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Results: 1 to 20 of 339

1.

Synthesis and Pharmacological Characterization of C4-Disubstituted Analogs of 1S,2S,5R,6S-2-Aminobicyclo[3.1.0]hexane-2,6-Dicarboxylate: Identification of a Potent, Selective Metabotropic Glutamate Receptor Agonist and Determination of Agonist-Bound Human mGlu2 and mGlu3 Amino Terminal Domain Structures.

Monn JA, Prieto L, Taboada L, Pedregal C, Hao J, Reinhard MR, Henry SS, Goldsmith PJ, Beadle CD, Walton L, Man T, Rudyk H, Clark B, Tupper D, Baker SR, Lamas C, Montero C, Marcos A, Blanco J, Bures M, Clawson DK, Atwell S, Lu F, Wang J, Russell M, Heinz BA, Wang X, Carter JH, Xiang C, Catlow JT, Swanson S, Johnson MP, Knopp KL, Simmons RM, Johnson BG, Shaw DB, McKinzie DL.

J Med Chem. 2015 Jan 20. [Epub ahead of print]

PMID:
25602126
[PubMed - as supplied by publisher]
2.

Major adverse maternal cardiovascular-related events in those with aortopathies. What should we expect?

Bradley EA, Zaidi AN, Goldsmith P, Sisk T, Colombo D, Roble S, Bradley D, Daniels C.

Int J Cardiol. 2014 Nov 15;177(1):229-34. doi: 10.1016/j.ijcard.2014.09.018. Epub 2014 Sep 22.

PMID:
25499384
[PubMed - in process]
3.

Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity.

Ou O, Huppi K, Chakka S, Gehlhaus K, Dubois W, Patel J, Chen J, Mackiewicz M, Jones TL, Pitt JJ, Martin SE, Goldsmith P, Simmons JK, Mock BA, Caplen NJ.

Cancer Lett. 2014 Nov 28;354(2):336-47. doi: 10.1016/j.canlet.2014.08.043. Epub 2014 Sep 1.

PMID:
25193464
[PubMed - in process]
4.

Brightfield proximity ligation assay reveals both canonical and mixed transforming growth factor-β/bone morphogenetic protein Smad signaling complexes in tissue sections.

Flanders KC, Heger CD, Conway C, Tang B, Sato M, Dengler SL, Goldsmith PK, Hewitt SM, Wakefield LM.

J Histochem Cytochem. 2014 Dec;62(12):846-63. doi: 10.1369/0022155414550163. Epub 2014 Aug 20.

PMID:
25141865
[PubMed - indexed for MEDLINE]
Free Article
5.

Alternative viewpoint: preparation for residency.

Knapp KK, Mészáros K, Goldsmith PC, McCarter GC, Hester EK, McBane SE, Bottorff MB, Carnes TA, Dell K, Gonyeau MJ, Greco AJ, McConnell KJ, Skaar DJ, Splinter MY, Trujillo TC.

Pharmacotherapy. 2014 Aug;34(8):e157-8. doi: 10.1002/phar.1475. No abstract available.

PMID:
25112527
[PubMed - in process]
6.

Optimal reaction coordinate as a biomarker for the dynamics of recovery from kidney transplant.

Krivov SV, Fenton H, Goldsmith PJ, Prasad RK, Fisher J, Paci E.

PLoS Comput Biol. 2014 Jun 26;10(6):e1003685. doi: 10.1371/journal.pcbi.1003685. eCollection 2014 Jun.

PMID:
24967678
[PubMed - in process]
Free PMC Article
7.

Molecular systems pharmacology: isoelectric focusing signature of protein kinase Cδ provides an integrated measure of its modulation in response to ligands.

Kedei N, Chen JQ, Herrmann MA, Telek A, Goldsmith PK, Petersen ME, Keck GE, Blumberg PM.

J Med Chem. 2014 Jun 26;57(12):5356-69. doi: 10.1021/jm500417b. Epub 2014 Jun 6.

PMID:
24906106
[PubMed - indexed for MEDLINE]
8.

Land usage attributed to corn ethanol production in the United States: sensitivity to technological advances in corn grain yield, ethanol conversion, and co-product utilization.

Mumm RH, Goldsmith PD, Rausch KD, Stein HH.

Biotechnol Biofuels. 2014 Apr 12;7:61. doi: 10.1186/1754-6834-7-61. eCollection 2014.

PMID:
24725504
[PubMed]
Free PMC Article
9.
10.

