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IL-17A induces chromatin remodeling promoting IL-8 release in bronchial epithelial cells: Effect of Tiotropium.

Anzalone G, Gagliardo R, Bucchieri F, Albano GD, Siena L, Montalbano AM, Bonanno A, Riccobono L, Pieper MP, Gjomarkaj M, Profita M.

Life Sci. 2016 Mar 30. pii: S0024-3205(16)30182-5. doi: 10.1016/j.lfs.2016.03.031. [Epub ahead of print]


Airway lipoxin A4/formyl peptide receptor 2-lipoxin receptor levels in pediatric patients with severe asthma.

Gagliardo R, Gras D, La Grutta S, Chanez P, Di Sano C, Albano GD, Vachier I, Montalbano AM, Anzalone G, Bonanno A, Riccobono L, Gjomarkaj M, Profita M.

J Allergy Clin Immunol. 2016 Mar 10. pii: S0091-6749(16)00194-9. doi: 10.1016/j.jaci.2015.11.045. [Epub ahead of print]


Different co-sensitizations could determine different risk assessment in peach allergy? Evaluation of an anaphylactic biomarker in Pru p 3 positive patients.

Uasuf CG, Villalta D, Conte ME, Di Sano C, Barrale M, Cantisano V, Pace E, Gjomarkaj M, Gangemi S, Brusca I.

Clin Mol Allergy. 2015 Dec 2;13:30. doi: 10.1186/s12948-015-0035-7. eCollection 2015.


MD2 expression is reduced in large airways of smokers and COPD smokers.

Pace E, Ferraro M, Chiappara G, Vitulo P, Pipitone L, Di Vincenzo S, Gjomarkaj M.

Mol Cell Biochem. 2015 Sep;407(1-2):289-97. doi: 10.1007/s11010-015-2476-1. Epub 2015 Jun 12.


Cigarette smoke alters the proteomic profile of lung fibroblasts.

D'Anna C, Cigna D, Costanzo G, Bruno A, Ferraro M, Di Vincenzo S, Bianchi L, Bini L, Gjomarkaj M, Pace E.

Mol Biosyst. 2015 Jun;11(6):1644-52. doi: 10.1039/c5mb00188a.


Advances in asthma pathophysiology: stepping forward from the Maurizio Vignola experience.

Bonsignore MR, Profita M, Gagliardo R, Riccobono L, Chiappara G, Pace E, Gjomarkaj M.

Eur Respir Rev. 2015 Mar;24(135):30-9. doi: 10.1183/09059180.10011114. Review.


Budesonide increases TLR4 and TLR2 expression in Treg lymphocytes of allergic asthmatics.

Pace E, Di Sano C, Ferraro M, Bruno A, Caputo V, Gallina S, Gjomarkaj M.

Pulm Pharmacol Ther. 2015 Jun;32:93-100. doi: 10.1016/j.pupt.2015.02.003. Epub 2015 Feb 24.


Cigarette smoke alters cell cycle and induces inflammation in lung fibroblasts.

D'Anna C, Cigna D, Costanzo G, Ferraro M, Siena L, Vitulo P, Gjomarkaj M, Pace E.

Life Sci. 2015 Apr 1;126:10-8. doi: 10.1016/j.lfs.2015.01.017. Epub 2015 Jan 28.


Effects in cigarette smoke stimulated bronchial epithelial cells of a corticosteroid entrapped into nanostructured lipid carriers.

Bondì ML, Ferraro M, Di Vincenzo S, Gerbino S, Cavallaro G, Giammona G, Botto C, Gjomarkaj M, Pace E.

J Nanobiotechnology. 2014 Nov 29;12:46. doi: 10.1186/s12951-014-0046-4.


Fluticasone furoate maintains epithelial homeostasis via leptin/leptin receptor pathway in nasal cells.

Bruno A, Gerbino S, Ferraro M, Siena L, Bonura A, Colombo P, La Grutta S, Gallina S, Ballacchino A, Giammanco M, Gjomarkaj M, Pace E.

Mol Cell Biochem. 2014 Nov;396(1-2):55-65. doi: 10.1007/s11010-014-2142-z. Epub 2014 Jul 29.


Altered expression of p21, activated caspase-3, and PCNA in bronchiolar epithelium of smokers with and without chronic obstructive pulmonary disease.

Chiappara G, Gjomarkaj M, Sciarrino S, Vitulo P, Pipitone L, Pace E.

Exp Lung Res. 2014 Sep;40(7):343-53. doi: 10.3109/01902148.2014.928836. Epub 2014 Jul 24.


Stability of phenotypes defined by physiological variables and biomarkers in adults with asthma.

