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Items: 1 to 20 of 39

1.

Melanoma associated antigen (MAGE)-A3 promotes cell proliferation and chemotherapeutic drug resistance in gastric cancer.

Xie C, Subhash VV, Datta A, Liem N, Tan SH, Yeo MS, Tan WL, Koh V, Yan FL, Wong FY, Wong WK, So J, Tan IB, Padmanabhan N, Yap CT, Tan P, Goh LK, Yong WP.

Cell Oncol (Dordr). 2016 Apr;39(2):175-86. doi: 10.1007/s13402-015-0261-5. Epub 2016 Feb 11.

PMID:
26868260
2.

Molecular characterization of hepatocarcinogenesis using mouse models.

Teoh WW, Xie M, Vijayaraghavan A, Yaligar J, Tong WM, Goh LK, Sabapathy K.

Dis Model Mech. 2015 Jul 1;8(7):743-53. doi: 10.1242/dmm.017624. Epub 2015 May 5.

3.

Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome.

Dulloo I, Phang BH, Othman R, Tan SY, Vijayaraghavan A, Goh LK, Martin-Lopez M, Marques MM, Li CW, Wang de Y, Marín MC, Xian W, McKeon F, Sabapathy K.

Nat Cell Biol. 2015 Apr;17(4):511-23. doi: 10.1038/ncb3130. Epub 2015 Mar 16.

PMID:
25774835
4.

An integrative approach identified genes associated with drug response in gastric cancer.

Zhou J, Yong WP, Yap CS, Vijayaraghavan A, Sinha RA, Singh BK, Xiu S, Manesh S, Ngo A, Lim A, Ang C, Xie C, Wong FY, Lin SJ, Wan WK, Tan IB, Flotow H, Tan P, Lim KH, Yen PM, Goh LK.

Carcinogenesis. 2015 Apr;36(4):441-51. doi: 10.1093/carcin/bgv014. Epub 2015 Mar 5.

5.

TOMM40 alterations in Alzheimer's disease over a 2-year follow-up period.

Goh LK, Lim WS, Teo S, Vijayaraghavan A, Chan M, Tay L, Ng TP, Tan CH, Lee TS, Chong MS.

J Alzheimers Dis. 2015;44(1):57-61. doi: 10.3233/JAD-141590.

PMID:
25201778
6.

Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development.

Chia NY, Deng N, Das K, Huang D, Hu L, Zhu Y, Lim KH, Lee MH, Wu J, Sam XX, Tan GS, Wan WK, Yu W, Gan A, Tan AL, Tay ST, Soo KC, Wong WK, Dominguez LT, Ng HH, Rozen S, Goh LK, Teh BT, Tan P.

Gut. 2015 May;64(5):707-19. doi: 10.1136/gutjnl-2013-306596. Epub 2014 Jul 22.

PMID:
25053715
7.

Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements.

Muratani M, Deng N, Ooi WF, Lin SJ, Xing M, Xu C, Qamra A, Tay ST, Malik S, Wu J, Lee MH, Zhang S, Tan LL, Chua H, Wong WK, Ong HS, Ooi LL, Chow PK, Chan WH, Soo KC, Goh LK, Rozen S, Teh BT, Yu Q, Ng HH, Tan P.

Nat Commun. 2014 Jul 10;5:4361. doi: 10.1038/ncomms5361.

PMID:
25008978
8.

Diagnostic and prognostic utility of a DNA hypermethylated gene signature in prostate cancer.

Goh LK, Liem N, Vijayaraghavan A, Chen G, Lim PL, Tay KJ, Chang M, Low JS, Joshi A, Huang HH, Kalaw E, Tan PH, Hsieh WS, Yong WP, Alumkal J, Sim HG.

PLoS One. 2014 Mar 13;9(3):e91666. doi: 10.1371/journal.pone.0091666. eCollection 2014.

9.

Optimizing Ventana chromogenic dual in-situ hybridization for mucinous epithelial ovarian cancer.

Li X, Chew SH, Chay WY, Lim-Tan SK, Goh LK.

BMC Res Notes. 2013 Dec 28;6:562. doi: 10.1186/1756-0500-6-562.

10.

Enhancement of stress tolerance in the polyhydroxyalkanoate producers without mobilization of the accumulated granules.

Goh LK, Purama RK, Sudesh K.

Appl Biochem Biotechnol. 2014 Feb;172(3):1585-98. doi: 10.1007/s12010-013-0634-z. Epub 2013 Nov 14.

PMID:
24233544
11.

Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil.

Lei Z, Tan IB, Das K, Deng N, Zouridis H, Pattison S, Chua C, Feng Z, Guan YK, Ooi CH, Ivanova T, Zhang S, Lee M, Wu J, Ngo A, Manesh S, Tan E, Teh BT, So JB, Goh LK, Boussioutas A, Lim TK, Flotow H, Tan P, Rozen SG.

Gastroenterology. 2013 Sep;145(3):554-65. doi: 10.1053/j.gastro.2013.05.010. Epub 2013 May 14.

PMID:
23684942
12.

Muscarinic cholinergic receptor (M2) plays a crucial role in the development of myopia in mice.

Barathi VA, Kwan JL, Tan QS, Weon SR, Seet LF, Goh LK, Vithana EN, Beuerman RW.

Dis Model Mech. 2013 Sep;6(5):1146-58. doi: 10.1242/dmm.010967. Epub 2013 May 2.

13.

Endocytosis of receptor tyrosine kinases.

Goh LK, Sorkin A.

Cold Spring Harb Perspect Biol. 2013 May 1;5(5):a017459. doi: 10.1101/cshperspect.a017459. Review.

