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A Phase I Study of the SMAC-Mimetic Birinapant in Adults with Refractory Solid Tumors or Lymphoma.

Amaravadi RK, Schilder RJ, Martin LP, Levin M, Graham MA, Weng DE, Adjei AA.

Mol Cancer Ther. 2015 Nov;14(11):2569-75. doi: 10.1158/1535-7163.MCT-15-0475. Epub 2015 Sep 2.


Iterative development and the scope for plasticity: contrasts among trait categories in an adaptive radiation.

Foster SA, Wund MA, Graham MA, Earley RL, Gardiner R, Kearns T, Baker JA.

Heredity (Edinb). 2015 Oct;115(4):335-48. doi: 10.1038/hdy.2015.66. Epub 2015 Aug 5. Review.


The Medicago sativa gene index 1.2: a web-accessible gene expression atlas for investigating expression differences between Medicago sativa subspecies.

O'Rourke JA, Fu F, Bucciarelli B, Yang SS, Samac DA, Lamb JF, Monteros MJ, Graham MA, Gronwald JW, Krom N, Li J, Dai X, Zhao PX, Vance CP.

BMC Genomics. 2015 Jul 7;16:502. doi: 10.1186/s12864-015-1718-7.


Structure-Guided Design of Highly Selective and Potent Covalent Inhibitors of ERK1/2.

Ward RA, Colclough N, Challinor M, Debreczeni JE, Eckersley K, Fairley G, Feron L, Flemington V, Graham MA, Greenwood R, Hopcroft P, Howard TD, James M, Jones CD, Jones CR, Renshaw J, Roberts K, Snow L, Tonge M, Yeung K.

J Med Chem. 2015 Jun 11;58(11):4790-801. doi: 10.1021/acs.jmedchem.5b00466. Epub 2015 May 28.


Gaining insight into soybean defense responses using functional genomics approaches.

Liu JZ, Graham MA, Pedley KF, Whitham SA.

Brief Funct Genomics. 2015 Jul;14(4):283-90. doi: 10.1093/bfgp/elv009. Epub 2015 Mar 31. Review.


Environmental Justice and Community-Based Research in Texas Borderland Colonias.

Cantu A, Graham MA, Millard AV, Flores I, Mugleston MK, Reyes IY, Carbajal ES.

Public Health Nurs. 2015 Mar 18. doi: 10.1111/phn.12187. [Epub ahead of print]


Discovery and optimization of a novel series of Dyrk1B kinase inhibitors to explore a MEK resistance hypothesis.

Kettle JG, Ballard P, Bardelle C, Cockerill M, Colclough N, Critchlow SE, Debreczeni J, Fairley G, Fillery S, Graham MA, Goodwin L, Guichard S, Hudson K, Ward RA, Whittaker D.

J Med Chem. 2015 Mar 26;58(6):2834-44. doi: 10.1021/acs.jmedchem.5b00098. Epub 2015 Mar 12.


Synthesis of functionalized cyanopyrazoles via magnesium bases.

Dishington A, Feron JL, Gill K, Graham MA, Hollingsworth I, Pink JH, Roberts A, Simpson I, Tatton M.

Org Lett. 2014 Dec 5;16(23):6120-3. doi: 10.1021/ol502977a. Epub 2014 Nov 13.


Comprehensive characterization and RNA-Seq profiling of the HD-Zip transcription factor family in soybean (Glycine max) during dehydration and salt stress.

Belamkar V, Weeks NT, Bharti AK, Farmer AD, Graham MA, Cannon SB.

BMC Genomics. 2014 Nov 3;15:950. doi: 10.1186/1471-2164-15-950.


Identification of candidate genes involved in early iron deficiency chlorosis signaling in soybean (Glycine max) roots and leaves.

Moran Lauter AN, Peiffer GA, Yin T, Whitham SA, Cook D, Shoemaker RC, Graham MA.

BMC Genomics. 2014 Aug 22;15:702. doi: 10.1186/1471-2164-15-702.


Birinapant, a smac-mimetic with improved tolerability for the treatment of solid tumors and hematological malignancies.

Condon SM, Mitsuuchi Y, Deng Y, LaPorte MG, Rippin SR, Haimowitz T, Alexander MD, Kumar PT, Hendi MS, Lee YH, Benetatos CA, Yu G, Kapoor GS, Neiman E, Seipel ME, Burns JM, Graham MA, McKinlay MA, Li X, Wang J, Shi Y, Feltham R, Bettjeman B, Cumming MH, Vince JE, Khan N, Silke J, Day CL, Chunduru SK.

