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Items: 1 to 20 of 108

1.

RNA splicing is a primary link between genetic variation and disease.

Li YI, van de Geijn B, Raj A, Knowles DA, Petti AA, Golan D, Gilad Y, Pritchard JK.

Science. 2016 Apr 29;352(6285):600-4. doi: 10.1126/science.aad9417. Epub 2016 Apr 28.

PMID:
27126046
2.

Nasal Microbiome Composition Is Associated with Chitotriosidase (Chit1) Activity in Adult Hutterites.

Igartua C, Davenport ER, Chupp GL, Elias JA, Gilad Y, Ober C, Pinto JM.

Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S100-1. doi: 10.1513/AnnalsATS.201508-521MG. No abstract available.

PMID:
27027937
3.

Integrated analyses of gene expression and genetic association studies in a founder population.

Cusanovich DA, Caliskan M, Billstrand C, Michelini K, Chavarria C, De Leon S, Mitrano A, Lewellyn N, Elias JA, Chupp GL, Lang RM, Shah SJ, Decara JM, Gilad Y, Ober C.

Hum Mol Genet. 2016 Feb 29. pii: ddw061. [Epub ahead of print]

4.

Genetic Variation, Not Cell Type of Origin, Underlies the Majority of Identifiable Regulatory Differences in iPSCs.

Burrows CK, Banovich NE, Pavlovic BJ, Patterson K, Gallego Romero I, Pritchard JK, Gilad Y.

PLoS Genet. 2016 Jan 26;12(1):e1005793. doi: 10.1371/journal.pgen.1005793. eCollection 2016 Jan.

5.

Synthesis, biological studies and molecular dynamics of new anticancer RGD-based peptide conjugates for targeted drug delivery.

Gilad Y, Noy E, Senderowitz H, Albeck A, Firer MA, Gellerman G.

Bioorg Med Chem. 2016 Jan 15;24(2):294-303. doi: 10.1016/j.bmc.2015.12.020. Epub 2015 Dec 12.

PMID:
26719208
6.

Dual-drug RGD conjugates provide enhanced cytotoxicity to melanoma and non-small lung cancer cells.

Gilad Y, Noy E, Senderowitz H, Albeck A, Firer MA, Gellerman G.

Biopolymers. 2015 Dec 30. doi: 10.1002/bip.22800. [Epub ahead of print]

PMID:
26715008
7.

A reliable computational workflow for the selection of optimal screening libraries.

Gilad Y, Nadassy K, Senderowitz H.

J Cheminform. 2015 Dec 11;7:61. doi: 10.1186/s13321-015-0108-0. eCollection 2015.

8.

Mycobacterial infection induces a specific human innate immune response.

Blischak JD, Tailleux L, Mitrano A, Barreiro LB, Gilad Y.

Sci Rep. 2015 Nov 20;5:16882. doi: 10.1038/srep16882.

9.

Genome-Wide Association Studies of the Human Gut Microbiota.

Davenport ER, Cusanovich DA, Michelini K, Barreiro LB, Ober C, Gilad Y.

PLoS One. 2015 Nov 3;10(11):e0140301. doi: 10.1371/journal.pone.0140301. eCollection 2015.

10.

msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding.

Raj A, Shim H, Gilad Y, Pritchard JK, Stephens M.

PLoS One. 2015 Sep 25;10(9):e0138030. doi: 10.1371/journal.pone.0138030. eCollection 2015.

11.

Bacterial infection remodels the DNA methylation landscape of human dendritic cells.

Pacis A, Tailleux L, Morin AM, Lambourne J, MacIsaac JL, Yotova V, Dumaine A, Danckaert A, Luca F, Grenier JC, Hansen KD, Gicquel B, Yu M, Pai A, He C, Tung J, Pastinen T, Kobor MS, Pique-Regi R, Gilad Y, Barreiro LB.

Genome Res. 2015 Dec;25(12):1801-11. doi: 10.1101/gr.192005.115. Epub 2015 Sep 21.

PMID:
26392366
12.

WASP: allele-specific software for robust molecular quantitative trait locus discovery.

van de Geijn B, McVicker G, Gilad Y, Pritchard JK.

Nat Methods. 2015 Nov;12(11):1061-3. doi: 10.1038/nmeth.3582. Epub 2015 Sep 14.

13.

Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages.

Frankenberger C, Rabe D, Bainer R, Sankarasharma D, Chada K, Krausz T, Gilad Y, Becker L, Rosner MR.

Cancer Res. 2015 Oct 1;75(19):4063-73. doi: 10.1158/0008-5472.CAN-14-3394. Epub 2015 Aug 3.

PMID:
26238785
14.

A reanalysis of mouse ENCODE comparative gene expression data.

Gilad Y, Mizrahi-Man O.

F1000Res. 2015 May 19;4:121. doi: 10.12688/f1000research.6536.1. eCollection 2015.

15.

A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics.

Gallego Romero I, Pavlovic BJ, Hernando-Herraez I, Zhou X, Ward MC, Banovich NE, Kagan CL, Burnett JE, Huang CH, Mitrano A, Chavarria CI, Friedrich Ben-Nun I, Li Y, Sabatini K, Leonardo TR, Parast M, Marques-Bonet T, Laurent LC, Loring JF, Gilad Y.

Elife. 2015 Jun 23;4:e07103. doi: 10.7554/eLife.07103.

16.

Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature.

Thomas SM, Kagan C, Pavlovic BJ, Burnett J, Patterson K, Pritchard JK, Gilad Y.

PLoS Genet. 2015 May 7;11(5):e1005216. doi: 10.1371/journal.pgen.1005216. eCollection 2015 May.

17.

Host genetic variation influences gene expression response to rhinovirus infection.

Çalışkan M, Baker SW, Gilad Y, Ober C.

PLoS Genet. 2015 Apr 13;11(4):e1005111. doi: 10.1371/journal.pgen.1005111. eCollection 2015 Apr.

18.

The genetic architecture of gene expression levels in wild baboons.

Tung J, Zhou X, Alberts SC, Stephens M, Gilad Y.

Elife. 2015 Feb 25;4. doi: 10.7554/eLife.04729.

19.

Genomic variation. Impact of regulatory variation from RNA to protein.

Battle A, Khan Z, Wang SH, Mitrano A, Ford MJ, Pritchard JK, Gilad Y.

Science. 2015 Feb 6;347(6222):664-7. doi: 10.1126/science.1260793. Epub 2014 Dec 18.

20.

The genetic and mechanistic basis for variation in gene regulation.

Pai AA, Pritchard JK, Gilad Y.

PLoS Genet. 2015 Jan 8;11(1):e1004857. doi: 10.1371/journal.pgen.1004857. eCollection 2015 Jan.

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