14.

HER2 amplification and clinicopathological characteristics in a large Asian cohort of rare mucinous ovarian cancer.

Chay WY, Chew SH, Ong WS, Busmanis I, Li X, Thung S, Ngo L, Lim SL, Lim YK, Chia YN, Koh E, Pang C, Soh LT, Wang J, Ho TH, Tay SK, Lim-Tan SK, Lim KH, Chia JW, Goh LK.

PLoS One. 2013 Apr 19;8(4):e61565. doi: 10.1371/journal.pone.0061565. Print 2013.

15.

Gene expression profiling of peripheral blood leukocytes shows consistent longitudinal downregulation of TOMM40 and upregulation of KIR2DL5A, PLOD1, and SLC2A8 among fast progressors in early Alzheimer's disease.

Chong MS, Goh LK, Lim WS, Chan M, Tay L, Chen G, Feng L, Ng TP, Tan CH, Lee TS.

J Alzheimers Dis. 2013;34(2):399-405. doi: 10.3233/JAD-121621.

PMID:
23234877
16.

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.

Horikoshi M, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ, Bradfield JP, St Pourcain B, Evans DM, Charoen P, Kaakinen M, Cousminer DL, Lehtimäki T, Kreiner-Møller E, Warrington NM, Bustamante M, Feenstra B, Berry DJ, Thiering E, Pfab T, Barton SJ, Shields BM, Kerkhof M, van Leeuwen EM, Fulford AJ, Kutalik Z, Zhao JH, den Hoed M, Mahajan A, Lindi V, Goh LK, Hottenga JJ, Wu Y, Raitakari OT, Harder MN, Meirhaeghe A, Ntalla I, Salem RM, Jameson KA, Zhou K, Monies DM, Lagou V, Kirin M, Heikkinen J, Adair LS, Alkuraya FS, Al-Odaib A, Amouyel P, Andersson EA, Bennett AJ, Blakemore AI, Buxton JL, Dallongeville J, Das S, de Geus EJ, Estivill X, Flexeder C, Froguel P, Geller F, Godfrey KM, Gottrand F, Groves CJ, Hansen T, Hirschhorn JN, Hofman A, Hollegaard MV, Hougaard DM, Hyppönen E, Inskip HM, Isaacs A, Jørgensen T, Kanaka-Gantenbein C, Kemp JP, Kiess W, Kilpeläinen TO, Klopp N, Knight BA, Kuzawa CW, McMahon G, Newnham JP, Niinikoski H, Oostra BA, Pedersen L, Postma DS, Ring SM, Rivadeneira F, Robertson NR, Sebert S, Simell O, Slowinski T, Tiesler CM, Tönjes A, Vaag A, Viikari JS, Vink JM, Vissing NH, Wareham NJ, Willemsen G, Witte DR, Zhang H, Zhao J; Meta-Analyses of Glucose- and Insulin-related traits Consortium (MAGIC), Wilson JF, Stumvoll M, Prentice AM, Meyer BF, Pearson ER, Boreham CA, Cooper C, Gillman MW, Dedoussis GV, Moreno LA, Pedersen O, Saarinen M, Mohlke KL, Boomsma DI, Saw SM, Lakka TA, Körner A, Loos RJ, Ong KK, Vollenweider P, van Duijn CM, Koppelman GH, Hattersley AT, Holloway JW, Hocher B, Heinrich J, Power C, Melbye M, Guxens M, Pennell CE, Bønnelykke K, Bisgaard H, Eriksson JG, Widén E, Hakonarson H, Uitterlinden AG, Pouta A, Lawlor DA, Smith GD, Frayling TM, McCarthy MI, Grant SF, Jaddoe VW, Jarvelin MR, Timpson NJ, Prokopenko I, Freathy RM; Early Growth Genetics (EGG) Consortium.

Nat Genet. 2013 Jan;45(1):76-82. doi: 10.1038/ng.2477. Epub 2012 Dec 2.

17.

Methylation subtypes and large-scale epigenetic alterations in gastric cancer.

Zouridis H, Deng N, Ivanova T, Zhu Y, Wong B, Huang D, Wu YH, Wu Y, Tan IB, Liem N, Gopalakrishnan V, Luo Q, Wu J, Lee M, Yong WP, Goh LK, Teh BT, Rozen S, Tan P.

Sci Transl Med. 2012 Oct 17;4(156):156ra140. doi: 10.1126/scitranslmed.3004504.

18.

Genetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer library.

Zhou J, Chen GB, Tang YC, Sinha RA, Wu Y, Yap CS, Wang G, Hu J, Xia X, Tan P, Goh LK, Yen PM.

BMC Med Genomics. 2012 Aug 9;5:34. doi: 10.1186/1755-8794-5-34.

19.

Uterine leiomyosarcoma in asian patients: validation of the revised Federation of gynecology and obstetrics staging system and identification of prognostic classifiers.

Tan PS, Koh E, Pang C, Ong WS, Ngo L, Soh LT, Quek R, Chay WY, Ho TH, Tay SK, Chew SH, Lim-Tan SK, Khoo-Tan H, Lim SL, Busmanis I, Goh LK, Chia YN, Chia WK, Lim T.

Oncologist. 2012;17(10):1286-93. doi: 10.1634/theoncologist.2012-0124. Epub 2012 Jul 24.

20.

Evaluation of gene expression profiles and pathways underlying postnatal development in mouse sclera.

Lim W, Kwan JL, Goh LK, Beuerman RW, Barathi VA.

Mol Vis. 2012;18:1436-48. Epub 2012 Jun 2.

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