Target and nontarget effects of novel "triple-stacked" Bt-transgenic cotton 1: canopy arthropod communities.

Whitehouse ME, Wilson LJ, Davies AP, Cross D, Goldsmith P, Thompson A, Harden S, Baker G.

Environ Entomol. 2014 Feb;43(1):218-41. doi: 10.1603/EN13167.

PMID:
24472211
[PubMed - indexed for MEDLINE]
11.

Functional characterisation of the maturation of the blood-brain barrier in larval zebrafish.

Fleming A, Diekmann H, Goldsmith P.

PLoS One. 2013 Oct 16;8(10):e77548. doi: 10.1371/journal.pone.0077548. eCollection 2013.

PMID:
24147021
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Capillary isoelectric-focusing immunoassays to study dynamic oncoprotein phosphorylation and drug response to targeted therapies in non-small cell lung cancer.

Chen JQ, Lee JH, Herrmann MA, Park KS, Heldman MR, Goldsmith PK, Wang Y, Giaccone G.

Mol Cancer Ther. 2013 Nov;12(11):2601-13. doi: 10.1158/1535-7163.MCT-13-0074. Epub 2013 Aug 26.

PMID:
23979919
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Absolute quantitation of endogenous proteins with precision and accuracy using a capillary Western system.

Chen JQ, Heldman MR, Herrmann MA, Kedei N, Woo W, Blumberg PM, Goldsmith PK.

Anal Biochem. 2013 Nov 1;442(1):97-103. doi: 10.1016/j.ab.2013.07.022. Epub 2013 Jul 26.

PMID:
23896461
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

TUSC1, a putative tumor suppressor gene, reduces tumor cell growth in vitro and tumor growth in vivo.

Shan Z, Shakoori A, Bodaghi S, Goldsmith P, Jin J, Wiest JS.

PLoS One. 2013 Jun 11;8(6):e66114. doi: 10.1371/journal.pone.0066114. Print 2013.

PMID:
23776618
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in Saccharomyces cerevisiae.

Boeckmann L, Takahashi Y, Au WC, Mishra PK, Choy JS, Dawson AR, Szeto MY, Waybright TJ, Heger C, McAndrew C, Goldsmith PK, Veenstra TD, Baker RE, Basrai MA.

Mol Biol Cell. 2013 Jun;24(12):2034-44. doi: 10.1091/mbc.E12-12-0893. Epub 2013 May 1.

PMID:
23637466
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

NCCN's value pathways: the drive for quality cancer care.

Goldsmith PJ.

J Natl Compr Canc Netw. 2013 Feb 1;11(2):119-20. No abstract available.

PMID:
23411377
[PubMed - indexed for MEDLINE]
17.

Label-retaining liver cancer cells are relatively resistant to sorafenib.

Xin HW, Ambe CM, Hari DM, Wiegand GW, Miller TC, Chen JQ, Anderson AJ, Ray S, Mullinax JE, Koizumi T, Langan RC, Burka D, Herrmann MA, Goldsmith PK, Stojadinovic A, Rudloff U, Thorgeirsson SS, Avital I.

Gut. 2013 Dec;62(12):1777-86. doi: 10.1136/gutjnl-2012-303261. Epub 2013 Feb 14.

PMID:
23411027
[PubMed - indexed for MEDLINE]
18.

Metastasis of colorectal adenocarcinoma to the thyroid: a case report and review of the literature.

Goatman C, Goldsmith PJ, Antonopoulos V, Ali B.

Case Rep Surg. 2012;2012:179407. doi: 10.1155/2012/179407. Epub 2012 Nov 28.

PMID:
23243548
[PubMed]
Free PMC Article
19.

Extreme achalasia presenting as anorexia nervosa.

Goldsmith PJ, Decadt B.

Case Rep Surg. 2012;2012:985454. doi: 10.1155/2012/985454. Epub 2012 Oct 4.

PMID:
23091768
[PubMed]
Free PMC Article
20.

Characterization of Δ7/11, a functional prolactin-binding protein.

Fleming JM, Ginsburg E, McAndrew CW, Heger CD, Cheston L, Rodriguez-Canales J, Vonderhaar BK, Goldsmith P.

J Mol Endocrinol. 2012 Dec 31;50(1):79-90. doi: 10.1530/JME-12-0201. Print 2013 Feb.

PMID:
23048206
[PubMed - indexed for MEDLINE]
Free PMC Article
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