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Manipulation of interleukin-1β and interleukin-18 production by Yersinia pestis effectors YopJ and YopM and redundant impact on virulence.

Ratner D, Orning MP, Starheim KK, Marty-Roix R, Proulx MK, Goguen JD, Lien E.

J Biol Chem. 2016 Jul 29;291(31):16417. doi: 10.1074/jbc.A115.697698. No abstract available.


Reply to Gelfand and Cleveland.

Proulx MK, Ellison RT 3rd, Goguen JD.

J Infect Dis. 2016 Mar 8. pii: jiw052. [Epub ahead of print] No abstract available.


Manipulation of Interleukin-1β and Interleukin-18 Production by Yersinia pestis Effectors YopJ and YopM and Redundant Impact on Virulence.

Ratner D, Orning MP, Starheim KK, Marty-Roix R, Proulx MK, Goguen JD, Lien E.

J Biol Chem. 2016 May 6;291(19):9894-905. doi: 10.1074/jbc.M115.697698. Epub 2016 Feb 16. Erratum in: J Biol Chem. 2016 Jul 29;291(31):16417.


Reversion From Methicillin Susceptibility to Methicillin Resistance in Staphylococcus aureus During Treatment of Bacteremia.

Proulx MK, Palace SG, Gandra S, Torres B, Weir S, Stiles T, Ellison RT 3rd, Goguen JD.

J Infect Dis. 2016 Mar 15;213(6):1041-8. doi: 10.1093/infdis/jiv512. Epub 2015 Oct 26.


Planetary surface photometry and imaging: progress and perspectives.

Goguen JD.

Rep Prog Phys. 2014 Oct;77(10):104901. doi: 10.1088/0034-4885/77/10/104901. Epub 2014 Oct 14. Review.


Genome-wide mutant fitness profiling identifies nutritional requirements for optimal growth of Yersinia pestis in deep tissue.

Palace SG, Proulx MK, Lu S, Baker RE, Goguen JD.

MBio. 2014 Aug 19;5(4). pii: e01385-14. doi: 10.1128/mBio.01385-14.


Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.

Weng D, Marty-Roix R, Ganesan S, Proulx MK, Vladimer GI, Kaiser WJ, Mocarski ES, Pouliot K, Chan FK, Kelliher MA, Harris PA, Bertin J, Gough PJ, Shayakhmetov DM, Goguen JD, Fitzgerald KA, Silverman N, Lien E.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7391-6. doi: 10.1073/pnas.1403477111. Epub 2014 May 5.


The NLRP12 inflammasome recognizes Yersinia pestis.

Vladimer GI, Weng D, Paquette SW, Vanaja SK, Rathinam VA, Aune MH, Conlon JE, Burbage JJ, Proulx MK, Liu Q, Reed G, Mecsas JC, Iwakura Y, Bertin J, Goguen JD, Fitzgerald KA, Lien E.

Immunity. 2012 Jul 27;37(1):96-107. doi: 10.1016/j.immuni.2012.07.006. Erratum in: Immunity. 2012 Sep 21;37(3):588.


Involvement of CD8+ T cell-mediated immune responses in LcrV DNA vaccine induced protection against lethal Yersinia pestis challenge.

Wang S, Goguen JD, Li F, Lu S.

Vaccine. 2011 Sep 9;29(39):6802-9. doi: 10.1016/j.vaccine.2010.12.062. Epub 2011 Jan 1.


No better time to FRET: shedding light on host pathogen interactions.

Hayward RD, Goguen JD, Leong JM.

J Biol. 2010;9(2):12. doi: 10.1186/jbiol225. Epub 2010 Feb 18. Review.


Antigen engineering can play a critical role in the protective immunity elicited by Yersinia pestis DNA vaccines.

Wang S, Mboudjeka I, Goguen JD, Lu S.

Vaccine. 2010 Feb 23;28(8):2011-9. doi: 10.1016/j.vaccine.2009.10.059.


Targeting type III secretion in Yersinia pestis.

Pan NJ, Brady MJ, Leong JM, Goguen JD.

Antimicrob Agents Chemother. 2009 Feb;53(2):385-92. doi: 10.1128/AAC.00670-08. Epub 2008 Nov 17.


Relative immunogenicity and protection potential of candidate Yersinia Pestis antigens against lethal mucosal plague challenge in Balb/C mice.

Wang S, Joshi S, Mboudjeka I, Liu F, Ling T, Goguen JD, Lu S.

Vaccine. 2008 Mar 20;26(13):1664-74. doi: 10.1016/j.vaccine.2008.01.024. Epub 2008 Feb 4.


Fibrin and fibrinolysis in infection and host defense.

Degen JL, Bugge TH, Goguen JD.

J Thromb Haemost. 2007 Jul;5 Suppl 1:24-31. Review.


Evaluation of the role of LcrV-Toll-like receptor 2-mediated immunomodulation in the virulence of Yersinia pestis.

Pouliot K, Pan N, Wang S, Lu S, Lien E, Goguen JD.

Infect Immun. 2007 Jul;75(7):3571-80. Epub 2007 Apr 16.


Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response.

Montminy SW, Khan N, McGrath S, Walkowicz MJ, Sharp F, Conlon JE, Fukase K, Kusumoto S, Sweet C, Miyake K, Akira S, Cotter RJ, Goguen JD, Lien E.

Nat Immunol. 2006 Oct;7(10):1066-73. Epub 2006 Sep 17.


New approaches and old problems in the shadow of bioterrorism.

Leong JM, Parveen N, Goguen JD.

Trends Microbiol. 2002 Mar;10(3):112-4. No abstract available.


RNA expression patterns change dramatically in human neutrophils exposed to bacteria.

Subrahmanyam YV, Yamaga S, Prashar Y, Lee HH, Hoe NP, Kluger Y, Gerstein M, Goguen JD, Newburger PE, Weissman SM.

Blood. 2001 Apr 15;97(8):2457-68.


Proteases and bacterial virulence: a view from the trenches.

Goguen JD, Hoe NP, Subrahmanyam YV.

Infect Agents Dis. 1995 Mar;4(1):47-54. Review.

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