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Results: 1 to 20 of 46

1.

Effect of fixation procedures on the fluorescence lifetimes of Aequorea victoria derived fluorescent proteins.

Joosen L, Hink MA, Gadella TW Jr, Goedhart J.

J Microsc. 2014 Dec;256(3):166-76. doi: 10.1111/jmi.12168. Epub 2014 Sep 1.

PMID:
25179491
[PubMed - in process]
2.

Development of FRET biosensors for mammalian and plant systems.

Hamers D, van Voorst Vader L, Borst JW, Goedhart J.

Protoplasma. 2014 Mar;251(2):333-47. doi: 10.1007/s00709-013-0590-z. Epub 2013 Dec 12. Review.

PMID:
24337770
[PubMed - indexed for MEDLINE]
3.

SCA14 mutation V138E leads to partly unfolded PKCγ associated with an exposed C-terminus, altered kinetics, phosphorylation and enhanced insolubilization.

Jezierska J, Goedhart J, Kampinga HH, Reits EA, Verbeek DS.

J Neurochem. 2014 Mar;128(5):741-51. doi: 10.1111/jnc.12491. Epub 2013 Nov 13.

PMID:
24134140
[PubMed - indexed for MEDLINE]
4.

Optimization of fluorescent proteins.

Bindels DS, Goedhart J, Hink MA, van Weeren L, Joosen L, Gadella TW Jr.

Methods Mol Biol. 2014;1076:371-417. doi: 10.1007/978-1-62703-649-8_16.

PMID:
24108635
[PubMed - indexed for MEDLINE]
5.

An introduction to fluorescence imaging techniques geared towards biosensor applications.

Goedhart J, Hink MA, Jalink K.

Methods Mol Biol. 2014;1071:17-28. doi: 10.1007/978-1-62703-622-1_2. Review.

PMID:
24052377
[PubMed - indexed for MEDLINE]
6.

Signaling efficiency of Gαq through its effectors p63RhoGEF and GEFT depends on their subcellular location.

Goedhart J, van Unen J, Adjobo-Hermans MJ, Gadella TW Jr.

Sci Rep. 2013;3:2284. doi: 10.1038/srep02284.

PMID:
23884432
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The DNAJB6 and DNAJB8 protein chaperones prevent intracellular aggregation of polyglutamine peptides.

Gillis J, Schipper-Krom S, Juenemann K, Gruber A, Coolen S, van den Nieuwendijk R, van Veen H, Overkleeft H, Goedhart J, Kampinga HH, Reits EA.

J Biol Chem. 2013 Jun 14;288(24):17225-37. doi: 10.1074/jbc.M112.421685. Epub 2013 Apr 23.

PMID:
23612975
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq.

Adjobo-Hermans MJ, Crosby KC, Putyrski M, Bhageloe A, van Weeren L, Schultz C, Goedhart J, Gadella TW Jr.

Cell Signal. 2013 Jan;25(1):255-63. doi: 10.1016/j.cellsig.2012.09.022. Epub 2012 Sep 21.

PMID:
23006664
[PubMed - indexed for MEDLINE]
9.

Structure of a fluorescent protein from Aequorea victoria bearing the obligate-monomer mutation A206K.

von Stetten D, Noirclerc-Savoye M, Goedhart J, Gadella TW Jr, Royant A.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Aug 1;68(Pt 8):878-82. doi: 10.1107/S1744309112028667. Epub 2012 Jul 26.

PMID:
22869113
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%.

Goedhart J, von Stetten D, Noirclerc-Savoye M, Lelimousin M, Joosen L, Hink MA, van Weeren L, Gadella TW Jr, Royant A.

Nat Commun. 2012 Mar 20;3:751. doi: 10.1038/ncomms1738.

PMID:
22434194
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Quantitative co-expression of proteins at the single cell level--application to a multimeric FRET sensor.

Goedhart J, van Weeren L, Adjobo-Hermans MJ, Elzenaar I, Hink MA, Gadella TW Jr.

PLoS One. 2011;6(11):e27321. doi: 10.1371/journal.pone.0027321. Epub 2011 Nov 17.

PMID:
22114669
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Bypassing GPCRs with chemical dimerizers.

Goedhart J, Gadella TW Jr.

Chem Biol. 2011 Sep 23;18(9):1067-8. doi: 10.1016/j.chembiol.2011.09.004. No abstract available.

PMID:
21944742
[PubMed]
Free Article
13.

Understanding why older people develop a wish to die: a qualitative interview study.

Rurup ML, Pasman HR, Goedhart J, Deeg DJ, Kerkhof AJ, Onwuteaka-Philipsen BD.

Crisis. 2011;32(4):204-16. doi: 10.1027/0227-5910/a000078.

PMID:
21940258
[PubMed - indexed for MEDLINE]
14.

Recruiting end-of-life cancer patients in the Netherlands for a study on suffering and euthanasia requests.

Ruijs CD, Goedhart J, Kerkhof AJ, van der Wal G, Onwuteaka-Philipsen BD.

Fam Pract. 2011 Dec;28(6):689-95. doi: 10.1093/fampra/cmr035. Epub 2011 Jun 15.

PMID:
21677047
[PubMed - indexed for MEDLINE]
Free Article
15.

Real-time visualization of heterotrimeric G protein Gq activation in living cells.

Adjobo-Hermans MJ, Goedhart J, van Weeren L, Nijmeijer S, Manders EM, Offermanns S, Gadella TW Jr.

BMC Biol. 2011 May 27;9:32. doi: 10.1186/1741-7007-9-32.

PMID:
21619590
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A mTurquoise-based cAMP sensor for both FLIM and ratiometric read-out has improved dynamic range.

Klarenbeek JB, Goedhart J, Hink MA, Gadella TW, Jalink K.

PLoS One. 2011 Apr 29;6(4):e19170. doi: 10.1371/journal.pone.0019170.

PMID:
21559477
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Imaging lipids in living cells.

Schultz C, Neef AB, Gadella TW Jr, Goedhart J.

Cold Spring Harb Protoc. 2010 Jul 1;2010(7):pdb.top83. doi: 10.1101/pdb.top83.

PMID:
20647368
[PubMed - indexed for MEDLINE]
18.

Labeling lipids for imaging in live cells.

Schultz C, Neef AB, Gadella TW Jr, Goedhart J.

Cold Spring Harb Protoc. 2010 Jul 1;2010(7):pdb.prot5459. doi: 10.1101/pdb.prot5459.

PMID:
20647363
[PubMed - indexed for MEDLINE]
19.

Labeling lipids for imaging in fixed cells.

Schultz C, Neef AB, Gadella TW Jr, Goedhart J.

Cold Spring Harb Protoc. 2010 Jul 1;2010(7):pdb.prot5458. doi: 10.1101/pdb.prot5458.

PMID:
20647362
[PubMed - indexed for MEDLINE]
20.

Transfection of cells with DNA encoding a visible fluorescent protein-tagged lipid-binding domain.

Schultz C, Neef AB, Gadella TW Jr, Goedhart J.

Cold Spring Harb Protoc. 2010 Jul 1;2010(7):pdb.prot5457. doi: 10.1101/pdb.prot5457.

PMID:
20647361
[PubMed - indexed for MEDLINE]
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