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A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells.

Hvichia GE, Parveen Z, Wagner C, Janning M, Quidde J, Stein A, Müller V, Loges S, Neves RP, Stoecklein NH, Wikman H, Riethdorf S, Pantel K, Gorges TM.

Int J Cancer. 2016 Jun 15;138(12):2894-904. doi: 10.1002/ijc.30007. Epub 2016 Feb 26.


Enumeration and Molecular Characterization of Tumor Cells in Lung Cancer Patients Using a Novel In Vivo Device for Capturing Circulating Tumor Cells.

Gorges TM, Penkalla N, Schalk T, Joosse SA, Riethdorf S, Tucholski J, Lücke K, Wikman H, Jackson S, Brychta N, von Ahsen O, Schumann C, Krahn T, Pantel K.

Clin Cancer Res. 2015 Dec 14. [Epub ahead of print]


Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response.

Bartkowiak K, Kwiatkowski M, Buck F, Gorges TM, Nilse L, Assmann V, Andreas A, Müller V, Wikman H, Riethdorf S, Schlüter H, Pantel K.

Cancer Res. 2015 Dec 15;75(24):5367-77. doi: 10.1158/0008-5472.CAN-14-3728. Epub 2015 Nov 16.


A Versatile Microarray Platform for Capturing Rare Cells.

Brinkmann F, Hirtz M, Haller A, Gorges TM, Vellekoop MJ, Riethdorf S, Müller V, Pantel K, Fuchs H.

Sci Rep. 2015 Oct 23;5:15342. doi: 10.1038/srep15342.


Circulating tumour cell-derived plastin3 is a novel marker for predicting long-term prognosis in patients with breast cancer.

Ueo H, Sugimachi K, Gorges TM, Bartkowiak K, Yokobori T, Müller V, Shinden Y, Ueda M, Ueo H, Mori M, Kuwano H, Maehara Y, Ohno S, Pantel K, Mimori K.

Br J Cancer. 2015 Apr 28;112(9):1519-26. doi: 10.1038/bjc.2015.132. Epub 2015 Apr 16.


Biology, detection, and clinical implications of circulating tumor cells.

Joosse SA, Gorges TM, Pantel K.

EMBO Mol Med. 2014 Nov 14;7(1):1-11. doi: 10.15252/emmm.201303698. Review.


Circulating tumor cells as therapy-related biomarkers in cancer patients.

Gorges TM, Pantel K.

Cancer Immunol Immunother. 2013 May;62(5):931-9. doi: 10.1007/s00262-012-1387-1. Epub 2013 Jan 12. Review.


Cancer therapy monitoring in xenografts by quantitative analysis of circulating tumor DNA.

Gorges TM, Schiller J, Schmitz A, Schuetzmann D, Schatz C, Zollner TM, Krahn T, von Ahsen O.

Biomarkers. 2012 Sep;17(6):498-506. doi: 10.3109/1354750X.2012.689133. Epub 2012 May 23.


Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition.

Gorges TM, Tinhofer I, Drosch M, Röse L, Zollner TM, Krahn T, von Ahsen O.

BMC Cancer. 2012 May 16;12:178. doi: 10.1186/1471-2407-12-178.

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