Kupczyk M, Dahlén B, Sterk PJ, Nizankowska-Mogilnicka E, Papi A, Bel EH, Chanez P, Howarth PH, Holgate ST, Brusselle G, Siafakas NM, Gjomarkaj M, Dahlén SE; BIOAIR investigators.

Allergy. 2014 Sep;69(9):1198-204. doi: 10.1111/all.12445. Epub 2014 Jul 8.


Cigarette smoke alters IL-33 expression and release in airway epithelial cells.

Pace E, Di Sano C, Sciarrino S, Scafidi V, Ferraro M, Chiappara G, Siena L, Gangemi S, Vitulo P, Giarratano A, Gjomarkaj M.

Biochim Biophys Acta. 2014 Sep;1842(9):1630-7. doi: 10.1016/j.bbadis.2014.06.009. Epub 2014 Jun 12.


The relation of airway obstruction to asthma, chronic rhinosinusitis and age: results from a population survey of adults.

Obaseki D, Potts J, Joos G, Baelum J, Haahtela T, Ahlström M, Matricardi P, Kramer U, Gjomarkaj M, Fokkens W, Makowska J, Todo-Bom A, Toren K, Janson C, Dahlen SE, Forsberg B, Jarvis D, Howarth P, Brozek G, Minov J, Bachert C, Burney P; GA2LEN network of excellence.

Allergy. 2014 Sep;69(9):1205-14. doi: 10.1111/all.12447. Epub 2014 Jul 19.


Cigarette smoke alters non-neuronal cholinergic system components inducing MUC5AC production in the H292 cell line.

Montalbano AM, Albano GD, Anzalone G, Bonanno A, Riccobono L, Di Sano C, Gagliardo R, Siena L, Pieper MP, Gjomarkaj M, Profita M.

Eur J Pharmacol. 2014 Aug 5;736:35-43. doi: 10.1016/j.ejphar.2014.04.022. Epub 2014 May 2.


Geographical variation in the prevalence of sensitization to common aeroallergens in adults: the GA(2) LEN survey.

Newson RB, van Ree R, Forsberg B, Janson C, Lötvall J, Dahlén SE, Toskala EM, Baelum J, Brożek GM, Kasper L, Kowalski ML, Howarth PH, Fokkens WJ, Bachert C, Keil T, Krämer U, Bislimovska J, Gjomarkaj M, Loureiro C, Burney PG, Jarvis D.

Allergy. 2014 May;69(5):643-51. doi: 10.1111/all.12397. Epub 2014 Mar 21.


Dual anti-oxidant and anti-inflammatory actions of the electrophilic cyclooxygenase-2-derived 17-oxo-DHA in lipopolysaccharide- and cigarette smoke-induced inflammation.

Cipollina C, Di Vincenzo S, Gerbino S, Siena L, Gjomarkaj M, Pace E.

Biochim Biophys Acta. 2014 Jul;1840(7):2299-309. doi: 10.1016/j.bbagen.2014.02.024. Epub 2014 Mar 2.


Increased levels of Th17 cells are associated with non-neuronal acetylcholine in COPD patients.

Profita M, Albano GD, Riccobono L, Di Sano C, Montalbano AM, Gagliardo R, Anzalone G, Bonanno A, Pieper MP, Gjomarkaj M.

Immunobiology. 2014 May;219(5):392-401. doi: 10.1016/j.imbio.2014.01.004. Epub 2014 Jan 25.


Frequent exacerbators--a distinct phenotype of severe asthma.

Kupczyk M, ten Brinke A, Sterk PJ, Bel EH, Papi A, Chanez P, Nizankowska-Mogilnicka E, Gjomarkaj M, Gaga M, Brusselle G, Dahlén B, Dahlén SE; BIOAIR investigators.

Clin Exp Allergy. 2014 Feb;44(2):212-21. doi: 10.1111/cea.12179.


Clinical relevance is associated with allergen-specific wheal size in skin prick testing.

Haahtela T, Burbach GJ, Bachert C, Bindslev-Jensen C, Bonini S, Bousquet J, Bousquet-Rouanet L, Bousquet PJ, Bresciani M, Bruno A, Canonica GW, Darsow U, Demoly P, Durham SR, Fokkens WJ, Giavi S, Gjomarkaj M, Gramiccioni C, Kowalski ML, Losonczy G, Orosz M, Papadopoulos NG, Stingl G, Todo-Bom A, von Mutius E, Köhli A, Wöhrl S, Järvenpää S, Kautiainen H, Petman L, Selroos O, Zuberbier T, Heinzerling LM.

Clin Exp Allergy. 2014 Mar;44(3):407-16. doi: 10.1111/cea.12240.

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