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Items: 1 to 20 of 112


The fetal thymus has a unique genomic copy number profile resulting from physiological T cell receptor gene rearrangement.

Valind A, Haikal C, Klasson ME, Johansson MC, Gullander J, Soller M, Baldetorp B, Gisselsson D.

Sci Rep. 2016 Mar 24;6:23500. doi: 10.1038/srep23500.


Neuroblastoma patient-derived orthotopic xenografts reflect the microenvironmental hallmarks of aggressive patient tumours.

Braekeveldt N, Wigerup C, Tadeo I, Beckman S, Sandén C, Jönsson J, Erjefält JS, Berbegall AP, Börjesson A, Backman T, Øra I, Navarro S, Noguera R, Gisselsson D, Påhlman S, Bexell D.

Cancer Lett. 2016 Jun 1;375(2):384-9. doi: 10.1016/j.canlet.2016.02.046. Epub 2016 Mar 18.


Aberrant epigenetic regulation in clear cell sarcoma of the kidney featuring distinct DNA hypermethylation and EZH2 overexpression.

Karlsson J, Valind A, Jansson C, O'Sullivan MJ, Holmquist Mengelbier L, Gisselsson D.

Oncotarget. 2016 Mar 8;7(10):11127-36. doi: 10.18632/oncotarget.7152.


Comprehensive genetic analysis of a paediatric pleomorphic myxoid liposarcoma reveals near-haploidization and loss of the RB1 gene.

Hofvander J, Jo VY, Ghanei I, Gisselsson D, Mårtensson E, Mertens F.

Histopathology. 2016 Jul;69(1):141-147. doi: 10.1111/his.12913. Epub 2016 Feb 9.


BCOR internal tandem duplication and YWHAE-NUTM2B/E fusion are mutually exclusive events in clear cell sarcoma of the kidney.

Karlsson J, Valind A, Gisselsson D.

Genes Chromosomes Cancer. 2016 Feb;55(2):120-3. doi: 10.1002/gcc.22316. Epub 2015 Oct 23.


Genetic heterogeneity in rhabdomyosarcoma revealed by SNP array analysis.

Walther C, Mayrhofer M, Nilsson J, Hofvander J, Jonson T, Mandahl N, Øra I, Gisselsson D, Mertens F.

Genes Chromosomes Cancer. 2016 Jan;55(1):3-15. doi: 10.1002/gcc.22285. Epub 2015 Oct 20.


Gene fusion detection in formalin-fixed paraffin-embedded benign fibrous histiocytomas using fluorescence in situ hybridization and RNA sequencing.

Walther C, Hofvander J, Nilsson J, Magnusson L, Domanski HA, Gisselsson D, Tayebwa J, Doyle LA, Fletcher CD, Mertens F.

Lab Invest. 2015 Sep;95(9):1071-6. doi: 10.1038/labinvest.2015.83. Epub 2015 Jun 29.


Multiple mechanisms of MYCN dysregulation in Wilms tumour.

Williams RD, Chagtai T, Alcaide-German M, Apps J, Wegert J, Popov S, Vujanic G, van Tinteren H, van den Heuvel-Eibrink MM, Kool M, de Kraker J, Gisselsson D, Graf N, Gessler M, Pritchard-Jones K.

Oncotarget. 2015 Mar 30;6(9):7232-43.


Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.

Mengelbier LH, Karlsson J, Lindgren D, Valind A, Lilljebjörn H, Jansson C, Bexell D, Braekeveldt N, Ameur A, Jonson T, Kultima HG, Isaksson A, Asmundsson J, Versteeg R, Rissler M, Fioretos T, Sandstedt B, Börjesson A, Backman T, Pal N, Øra I, Mayrhofer M, Gisselsson D.

Nat Commun. 2015 Jan 27;6:6125. doi: 10.1038/ncomms7125.


Activation of human telomerase reverse transcriptase through gene fusion in clear cell sarcoma of the kidney.

Karlsson J, Lilljebjörn H, Holmquist Mengelbier L, Valind A, Rissler M, Øra I, Fioretos T, Gisselsson D.

Cancer Lett. 2015 Feb 28;357(2):498-501. doi: 10.1016/j.canlet.2014.11.057. Epub 2014 Dec 3.


Neuroblastoma patient-derived orthotopic xenografts retain metastatic patterns and geno- and phenotypes of patient tumours.

Braekeveldt N, Wigerup C, Gisselsson D, Mohlin S, Merselius M, Beckman S, Jonson T, Börjesson A, Backman T, Tadeo I, Berbegall AP, Ora I, Navarro S, Noguera R, Påhlman S, Bexell D.

Int J Cancer. 2015 Mar 1;136(5):E252-61. doi: 10.1002/ijc.29217. Epub 2014 Oct 7.


Orthotopic Wilms tumor xenografts derived from cell lines reflect limited aspects of tumor morphology and clinical characteristics.

Mengelbier LH, Bexell D, Sehic D, Ciornei CD, Gisselsson D.

Pediatr Blood Cancer. 2014 Nov;61(11):1949-54. doi: 10.1002/pbc.25131. Epub 2014 Jul 7.


Evaluation of CITED1, SIX1, and CD56 protein expression for identification of blastemal elements in Wilms tumor.

Sehic D, Ciornei CD, Gisselsson D.

Am J Clin Pathol. 2014 Jun;141(6):828-33. doi: 10.1309/AJCPQ8Q0YTHSYZTX.


Reply to Duesberg: Stability of peritriploid and triploid states in neoplastic and nonneoplastic cells.

Valind A, Gisselsson D.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E975. No abstract available.


Reply to Heng: Inborn aneuploidy and chromosomal instability.

Valind A, Gisselsson D.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E973. No abstract available.


Regarding human cytomegalovirus in neuroblastoma.

Forslund O, Holmquist Mengelbier L, Gisselsson D.

Cancer Med. 2014 Aug;3(4):1038-40. doi: 10.1002/cam4.243. Epub 2014 Apr 17.


Confined trisomy 8 mosaicism of meiotic origin: a rare cause of aneuploidy in childhood cancer.

Valind A, Pal N, Asmundsson J, Gisselsson D, Holmquist Mengelbier L.

Genes Chromosomes Cancer. 2014 Jul;53(7):634-8. doi: 10.1002/gcc.22173. Epub 2014 Apr 12.


Clear cell sarcoma of the kidney demonstrates an embryonic signature indicative of a primitive nephrogenic origin.

Karlsson J, Holmquist Mengelbier L, Ciornei CD, Naranjo A, O'Sullivan MJ, Gisselsson D.

Genes Chromosomes Cancer. 2014 May;53(5):381-91. doi: 10.1002/gcc.22149. Epub 2014 Feb 1.


Whole chromosome gain does not in itself confer cancer-like chromosomal instability.

Valind A, Jin Y, Baldetorp B, Gisselsson D.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21119-23. doi: 10.1073/pnas.1311163110. Epub 2013 Dec 9.


Cytogenetic and single nucleotide polymorphism array findings in soft tissue tumors in infants.

Walther C, Nilsson J, von Steyern FV, Wiebe T, Bauer HC, Nord KH, Gisselsson D, Domanski HA, Mandahl N, Mertens F.

Cancer Genet. 2013 Jul-Aug;206(7-8):299-303. doi: 10.1016/j.cancergen.2013.06.004. Epub 2013 Aug 12.

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