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Results: 1 to 20 of 146

1.

Scorpion venoms as a potential source of novel cancer therapeutic compounds.

Ding J, Chua PJ, Bay BH, Gopalakrishnakone P.

Exp Biol Med (Maywood). 2014 Apr;239(4):387-93. doi: 10.1177/1535370213513991. Epub 2014 Mar 5. Review.

PMID:
24599885
2.

Wound healing activity and mechanisms of action of an antibacterial protein from the venom of the eastern diamondback rattlesnake (Crotalus adamanteus).

Samy RP, Kandasamy M, Gopalakrishnakone P, Stiles BG, Rowan EG, Becker D, Shanmugam MK, Sethi G, Chow VT.

PLoS One. 2014 Feb 14;9(2):e80199. doi: 10.1371/journal.pone.0080199. eCollection 2014.

3.

Cross-Reactivity against Naja sumatrana (Black Spitting Cobra) Envenoming from the Haffkine Antivenom in a Mouse Model.

Cham G, Lim F, Earnest A, Gopalakrishnakone P.

ISRN Toxicol. 2013 Aug 12;2013:247645. doi: 10.1155/2013/247645. eCollection 2013.

4.

Synthesis and characterization of amino acid deletion analogs of κ-hefutoxin 1, a scorpion toxin on potassium channels.

Peigneur S, Yamaguchi Y, Goto H, Srinivasan KN, Gopalakrishnakone P, Tytgat J, Sato K.

Toxicon. 2013 Sep;71:25-30. doi: 10.1016/j.toxicon.2013.05.010. Epub 2013 May 29.

PMID:
23726856
5.

Apoptogenic activity of ethyl acetate extract of leaves of Memecylon edule on human gastric carcinoma cells via mitochondrial dependent pathway.

Naidu VG, Mahesh BU, Giddam AK, Babu KR, Ding J, babu KS, Ramesh B, Pragada RR, Gopalakrishnakone P.

Asian Pac J Trop Med. 2013 May 13;6(5):337-45. doi: 10.1016/S1995-7645(13)60036-X.

6.

RANKL targeted peptides inhibit osteoclastogenesis and attenuate adjuvant induced arthritis by inhibiting NF-κB activation and down regulating inflammatory cytokines.

Naidu VG, Dinesh Babu KR, Thwin MM, Satish RL, Kumar PV, Gopalakrishnakone P.

Chem Biol Interact. 2013 Apr 25;203(2):467-79. doi: 10.1016/j.cbi.2012.12.016. Epub 2013 Jan 17.

PMID:
23333834
7.

Snake venom phospholipases A(2): a novel tool against bacterial diseases.

Samy RP, Gopalakrishnakone P, Stiles BG, Girish KS, Swamy SN, Hemshekhar M, Tan KS, Rowan EG, Sethi G, Chow VT.

Curr Med Chem. 2012;19(36):6150-62. Review.

PMID:
22963667
8.

Therapeutic application of natural inhibitors against snake venom phospholipase A(2).

Perumal Samy R, Gopalakrishnakone P, Chow VT.

Bioinformation. 2012;8(1):48-57. Epub 2012 Jan 6.

9.

Antimicrobial proteins from snake venoms: direct bacterial damage and activation of innate immunity against Staphylococcus aureus skin infection.

Samy RP, Stiles BG, Gopalakrishnakone P, Chow VT.

Curr Med Chem. 2011;18(33):5104-13. Review.

PMID:
22050758
10.

Therapeutic potential of peptides with neutralizing ability towards the venom and toxin (CaTx-I) of crotalus adamanteus.

Samy RP, Thwin MM, Stiles BG, Bow H, Chow VT, Gopalakrishnakone P.

Curr Top Med Chem. 2011;11(20):2540-55.

PMID:
21682682
11.

Evaluation of antibacterial activity of proteins and peptides using a specific animal model for wound healing.

Samy RP, Thwin MM, Chow VT, Bow H, Gopalakrishnakone P.

Methods Mol Biol. 2011;716:245-65. doi: 10.1007/978-1-61779-012-6_15.

PMID:
21318911
12.

Identification and characterization of a phospholipase A2 from the venom of the Saw-scaled viper: Novel bactericidal and membrane damaging activities.

Perumal Samy R, Gopalakrishnakone P, Bow H, Puspharaj PN, Chow VT.

Biochimie. 2010 Dec;92(12):1854-66. doi: 10.1016/j.biochi.2010.07.012. Epub 2010 Aug 17.

PMID:
20723574
13.

Cloning and molecular characterization of BmHYA1, a novel hyaluronidase from the venom of Chinese red scorpion Buthus martensi Karsch.

Feng L, Gao R, Meng J, Gopalakrishnakone P.

Toxicon. 2010 Sep 1;56(3):474-9. doi: 10.1016/j.toxicon.2010.04.009. Epub 2010 Apr 24.

PMID:
20417653
14.

The Global Snake Bite Initiative: an antidote for snake bite.

Williams D, Gutiérrez JM, Harrison R, Warrell DA, White J, Winkel KD, Gopalakrishnakone P; Global Snake Bite Initiative Working Group; International Society on Toxinology.

Lancet. 2010 Jan 2;375(9708):89-91. doi: 10.1016/S0140-6736(09)61159-4. No abstract available.

PMID:
20109867
15.

Venom neutralization by purified bioactive molecules: Synthetic peptide derivatives of the endogenous PLA(2) inhibitory protein PIP (a mini-review).

Thwin MM, Samy RP, Satyanarayanajois SD, Gopalakrishnakone P.

Toxicon. 2010 Dec 15;56(7):1275-83. doi: 10.1016/j.toxicon.2009.12.023. Epub 2010 Jan 4. Review.

PMID:
20045432
16.
17.

ETS2 regulating neurodegenerative signaling pathway of human neuronal (SH-SY5Y) cells exposed to single and repeated low-dose sarin (GB).

Pachiappan A, Thwin MM, Weng Keong L, Lee FK, Manikandan J, Sivakumar V, Gopalakrishnakone P.

Chem Res Toxicol. 2009 Jun;22(6):990-6. doi: 10.1021/tx8003467.

PMID:
19522546
18.

A compilation of bioactive compounds from Ayurveda.

Samy RP, Pushparaj PN, Gopalakrishnakone P.

Bioinformation. 2008;3(3):100-10. Epub 2008 Nov 2.

19.

Transcriptome profiling of neuronal model cell PC12 from rat pheochromocytoma.

Saminathan R, Pachiappan A, Feng L, Rowan EG, Gopalakrishnakone P.

Cell Mol Neurobiol. 2009 Jun;29(4):533-48. doi: 10.1007/s10571-009-9345-y. Epub 2009 Feb 5.

PMID:
19194798
20.

Medical education in a flat world.

Tam J, Goh PS, Siow WY, Gopalakrishnakone P, Zubair A.

Ann Acad Med Singapore. 2008 Dec;37(12):991-2. No abstract available.

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