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Items: 1 to 20 of 109

1.

A novel in vitro platform for the study of SN38-induced mucosal damage and the development of Toll-like receptor 4-targeted therapeutic options.

Wardill HR, Gibson RJ, Van Sebille YZ, Secombe KR, Logan RM, Bowen JM.

Exp Biol Med (Maywood). 2016 Mar 31. pii: 1535370216640932. [Epub ahead of print]

PMID:
27037276
2.

Gastrointestinal toxicities of first and second-generation small molecule human epidermal growth factor receptor tyrosine kinase inhibitors in advanced nonsmall cell lung cancer.

Van Sebille YZ, Gibson RJ, Wardill HR, Bowen JM.

Curr Opin Support Palliat Care. 2016 Jun;10(2):152-6. doi: 10.1097/SPC.0000000000000210. No abstract available.

PMID:
27035390
3.

Radiotherapy-induced gut toxicity: Involvement of matrix metalloproteinases and the intestinal microvasculature.

Stansborough RL, Al-Dasooqi N, Bateman EH, Keefe DM, Gibson RJ.

Int J Radiat Biol. 2016 Feb 26:1-8. [Epub ahead of print]

PMID:
26917115
4.

Chemotherapy-induced gut toxicity and pain: involvement of TLRs.

Gibson RJ, Coller JK, Wardill HR, Hutchinson MR, Smid S, Bowen JM.

Support Care Cancer. 2016 May;24(5):2251-8. doi: 10.1007/s00520-015-3020-2. Epub 2015 Nov 19.

PMID:
26581898
5.

Tight junction defects are seen in the buccal mucosa of patients receiving standard dose chemotherapy for cancer.

Wardill HR, Logan RM, Bowen JM, Van Sebille YZ, Gibson RJ.

Support Care Cancer. 2016 Apr;24(4):1779-88. doi: 10.1007/s00520-015-2964-6. Epub 2015 Oct 6.

PMID:
26441079
6.

Management of Mucositis During Chemotherapy: From Pathophysiology to Pragmatic Therapeutics.

Van Sebille YZ, Stansborough R, Wardill HR, Bateman E, Gibson RJ, Keefe DM.

Curr Oncol Rep. 2015 Nov;17(11):50. doi: 10.1007/s11912-015-0474-9.

PMID:
26384312
7.

What are the predictive factors in the risk and severity of chemotherapy-induced gastrointestinal toxicity?

Gibson RJ, Bowen JM, Coller JK.

Future Oncol. 2015;11(17):2367-70. doi: 10.2217/FON.15.138. Epub 2015 Aug 13. No abstract available.

8.

ErbB small molecule tyrosine kinase inhibitor (TKI) induced diarrhoea: Chloride secretion as a mechanistic hypothesis.

Van Sebille YZ, Gibson RJ, Wardill HR, Bowen JM.

Cancer Treat Rev. 2015 Jul;41(7):646-52. doi: 10.1016/j.ctrv.2015.05.011. Epub 2015 Jun 6. Review.

PMID:
26073491
9.

Editorial Comment: Does gut-derived inflammation enhance pain signaling following chemotherapy in a Toll-like receptor 4-dependent manner?

Wardill HR, Van Sebille YZ, Bowen JM, Gibson RJ.

Curr Opin Support Palliat Care. 2015 Jun;9(2):155-6. doi: 10.1097/SPC.0000000000000139. No abstract available.

PMID:
25872125
10.

Caffeic acid phenethyl ester abrogates bone resorption in a murine calvarial model of polyethylene particle-induced osteolysis.

Zawawi MS, Perilli E, Stansborough RL, Marino V, Cantley MD, Xu J, Dharmapatni AA, Haynes DR, Gibson RJ, Crotti TN.

Calcif Tissue Int. 2015 Jun;96(6):565-74. doi: 10.1007/s00223-015-9982-8. Epub 2015 Mar 25.

PMID:
25804981
11.

Toll-like receptor 4 signaling: a common biological mechanism of regimen-related toxicities: an emerging hypothesis for neuropathy and gastrointestinal toxicity.

Wardill HR, Van Sebille YZ, Mander KA, Gibson RJ, Logan RM, Bowen JM, Sonis ST.

Cancer Treat Rev. 2015 Feb;41(2):122-8. doi: 10.1016/j.ctrv.2014.11.005. Epub 2014 Dec 5. Review.

PMID:
25512119
12.

Involvement of matrix metalloproteinases (MMP-3 and MMP-9) in the pathogenesis of irinotecan-induced oral mucositis.

Al-Azri AR, Gibson RJ, Bowen JM, Stringer AM, Keefe DM, Logan RM.

J Oral Pathol Med. 2015 Jul;44(6):459-67. doi: 10.1111/jop.12255. Epub 2014 Sep 12.

PMID:
25213123
13.

Why continual update of clinical practice guidelines for cytotoxic therapy-induced mucositis is essential.

Gibson RJ.

Curr Opin Support Palliat Care. 2014 Sep;8(3):316-8. doi: 10.1097/SPC.0000000000000036. No abstract available.

PMID:
24503646
14.

Gastrointestinal mucositis: the role of MMP-tight junction interactions in tissue injury.

Al-Dasooqi N, Wardill HR, Gibson RJ.

Pathol Oncol Res. 2014 Jul;20(3):485-91. doi: 10.1007/s12253-013-9733-y. Epub 2014 Jan 15. Review.

PMID:
24424533
15.

New pharmacotherapy options for chemotherapy-induced alimentary mucositis.

Wardill HR, Bowen JM, Gibson RJ.

Expert Opin Biol Ther. 2014 Mar;14(3):347-54. doi: 10.1517/14712598.2014.874412. Epub 2014 Jan 6. Review.

PMID:
24387716
16.

Irinotecan disrupts tight junction proteins within the gut : implications for chemotherapy-induced gut toxicity.

Wardill HR, Bowen JM, Al-Dasooqi N, Sultani M, Bateman E, Stansborough R, Shirren J, Gibson RJ.

Cancer Biol Ther. 2014 Feb;15(2):236-44. doi: 10.4161/cbt.27222. Epub 2013 Dec 6.

17.

TLR4/PKC-mediated tight junction modulation: a clinical marker of chemotherapy-induced gut toxicity?

Wardill HR, Gibson RJ, Logan RM, Bowen JM.

Int J Cancer. 2014 Dec 1;135(11):2483-92. doi: 10.1002/ijc.28656. Epub 2014 Jan 10. Review.

18.

Accurate identification of deamidated peptides in global proteomics using a quadrupole orbitrap mass spectrometer.

Nepomuceno AI, Gibson RJ, Randall SM, Muddiman DC.

J Proteome Res. 2014 Feb 7;13(2):777-85. doi: 10.1021/pr400848n. Epub 2013 Dec 12.

19.

Emerging evidence on the pathobiology of mucositis.

Al-Dasooqi N, Sonis ST, Bowen JM, Bateman E, Blijlevens N, Gibson RJ, Logan RM, Nair RG, Stringer AM, Yazbeck R, Elad S, Lalla RV; Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO).

Support Care Cancer. 2013 Nov;21(11):3233-41. doi: 10.1007/s00520-013-1900-x. Epub 2013 Jul 11. Review.

PMID:
23842598
20.

Detecting gut injury during chemotherapy: is a breath test the answer?

Wardill HR, Gibson RJ.

Future Oncol. 2013 Sep;9(9):1245-7. doi: 10.2217/fon.13.93. Epub 2013 May 21. No abstract available.

PMID:
23692047
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