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Results: 1 to 20 of 50

1.

Domain analysis of the Nematostella vectensis SNAIL ortholog reveals unique nucleolar localization that depends on the zinc-finger domains.

Dattoli AA, Hink MA, DuBuc TQ, Teunisse BJ, Goedhart J, Röttinger E, Postma M.

Sci Rep. 2015 Jul 20;5:12147. doi: 10.1038/srep12147.

2.

A local VE-cadherin and Trio-based signaling complex stabilizes endothelial junctions through Rac1.

Timmerman I, Heemskerk N, Kroon J, Schaefer A, van Rijssel J, Hoogenboezem M, van Unen J, Goedhart J, Gadella TW Jr, Yin T, Wu Y, Huveneers S, van Buul JD.

J Cell Sci. 2015 Aug 15;128(16):3041-54. doi: 10.1242/jcs.168674. Epub 2015 Jun 26.

PMID:
26116572
3.

A Perspective on Studying G-Protein-Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms.

van Unen J, Woolard J, Rinken A, Hoffmann C, Hill SJ, Goedhart J, Bruchas MR, Bouvier M, Adjobo-Hermans MJ.

Mol Pharmacol. 2015 Sep;88(3):589-95. doi: 10.1124/mol.115.098897. Epub 2015 May 13.

PMID:
25972446
4.

Fourth-generation epac-based FRET sensors for cAMP feature exceptional brightness, photostability and dynamic range: characterization of dedicated sensors for FLIM, for ratiometry and with high affinity.

Klarenbeek J, Goedhart J, van Batenburg A, Groenewald D, Jalink K.

PLoS One. 2015 Apr 14;10(4):e0122513. doi: 10.1371/journal.pone.0122513. eCollection 2015.

5.

Effect of fixation procedures on the fluorescence lifetimes of Aequorea victoria derived fluorescent proteins.

Joosen L, Hink MA, Gadella TW Jr, Goedhart J.

J Microsc. 2014 Dec;256(3):166-76. doi: 10.1111/jmi.12168. Epub 2014 Sep 1.

PMID:
25179491
6.

Development of FRET biosensors for mammalian and plant systems.

Hamers D, van Voorst Vader L, Borst JW, Goedhart J.

Protoplasma. 2014 Mar;251(2):333-47. doi: 10.1007/s00709-013-0590-z. Epub 2013 Dec 12. Review.

PMID:
24337770
7.

SCA14 mutation V138E leads to partly unfolded PKCγ associated with an exposed C-terminus, altered kinetics, phosphorylation and enhanced insolubilization.

Jezierska J, Goedhart J, Kampinga HH, Reits EA, Verbeek DS.

J Neurochem. 2014 Mar;128(5):741-51. doi: 10.1111/jnc.12491. Epub 2013 Nov 13.

PMID:
24134140
8.

Optimization of fluorescent proteins.

Bindels DS, Goedhart J, Hink MA, van Weeren L, Joosen L, Gadella TW Jr.

Methods Mol Biol. 2014;1076:371-417. doi: 10.1007/978-1-62703-649-8_16.

PMID:
24108635
9.

An introduction to fluorescence imaging techniques geared towards biosensor applications.

Goedhart J, Hink MA, Jalink K.

Methods Mol Biol. 2014;1071:17-28. doi: 10.1007/978-1-62703-622-1_2. Review.

PMID:
24052377
10.

Signaling efficiency of Gαq through its effectors p63RhoGEF and GEFT depends on their subcellular location.

Goedhart J, van Unen J, Adjobo-Hermans MJ, Gadella TW Jr.

Sci Rep. 2013;3:2284. doi: 10.1038/srep02284.

11.

The DNAJB6 and DNAJB8 protein chaperones prevent intracellular aggregation of polyglutamine peptides.

Gillis J, Schipper-Krom S, Juenemann K, Gruber A, Coolen S, van den Nieuwendijk R, van Veen H, Overkleeft H, Goedhart J, Kampinga HH, Reits EA.

J Biol Chem. 2013 Jun 14;288(24):17225-37. doi: 10.1074/jbc.M112.421685. Epub 2013 Apr 23.

12.

PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq.

Adjobo-Hermans MJ, Crosby KC, Putyrski M, Bhageloe A, van Weeren L, Schultz C, Goedhart J, Gadella TW Jr.

Cell Signal. 2013 Jan;25(1):255-63. doi: 10.1016/j.cellsig.2012.09.022. Epub 2012 Sep 21.

PMID:
23006664
13.

Structure of a fluorescent protein from Aequorea victoria bearing the obligate-monomer mutation A206K.

von Stetten D, Noirclerc-Savoye M, Goedhart J, Gadella TW Jr, Royant A.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Aug 1;68(Pt 8):878-82. doi: 10.1107/S1744309112028667. Epub 2012 Jul 26.

14.

Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%.

Goedhart J, von Stetten D, Noirclerc-Savoye M, Lelimousin M, Joosen L, Hink MA, van Weeren L, Gadella TW Jr, Royant A.

Nat Commun. 2012 Mar 20;3:751. doi: 10.1038/ncomms1738.

15.

Quantitative co-expression of proteins at the single cell level--application to a multimeric FRET sensor.

Goedhart J, van Weeren L, Adjobo-Hermans MJ, Elzenaar I, Hink MA, Gadella TW Jr.

PLoS One. 2011;6(11):e27321. doi: 10.1371/journal.pone.0027321. Epub 2011 Nov 17.

16.

Bypassing GPCRs with chemical dimerizers.

Goedhart J, Gadella TW Jr.

Chem Biol. 2011 Sep 23;18(9):1067-8. doi: 10.1016/j.chembiol.2011.09.004. No abstract available.

17.

Understanding why older people develop a wish to die: a qualitative interview study.

Rurup ML, Pasman HR, Goedhart J, Deeg DJ, Kerkhof AJ, Onwuteaka-Philipsen BD.

Crisis. 2011;32(4):204-16. doi: 10.1027/0227-5910/a000078.

PMID:
21940258
18.

Recruiting end-of-life cancer patients in the Netherlands for a study on suffering and euthanasia requests.

Ruijs CD, Goedhart J, Kerkhof AJ, van der Wal G, Onwuteaka-Philipsen BD.

Fam Pract. 2011 Dec;28(6):689-95. doi: 10.1093/fampra/cmr035. Epub 2011 Jun 15.

19.

Real-time visualization of heterotrimeric G protein Gq activation in living cells.

Adjobo-Hermans MJ, Goedhart J, van Weeren L, Nijmeijer S, Manders EM, Offermanns S, Gadella TW Jr.

BMC Biol. 2011 May 27;9:32. doi: 10.1186/1741-7007-9-32.

20.

A mTurquoise-based cAMP sensor for both FLIM and ratiometric read-out has improved dynamic range.

Klarenbeek JB, Goedhart J, Hink MA, Gadella TW, Jalink K.

PLoS One. 2011 Apr 29;6(4):e19170. doi: 10.1371/journal.pone.0019170.

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