ, Wilson RK, Graubert TA.

N Engl J Med. 2012 Mar 22;366(12):1090-8. doi: 10.1056/NEJMoa1106968. Epub 2012 Mar 14.

PMID:
22417201
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing.

Ding L, Ley TJ, Larson DE, Miller CA, Koboldt DC, Welch JS, Ritchey JK, Young MA, Lamprecht T, McLellan MD, McMichael JF, Wallis JW, Lu C, Shen D, Harris CC, Dooling DJ, Fulton RS, Fulton LL, Chen K, Schmidt H, Kalicki-Veizer J, Magrini VJ, Cook L, McGrath SD, Vickery TL, Wendl MC, Heath S, Watson MA, Link DC, Tomasson MH, Shannon WD, Payton JE, Kulkarni S, Westervelt P, Walter MJ, Graubert TA, Mardis ER, Wilson RK, DiPersio JF.

Nature. 2012 Jan 11;481(7382):506-10. doi: 10.1038/nature10738.

PMID:
22237025
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes.

Graubert TA, Shen D, Ding L, Okeyo-Owuor T, Lunn CL, Shao J, Krysiak K, Harris CC, Koboldt DC, Larson DE, McLellan MD, Dooling DJ, Abbott RM, Fulton RS, Schmidt H, Kalicki-Veizer J, O'Laughlin M, Grillot M, Baty J, Heath S, Frater JL, Nasim T, Link DC, Tomasson MH, Westervelt P, DiPersio JF, Mardis ER, Ley TJ, Wilson RK, Walter MJ.

Nat Genet. 2011 Dec 11;44(1):53-7. doi: 10.1038/ng.1031.

PMID:
22158538
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Genomics of acute myeloid leukemia.

Graubert TA, Mardis ER.

Cancer J. 2011 Nov-Dec;17(6):487-91. doi: 10.1097/PPO.0b013e31823c5652. Review.

PMID:
22157292
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Use of whole-genome sequencing to diagnose a cryptic fusion oncogene.

Welch JS, Westervelt P, Ding L, Larson DE, Klco JM, Kulkarni S, Wallis J, Chen K, Payton JE, Fulton RS, Veizer J, Schmidt H, Vickery TL, Heath S, Watson MA, Tomasson MH, Link DC, Graubert TA, DiPersio JF, Mardis ER, Ley TJ, Wilson RK.

JAMA. 2011 Apr 20;305(15):1577-84. doi: 10.1001/jama.2011.497.

PMID:
21505136
[PubMed - indexed for MEDLINE]
Free PMC Article
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