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Results: 1 to 20 of 45

1.

Development of FRET biosensors for mammalian and plant systems.

Hamers D, van Voorst Vader L, Borst JW, Goedhart J.

Protoplasma. 2014 Mar;251(2):333-47. doi: 10.1007/s00709-013-0590-z. Epub 2013 Dec 12.

PMID:
24337770
[PubMed - in process]
2.

SCA14 mutation V138E leads to partly unfolded PKCγ associated with an exposed C-terminus, altered kinetics, phosphorylation and enhanced insolubilization.

Jezierska J, Goedhart J, Kampinga HH, Reits EA, Verbeek DS.

J Neurochem. 2014 Mar;128(5):741-51. doi: 10.1111/jnc.12491. Epub 2013 Nov 13.

PMID:
24134140
[PubMed - indexed for MEDLINE]
3.

Optimization of fluorescent proteins.

Bindels DS, Goedhart J, Hink MA, van Weeren L, Joosen L, Gadella TW Jr.

Methods Mol Biol. 2014;1076:371-417. doi: 10.1007/978-1-62703-649-8_16.

PMID:
24108635
[PubMed - indexed for MEDLINE]
4.

An introduction to fluorescence imaging techniques geared towards biosensor applications.

Goedhart J, Hink MA, Jalink K.

Methods Mol Biol. 2014;1071:17-28. doi: 10.1007/978-1-62703-622-1_2. Review.

PMID:
24052377
[PubMed - indexed for MEDLINE]
5.

Signaling efficiency of Gαq through its effectors p63RhoGEF and GEFT depends on their subcellular location.

Goedhart J, van Unen J, Adjobo-Hermans MJ, Gadella TW Jr.

Sci Rep. 2013;3:2284. doi: 10.1038/srep02284.

PMID:
23884432
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The DNAJB6 and DNAJB8 protein chaperones prevent intracellular aggregation of polyglutamine peptides.

Gillis J, Schipper-Krom S, Juenemann K, Gruber A, Coolen S, van den Nieuwendijk R, van Veen H, Overkleeft H, Goedhart J, Kampinga HH, Reits EA.

J Biol Chem. 2013 Jun 14;288(24):17225-37. doi: 10.1074/jbc.M112.421685. Epub 2013 Apr 23.

PMID:
23612975
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq.

Adjobo-Hermans MJ, Crosby KC, Putyrski M, Bhageloe A, van Weeren L, Schultz C, Goedhart J, Gadella TW Jr.

Cell Signal. 2013 Jan;25(1):255-63. doi: 10.1016/j.cellsig.2012.09.022. Epub 2012 Sep 21.

PMID:
23006664
[PubMed - indexed for MEDLINE]
8.

Structure of a fluorescent protein from Aequorea victoria bearing the obligate-monomer mutation A206K.

von Stetten D, Noirclerc-Savoye M, Goedhart J, Gadella TW Jr, Royant A.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Aug 1;68(Pt 8):878-82. doi: 10.1107/S1744309112028667. Epub 2012 Jul 26.

PMID:
22869113
[PubMed - indexed for MEDLINE]
9.

Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%.

Goedhart J, von Stetten D, Noirclerc-Savoye M, Lelimousin M, Joosen L, Hink MA, van Weeren L, Gadella TW Jr, Royant A.

Nat Commun. 2012 Mar 20;3:751. doi: 10.1038/ncomms1738.

PMID:
22434194
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Quantitative co-expression of proteins at the single cell level--application to a multimeric FRET sensor.

Goedhart J, van Weeren L, Adjobo-Hermans MJ, Elzenaar I, Hink MA, Gadella TW Jr.

PLoS One. 2011;6(11):e27321. doi: 10.1371/journal.pone.0027321. Epub 2011 Nov 17.

PMID:
22114669
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Bypassing GPCRs with chemical dimerizers.

Goedhart J, Gadella TW Jr.

Chem Biol. 2011 Sep 23;18(9):1067-8. doi: 10.1016/j.chembiol.2011.09.004. No abstract available.

PMID:
21944742
[PubMed]
Free Article
12.

Understanding why older people develop a wish to die: a qualitative interview study.

Rurup ML, Pasman HR, Goedhart J, Deeg DJ, Kerkhof AJ, Onwuteaka-Philipsen BD.

Crisis. 2011;32(4):204-16. doi: 10.1027/0227-5910/a000078.

PMID:
21940258
[PubMed - indexed for MEDLINE]
13.

Recruiting end-of-life cancer patients in the Netherlands for a study on suffering and euthanasia requests.

Ruijs CD, Goedhart J, Kerkhof AJ, van der Wal G, Onwuteaka-Philipsen BD.

Fam Pract. 2011 Dec;28(6):689-95. doi: 10.1093/fampra/cmr035. Epub 2011 Jun 15.

PMID:
21677047
[PubMed - indexed for MEDLINE]
Free Article
14.

Real-time visualization of heterotrimeric G protein Gq activation in living cells.

Adjobo-Hermans MJ, Goedhart J, van Weeren L, Nijmeijer S, Manders EM, Offermanns S, Gadella TW Jr.

BMC Biol. 2011 May 27;9:32. doi: 10.1186/1741-7007-9-32.

PMID:
21619590
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A mTurquoise-based cAMP sensor for both FLIM and ratiometric read-out has improved dynamic range.

Klarenbeek JB, Goedhart J, Hink MA, Gadella TW, Jalink K.

PLoS One. 2011 Apr 29;6(4):e19170. doi: 10.1371/journal.pone.0019170.

PMID:
21559477
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Imaging lipids in living cells.

Schultz C, Neef AB, Gadella TW Jr, Goedhart J.

Cold Spring Harb Protoc. 2010 Jul 1;2010(7):pdb.top83. doi: 10.1101/pdb.top83.

PMID:
20647368
[PubMed - indexed for MEDLINE]
17.

Labeling lipids for imaging in live cells.

Schultz C, Neef AB, Gadella TW Jr, Goedhart J.

Cold Spring Harb Protoc. 2010 Jul 1;2010(7):pdb.prot5459. doi: 10.1101/pdb.prot5459.

PMID:
20647363
[PubMed - indexed for MEDLINE]
18.

Labeling lipids for imaging in fixed cells.

Schultz C, Neef AB, Gadella TW Jr, Goedhart J.

Cold Spring Harb Protoc. 2010 Jul 1;2010(7):pdb.prot5458. doi: 10.1101/pdb.prot5458.

PMID:
20647362
[PubMed - indexed for MEDLINE]
19.

Transfection of cells with DNA encoding a visible fluorescent protein-tagged lipid-binding domain.

Schultz C, Neef AB, Gadella TW Jr, Goedhart J.

Cold Spring Harb Protoc. 2010 Jul 1;2010(7):pdb.prot5457. doi: 10.1101/pdb.prot5457.

PMID:
20647361
[PubMed - indexed for MEDLINE]
20.

Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair.

Luijsterburg MS, von Bornstaedt G, Gourdin AM, Politi AZ, Moné MJ, Warmerdam DO, Goedhart J, Vermeulen W, van Driel R, Höfer T.

J Cell Biol. 2010 May 3;189(3):445-63. doi: 10.1083/jcb.200909175.

PMID:
20439997
[PubMed - indexed for MEDLINE]
Free PMC Article

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