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Items: 1 to 20 of 27

1.

Evidence for a quadruplex structure in the polymorphic hs1.2 enhancer of the immunoglobulin heavy chain 3' Regulatory Regions and its conservation in mammals.

Sette M, D'Addabbo P, Kelly G, Cicconi A, Micheli E, Cacchione S, Poma A, Gargioli C, Giambra V, Frezza D.

Biopolymers. 2016 Jun 10. doi: 10.1002/bip.22891. [Epub ahead of print]

PMID:
27287611
2.

Targeting leukemia stem cells: which pathways drive self-renewal activity in T-cell acute lymphoblastic leukemia?

Belmonte M, Hoofd C, Weng AP, Giambra V.

Curr Oncol. 2016 Feb;23(1):34-41. doi: 10.3747/co.23.2806. Epub 2016 Feb 18. Review.

3.

CD44 promotes chemoresistance in T-ALL by increased drug efflux.

Hoofd C, Wang X, Lam S, Jenkins C, Wood B, Giambra V, Weng AP.

Exp Hematol. 2016 Mar;44(3):166-171.e17. doi: 10.1016/j.exphem.2015.12.001. Epub 2015 Dec 18.

PMID:
26708679
4.

Leukemia stem cells in T-ALL require active Hif1α and Wnt signaling.

Giambra V, Jenkins CE, Lam SH, Hoofd C, Belmonte M, Wang X, Gusscott S, Gracias D, Weng AP.

Blood. 2015 Jun 18;125(25):3917-27. doi: 10.1182/blood-2014-10-609370. Epub 2015 May 1.

5.

The change in Ig regulation from children to adults disconnects the correlation with the 3'RR hs1.2 polymorphism.

Serone E, Daleno C, Principi N, Porretti L, Iacoacci V, Gargioli C, Magrini A, Massoud R, D'Addabbo P, Cattalini M, Giambra V, Plebani A, Esposito S, Frezza D.

BMC Immunol. 2014 Nov 13;15:45. doi: 10.1186/s12865-014-0045-0.

6.

The functional VNTR of IGH enhancer HS1.2 associates with human longevity and interacts with TNFA promoter diplotype in a population of Central Italy.

Napolioni V, Serone E, Iacoacci V, Carpi FM, Giambra V, Frezza D.

Gene. 2014 Nov 10;551(2):201-5. doi: 10.1016/j.gene.2014.08.057. Epub 2014 Aug 28.

PMID:
25175451
7.

HS1,2 Ig enhancer alleles association to AIDS progression in a pediatric cohort infected with a monophyletic HIV-strain.

Montesano C, Giambra V, Frezza D, Palma P, Serone E, Gattinara GC, Mattei M, Mancino G, Colizzi V, Amicosante M.

Biomed Res Int. 2014;2014:637523. doi: 10.1155/2014/637523. Epub 2014 May 20.

8.

NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species.

Giambra V, Jenkins CR, Wang H, Lam SH, Shevchuk OO, Nemirovsky O, Wai C, Gusscott S, Chiang MY, Aster JC, Humphries RK, Eaves C, Weng AP.

Nat Med. 2012 Nov;18(11):1693-8. doi: 10.1038/nm.2960. Epub 2012 Oct 21.

9.

IGF signaling contributes to malignant transformation of hematopoietic progenitors by the MLL-AF9 oncoprotein.

Jenkins CR, Shevchuk OO, Giambra V, Lam SH, Carboni JM, Gottardis MM, Holzenberger M, Pollak M, Humphries RK, Weng AP.

Exp Hematol. 2012 Sep;40(9):715-723.e6. doi: 10.1016/j.exphem.2012.05.003. Epub 2012 May 18.

PMID:
22613471
10.

Polymorphisms of the IgH enhancer HS1.2 and risk of systemic lupus erythematosus.

Frezza D, Tolusso B, Giambra V, Gremese E, Marchini M, Nowik M, Serone E, D'Addabbo P, Mattioli C, Canestri S, Petricca L, D'Antona G, Birshtein BK, Scorza R, Ferraccioli G.

Ann Rheum Dis. 2012 Aug;71(8):1309-15. doi: 10.1136/ard.2010.147025. Epub 2012 Jan 31.

PMID:
22294636
11.