J Med Chem. 2014 May 8;57(9):3666-77. doi: 10.1021/jm500176w. Epub 2014 Apr 15.


Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-associated cIAPs, abrogates TNF-induced NF-κB activation, and is active in patient-derived xenograft models.

Benetatos CA, Mitsuuchi Y, Burns JM, Neiman EM, Condon SM, Yu G, Seipel ME, Kapoor GS, Laporte MG, Rippin SR, Deng Y, Hendi MS, Tirunahari PK, Lee YH, Haimowitz T, Alexander MD, Graham MA, Weng D, Shi Y, McKinlay MA, Chunduru SK.

Mol Cancer Ther. 2014 Apr;13(4):867-79. doi: 10.1158/1535-7163.MCT-13-0798. Epub 2014 Feb 21. Erratum in: Mol Cancer Ther. 2014 Sep;13(9):2246-7. Dosage error in article text.


The haustorial transcriptomes of Uromyces appendiculatus and Phakopsora pachyrhizi and their candidate effector families.

Link TI, Lang P, Scheffler BE, Duke MV, Graham MA, Cooper B, Tucker ML, van de Mortel M, Voegele RT, Mendgen K, Baum TJ, Whitham SA.

Mol Plant Pathol. 2014 May;15(4):379-93. doi: 10.1111/mpp.12099. Epub 2013 Dec 17.


Novel and versatile synthesis of disubstituted 1,2-dihydro-1,2,4-triazol-3-ones.

Graham MA, Bethel PA, Burgess J, Fairley G, Glossop SC, Greenwood RD, Jones CD, Lovell S, Swallow S.

Org Lett. 2013 Dec 6;15(23):6078-81. doi: 10.1021/ol402920z. Epub 2013 Nov 18.


A re-sequencing based assessment of genomic heterogeneity and fast neutron-induced deletions in a common bean cultivar.

O'Rourke JA, Iniguez LP, Bucciarelli B, Roessler J, Schmutz J, McClean PE, Jackson SA, Hernandez G, Graham MA, Stupar RM, Vance CP.

Front Plant Sci. 2013 Jun 25;4:210. doi: 10.3389/fpls.2013.00210. eCollection 2013.


Replication protein A subunit 3 and the iron efficiency response in soybean.

Atwood SE, O'Rourke JA, Peiffer GA, Yin T, Majumder M, Zhang C, Cianzio SR, Hill JH, Cook D, Whitham SA, Shoemaker RC, Graham MA.

Plant Cell Environ. 2014 Jan;37(1):213-34. doi: 10.1111/pce.12147. Epub 2013 Jul 22.


Temporal and spatial evolution of therapy-induced tumor apoptosis detected by caspase-3-selective molecular imaging.

Nguyen QD, Lavdas I, Gubbins J, Smith G, Fortt R, Carroll LS, Graham MA, Aboagye EO.

Clin Cancer Res. 2013 Jul 15;19(14):3914-24. doi: 10.1158/1078-0432.CCR-12-3814. Epub 2013 May 31.


The stability of electrically induced ventricular fibrillation.

Kroll MW, Walcott GP, Ideker RE, Graham MA, Calkins H, Lakkireddy D, Luceri RM, Panescu D.

Conf Proc IEEE Eng Med Biol Soc. 2012;2012:6377-81. doi: 10.1109/EMBC.2012.6347453.


Sulfonyl-morpholino-pyrimidines: SAR and development of a novel class of selective mTOR kinase inhibitor.

Finlay MR, Buttar D, Critchlow SE, Dishington AP, Fillery SM, Fisher E, Glossop SC, Graham MA, Johnson T, Lamont GM, Mutton S, Perkins P, Pike KG, Slater AM.

Bioorg Med Chem Lett. 2012 Jun 15;22(12):4163-8. doi: 10.1016/j.bmcl.2012.04.036. Epub 2012 Apr 13.


An overview of nonpathological geroneuropsychology: implications for nursing practice and research.

Vance DE, Graham MA, Fazeli PL, Heaton K, Moneyham L.

J Neurosci Nurs. 2012 Feb;44(1):43-53. doi: 10.1097/JNN.0b013e31823ae48b. Review.

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