Position and sequence conservation in Amniota of polymorphic enhancer HS1.2 within the palindrome of IgH 3'Regulatory Region.

D'Addabbo P, Scascitelli M, Giambra V, Rocchi M, Frezza D.

BMC Evol Biol. 2011 Mar 15;11:71. doi: 10.1186/1471-2148-11-71.

12.

Comprehensive microRNA expression profiling of the hematopoietic hierarchy.

Petriv OI, Kuchenbauer F, Delaney AD, Lecault V, White A, Kent D, Marmolejo L, Heuser M, Berg T, Copley M, Ruschmann J, Sekulovic S, Benz C, Kuroda E, Ho V, Antignano F, Halim T, Giambra V, Krystal G, Takei CJ, Weng AP, Piret J, Eaves C, Marra MA, Humphries RK, Hansen CL.

Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15443-8. doi: 10.1073/pnas.1009320107. Epub 2010 Aug 11.

13.

Allele *1 of HS1.2 enhancer associates with selective IgA deficiency and IgM concentration.

Giambra V, Cianci R, Lolli S, Mattioli C, Tampella G, Cattalini M, Kilic SS, Pandolfi F, Plebani A, Frezza D.

J Immunol. 2009 Dec 15;183(12):8280-5. doi: 10.4049/jimmunol.0902426.

14.

Allelic frequencies of 3' Ig heavy chain locus enhancer HS1,2-A associated with Ig levels in patients with schizophrenia.

Frezza D, Giambra V, Mattioli C, Piccoli K, Massoud R, Siracusano A, Di Giannantonio M, Birshtein BK, Rubino IA.

Int J Immunopathol Pharmacol. 2009 Jan-Mar;22(1):115-23.

15.

Allele *2 of the HS1,2A enhancer of the Ig regulatory region associates with rheumatoid arthritis.

Tolusso B, Frezza D, Mattioli C, Fedele AL, Bosello S, Faustini F, Peluso G, Giambra V, Pietrapertosa D, Morelli A, Gremese E, De Santis M, Ferraccioli GF.

Ann Rheum Dis. 2009 Mar;68(3):416-9. doi: 10.1136/ard.2008.095414. Epub 2008 Oct 24.

16.

Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3' regulatory region of the immunoglobulin heavy chain locus.

Giambra V, Volpi S, Emelyanov AV, Pflugh D, Bothwell AL, Norio P, Fan Y, Ju Z, Skoultchi AI, Hardy RR, Frezza D, Birshtein BK.

Mol Cell Biol. 2008 Oct;28(19):6123-33. doi: 10.1128/MCB.00233-08. Epub 2008 Jul 21.

17.

The lens-regenerating competence in the outer cornea and epidermis of larval Xenopus laevis is related to pax6 expression.

Gargioli C, Giambra V, Santoni S, Bernardini S, Frezza D, Filoni S, Cannata SM.

J Anat. 2008 May;212(5):612-20. doi: 10.1111/j.1469-7580.2008.00891.x.

18.

Increased frequency of Ig heavy-chain HS1,2-A enhancer *2 allele in dermatitis herpetiformis, plaque psoriasis, and psoriatic arthritis.

Cianci R, Giambra V, Mattioli C, Esposito M, Cammarota G, Scibilia G, Magazzù G, Orlando A, Sandri G, Bianchi L, Gasbarrini GB, Pandolfi F, Frezza D.

J Invest Dermatol. 2008 Aug;128(8):1920-4. doi: 10.1038/jid.2008.40. Epub 2008 Mar 6.

19.

Polymorphisms of the COL1A2, CYP1A1 and HS1,2 Ig enhancer genes in the Tuaregs from Libya.

Martinez-Labarga C, Lelli R, Tarsi T, Babalini C, De Angelis F, Ottoni C, Giambra V, Pepe G, Azebi E, Frezza D, Biondi G, Rickards O.

Ann Hum Biol. 2007 Jul-Aug;34(4):425-36.

PMID:
17620151
20.

Activatory properties of lysophosphatidic acid on human THP-1 cells.

D'Aquilio F, Procaccini M, Izzi V, Chiurchiu' V, Giambra V, Carotenuto F, Di Nardo P, Baldini PM.

Inflammation. 2007 Oct;30(5):167-77.

PMID:
17594136
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